Clinical trials: Communication, Nonverbal, open to volunteers
Teaching Behaviors, Sign Language Skills
Strategic and Interactive Signing Instruction
Strategic and interactive approaches driven by sociocultural, cognitive, and language theories have accumulated a large body of evidence documenting improvements in more complex oral and written language skills.
- Trial name
- SISI (NCT06667102)
- Testing
- Strategic and Interactive Signing Instruction
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- The University of Tennessee, Knoxville
Healthy
The Effect of Nonverbal Vocalisations on Pain Tolerance
Humans produce non-verbal vocalizations (shouting, growling, screaming), laughter, ...) in various contexts that are likely to perform biological functions. and important social issues.
- Trial name
- VOCPAIN (NCT04425395)
- Testing
- Cold pressor task (CPT), Acoustic Recordings, Index measurement NOL™
- Where
- France
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Autism, Neurodevelopment
Reciprocal Innovation to Optimize Low-Tech Augmentative and Alternative Communication (AAC) for Individuals
Many people with autism and other developmental conditions have difficulty speaking or do not use speech and need other ways to communicate.
- Trial name
- AAC (NCT07581483)
- Testing
- Automated AAC Assessment and Low-Tech AAC Implementation Support, Standard AAC Support
- Where
- 2 sites in United States, Kenya
- Volunteers
- 500 people
- Sponsor
- Indiana University
White Noise
White Noise and Crying Duration After Invasive Procedures in Infants
The aim of this study is to evaluate the effect of white noise applied during invasive procedures (blood sampling or intravenous access) on pain and physical parameters in infants aged 1-3 months.
- Trial name
- NCT07453641
- Testing
- White Noise Audio
- Where
- Turkey (Türkiye)
- Volunteers
- 37 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Cleft Palate Children
Effect of Infant Sign Training on Speech-language Development
Children born with a cleft lip and palate (CLP) are known to be at risk for speech-language disorders that impact academic and social emotional growth.
- Trial name
- NCT06143254
- Testing
- Infant sign training, Verbal training
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- University Hospital, Ghent
Genetic Disease, Nonverbal Communication
Using a Speech-Generating Device to Support Communication in Rare Genetic Conditions
Individuals with rare genetic conditions may experience a delay or loss of developmental skills. Many have limited verbal speech.
- Conditions
- Genetic Disease, Nonverbal Communication, Augmentative and Alternative Communication, Rare Genetic Disease
- Trial name
- NCT07039084
- Testing
- Speech-generating device, Control
- Where
- Australia
- Volunteers
- 38 people
- Sponsor
- Murdoch Childrens Research Institute
Aphasia, Gestures
Effects of Gesture Plus Verbal Treatment (GVT) in Cantonese Speakers With Aphasia
This research aims to explore the relative efficacy of Verbal-only and GVT on naming difficulty in Cantonese-speaking people with aphasia (PWA).
- Trial name
- NCT07455162
- Testing
- Verbal treatment, Gesture plus verbal treatment
- Where
- Hong Kong
- Volunteers
- 90 people
- Sponsor
- Hong Kong University
Fibromyalgia (FM), Pain
Analysis of Facial Expressions for Pain Recognition in Fibromyalgia: Using Artificial Intelligence and Biomarkers
Fibromyalgia (FM) is a chronic musculoskeletal pain syndrome with characteristics of generalized body pain, low pain threshold, tenderness and stiffness in muscles, tendons and joints.
- Conditions
- Fibromyalgia (FM), Pain, Catastrophizing Pain
- Trial name
- Fibromyalgia (NCT06813352)
- Where
- Brazil
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Faculdade de Ciências Médicas de Minas Gerais
Crying
Effects of Melatonin on Excessive Crying in Neonates. A Randomized Controlled Clinical Trial.
the goal of this clinical trial is to learn if melatonin could reduce the duration of excessive crying and infantile colic in neonates and if this drug can be an option to be used in treating such problem- infantile colic and…
- Trial name
- prospective (NCT07442162)
- Testing
- use of multivitamin, one group of neonates with excessive crying receive melatonin orally n=83
- Where
- Iraq
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Al-Hadba university
Healthy
The Effect of Exposure to Aversive Non-verbal Vocalizations on Pain Tolerance
Humans produce non-verbal vocalizations (shouting, growling, screaming), laughter, ...) in various contexts that are likely to perform biological functions. and important social issues.
- Trial name
- CRYPAIN (NCT04423874)
- Testing
- Cold pressor task (CPT), index NOL, Playback Experiments
- Where
- France
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Hyperopia
5 Year Follow up of SMILE® Procedure for the Correction of Hyperopia
The planned study will investigate and evaluate refractive stability, predictability, and safety in patients who underwent SMILE® pro surgery for hyperopia with or without astigmatism at least five years ago.
- Trial name
- PHOBOS-5FU (NCT07133737)
- Where
- 2 sites in Czechia, Germany
- Volunteers
- 100 people
- Sponsor
- Gemini Eye Clinic
Small-incision Lenticule Extraction (SMILE) Surgery, Corneal Higher-order Wavefront Aberrations
Analysis of Influencing Factors of High-Order Aberrations of SMILE With Lenticule Retained
Analysis of Influencing Factors of High-Order Aberrations of SMILE with Lenticule Retained
- Conditions
- Small-incision Lenticule Extraction (SMILE) Surgery, Corneal Higher-order Wavefront Aberrations, Residual Lenticule
- Trial name
- NCT06806085
- Where
- China
- Volunteers
- 33 people
- Sponsor
- Second Affiliated Hospital of Nanchang University
Deep Convolutional Neural Network, Small-incision Lenticule Extraction (SMILE) Surgery
Diagnostic Efficacy of CNN in Predicting Intraoperative Complications and Postoperative Outcomes in SMILE
To evaluate the diagnostic efficiency of the neural network in predicting complications of Small Incision Lenticule Extraction in a multi-center cross-sectional study.
- Conditions
- Deep Convolutional Neural Network, Small-incision Lenticule Extraction (SMILE) Surgery, Intraoperative Complications, Postoperative Outcomes
- Trial name
- NCT06204926
- Testing
- AI diagnostic algorithm
- Where
- China
- Volunteers
- 1,250 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Nanchang University
Autism Spectrum Disorder, Intellectual Disability
Heart Rate Informed Changes in Care for Non-Communicating Patients
The overarching aim is to generate knowledge to reduce incidence of pain in non-verbal patients' everyday life. The trial will 1) evaluate how HR can be used to identify potentially painful care procedures that should be…
- Conditions
- Autism Spectrum Disorder, Intellectual Disability, Communication, Nonverbal
- Trial name
- NCT05738278
- Testing
- HR-informed change in routine, Delayed HR-informed specific change in routine
- Where
- 2 sites in Norway
- Volunteers
- 38 people
- Sponsor
- University of Oslo
Preoperative Anxiety, Laparoscopic Cholecystectomy
Humor-Based Video Intervention on Preoperative Anxiety Veya Humor Video and Recovery in Cholecystectomy
This study aims to evaluate whether watching a short humor-based video before surgery can reduce anxiety and negative emotions and increase positive emotions in patients undergoing elective laparoscopic cholecystectomy…
- Trial name
- NCT07861438
- Testing
- Humor-Based Video Intervention, Routine Preoperative Care and Education
- Where
- Turkey (Türkiye)
- Volunteers
- 136 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Language Disorders, Aphasia
Development and Validation of Language and Communication Assessment Scales
The aim of speech therapy for people with aphasia is to improve their ability to communicate in daily life. Traditional evaluations focus on linguistic tasks, but they do not fully address everyday communication skills, which are…
- Trial name
- SCALE_COM (NCT07518576)
- Testing
- conversational approach
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- IRCCS San Camillo, Venezia, Italy
Newborn; Vitality, Premature Infants
Infant Crying, a Bioacoustic Prognostic Signal for Neurodevelopment
Crying is a vital communication signal for the baby. Product of a complex physiological process, it reflects not only the organization and functioning of the cortical central nervous system and the function of sympathetic and…
- Conditions
- Newborn; Vitality, Premature Infants, Infant Development
- Trial name
- BABYCRY_1000 (NCT06332521)
- Testing
- Acoustic signal analysis method
- Where
- France
- Volunteers
- 1,100 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Smile, Smile Esthetics
Validation of the French Version of the SERQoL Questionnaire
This observational study aims to validate the French version of the Smile Esthetics-Related Quality of Life (SERQoL) questionnaire in adult patients recruited in two APH-HP dental departments.
- Trial name
- Periosmile1 (NCT07372105)
- Where
- France
- Volunteers
- 120 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Laughter
The Effect of Laughter Yoga on Primiparous Pregnant Women
Primiparous women constitute a special risk group who may experience higher levels of fear of childbirth and lower birth self-efficacy during pregnancy due to their lack of prior childbirth experience.
- Trial name
- NCT07360184
- Testing
- Laughter yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Bozok University
Cancer-related Pain, Pain Assessment
Developing a Multimodal Cancer Pain Database to Support AI-Based Automatic Pain Assessment
The goal of this observational study is to collect short video and sound recordings of people with cancer to create a secure database that can be used in future research to develop an artificial intelligence (AI) tool for pain…
- Conditions
- Cancer-related Pain, Pain Assessment, Artificial Intelligence (AI), Oncology
- Trial name
- SENSAI-DBD (NCT07262632)
- Testing
- Audiovisual and questionnaire-based data collection (once), Audiovisual and questionnaire-based data collection (consecutive)
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- Dr. Mark Mulder