Clinical trials: Community Pneumonia
Community Pneumonia
The Association Mechanism Between the Microbiome and the Development of Community Pneumonia Was Studied Based on the Analysis of Pulmonary Microbiota - Host Interaction Network
1. The difference of lung flora between the healthy group and the CAP group was compared, and the core flora involved in the development of CAP was identified. 2. To predict the metabolites associated with CAP. 3.
- Trial name
- NCT06896019
- Testing
- Community Pneumonia
- Where
- China
- Volunteers
- 37 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Pneumonia, Pneumonia - Bacterial
Derivation and Validation of the Risk Evaluation Score for Pneumonia Involving Resistant Entities (RESPIRE)
This is a single-center, non-profit observational study with two sequential phases: an initial retrospective phase followed by a prospective phase. Patients were enrolled during two consecutive, non-overlapping periods.
- Conditions
- Pneumonia, Pneumonia - Bacterial, Multi Drug Resistant, Multi Drug Resistant Organisms
- Trial name
- RESPIRE (NCT07425561)
- Testing
- RESPIRE score
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Mental Stress, Mental Health Wellness 1
Mental Health Assessment Among Community Member During the Covid-19 Pandemic in Indonesia
The Covid-19 pandemic in Indonesia makes several changes in daily living. The Indonesian government suggests that everyone should stay at home by implements the work from home and school from home.
- Conditions
- Mental Stress, Mental Health Wellness 1, Depression, Anxiety
- Trial name
- New (NCT04343664)
- Where
- Indonesia
- Volunteers
- 10,000 people
- Sponsor
- Tjhin Wiguna
Community-acquired Pneumonia
Efficacy and Safety of Trimodulin (BT588) in Subjects With Severe Community-acquired Pneumonia (sCAP)
The main objective of the trial is to assess the efficacy and safety of trimodulin as adjunctive treatment to standard of care (SoC) compared to placebo plus SoC in hospitalized subjects with sCAP on invasive mechanical…
- Trial name
- ESsCAPE (NCT05722938)
- Testing
- Trimodulin
- Where
- 170 sites in United States, Argentina and 16 more
- Volunteers
- 590 people
- Sponsor
- Biotest
Community Acquired Pneumonia
Population Pharmacokinetics of Cephalosporins and Macrolides in Chinese Children With Community Acquired Pneumonia
This study is based on the hypothesis that the pharmacokinetics of antibiotics in children is different from adults. Cephalosporins and macrolide antibiotics are the common drugs for children with community acquired pneumonia…
- Trial name
- NCT02775968
- Testing
- Cephalosporins and Macrolide Antibiotics
- Where
- China
- Volunteers
- 750 people
- Sponsor
- Beijing Children's Hospital
Pneumonia, Pneumococcal, Vaccines, Pneumococcal
Epidemiologic Study Of The Distribution Of Vaccine-Type Streptococcus Pneumoniae Serotypes In Adults In The US With Community-Acquired Pneumonia
The main purpose of this study is to use an investigational urine assay to estimate the proportion of pneumonia in adults 50 years or older in different areas throughout the US that is caused by certain types of the bacteria…
- Trial name
- NCT01086397
- Testing
- Urine sample collection
- Where
- 14 sites in United States
- Volunteers
- 782 people
- Sponsor
- Pfizer
Community Acquired Pneumonia
A P3 Comparator Trial in Community Acquired Bacterial Pneumonia
This study will be a double-blind, randomized, multicenter trial to assess the safety and efficacy of a single 1500 mg IV dose of dalbavancin plus a single 500 mg IV dose of azithromycin in comparison to an approved antibiotic…
- Trial name
- NCT02269644
- Testing
- Dalbavancin, Linezolid, Azithromycin
- Where
- United States
- Sponsor
- Durata Therapeutics Inc., an affiliate of Allergan plc
Covid19
SCALE-UP Utah: Community-Academic Partnership to Address COVID-19 Vaccination Rates Among Utah Community Health Centers
SCALE-UP Utah is a community-academic partnership to address COVID-19 among Utah community health centers. The long-term objective of the project is to increase the reach, acceptance, and uptake of COVID-19 vaccines among Utah's…
- Trial name
- NCT04939519
- Testing
- Text-Messaging (TM), Patient Navigation (PN)
- Where
- United States
- Volunteers
- 65,300 people, healthy volunteers welcome
- Sponsor
- University of Utah
Community Acquired Pneumonia (CAP)
ItAlian ReGistry Of pNeumoniA in immUnocompromised paTients (ARGONAUT)
This multicentric, prospective study aims at: evaluating the prevalence, etiology, characteristics, and 1one-year outcomes of immunocompromised patients hospitalized for Community-Acquired Pneumonia (CAP); conducting biochemical…
- Trial name
- ARGONAUT (NCT06755814)
- Where
- Italy
- Volunteers
- 1,298 people
- Sponsor
- Societa Italiana di Pneumologia
Covid19, Vaccine Reaction
Immunogenicity Against SARS-CoV-2 in COVID-19 Close Contacts
This study will investigate the presence of SARS-CoV-2 neutralizing antibody and its association with demographic information, medical history of SARS-CoV-2 infected individuals, exposure history of close contacts, vaccination…
- Trial name
- NCT05094635
- Testing
- SARS-CoV-2 IgG II Quant
- Where
- Vietnam
- Volunteers
- 772 people
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Pneumonia, Pneumonia Childhood
Novel Tools to Improve Management of Paediatric Community-Acquired Pneumonia - ToolCAP
The ToolCAP study aims to see if using ultrasound to look at the lungs when children have symptoms of a lung infection will safely allow doctors to improve how they treat those infections.
- Conditions
- Pneumonia, Pneumonia Childhood, Pneumonia - Bacterial, Pediatrics
- Trial name
- ToolCAP (NCT06670833)
- Testing
- Lung ultrasound, Standard of Care (SOC)
- Where
- 9 sites in Senegal, South Africa and 1 more
- Volunteers
- 4,894 people
- Sponsor
- Ecole Polytechnique Fédérale de Lausanne
Community-acquired Pneumonia
Multicenter Epidemiologic Study of Severe Community Acquired Pneumonia in China
This study is aimed to understand the clinical characteristics, etiology and resistance phenotype of major pathogens of SCAP in China through multicenter and prospective investigation.
- Trial name
- NCT03728816
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Ruijin Hospital
Community-acquired Pneumonia, Acute Respiratory Distress Syndrome
Two Different Ventilatory Strategies in Acute Respiratory Distress Syndrome Due to Community-acquired Pneumonia
Randomized Controlled Trial Comparing Two Different Ventilatory Strategies in Acute Respiratory Distress Syndrome Due to Community-acquired Pneumonia. The control strategy will be based on ARDSNet approach.
- Trial name
- STAMINA (NCT04972318)
- Testing
- Positive end-expiratory pressure titration with driving pressure control, ARDSNet ventilatory strategy
- Where
- 6 sites in Brazil
- Volunteers
- 214 people
- Sponsor
- Hospital do Coracao
Acute Respiratory Failure, Community-Acquired Pneumonia
Early Inflammatory-Immune Stratification and Precision Glucocorticoid Intervention in Acute Respiratory Failure Induced by Community-Acquired Pneumonia
This is a prospective, multicenter, interventional cohort study aimed at constructing a high-quality, dynamic multimodal database for patients with acute respiratory failure caused by community-acquired pneumonia (CAP-ARF).
- Trial name
- NCT07357935
- Testing
- Methylprednisolone
- Volunteers
- 500 people
- Sponsor
- Qingyuan Zhan
Pneumonia
A Study on Pathogenic Surveillance and Nasopharyngeal Carriage of Children and Adolescents Based on Hospitals and Communities in Hainan Province
This study intends to screen children under the age of 10 for respiratory pathogens, Streptococcus pneumoniae, and serotyping in three representative cities in Hainan province: Haikou, Wanning, and Baisha, in order to provide a…
- Trial name
- NCT05912010
- Testing
- NP/OP swab
- Where
- 5 sites in China
- Volunteers
- 3,746 people, healthy volunteers welcome
- Sponsor
- Huashan Hospital
Mental Health Issue, COVID-19
Music Mindfulness Study 2a.
Mental health vulnerability due to stress is increased in People of African Descent (PADs) in America due to disproportionate effects of racism, poverty, education, and criminal justice sentencing.
- Trial name
- NCT06505226
- Testing
- in person meditation, in person meditation using headphones, virtual meditation
- Where
- 2 sites in United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Yale University
Pneumonia, Pediatric Respiratory Diseases
Supportive Treatment and Antibiotics for Mild Pediatric Pneumonia
National guidelines make two recommendations for treatment of young children with mild pneumonia - one to avoid routine antibiotics and another to use narrow-spectrum antibiotics.
- Conditions
- Pneumonia, Pediatric Respiratory Diseases, Antibiotic Use, Community-acquired Pneumonia
- Trial name
- STAMPP (NCT05726253)
- Testing
- Supportive Care + Amoxicillin
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
COVID-19, Trust
Community-Led COVID-19 Testing Intervention to Address Mistrust
The goal of this adapted intervention study is to assess how community-led group discussions about health-related topics may alter beliefs and intentions regarding healthcare recommendations, such as COVID-19 testing and…
- Trial name
- NCT07166770
- Testing
- Community-led discussion
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Old Dominion University
COVID-19, Undefined
A Clinical Safety Study on AT-100 in Treating Adults With Severe COVID-19 Infection or Severed Community Acquired Pneumonia
The purpose of this study is to determine if an investigational drug, AT-100, is safe and tolerated by adults who have severe corona virus disease 2019 (COVID-19) or respiratory failure secondary to severe community acquired…
- Trial name
- NCT04659122
- Testing
- AT-100
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Airway Therapeutics, Inc.
Pneumonia, Diagnoses Disease
Ultra-low Dose Chest Computed Tomography: a Rule-out Tool for Community-acquired Pneumonia
This is a randomized study that sought to compare the rule-out capacity and antibiotics prescriptions associated with two different diagnostic imaging strategies (ultra-low-dose chest computed tomography versus chest radiography)…
- Trial name
- NCT04541160
- Testing
- CR, ULDCT
- Where
- Brazil
- Volunteers
- 237 people
- Sponsor
- Hospital Israelita Albert Einstein