Clinical trials: Common Bile Duct Diseases
Common Bile Duct Calculi
Application and Translational Research of 3D Printed in Treatment of Choledocholithiasis Under ERCP
The goal of this clinical trial is to learn about Application and translational research of 3D printed models in the surgical treatment of common bile duct stones under endoscopic retrograde cholangiopancreatography.
- Trial name
- NCT06071247
- Testing
- 3D printed models
- Volunteers
- 60 people
- Sponsor
- Jiawei Qin
Choledocholithiasis
Application of Machine Learning Models to Reduce Need for Diagnostic EUS or MRCP in Patients With Intermediate Likelihood of Choledocholithiasis
Machine learning predictive model can help in stratifying heterogenous intermediate likelihood group to reduce need for EUS or MRCP in selected subgroup of patients.
- Trial name
- NCT06066372
- Where
- India
- Volunteers
- 1,000 people
- Sponsor
- Asian Institute of Gastroenterology, India
Common Bile Duct Gall Stones, Infection
Fibrin Sealant for Cholangiotomy Closure Study
Bile leak reduction from the common bile duct, as a result of glue appliance after cholangiotomy.
- Conditions
- Common Bile Duct Gall Stones, Infection, Bile Leak
- Trial name
- NCT02545153
- Testing
- Tisseel, Baxter (Aprotinin and Fibrinogen), Control
- Where
- Sweden
- Volunteers
- 200 people
- Sponsor
- Lasarettet i Enköping
Choledocholithiasis, Higher Risk Patients
Study Investigating the Best Method of Treatment of Bile Duct Stones in Higher Risk Patients
The aim of the trial is to compare two operations which are used to treat bile duct stones. The hypothesis of the study is that there is no difference between endoscopic sphincterotomy followed by laparoscopic cholecystectomy or…
- Trial name
- NCT00612846
- Testing
- Endoscopic sphincterotomy and subsequent laparoscopic cholecystectomy, Laparoscopic bile duct exploration during cholecystectomy
- Volunteers
- 91 people
- Sponsor
- North Bristol NHS Trust
Acute Biliary Pancreatitis
Early EUS in Acute Biliary Pancreatitis
Acute biliary pancreatitis (ABP) is a potentially life-threatening condition caused by common bile duct (CBD) stones or sludge, which requires prompt diagnosis and treatment by endoscopic removal of the material.
- Trial name
- NCT02430285
- Testing
- Endoscopic Ultrasound, Olympus 180 series echoendoscope
- Where
- Italy
- Volunteers
- 181 people
- Sponsor
- Istituto Clinico Humanitas
Common Bile Duct Diseases, Common Bile Duct Calculi
Effects of Dexamethasone on Common Bile Duct Cannulation Time
The main aim of this clinical trial is to evaluate the effects of dexamethasone on common bile duct cannulation time during endoscopic retrograde cholangiopancreatography (ERCP) in patients with biliary pathologies.
- Conditions
- Common Bile Duct Diseases, Common Bile Duct Calculi, Common Bile Duct Stricture, Common Bile Duct Neoplasms
- Trial name
- NCT05945797
- Testing
- Dexamethasone 4mg
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Gujranwala medical college District Headquarters Hospital, Gujranwala
Biliary Disease, Pancreatic Diseases
Influence of the Endoscopists and Endoscopic Retrograde CholangioPanceratography
Retrospective analysis on a prospective database that analyzes the influence of the number of endoscopists on the Endoscopic Retrograde CholangioPanceratography result.
- Trial name
- NCT04705740
- Testing
- ERCP
- Where
- Spain
- Volunteers
- 2,561 people
- Sponsor
- Fundacion Miguel Servet
Pancreatic Cancer, Common Bile Duct Diseases
A Prospective Study on the Safety and Efficacy of Robot-assisted Pancreaticoduodenectomy
Further studies are needed to investigate the prognosis and perioperative safety of patients undergoing robotic-assisted pancreaticoduodenectomy.
- Conditions
- Pancreatic Cancer, Common Bile Duct Diseases, Periampullary Carcinoma
- Trial name
- NCT05755594
- Testing
- Robot-assisted Pancreaticoduodenectomy
- Volunteers
- 100 people
- Sponsor
- The First Affiliated Hospital of University of South China
Irritable Bowel Syndrome, Gallstone Disease
Pharmacokinetics, Bioequivalence, and Safety Study of Trimedat® 76,95 mg Orally Disintegrating Tablets and Trimedat® 100 mg Tablets in Healthy Volunteers.
This study aims to evaluate pharmacokinetic profile, safety and establish bioequivalence of the investigational drug Trimedat® 76,95 mg orally disintegrating tablets compared to the reference drug Trimedat® 100 mg tablets in…
- Conditions
- Irritable Bowel Syndrome, Gallstone Disease, GERD, Biliary Dyskinesia
- Trial name
- NCT07421011
- Testing
- Trimedat®
- Where
- Russia
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Valenta Pharm JSC
Choledocholithiasis, Cholangiocarcinoma
Etomidate vs. Midazolam for Sedation During ERCP
Recently up-coming drug, etomidate which is a modulator of GABA(gamma-Aminobutyric acid)-A receptor has been known that it maintains the appropriate sedative levels and affects little effects on respiratory system.
- Conditions
- Choledocholithiasis, Cholangiocarcinoma, Pancreatitis, Pancreatic Cancer
- Trial name
- NCT02027311
- Testing
- Etomidate, Midazolam, Meperidine
- Where
- South Korea
- Volunteers
- 63 people
- Sponsor
- Cheju Halla General Hospital
Cholelithiasis, Choledocholithiasis
Microbiomes in Patients of Recurrent Common Bile Duct Stones
Bile duct stones is a common biliary tract disease, which is characterized by high morbidity and frequent recurrence. Endoscopic retrograde cholangiopancreatography (ERCP) is an effective therapy for common bile duct stones, and…
- Trial name
- NCT03102281
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The Second Hospital of Nanjing Medical University
Common Bile Duct Calculi
Modified Continuous Versus Interrupted Choledochotomy Closure in LCBDE With T-Tube Drainage
This observational study aims to compare two techniques for closing the common bile duct incision (choledochotomy) after laparoscopic common bile duct exploration (LCBDE) with T-tube drainage.
- Trial name
- NCT07345663
- Testing
- Modified continuous suture, Interrupted suture
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Yantai Affiliated Hospital of Binzhou Medical University
Sphincter of Oddi Function
Endoclip Papillaplasty Recover Sphincter of Oddi Function After Endoscopic Sphincterotomy for Bile Duct Gallstones
Gallstones in the common bile duct (CBD) may be asymptomatic but may lead to complications such as acute cholangitis or acute pancreatitis. EST is widely used for the treatment of bile duct gallstones.
- Trial name
- NCT04183036
- Testing
- Endoclip papillaplasty
- Where
- China
- Volunteers
- 14 people
- Sponsor
- Peking University Third Hospital
Common Bile Duct Calculi
Failed Retrograde Cholangiopancreatography (ERCP) Stone Extraction: Surgical Interference
Assessment of the differences in stone size and the largest CBD diameter before and after stenting in one or two sessions. Stone clearance and complications were also determined with the ERCP, and factors associated with complete…
- Trial name
- NCT05746832
- Testing
- Endoscopic stenting Retrograde Cholangiopancreatography (ERCP)
- Where
- Egypt
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Assiut University
Choledocholithiasis, Asymptomatic Condition
The Treatment Effect for Asymptomatic Common Bile Duct Stone
This study is prospective, multicenter study for identify the characteristics of asymptomatic common bile duct stones and effectiveness of treatment.
- Conditions
- Choledocholithiasis, Asymptomatic Condition, Quality of Life
- Trial name
- NCT06215040
- Testing
- Endoscopic retrograde cholangiopancratography
- Where
- South Korea
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Kyungpook National University Hospital
Bile Duct Stricture, Choledocholithiasis
Prospective Study to Investigate the Frequency of Possible Bacterial Entry Into the Bloodstream (Bacteremia) and Infectious Complications Associated With the Use of the Spyglass Cholangioscopy System During ERCP (Endoscopic Retrograde Cholangiopancreatography).
The aim of this study is to prospectively evaluate the frequency of bacteremia after ERCP/cholangioscopy using the Spyglass Direct Visualization System.
- Trial name
- NCT01414400
- Testing
- Blood draw for culture
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Stanford University
Pancreaticobiliary Maljunction
Clinical Correlation Study Between Anomalous Pancreaticobiliary Ductal Junction and Malignant Tumors of the Biliary System and the Establishment of an AI-based Automated Recognition System
To explore the occurrence of pancreaticobiliary maljunction (PBM) in the Chinese population, the characteristics of various subtypes, and the relationship between PBM and malignant tumors of the biliary system.
- Trial name
- NCT06903520
- Where
- China
- Volunteers
- 2,439 people
- Sponsor
- Chinese PLA General Hospital
Bile Duct Diseases
Efficacy of Double Wire Technique in Difficult Cases of Common Bile Duct Cannulation in ERCP (UDOGUIA-04)
The purpose of this study is to determine if the double guide wire technique is more effective than the conventional method in those cases of difficult selective biliary cannulation in the ERCP procedures.
- Trial name
- NCT00270868
- Testing
- Double guide wire technique, Standard bile duct cannulation
- Where
- 6 sites in Spain
- Volunteers
- 1,050 people
- Sponsor
- Puerta de Hierro University Hospital