Clinical trials: Comfort
Chronic Obstructive Pulmonary Disease (COPD)
Study Evaluating Preference, Satisfaction and Ease of Use of Inhalers in Chronic Obstructive Pulmonary Disease (COPD) Diagnosed Patients
Preference study: Genuair vs HandiHaler inhalers in COPD patients.
- Trial name
- NCT01385696
- Testing
- Genuair® (Almirall S.A.), HandiHaler® (Boehringer Ingelheim's)
- Where
- 4 sites in Germany, Netherlands
- Volunteers
- 130 people
- Sponsor
- Almirall, S.A.
Vision Correction
Performance of Two Silicone Hydrogel Toric Contact Lenses
Evaluation of the clinical performance of two toric contact lenses in a 2-week, single masked (subject), daily wear, randomized, bilateral, parallel group study.
- Trial name
- NCT00638846
- Testing
- senofilcon A toric, balafilcon A toric
- Where
- 19 sites in United States
- Volunteers
- 276 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Bladder Dysfunction, Urinary Retention
Patient-operated Valved Catheter Versus Indwelling Transurethral Catheter
Following surgery for female urinary incontinence and/or pelvic organ prolapse, women are sometimes temporarily unable to empty their bladders and are sent home with a transurethral indwelling catheter attached to a bag which…
- Trial name
- NCT01460303
- Testing
- Bladder catheter: OPTION-vf patient controlled catheter vs. indwelling transurethral catheter with leg bag, Transurethral catheter with leg bag
- Volunteers
- 49 people
- Sponsor
- University of Massachusetts, Worcester
Refractive Error
Ocular Comfort and the "Aging" Lens (ERBIUM)
The purpose of this trial was to evaluate the factors affecting comfortable contact lens wear and how those factors affect contact lens replacement frequency.
- Trial name
- NCT01198600
- Testing
- Habitual contact lens, Lotrafilcon B contact lens, Contact lens cleaning and disinfecting system (ClearCare)
- Where
- Canada
- Volunteers
- 78 people
- Sponsor
- CIBA VISION
Renal Stone, Nephrolithiasis
Impact Ureteral Sheath Design During Ureteroscopy
The purpose of this study is to assess whether one of two ureteral access sheaths is safer for patients undergoing ureteroscopy. Both sheaths are FDA approved devices and commercially available.
- Conditions
- Renal Stone, Nephrolithiasis, Urolithiasis
- Trial name
- NCT03349099
- Testing
- Cook Flexor, Boston Scientific Navigator
- Volunteers
- 95 people
- Sponsor
- The Cleveland Clinic
Visual Acuity, Comfort
Senofilcon A Investigational Manufacturing Process
To evaluate the impact of a new contact lens hydration process
- Conditions
- Visual Acuity, Comfort, Overall Vision
- Trial name
- NCT01951703
- Testing
- senofilcon A
- Where
- 4 sites in United States
- Volunteers
- 136 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
Evaluation of Comfilcon A and Senofilcon A Lenses
Evaluation of Comfilcon A and Senofilcon A Lenses
- Trial name
- NCT01695369
- Testing
- Senofilcon A; Comfilcon A, Comfilcon A; Senofilcon A
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- CooperVision, Inc.
Sleep Apnea
Modified AutoSet Device vs Existing AutoSet Device, the Assessment of Efficacy and Subjective Comfort of the Treatment.
The purpose of this study is to determine if the performance of the modified AutoSet device is equivalent or better than the existing AutoSet device (VPAP Auto) in the efficacy of the treatment and the subjective comfort.
- Trial name
- NCT00906958
- Testing
- Nexus Flow Generator, VPAP Flow Generator 25
- Where
- Australia
- Volunteers
- 20 people
- Sponsor
- ResMed
Gonarthrosis
Validation of a Knee Brace for Gonarthrosis
A study about the effects of different fastening systems for knee braces on comfort, ease of installation and treatment efficacy both physical and psychological.
- Trial name
- NCT05814471
- Testing
- Cable fastening system and 3d printed straps(14 days), Velcro straps system(14 days), Adjustment period(Velcro-14 days)
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- TOPMED
Coronary Artery Disease, Aortic Valve Disorder
Carpentier-Edwards PERIMOUNT Magna Ease Pericardial Bioprosthesis, Model 3300TFX
The purpose of the study is to demonstrate the long term safety and effectiveness of the Carpentier-Edwards PERIMOUNT Magna Ease Valves in patients undergoing aortic valve replacement with or without concomitant procedures…
- Conditions
- Coronary Artery Disease, Aortic Valve Disorder, Heart Failure, Aortic Valve Stenosis
- Trial name
- NCT01171625
- Testing
- Implantation of CEP Magna Ease Model 3300TFX
- Where
- 13 sites in United States, Austria and 4 more
- Volunteers
- 283 people
- Sponsor
- Edwards Lifesciences
Arthritis, Gout
Phone-Based Based Walk With Ease Program for Adults With Arthritis
The objective of this study is to examine the short-term (6-weeks and 6 months) and long-term (1 year) effects of a phone-based version of Walk With Ease intervention.
- Conditions
- Arthritis, Gout, Fibromyalgia, Rheumatoid Arthritis
- Trial name
- NCT05289544
- Testing
- Phone-Based Walk With Ease
- Where
- United States
- Volunteers
- 267 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Breast Cancer
Evaluating Image Quality and Comfort of an Investigational Curved Paddle Compared to a Standard Paddle
The goal of this study is to evaluate patient comfort during compression with a standard flat mammographic paddle and an investigational curved paddle.
- Trial name
- NCT03611543
- Testing
- Standard of Care Flat Paddle, Investigational Curved Paddle
- Where
- 4 sites in United States
- Volunteers
- 443 people, healthy volunteers welcome
- Sponsor
- Hologic, Inc.
Myopia
A Prospective Study of Two Daily Disposable Contact Lenses
The purpose of this study was to evaluate the performance of a novel silicone hydrogel contact lens, DAILIES TOTAL1® (DT1) compared to the standard hydrogel material in 1-DAY ACUVUE® MOIST® (1DAVM) contact lens in contact lens…
- Trial name
- NCT01636986
- Testing
- Delefilcon A contact lenses, Etafilcon A contact lenses
- Volunteers
- 62 people
- Sponsor
- Alcon Research
Dry Eye
Digital Device Users Who Are Treated With Systane Hydration PF
Systane Hydration PF is a recently released preservative-free artificial tear that is able to supplement the ocular surface's moisture while simultaneously soothing the eye.
- Trial name
- NCT04837807
- Testing
- Systane Hydration PF
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Dry Eye
Acute Comfort of Lubricant Eye Drop FID 111421
To evaluate the acute comfort and blurring profile between two artificial tears products in dry eye patients
- Trial name
- NCT00673959
- Testing
- Lubricant Eye Drop FID 111421, Optive Lubricant Eye Drop
- Volunteers
- 20 people
- Sponsor
- Alcon Research
Corneal Staining
Short-Term Evaluation of Corneal Staining With Balafilcon A Lenses and Two Multi-Purpose Solutions
An investigational multi-purpose solution (MPS)was clinically evaluated against Biotrue MPS at specific time points over the course of four days. The study was conducted with PureVision lenses.
- Trial name
- NCT01240122
- Testing
- Biotrue MPS, Investigational MPS
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Multiple Sclerosis
The Multicenter, Open-label, Single-use Autoinjector Convenience Study
The purpose of this trial is to test the Single-Use Autoinjector for a) ease of use; b) multiple domains related to subject's acceptability and satisfaction, and c) reliability of the correct function for self-injection of Rebif®…
- Trial name
- NCT00958009
- Testing
- Rebidose®
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- EMD Serono
Chronic Kidney Diseases
everlinQ Endovascular Access System Enhancements (EASE) Study
Prospective, single-center study to evaluate the everlinQ System when used to create an endoAVF in hemodialysis patients.
- Trial name
- NCT03708770
- Testing
- everlinQ endoAVF System
- Volunteers
- 32 people
- Sponsor
- C. R. Bard
Dry Eye
Efficacy, Tolerability, and Comfort of 0.3% Hypromellose Eyedrops in Patients Undergoing LASIK Surgery
This study is designed to assess the tolerability and comfort of peri-operative 0.3% hypromellose eye drops in LASIK surgery patients and to assess whether pre-operative 0.3% hypromellose eye drops add to post-operative comfort…
- Trial name
- NCT00909324
- Testing
- Pre-LASIK 0.3% hypromellose, Post-LASIK 0.3% hypromellose
- Where
- India
- Volunteers
- 170 people
- Sponsor
- Novartis Pharmaceuticals
Obesity
Early Anatomy Scan for Evaluation of Obese Pregnant Women (EASE-O)
The purpose of this study is to assess the feasibility of ultrasound in the first trimester, assess the completion rate of ultrasounds for fetal anatomy in the first trimester compared to completion rates of ultrasounds for fetal…
- Trial name
- NCT04639973
- Testing
- Group 1 (First trimester ultrasound), Group 2 (Second trimester anatomy ultrasound)
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- The University of Texas Health Science Center, Houston