Clinical trials: Communications Disorders
Chronic Low Back Pain, Depression
Ketamine-assisted Integrative Treatment for Veterans With Chronic Low Back Pain and Comorbid Depression
This is a pilot study to evaluate the feasibility, acceptability, and safety of ketamine infusions followed by a brief behavioral intervention in Veterans with chronic low back pain and depression.
- Trial name
- NCT06419439
- Testing
- Ketamine hydrochloride, Minimally Enhanced Usual Care, Brief narrative intervention
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- VA Office of Research and Development
Stuttering, Developmental
Non-invasive Brain Stimulation in Adults Who Stutter
Research studies in stuttering have shown that activity patterns in certain brain areas differ in people who stutter compared to people who do not stutter when speaking.
- Trial name
- NCT03437512
- Testing
- Anodal tDCS, Fluency training
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- University of Michigan
Communication, Hypercholesterolemia
Influence of Intervention Methodologies on Patient Choice of Therapy
Few studies have explored how specific formats of effectiveness information effect on real patients' decisions. We only know little about what kind of format would be the optimal to help patients make well-informed real-life…
- Trial name
- IMPACT (NCT01414751)
- Testing
- Absolute risk reduction, Prolongation of life
- Volunteers
- 248 people
- Sponsor
- University of Southern Denmark
Child Language, Language Delay
Talk With Me Baby: Leveraging Well-Child Care to Enhance the Early Home Language Environment
Language-rich interactions with a parent or caregiver can serve as a protective factor for young children, by supporting their language development and other positive long-term outcomes, but existing interventions have not had…
- Conditions
- Child Language, Language Delay, Developmental Milestones
- Trial name
- TWMB (NCT07132411)
- Testing
- Patients in Talk With Me Baby Clinics, Patients in Care-As-Usual Clinics
- Where
- 2 sites in United States
- Volunteers
- 400 people
- Sponsor
- University of Kansas Medical Center
Aphasia, Anomia
Effects of Verb Network Strengthening Treatment (VNeST) Via Telerehabilitation on Word Finding in Post-stroke Aphasia.
Despite evidence showing that speech and language intervention may improve language and communication abilities in people with acquired language disorders (aphasia), there is still need for evidence for which types of therapy are…
- Conditions
- Aphasia, Anomia, Stroke
- Trial name
- NCT06096662
- Testing
- Verb Network Strenghtening Treatment (VNeST)
- Where
- Sweden
- Volunteers
- 10 people
- Sponsor
- Vastra Gotaland Region
Autistic Disorder of Childhood Onset With Full Syndrome
Impact of Sports Activity on Pragmatic Skills of Children
To investigate the effects of structured physical exercises/outdoor sports on social interaction/communication skills of children with Autism in Pakistan.
- Trial name
- NCT04593576
- Testing
- Physical activity protocol/out door sports, Intensive table teaching speech therapy
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University
Ambient AI System, Emergency Department
Evaluation of a Generative AI-Based Voice Documentation System for Patient-Clinician Communication in the Emergency Department and Its Impact on Clinical Workflow Efficiency and Usability
This research study at Samsung Medical Center evaluates the impact of Ambient AI system, a Generative AI-based communication and documentation system developed by NAVER, on the efficiency and quality of medical record-keeping…
- Conditions
- Ambient AI System, Emergency Department, Generative ai
- Trial name
- CLOVA Charty (NCT07637591)
- Testing
- VoiceEMR
- Where
- South Korea
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Stroke, Aphasia
Effects of Transcranial Direct Current Stimulation (tDCS) on Language
This study will investigate the effects of mild electrical stimulation in conjunction with speech therapy for people with post-stroke aphasia to enhance language recovery.
- Trial name
- NCT04166513
- Testing
- Targeted Transcranial Direct Current Stimulation, Active Control Transcranial Direct Current Stimulation, Phonologic-Focused Speech Therapy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Medical College of Wisconsin
Tetraplegia, Guillain-Barre Syndrome
Brain Computer Interface for Communication in ICU: a Feasibility Study
The main objective of this study is to evaluate the usability of a system to assist verbal communication based on BCI system using the P300 wave in patients with tetraplegia who can no longer communicate because of severe engine…
- Trial name
- RoBIK-1 (NCT01005524)
- Where
- France
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Versailles
Scoliosis Idiopathic, Scoliosis; Adolescence
Improving Adherence and Safety of Orthopedic Treatment of Idiopathic Scoliosis in Adolescents Using Information and Communication Technologies
The present project aims to test the feasibility of a new management mechanism for inter-visit monitoring of adolescent patients with idiopathic scoliosis that improves the quality and safety of current orthopedic treatments…
- Conditions
- Scoliosis Idiopathic, Scoliosis; Adolescence, Brace
- Trial name
- NCT04881591
- Testing
- Treatment as usual + APP
- Where
- Spain
- Volunteers
- 10 people
- Sponsor
- Universitat Jaume I
Shared Decision-making, Kidney Stone
Shared Decision-Making for the Promotion of Patient-Centered Imaging in the ED: Suspected Kidney Stones
Although a CT scan is required for some Emergency Department patients with signs and symptoms of a kidney stone, recent evidence has shown that routine scanning is unnecessary and may expose young patients to significant…
- Conditions
- Shared Decision-making, Kidney Stone, Emergencies, Radiation Exposure
- Trial name
- ED-KSS (NCT04234035)
- Testing
- Decision Aid, Standardized Educational Material (informational pamphlet)
- Where
- United States
- Volunteers
- 98 people
- Sponsor
- Baystate Medical Center
Sugar Sweetened Beverage Consumption, Nutrition
Testing Message Modality of Culturally Appropriate Nutrition Communication for Mexican American Women
A randomized controlled trial to test the effects of culturally appropriate nutrition communication delivered via different modalities for Mexican American women.
- Conditions
- Sugar Sweetened Beverage Consumption, Nutrition, Lifestyle-related Condition, Lifestyle Risk Reduction
- Trial name
- NCT04710108
- Testing
- Health Communication
- Where
- United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- University of California, Merced
Locked-in Syndrome
Brain-Computer Interface Implant for Severe Communication Disability
Locked-In Syndrome (LIS) is a devastating condition in which a person has lost the ability to communicate due to motor impairment, while being mentally intact.
- Trial name
- NCT04576650
- Testing
- Summit System
- Where
- United States
- Sponsor
- Johns Hopkins University
Hoarding Disorder
In-home Decluttering Augmentation of Group CBT for HD
The primary aim of trial is to determine the clinical efficacy of in-home decluttering augmentation of group CBT for reducing hoarding severity in adults with HD. The trial takes place in Sweden.
- Trial name
- NCT04712474
- Testing
- In-home decluttering practice
- Where
- Sweden
- Volunteers
- 90 people
- Sponsor
- Karolinska Institutet
Frontotemporal Dementia, FTD
A Study to Evaluate the Safety and Effect of AVB-101, a Gene Therapy Product, in Subjects With a Genetic Sub-type of Frontotemporal Dementia (FTD-GRN)
The goal of this clinical study is to learn about an investigational gene therapy product called AVB-101, which is designed to treat a disease called Frontotemporal Dementia with Progranulin Mutations (FTD-GRN).
- Conditions
- Frontotemporal Dementia, FTD, FTD-GRN, Dementia, Frontotemporal
- Trial name
- ASPIRE-FTD (NCT06064890)
- Testing
- Intrathalamic AAV.PGRN administration, Intrathalamic AVB-101
- Where
- 19 sites in United States, Belgium and 7 more
- Volunteers
- 18 people
- Sponsor
- AviadoBio Ltd
Obsessive Compulsive Disorder (OCD), Bipolar Disorders
Assess the Utility of a Speech-based Machine Learning Algorithm to Predict Treatment Response to Psychiatric Interventions
This is a research study looking at whether the way people speak can help predict how well they'll respond to certain mental health treatments.
- Conditions
- Obsessive Compulsive Disorder (OCD), Bipolar Disorders, Major Depressive Disorder, Post-Traumatic Stress Disorder, PTSD
- Trial name
- NCT06823024
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Psyrin Inc.
Morals, Covid19
Medical Triage in a Time of Scarce Resources.
The XPHI-COVID-2 randomized study aims to investigate the moral choices in a context of scarce resources. The participants are asked to complete the questionnaire of the Oxford Utilitarianism Scale and are exposed to medical…
- Conditions
- Morals, Covid19, Ethics, Narrative
- Trial name
- XPHI-COVID-2 (NCT04982770)
- Testing
- Survey
- Where
- France
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Autism Spectrum Disorder
ML-004 Open-Label Extension Study in Adults and Adolescents With Autism Spectrum Disorders (ASD)
ML-004-003 is a multi-center, open-label extension study that will enroll approximately 120 adolescent and adult subjects with ASD that have completed study ML-004-002.
- Trial name
- NCT05889273
- Testing
- ML-004 (IR)/(ER) tablet
- Where
- 21 sites in United States, Australia and 1 more
- Volunteers
- 120 people
- Sponsor
- MapLight Therapeutics
Hypoglycemia, Hypoglycemia Acute
Electronic Platform for Diabetic Patients Activation
The purpose of this study is to assess the efficacy of an electronic platform for doctor-patient communication in order to reduce severe and non-severe hypoglycemia events as well as inadvertent hypoglycemia events.
- Trial name
- INSULINCOM (NCT04595383)
- Testing
- ti.care
- Volunteers
- 106 people
- Sponsor
- Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana
Aphasia, Stroke
The Effect of Non-invasive Brain Stimulation on Language Production in Post-stroke Aphasia
Aphasia is a language impairment caused by brain injury such as stroke that affects the ability to understand and express language, read and write due to damage in the language regions of the brain.
- Conditions
- Aphasia, Stroke, Language Disorders
- Trial name
- NCT04204356
- Testing
- Language treatment for improving discourse production, Transcranial direct-current stimulation (tDCS)
- Where
- United Kingdom
- Volunteers
- 6 people
- Sponsor
- King's College London
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