Clinical trials: Comfort
Multiple Sclerosis
The Multicenter, Open-label, Single-use Autoinjector Convenience Study
The purpose of this trial is to test the Single-Use Autoinjector for a) ease of use; b) multiple domains related to subject's acceptability and satisfaction, and c) reliability of the correct function for self-injection of Rebif®…
- Trial name
- NCT00958009
- Testing
- Rebidose®
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- EMD Serono
Claustrophobia, Complication of Diagnostic Procedure
Reduction of Claustrophobia and Patient Motion After Training of MRI Personnel in Comfort TalkTM
Annually, an estimated 700,000 patients do not complete their scheduled MRI scans because of claustrophobia or inability to hold still.
- Trial name
- NCT01563198
- Testing
- Comfort Talk®
- Where
- 4 sites in United States
- Volunteers
- 97,712 people
- Sponsor
- Hypnalgesics, LLC
Hyperphosphataemia, ESRD
Non-interventional Study to Evaluate the Ease of Reaching Individual Goals in Serum Phosphorus (Steering)
The objective of this non-interventional study is to confirm that with standard OsvaRen® treatment it is possible to achieve in at least 60% of the patients the levels of phosphorus, total calcium, and iPTH seen in the CALMAG…
- Trial name
- Steering (NCT01424787)
- Where
- 24 sites in Denmark, Germany and 2 more
- Volunteers
- 324 people
- Sponsor
- Fresenius Medical Care Deutschland GmbH
Diabetes Mellitus Type 2
Ease of Use and Safety of the New U300 Pen Injector in Insulin-Naïve Patients With T2DM
Primary Objective: To demonstrate the ease of use of the U300 pen injector in pen-naïve and insulin-naïve type 2 diabetes mellitus (T2DM) patients in a 4-week once-daily dosing regimen with HOE901-U300.
- Trial name
- NCT02227212
- Testing
- Insulin glargine U300 (new formulation of insulin glargine) HOE901
- Where
- 7 sites in Germany
- Volunteers
- 40 people
- Sponsor
- Sanofi
Myopia, Refractive Error
Multi-Center Clinical Evaluation of Two Daily Disposable Contact Lenses
The purpose of this study is to compare the subjective performance of two daily disposable contact lenses with respect to comfort and handling.
- Trial name
- NCT01898260
- Testing
- Ultrafilcon B contact lens, Stenfilcon A contact lens
- Where
- United Kingdom
- Volunteers
- 89 people
- Sponsor
- Alcon Research
Infectious Diseases
Evaluating Patient Comfort and Environmental Conditions in the Carecube Negative Pressure Isolation Chamber.1
This is a human non-significant risk (NSR) clinical study designed to objectively and participatively verify that the Carecube Negative Pressure Isolation Chamber is a safe and non-hostile environment for the patients that will…
- Trial name
- NCT05468723
- Testing
- Carecube Negative Pressure Isolation Chamber
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Carecubes, Inc.
Incisional Hernia, Ventral Hernia
Flexible Composite Next Generation Tissue Separating Mesh in Laparoscopic Incisional/Ventral Hernia Repair
This is a multi-center, observational study of incisional/ventral hernia repair with NG-TSM laparoscopically. The study is not randomized and has a single treatment design assessing NG-TSM intra-operatively, its ease of use and…
- Trial name
- NCT01162564
- Testing
- NG-TSM
- Where
- 6 sites in United States
- Volunteers
- 48 people
- Sponsor
- Ethicon, Inc.
Dry Eye
Acute Comfort and Blur Profile of a Lubricant Eye Drop Versus a Marketed Eye Ointment
The purpose of this study is to compare the comfort and blurriness of the investigational lubricant eye drop with a marketed artificial tear ointment.
- Trial name
- NCT01076998
- Testing
- Lubricant eye drop FID 115958D, Refresh PM Ointment
- Volunteers
- 24 people
- Sponsor
- Alcon Research
Constipation, Gastrointestinal Discomfort
Clinical Evaluation of the Effects of EpiCor on Digestive Comfort
Previous in vitro studies suggest that EpiCor is well fermented in the colon and has prebiotic potential. The repeated long-term administration of low doses of EpiCor in the Simulator of the Human Intestinal Microbial Ecosystem…
- Trial name
- NCT03051399
- Testing
- EpiCor
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- ProDigest
Myopia
Lens Wear Schedules and End-of-Day Comfort
The purpose of this study was to assess the impact of lens-free (recovery) intervals of varying lengths on end-of-day comfort and tear film changes with daily contact lens wear.
- Trial name
- INVERMERE (NCT01433549)
- Testing
- Lotrafilcon B, Senofilcon A
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- CIBA VISION
Open-Angle Glaucoma, Ocular Hypertension
A Single Dose Comfort Comparison of Travatan Z in One Eye Versus Xalatan in the Opposite Eye in Patients With Primary Open-Angle Glaucoma or Ocular Hypertension
The purpose of this study is to compare the comfort of Travatan Z in one eye and Xalatan in the opposite eye in patients with primary open-angle glaucoma or ocular hypertension.
- Trial name
- NCT00527592
- Testing
- Travoprost ophthalmic solution 0.004% with SofZia® preservative system (TRAVATAN Z®), Latanoprost ophthalmic solution 0.005% (XALATAN®)
- Volunteers
- 54 people
- Sponsor
- Alcon Research
Lean Muscle Development, Muscular Endurance
A Clinical Trial to Evaluate the Effects of a Powder Supplement in Supporting Lean Muscle Development, Hormone-Related Wellness, Digestive Comfort, Dermatologic Health, and Overall Wellness
This study will evaluate the effects of Clean Nutra's Shelf Builder Women's Creatine Powder on lean muscle development, hormone-related wellness, digestive comfort, dermatological health, and overall wellness.
- Conditions
- Lean Muscle Development, Muscular Endurance, Hormone-Related Wellness, Digestive Comfort
- Trial name
- NCT07766395
- Testing
- Shelf Builder Women's Creatine Powder
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Clean Nutraceuticals
Gastrointestinal Diseases, Infant Nutrition Disorders
GI Symptoms in Infants Fed GMF or CMF
The aim of this study was to assess common gastrointestinal symptoms in healthy Brazilian infants receiving goat milk-based infant formula (GMF) compared to cow's milk-based infant formula (CMF) during a 24 week intervention.
- Trial name
- NCT06395571
- Testing
- Goat milk-based infant formula, Cow's milk-based infant formula
- Where
- Brazil
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Ausnutria Hyproca B.V.
Dementia, Alzheimer Disease
All About Me: An Intervention to Ease the Transition to Long Term Care
This Phase I study will involve initial development and evaluation of an innovative cross-platform software app called All About Me (AAM), which will consist of Serious Digital Health Games (SDHGs) for PWD.
- Conditions
- Dementia, Alzheimer Disease, Dementia, Vascular, Dementia, Mixed
- Trial name
- AAM (NCT05516134)
- Testing
- SAFE at Home
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Hopeful Aging
Healthy
Effects of Low Lactose Milk Containing GOS on Digestive Response in Healthy Chinese Adults
We are aiming to assess the effects of low lactose milk containing galactooligosaccharides (GOS) on digestive response in healthy Chinese adults in comparison with a matching milk containing lactose.
- Trial name
- MilkRI (NCT06598124)
- Testing
- Investigational Product (IP), Comparator Product (CP)
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Multiple Sclerosis, Relapsing-Remitting
Rebif® Rebidose® Versus Rebiject II® Ease-of-Use
This is a Phase 4, prospective, open-label, randomized, cross-over, multicenter trial to evaluate ease-of-use with Rebif® Rebidose® and Rebiject II® autoinjectors in subjects with relapsing remitting multiple sclerosis (RRMS).
- Trial name
- NCT02019550
- Testing
- Rebif Rebidose, Rebiject II
- Where
- 21 sites in United States
- Volunteers
- 97 people
- Sponsor
- EMD Serono
Opioid Dependence
Usability of Zubsolv Sublingual Tablets 5.7/1.4 to Suboxone Sublingual Film 8/2 In Buprenorphine/Naloxone Treated Opioid Dependent Population
The primary objective of this study is to compare overall patient preference for either Suboxone® sublingual film 8/2 or Zubsolv® sublingual tablets 5.7/1.4.
- Trial name
- NCT02038790
- Testing
- Suboxone Sublingual Film, Zubsolv sublingual tablets
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Indivior Inc.
Coronary Arteriosclerosis
Iodine Content for Diagnostic AccuRacy and Patient Comfort For Individuals Undergoing Cardiac Computed Tomography (CT) Scanning
The purpose of the study is to evaluate diagnostic performance of high iodine (iopamidol 370 mg/dl) content versus low iodine (iodixanol 300 mg/dl) content for diagnostic accuracy by contrast-enhanced Coronary Cardiac Computed…
- Trial name
- ICARUS (NCT01052441)
- Where
- 3 sites in United States, Canada
- Volunteers
- 250 people
- Sponsor
- MDDX LLC
Contact Lens Base Curve (BC) Fit and Comfort
Evaluation of 8.5 vs 9.0 Base Curve for 1-DAY ACUVUE(r) TruEye(r) Brand Contact Lenses
The objective of this study is to determine if corneal diameter and keratometry readings correlate to subjective comfort and lens fitting characteristics.
- Trial name
- NCT02537522
- Testing
- Contact Lenses with 8.5 BC, Contact Lenses with 9.0 BC
- Where
- 2 sites in United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Contraception
FR01 and FR20 IUS (Intrauterine System) Wearing Study
The aim of the study is to evaluate two different placebo intrauterine systems, placebo FR01 and FR20 with different types of inserters, for wearing comfort, insertion/removal ease and pain compared to a placebo T-frame…
- Trial name
- NCT01595022
- Where
- 10 sites in Finland, Netherlands and 1 more
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Bayer