Clinical trials: Comfort
Pain
Vapocoolant (Pain Ease Medium Stream) for Intravenous Lines in Emergency Department Patients
To determine the efficacy and safety of vapocoolant stream (Pain Ease Medium Stream ) in decreasing the pain of intravenous cannulation. To compare vapocoolant stream (Pain Ease medium Stream) with control (e.g.
- Trial name
- NCT01670487
- Testing
- Vapocoolant, Sterile water
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- The Cleveland Clinic
Contact Lens Comfort
Contact Lens Adaptation in Neophytes
Eye care professionals prescribe contact lenses to new wearers on a daily basis, and it is common practice for practitioners to educate their patients to gradually increase their contact lens wear time over their first few days…
- Trial name
- CLAN (NCT02148263)
- Testing
- senofilcon A
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Myelofibrosis
Controlled Myelofibrosis Study With Oral Janus-associated Kinase (JAK) Inhibitor Treatment-II: The COMFORT-II Trial
This was an open label, randomized study comparing the efficacy and safety of randomized 2:1 Ruxolitinib tablets versus best-available therapy, as selected by the investigator.
- Trial name
- NCT00934544
- Testing
- Ruxolitinib, Best Available Therapy (BAT)
- Where
- 61 sites in Austria, Belgium and 7 more
- Volunteers
- 219 people
- Sponsor
- Novartis Pharmaceuticals
Visual Analog Pain Scale
Vapocoolant Spray's Role in Reducing Pain During Capillary Glucose Testing
Capillary blood glucose measurement is a routine procedure in emergency departments, but it may cause pain and discomfort because it requires fingertip puncture.
- Trial name
- NCT06789055
- Testing
- Vapocoolant Spray
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Abant Izzet Baysal University
Visual Acuity
Evaluation of Comfort for Two Marketed Daily Disposable Contact Lenses
This study is a 2-phase adaptive approach utilizing a 2×2 crossover design. The study lenses will be worn in a bilateral fashion for a period of approximately 1-week each.
- Trial name
- NCT04968925
- Testing
- ACUVUE Oasys 1-Day, Precision 1
- Where
- 10 sites in United States
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Ametropia
Evaluation of Disinfecting Solutions and Protein Remover With a Silicone Hydrogel Lens
The purpose of this study is to determine if reduced lens deposits and increased comfort can be achieved by using Multipurpose disinfecting solutions (MPDS) in a no-rub format but in conjunction with an intensive cleaner, rather…
- Trial name
- NCT00754338
- Testing
- Alcon Opti-Free® RepleniSH® with Supraclens®, Alcon Opti-Free® RepleniSH®, B&L ReNu MultiPlus™
- Where
- Canada
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Pain, Procedural
The Effect of Local Anesthesia on Control of Intraoperative Physiologic Parameters and Post Operative Comfort
The purpose of this study is to compare patient responses during and after surgery when local anesthetic is used for dental treatment under general anesthesia (GA) and when it is not used.
- Trial name
- NCT04500158
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Virginia Commonwealth University
Bladder Dysfunction, Urinary Retention
Patient-operated Valved Catheter Versus Indwelling Transurethral Catheter
Following surgery for female urinary incontinence and/or pelvic organ prolapse, women are sometimes temporarily unable to empty their bladders and are sent home with a transurethral indwelling catheter attached to a bag which…
- Trial name
- NCT01460303
- Testing
- Bladder catheter: OPTION-vf patient controlled catheter vs. indwelling transurethral catheter with leg bag, Transurethral catheter with leg bag
- Volunteers
- 49 people
- Sponsor
- University of Massachusetts, Worcester
Deep Vein Thrombosis, Venous Thrombosis
A Preliminary Clinical Usability Study for the Recovery Force DVT II Cuff
A preliminary clinical usability study to assess design, comfort, wearability, and acceptance of Recovery Force's Deep vein thrombosis (DVT) cuff
- Trial name
- NCT03328624
- Testing
- Deep Vein Thrombosis (DVT) Cuff
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Varicose Veins
COMFORT: A Multicenter, Open-label, Randomized, Crossover Study
The purpose of this study is to evaluate pain the patient experienced following treatment of varicose veins with Varithena® compared to radiofrequency ablation.
- Trial name
- COMFORT (NCT02462720)
- Testing
- Varithena®, Radiofrequency ablation
- Where
- 4 sites in United States
- Volunteers
- 35 people
- Sponsor
- Boston Scientific Corporation
Chronic Sinus Disease, Surgery
Efficacy of PuraSinus Versus Bioresorbable Nasal Dressings
Postoperative care of patients undergoing endoscopic sinus surgery (ESS) is important both to minimize discomfort for the patients and to obtain the optimal long-term outcomes.
- Trial name
- NCT04970966
- Testing
- PuraSinus, Bioresorbable Nasal Dressing
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Pulmonary Disease, Chronic Obstructive
Ease of Use and Correct Use Study of Placebo ELLIPTA® Inhaler in COPD Subjects
Chronic obstructive pulmonary disease (COPD) is a preventable and treatable disease characterized by airflow limitation that is not fully reversible.
- Trial name
- NCT02586493
- Testing
- Questionnaire
- Where
- 16 sites in United States
- Volunteers
- 278 people
- Sponsor
- GlaxoSmithKline
Astigmatism
In-office Evaluation of Two Toric Soft Contact Lenses and a Spherical Soft Contact Lens
The purpose of this study is to determine the relative performance of a new toric soft contact lens against a toric and a spherical contact lens currently available in market, specifically with regards to the fit and visual…
- Trial name
- NCT00584727
- Testing
- senofilcon A toric contact lens, alphafilcon A toric, etafilcon A sphere
- Volunteers
- 96 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Astigmatism
Toric Contact Lens Digital Performance and Comfort Study
This study seeks to quantify digital visual performance and subjective visual acceptance of toric contact lenses as compared to spherical lenses in low to moderate astigmatic patients.
- Trial name
- NCT04772560
- Testing
- Precision1 for Astigmatism, Precision1 Sphere
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Kathryn Richdale
Substance Use Disorders
Using Aromatherapy in Substance Use Disorder
The purpose of this clinical trial study is to see if Bergamot, an aroma therapy essential oil, has any effect on comfort, ease, and stress.
- Trial name
- NCT05660434
- Testing
- Aroma Inhaler with Bergamot essential oil
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- West Virginia University
Coronary Artery Disease, Mitral Valve Regurgitation
Magna® Mitral Pericardial Bioprostheses Post-Approval Study Protocol
The purpose of the study is to demonstrate the long term safety and effectiveness of the Carpentier-Edwards® PERIMOUNT Magna Mitral Valves in patients undergoing mitral valve replacement with or without concomitant procedures…
- Conditions
- Coronary Artery Disease, Mitral Valve Regurgitation, Mitral Valve Incompetence, Heart Failure
- Trial name
- NCT00853632
- Testing
- CEP MAGNA MITRAL PERICARDIAL BIOPROSTHESES
- Where
- 15 sites in United States, Austria and 2 more
- Volunteers
- 329 people
- Sponsor
- Edwards Lifesciences
Myopia, Hyperopia
Evaluation of the Effectiveness of Two Marketed Multi-Purpose Solutions for Silicone Hydrogel Contact Lenses - Study 2
The purpose of this study was to evaluate the performance of Opti-Free® PureMoist® Multi-purpose Disinfecting Solution (MPDS) compared to AMO RevitaLens OcuTec® MPDS (US brand name)/COMPLETE RevitaLens (Europe brand name) in…
- Conditions
- Myopia, Hyperopia, Contact Lens Comfort
- Trial name
- NCT01684046
- Testing
- Opti-Free® PureMoist® MPDS, RevitaLens MPDS, Habitual Contact Lenses
- Volunteers
- 196 people
- Sponsor
- Alcon Research
Breast Cancer
Evaluating Image Quality and Comfort of an Investigational Curved Paddle Compared to a Standard Paddle
The goal of this study is to evaluate patient comfort during compression with a standard flat mammographic paddle and an investigational curved paddle.
- Trial name
- NCT03611543
- Testing
- Standard of Care Flat Paddle, Investigational Curved Paddle
- Where
- 4 sites in United States
- Volunteers
- 443 people, healthy volunteers welcome
- Sponsor
- Hologic, Inc.
Open-Angle Glaucoma, Ocular Hypertension
A Single Dose Comfort Comparison of Travatan Z in One Eye Versus Xalatan in the Opposite Eye in Patients With Primary Open-Angle Glaucoma or Ocular Hypertension
The purpose of this study is to compare the comfort of Travatan Z in one eye and Xalatan in the opposite eye in patients with primary open-angle glaucoma or ocular hypertension.
- Trial name
- NCT00527592
- Testing
- Travoprost ophthalmic solution 0.004% with SofZia® preservative system (TRAVATAN Z®), Latanoprost ophthalmic solution 0.005% (XALATAN®)
- Volunteers
- 54 people
- Sponsor
- Alcon Research
Diabetic Foot Ulcers
Evaluating the Ease of Use of a VAC GranuFoam Bridge Dressing on Diabetic Foot Ulcers Receiving VAC Negative Pressure Wound Therapy
The study is aimed at evaluating the clinician's perceived ease of using the V.A.C. GranuForm bride dressing and the patients perceived level of comfort during the dressing wear.
- Trial name
- NCT00847730
- Testing
- V.A.C. Negative Pressure Wound Therapy System
- Where
- 6 sites in United States
- Volunteers
- 33 people
- Sponsor
- KCI USA, Inc