Clinical trials: Combined Spinal Epidural Anesthesia
Cesarean Section
Fluid Management for Cesarean Section III
Regional anesthesia, including epidural, spinal and combined epidural spinal anesthesia (CSEA), is a pivotal part in modern anesthesiology.
- Trial name
- FMCS-III (NCT00973414)
- Testing
- Ringer's Lactate, Six percent hydroxyethyl starch
- Where
- China
- Volunteers
- 850 people
- Sponsor
- Nanjing Medical University
Anesthesia, Analgesia
Conversion of Labor Analgesia for Intrapartum Cesarean Delivery: DPE v CSE v Epidural
As the dural puncture epidural (DPE) is increasing in popularity for labor analgesia, it is important to understand how it impacts outcomes in parturients.
- Trial name
- NCT05514431
- Testing
- Epidural, Dural Puncture Epidural (DPE) technique, Combined Spinal-Epidural (CSE) technique
- Where
- 2 sites in United States, Canada
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Labor Long, Labor Pain
Comparison of Combined Spinal-epidural Analgesia Versus Epidural Analgesia for Pain Management During Labor
The investigators want to compare the safety and efficacy between the combined spinal-epidural analgesia and epidural analgesia during labor.
- Conditions
- Labor Long, Labor Pain, Labor Fetal Anoxia
- Trial name
- NCT03600272
- Testing
- Combined spinal-epidural analgesia, Epidural analgesia
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Deng Dongrui
Labor Pain
Quality of Labour Epidural Analgesia With Intrathecal Morphine as a Component of Combined Spinal Epidural
Neuraxial analgesia has shown to be the gold standard for effective labor pain relief, offering numerous benefits including enhanced pain control and maternal satisfaction.
- Trial name
- NCT06572241
- Testing
- Intrathecal morphine
- Where
- Canada
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Regional Anesthesia Morbidity, Ultrasonography
Ultrasound-guided Combined Spinal-epidural Anesthesia: Pre-procedure Versus Real-time Scan
The investigators will compare the success rate, the consumed time, the number of needle passing, the depth and angle of the needle, the anesthetic effect, complications, pain and patient's satisfaction between 'Real-time scan'…
- Trial name
- NCT03805958
- Testing
- realtime ultrasonography, prescan ultrasonography
- Volunteers
- 56 people
- Sponsor
- Seoul National University Hospital
Labor Pain, Pain
The Effects of Intermittent Epidural Bolus on Fever During Labor Analgesia
Epidural analgesia is associated with maternal intra-partum fever during labor. Intermittent epidural injections appear to reduce the incidence of maternal intra-partum fever compared to continuous epidural infusion during labor…
- Conditions
- Labor Pain, Pain, Neurologic Manifestations, Signs and Symptoms
- Trial name
- EIEBFLA (NCT01708668)
- Testing
- Epidural analgesia, Combined spinal-epidural analgesia, Continuous epidural infusion
- Where
- China
- Volunteers
- 12,000 people
- Sponsor
- ShanWu Feng, M.D.
Spinal Anesthesia, Epidural; Anesthesia
Bupivacaine With Epidural Volume Extension
In this study the investigator will address the efficacy of using low dose bupivacaine spinal anesthesia (SA) in combination with epidural volume extension (EVE) for patients undergoing short obstetric procedures.
- Trial name
- NCT03110003
- Testing
- 10 mg Bupivacaine, 5 mg Bupivacaine
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Obstetric Pain, Analgesia
Study Comparing Dural Puncture Epidural With Epidural and Combined Spinal Epidural Anesthesia for Obstetric Analgesia.
This will be a prospective, randomized, double blind, controlled clinical trial. Epidural analgesia (EP) is currently the method of choice to ensure the comfort of the parturient during childbirth.
- Trial name
- NCT05196256
- Testing
- Dural puncture, Combined spinal epidural analgesia, Epidural analgesia
- Where
- Belgium
- Volunteers
- 90 people
- Sponsor
- Brugmann University Hospital
Combination of General Anesthesia to Spinal and Epidural Techniques
Combination of Spinal-Epidural With General Anesthesia in Patients Undergoing Mega-Liposuction Surgery
The combination of general anesthesia to spinal and epidural techniques (CSEGA) proved to have a synergistic effect, thus, the use of sub-anesthetic doses can provide satisfactory anesthetic and analgesic results.
- Trial name
- NCT05301127
- Testing
- spinal-epidural device
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
LABOR PAIN
Optimal Regimen of Patient-controlled Epidural Analgesia in Laboring Patients
To test the efficacy of different recipes of epidural infusions used for providing pain relief during labor in parturients.
- Trial name
- PCEA (NCT03566342)
- Volunteers
- 145 people
- Sponsor
- Maimonides Medical Center
Pain, Postoperative, Osteoarthritis
Pain Treatment After Total Knee Replacement - Continuous Epidural Versus Intravenous Patient Controlled Analgesia With Morphine
The study purpose is to compare the effectiveness of different methods for post-operative pain treatment after total knee replacement.
- Trial name
- NCT00270322
- Testing
- Marcaine 0.166% + Fentanyl 3.33 mcg/ml, Morphine sulphate
- Where
- Israel
- Volunteers
- 80 people
- Sponsor
- Rambam Health Care Campus
Cesarean Section Complications
Effect of Three Weight-adjusted Vasopressors for Elective Cesarean Delivery
This study compared the effects of prophylactic infusion of metaraminol, phenylephrine and norepinephrine adjusted according to body weight on fetal acid-base balance and maternal hemodynamics.
- Trial name
- NCT04991662
- Testing
- metaraminol, Phenylephrine, Norepinephrine
- Where
- China
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Xuzhou Medical University
Obesity, Pregnancy Related
Combined Spinal Epidural Anesthesia in Obese Patients Undergoing Cesarean Surgery
This study investigated the maternal and fetal effects during performance of CSEA in the left lateral decubitus and sitting positions in obese pregnant women undergoing elective cesarean section.
- Conditions
- Obesity, Pregnancy Related, Cesarean Section Complications, Spinal Anaesthetic Poisoning of Undetermined Intent
- Trial name
- NCT04612998
- Testing
- left lateral decubitus position, sitting position, The use of intravenous ephedrine.
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Anesthesia,Obstetrical
Palpation and ACCURO for Placing Spinal in C-section
The Accuro is a three dimensional handheld ultrasound device. This device uses sound waves to create pictures of the spine in three dimensions.
- Trial name
- NCT03090295
- Testing
- Palpation and Accuro
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Virginia
Cesarean Section, Anesthesia, Spinal
Combined Spinal-epidural Anesthesia for Cesarean Section Without Prophylactical Prehydration and Vasopressors
Hypotension is a common complication in pregnant women after spinal anesthesia and related with the dose of local anesthetic. Injecting small dose local anesthetic into subarachnoid space can decrease the incidence of…
- Trial name
- CSEAFCSWPPAV (NCT03497364)
- Testing
- bupivacaine, ropivacaine
- Where
- China
- Volunteers
- 930 people
- Sponsor
- Shenzhen People's Hospital
Effects of; Anesthesia, in Labor and Delivery, Pregnancy
Effects of Analgesic Techniques on Duration of Labor for Induction Patients
The purpose of this study is to determine if there is a difference in the duration of the first stage of labor in nulliparous women scheduled for an induction of labor, with whom analgesia is maintained with a combined spinal…
- Conditions
- Effects of; Anesthesia, in Labor and Delivery, Pregnancy, Prolonged First Stage of Labor
- Trial name
- NCT01982851
- Testing
- Epidural de novo, CSE
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Anesthesia, Analgesia
The Impact of the Anaesthetic Technique Employed on the Quality of Recovery in Patients Undergoing Hysterectomy Surgery.
The objective of this study is to evaluate the results of different anesthesia methods (general anesthesia with epidural catheter application and spinal anesthesia with epidural catheter application) applied in elective…
- Conditions
- Anesthesia, Analgesia, Acute Pain
- Trial name
- NCT06461832
- Testing
- Group 1, Group 2
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people
- Sponsor
- Samsun University
Labour Pain
Combined Spinal-Epidural Versus Traditional Labor Epidural
The purpose of this study to compare the use of spinal-epidural versus traditional labor epidural on maternal and fetal effects.
- Trial name
- NCT00151346
- Testing
- Bupivacaine and Fentanyl (for CSE), Bupivacaine and Fentanyl (for traditional epidural)
- Where
- United States
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Pregnancy, Breech Presentation
The Effect of Combined Spinal-Epidural Analgesia on the Success of External Cephalic Version (ECV) for Breech Position
We aim to answer the clinical question: Does combined spinal-epidural analgesia improve the success rate of external cephalic version? We hypothesize that neuraxial analgesia (spinal or epidural analgesia) during version for…
- Trial name
- Version (NCT00565383)
- Testing
- Combined spinal-epidural analgesia, Intravenous fentanyl (50mcg)
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Northwestern University
Pain, Postoperative
Different Epidural Initiation Volumes
The aim of this study is to compare the effect of different epidural initiation volumes on postoperative pain scores, local anesthetic requirements, and motor block in patients who undergo patient controlled epidural analgesia…
- Trial name
- NCT03156322
- Testing
- 5 mL epidural initiation volume (bupivacaine + fentanyl), 10 mL epidural initiation volume (bupivacaine + fentanyl), 20 mL epidural initiation volume (bupivacaine + fentanyl)
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- Inonu University