Clinical trials: Comfort
Corneal Staining
Comfort Evaluation of a New MPS vs. Replenish in Contact Lens Patients
To compare corneal staining after contact lens instillation with a new MPS vs. RepleniSH
- Trial name
- NCT00518700
- Testing
- new MPS, RepleniSH
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Innovative Medical
Myopia, Refractive Error
An Evaluation of Myopia Control Lenses on Wearing Experience in Myopic Children
The goal of this research study is to understand the wearing experience of A.M.L. series of lenses in myopic children. The main questions it aims to answer are: How quickly and effectively children adapt to the A.M.L.
- Trial name
- NCT07354945
- Testing
- A.M.L. Series of Lenses
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Essilor International
Normal Ocular Health
A Comparison of the Safety and Comfort of AC-170
The purpose of this study is to evaluate the safety and comfort of AC-170 compared to a placebo.
- Trial name
- NCT01495338
- Testing
- AC-170 0.17%, AC-170 0.24% (Formulation 1), AC-170 0.24% (Formulation 2)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Aciex Therapeutics, Inc.
Cystic Fibrosis
Ease of Use and Microbial Contamination of Tobramycin Inhalation Powder (TIP) Versus Nebulised Tobramycin Inhalation Solution (TIS) and Nebulised Colistimethate (COLI)
The purpose of this interventional Phase IV study was to explore the ease of use of TIP and prevalence of microbial contamination of the T-326 Inhaler compared with TIS and colistimethate administered via nebuliser for the…
- Trial name
- NCT01844778
- Testing
- Tobramycin Inhalation Powder, Tobramycin inhalation solution, Colistimethate
- Where
- 21 sites in Germany, Ireland and 3 more
- Volunteers
- 60 people
- Sponsor
- Novartis Pharmaceuticals
Vestibular Migraine, Migraine Associated Vertigo
SENSE-VM: Safety and Effectiveness of a Novel Medical Device for Symptom Ease in Vestibular Migraines
The goal of this virtual clinical trial is to compare the effectiveness of two study devices in providing temporary relief to adults aged 18-75 who suffer from symptoms of chronic Vestibular Migraines (VM), also known as Migraine…
- Trial name
- NCT06267924
- Testing
- Otoband Experimental
- Where
- United States
- Volunteers
- 322 people
- Sponsor
- Otolith Labs
Refractive Error, Myopia
Silicone Hydrogel Contact Lens Clinical and Comfort Benefits With a Multi-Purpose Disinfecting Solution
The purpose of this study was to compare lens comfort on Day 30 for Air Optix® lenses cared for with OPTI-FREE® PureMoist® (OFPM) Multi Purpose Disinfecting Solution (MPDS) compared to Acuvue® Oasys® lenses cared for with…
- Conditions
- Refractive Error, Myopia, Hyperopia, Astigmatism
- Trial name
- NCT01809197
- Testing
- Lotrafilcon B contact lenses, Senofilcon A contact lenses, OPTI-FREE PureMoist Multi-Purpose Disinfecting Solution (MPDS)
- Volunteers
- 387 people
- Sponsor
- Alcon Research
Emotion Management Skills, Lifestyle, Healthy
The Impact of Enhanced Music & Natural Visuals on Emotional Health
The investigators are conducting research on factors related to the self-regulation of mood and arousal states across a range of everyday activities as well as different levels of stress.
- Conditions
- Emotion Management Skills, Lifestyle, Healthy, Lifestyle Intervention, Recovery
- Trial name
- NCT07676110
- Testing
- soundBrilliance software application - Emotional Health
- Where
- 3 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- soundBrilliance LLC
Vaginal Delivery, Pelvic Organ Prolapse
EASE: The Materna Prep Pivotal Study
This study is designed to evaluate the safety and effectiveness of the Materna Prep Device in reducing pelvic muscle injuries during vaginal delivery.
- Trial name
- NCT03973281
- Testing
- Materna Prep Device, Standard of Care (SOC)
- Where
- 22 sites in United States
- Volunteers
- 420 people
- Sponsor
- Materna Medical
Obstructive Sleep Apnea, Sleep Apnea
The Comfort of Proactive Sleep Apnea Therapy
The goal of this clinical trial is to compare in OSA patients who regularly adhere to CPAP therapy. The main question[s] it aims to answer are: To assess if proactive therapy can effectively treat OSA with lower mean therapy…
- Trial name
- NCT06144892
- Testing
- Proactive Therapy
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- NovaResp Technologies Inc
Mitral Valve Insufficiency
EASE MITRAL Expertise-based Assessment Study on Clinical Efficacy of Profile 3D in MITRAL Valve Annuloplasty
The goal of the study is to identify the patients suffering from a mitral valve condition who benefit from the implantation of a Profile 3D annuloplasty ring in terms of acute and long-term relief of mitral valve regurgitation.
- Trial name
- NCT01112566
- Where
- 7 sites in Canada, Czechia and 3 more
- Volunteers
- 152 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Chronic Inflammation, Mobility
Effect of Maolactin™ FMR on Exercise Recovery, Inflammation and Muscle Comfort in an Otherwise Healthy Population
This is a double blind, randomised, placebo-controlled, parallel-group trial to evaluate the effect of Maolactin FMR supplementation on chronic inflammation, mobility and muscle and joint pain in an otherwise healthy population…
- Conditions
- Chronic Inflammation, Mobility, Muscle Pain, Joint Pain
- Trial name
- NCT06444763
- Testing
- Maolactin, Maltodextrin
- Where
- Australia
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- RDC Clinical Pty Ltd
Conductive Hearing Loss
Comparison of a New Bone Conduction Hearing System to a Osteo-integrated Bone Conduction Hearing Aid on a Softband
Main objectives The first main objective is to evaluate the non-inferiority of the ADHEAR system compared to the PONTO 3 SUPERPOWER softband system in terms of average tonal gain.
- Trial name
- NCT03541967
- Testing
- ADHEAR and PONTO 3 SUPER POWER on softband hearing aids
- Sponsor
- MED-EL Elektromedizinische Geräte GmbH
Myelofibrosis
Controlled Myelofibrosis Study With Oral Janus-associated Kinase (JAK) Inhibitor Treatment-II: The COMFORT-II Trial
This was an open label, randomized study comparing the efficacy and safety of randomized 2:1 Ruxolitinib tablets versus best-available therapy, as selected by the investigator.
- Trial name
- NCT00934544
- Testing
- Ruxolitinib, Best Available Therapy (BAT)
- Where
- 61 sites in Austria, Belgium and 7 more
- Volunteers
- 219 people
- Sponsor
- Novartis Pharmaceuticals
Dry Eye
Acute Comfort and Haze Profile of FID 114657
The purpose of this study is to describe the acute comfort and haze profile of FID 114657 in dry eye patients.
- Trial name
- NCT00983203
- Testing
- FID 114657 ORB Preserved Ocular Emulsion, Soothe XP Lubricant Eye Drops
- Volunteers
- 20 people
- Sponsor
- Alcon Research
Inflammation, Burns
Open Multi-centre Investigation to Evaluate Signs and Symptoms of Local Inflammation/Infection on Chronic Ulcers and Partial Thickness Burns When Using Mepilex Border Ag as an Anti-microbial Wound Dressing
The purpose of this study is to evaluate the change in signs of inflammation/local infection when Mepilex Border Ag is used in normal clinical practice when used on chronic ulcers (venous leg, diabetic foot and pressure ulcers)…
- Conditions
- Inflammation, Burns, Ulcers
- Trial name
- NCT01214811
- Testing
- Mepilex Border Ag
- Where
- 3 sites in United States
- Volunteers
- 27 people
- Sponsor
- Molnlycke Health Care AB
Pressure Ulcers
A Pilot Study of the Envision® Surface
This study is to evaluate the clinical safety and effectiveness of the Envision® surface.
- Trial name
- NCT00405834
- Testing
- Envision® Patient Support System
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Hill-Rom
Digestion, Happiness
Parental Notions and Clinical Experiences About Child's Gut Comfort, Overall Satisfaction and Sense of Well-being When Consuming a New Toddler Milk
This is a prospective, open-label, single-arm study in a real-world setting of healthy Chinese toddlers provided with new toddler milk for a total of 4 weeks (28 days).
- Conditions
- Digestion, Happiness, Temperament
- Trial name
- NCT04768933
- Testing
- Toddler Milk
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Arrhythmias, Cardiac
"EASE" Epicardial Access With the EpiAccess System
Prospective non-randomized, single arm trial to further evaluate the safety and performance of EpiAccess, the study device, for gaining access to the normal, non-distended pericardial space during epicardial diagnostic or…
- Trial name
- EASE2 (NCT02209064)
- Testing
- Pericardial access
- Where
- Czechia
- Volunteers
- 25 people
- Sponsor
- EpiEP, Inc.
Dyskinesia, Levodopa Induced Dyskinesia (LID)
ADS-5102 for the Treatment of Levodopa Induced Dyskinesia (EASE LID Study)
This is a multi-center, randomized, double-blind, placebo-controlled, 2-arm, parallel group study to evaluate the efficacy and safety of ADS-5102 extended release (ER) capsules, an investigational formulation of amantadine, dosed…
- Conditions
- Dyskinesia, Levodopa Induced Dyskinesia (LID), Parkinson's Disease
- Trial name
- EASE LID (NCT02136914)
- Testing
- ADS-5102
- Where
- 46 sites in United States, Canada
- Volunteers
- 126 people
- Sponsor
- Adamas Pharmaceuticals, Inc.
Running Comfort, Running Speed
Orthotics and Running
To investigate whether a prefabricated Orthotic inserted into running shoes will increase comfort, decrease injury and improve speed during recreational running as compared to running shoes without the prefabricated Orthotic.
- Conditions
- Running Comfort, Running Speed, Occurence of Running Related Injuries
- Trial name
- NCT04901442
- Testing
- Aetrex L700 Speed orthotic
- Where
- United Kingdom
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Talita Cumi Ltd.