Clinical trials: Common Bile Duct Diseases
Choledocholithiasis, Bile Duct Cancer
Loop-tipped Guidewire in Selective Biliary Cannulation
1. Background Advanced guidewires with a U-shaped tip could effectively cross the long or multi-occlusive segment smoothly and go into the distal outflow vessel.
- Conditions
- Choledocholithiasis, Bile Duct Cancer, Pancreatic Cancer, Ampullary Tumor
- Trial name
- NCT02028845
- Testing
- Biliary cannulation with loop guidewire, Biliary cannulation with straight guidewire
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Ajou University School of Medicine
Biliary Disease
Common Bile Duct Pressures in Patients With and Without Cholelithiasis
Objective. To measure the pressures of the common bile duct in patients with and without cholelithiasis and relating them to the presence of pancreatobiliary reflux. Summary Background Data.
- Trial name
- NCT04025645
- Testing
- MEASUREMENT OF COMMON BILE DUCT PRESSURES
- Volunteers
- 87 people
- Sponsor
- Hospital de La Serena
Sphincter of Oddi Dysfunction
Evaluating Predictors & Interventions in Sphincter of Oddi Dysfunction
The Evaluating Predictors \& Interventions in Sphincter of Oddi Dysfunction(SOD) study (EPISOD) is a randomized sham-controlled study of biliary and pancreatic sphincterotomy as treatment for patients with pain after…
- Trial name
- EPISOD (NCT00688662)
- Testing
- ERCP with sphincterotomy, ERCP without sphincterotomy
- Where
- 7 sites in United States
- Volunteers
- 214 people
- Sponsor
- Medical University of South Carolina
Choleclithiasis, Common Bile Duct Stones
Randomized Trial of ERCP Then Laparoscopic Cholecystectomy vs. Laparoscopic Cholecystectomy Plus Laparoscopic Common Bile Duct Exploration in Patients With Likely Choledocholithiasis
Objective: We compared outcome parameters for good-risk patients with classic signs, symptoms, laboratory and abdominal imaging features of cholecystolithiasis and choledocholithiasis randomized to either LC + LCBDE or ERCP/S +…
- Trial name
- ERCP/CBDE (NCT00807729)
- Testing
- ERCP, LapCBDE
- Where
- United States
- Volunteers
- 122 people
- Sponsor
- University of California, San Francisco
Gall Stones, Common Bile Duct
Fluorescent Cholangiography and Bile Duct Stones
Background. X-ray cholangiography has a high sensitivity and specificity of detecting bile duct stones and is the gold standard.
- Trial name
- NCT03530241
- Testing
- Presence of bile duct stones, Non-presence of bile duct stones
- Where
- Denmark
- Sponsor
- Hvidovre University Hospital
Pancreatic Cancer, Cholangiocarcinoma of the Extrahepatic Bile Duct
EUS Evaluation of CBD Diameter in Malignant Obstructive Jaundice
The main objective of the study is to evaluate the size of the common bile duct (CBD) in a large cohort of patients with jaundice secondary to pancreatic head or distal bile duct malignancy undergoing diagnostic EUS for tissue…
- Conditions
- Pancreatic Cancer, Cholangiocarcinoma of the Extrahepatic Bile Duct, Ampulla of Vater Cancer, Jaundice, Obstructive
- Trial name
- ECCO (NCT03494023)
- Testing
- Endoscopic ultrasound
- Where
- Romania
- Volunteers
- 539 people
- Sponsor
- Clinical Hospital Colentina
Cholelithiasis, Cholecystitis
Transvaginal Cholecystectomy Using Endoscopic Assistance
Surgical removal of the gallbladder is needed in 1 million people per year in the USA. The procedure is done by placing four tubes (cannula) from 5 to 10 mm through the abdominal wall.
- Conditions
- Cholelithiasis, Cholecystitis, Biliary Dyskinesia
- Trial name
- NCT00815438
- Testing
- cholecystectomy.
- Sponsor
- University of Missouri-Columbia
Obstructive Jaundice, Biliary Stricture
Evaluation of the Use of a Biodegradable Endoprothesis in the Prevention of Post-Endoscopic Retrograde CholoangioPancreatography Pancreatitis
The use of an endoprothesis in a pancreatic duct is a measure to minimize the incidence and severity of Post-Endoscopic Retrograde CholoangioPancreatography Pancreatitis.
- Conditions
- Obstructive Jaundice, Biliary Stricture, Sphincter of Oddi Dysfunction
- Trial name
- ARCHIMEDE (NCT03977779)
- Testing
- Placement of ARCHIMEDES fast biodegradable stent during the Endoscopic Retrograde CholoangioPancreatography
- Where
- 2 sites in France
- Volunteers
- 46 people
- Sponsor
- Institut Paoli-Calmettes
Sphincter of Oddi Dysfunction
Pinaverium Bromide in Post-cholecystectomy Sphincter of Oddi Dysfunction
Sphincter of Oddi dysfunction (SOD) refers to biliary kinetic abnormality of the sphincter of Oddi (SO), often accompanied by pain, hepatic and pancreatic enzyme elevation, common bile duct (CBD) dilation or onset of…
- Trial name
- NCT02833103
- Testing
- Danshu Capsules, Pinaverium Bromide
- Where
- China
- Volunteers
- 168 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Common Bile Duct Calculi, Laparoscopic Abdominal Surgery
Safety and Feasibility of Early T-tube Cholangiography Performed Within 2 to 3 Days After Laparoscopic Common Bile Duct Exploration
Current clinical evidence indicates that 10-20% of patients with symptomatic cholelithiasis present with concomitant common bile duct stones (CBDS), a clinical scenario requiring tailored therapeutic approaches.
- Conditions
- Common Bile Duct Calculi, Laparoscopic Abdominal Surgery, Cholangiography
- Trial name
- LCBDE (NCT07058740)
- Testing
- early cholangiography
- Where
- China
- Volunteers
- 265 people
- Sponsor
- Piyou Ji
Choledocholithiasis, Cholecystolithiasis
One-stage and Delayed Laparoscopic Cholecystectomy After Endoscopic Retrograde Cholangiopancreatography with Endoscopic Sphincterotomy in Cholecystocholedocholithiasis
In this study, it is planned to compare ERCP with ES + delayed LC in children, with one-stage LC + ERCP with ES in adults to confirm that ERCP with ES + delayed LC is more suitable for pediatric patients with…
- Conditions
- Choledocholithiasis, Cholecystolithiasis, Cholangiopancreatography, Endoscopic Retrograde, Laparoscopic Cholecystectomy
- Trial name
- NCT06676241
- Testing
- endoscopic retrograde cholangiopancreatography; laparoscopic cholecystectomy, endoscopic retrograde cholangiopancreatography;laparoscopic cholecystectomy
- Where
- Russia
- Volunteers
- 44 people
- Sponsor
- Moscow Regional Research and Clinical Institute (MONIKI)
Choledocholithiasis, Cholecystolithiasis
ERCP and LC for Cholecystocholedocholithiasis in Children: Should It Be Accomplished in One or Repeated Hospitalization?
Chronic calculous cholecystitis in pediatric patients leads to choledocholithiasis in about 12% of cases. These patients require removal of stones from the common bile duct.
- Conditions
- Choledocholithiasis, Cholecystolithiasis, Cholangiopancreatography, Endoscopic Retrograde, Laparoscopic Cholecystectomy in Children
- Trial name
- NCT06672991
- Testing
- Endoscopic retrograde cholangiopancreatography;laparoscopic cholecystectomy
- Where
- Russia
- Volunteers
- 25 people
- Sponsor
- Moscow Regional Research and Clinical Institute (MONIKI)
Choledocholithiasis, Cholangiopancreatography, Endoscopic Retrograde
Effect of the Sequence of Dilatation and Lithotripsy on the Treatment of Choledocholithiasis With ERCP
Choledocholithiasis is a common and frequently occurring disease in China, accounting for 15.3% ~ 31.7% of the total cholelithiasis.According to its source, can be divided into primary and secondary choledocholithiasis.For large…
- Trial name
- NCT05035433
- Testing
- First lithotripsy and then EPBD, First EPBD and then lithotripsy
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Acute Cholangitis, Biliary Tract Infection
Comparative Efficacy Of Intraductal Antibiotic During ERCP In Acute Cholangitis
Does intraductal administration of antibiotics during endoscopic retrograde cholangiopancreatography (ERCP), in addition to standard systemic antibiotic therapy, improve clinical outcomes in patients with acute cholangitis…
- Conditions
- Acute Cholangitis, Biliary Tract Infection, Biliary Obstruction, Choledocholithiasis
- Trial name
- NCT07407491
- Testing
- Gentamicin - single dose, Distilled water
- Where
- Malaysia
- Volunteers
- 172 people
- Sponsor
- National University of Malaysia
Common Bile Duct Stones
Role of Routine on-Table Cholangiography in Laparoscopic Cholecystectomy
The purpose of this study is to assess whether routine imaging of the biliary system during routine gallbladder surgery alters clinical outcome
- Trial name
- NCT00806780
- Testing
- on table cholangiography
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Choledocholithiasis
To Compare EUS and MRCP in Detecting Choledocholithiasis in Patients of Intermediate Risk of Choledocholithiasis
A Recent Meta analysis, showed pooled sensitivity and specificity were 97% and 90 for EUS and 87% and 92 for MRCP . This meta analysis includes only 5 studies, smaller sample size in each study, significant heterogeneity in…
- Trial name
- NCT04173624
- Testing
- Endosonography, Magnetic Resonance Cholangiopancreatography
- Where
- India
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Asian Institute of Gastroenterology, India
Common Bile Duct Stricture, Jaundice; Malignant
Efficacy and Safety of Plastic, Covered and Uncovered Self-expandable Metal Stents in the Treatment of Malignant Biliary Obstructions (NEOSTENT)
The aim of the study is to evaluate the efficacy and safety of the various types of stents available for biliary drainage in patients with neoplastic stenosis of the common bile duct and to evaluate the adherence to the current…
- Trial name
- NEOSTENT (NCT05395013)
- Where
- Italy
- Volunteers
- 3,149 people
- Sponsor
- Azienda Unità Sanitaria Locale della Romagna
Choledocholithiasis, Jaundice, Obstructive
Immediate vs. Elective Endoscopic Removal of Large CBD Stones in High-Risk Elderly Patients
The goal of this clinical trial is to compare two different approaches for removing large or multiple stones from the common bile duct in older adults with chronic diseases.
- Trial name
- NCT06948279
- Testing
- The endoscopic retrograde cholangiopancreatography (ERCP) with insertion of a plastic stent., The endoscopic retrograde cholangiopancreatography (ERCP) with immediate stone extraction attempts.
- Where
- Egypt
- Volunteers
- 400 people
- Sponsor
- National Liver Institute, Egypt
Choledocholithiasis
Prospective Comparison of the Carbon Footprint of EUS vs MRCP for Evaluation of Suspected Choledocholithiasis
MRCP and EUS are diagnostically equivalent in detecting CBD stones among patients with intermediate risk, as shown in a landmark RCT.
- Trial name
- NCT07283185
- Where
- India
- Volunteers
- 200 people
- Sponsor
- Asian Institute of Gastroenterology, India
Cholecystolithiasis, Choledocholithiasis
Success of Intraoperative Cholangiography
The purpose of the present study was to evaluate the success of routine use of intraoperative cholangiography (IOC ) and to examine the factors that are hindering the performance of intraoperative c-arm cholangiography.
- Trial name
- NCT04052633
- Testing
- intraoperative cholangiography
- Where
- Finland
- Volunteers
- 201 people
- Sponsor
- Jyväskylä Central Hospital