Clinical trials: Community Pneumonia
Pneumonia
Japanese Study Evaluating the Effects of Telithromycin in Children With Community-Acquired Pneumonia
The primary objective is to assess the safety of telithromycin (HMR3647) 20 mg/kg qd for 5-7 days in children with community-acquired pneumonia (CAP).
- Trial name
- NCT00638859
- Testing
- Telithromycin (HMR3647)
- Where
- Japan
- Volunteers
- 56 people
- Sponsor
- Sanofi
Community Acquired Bacterial Pneumonia
Study to Compare Delafloxacin to Moxifloxacin for the Treatment of Adults With Community-acquired Bacterial Pneumonia
The purpose of this study is to evaluate the safety and efficacy of delafloxacin compared to moxifloxacin in the treatment of adult patients with community-acquired pneumonia.
- Trial name
- DEFINE-CABP (NCT02679573)
- Testing
- Delafloxacin, Moxifloxacin, Linezolid
- Where
- 90 sites in United States, Argentina and 16 more
- Volunteers
- 860 people
- Sponsor
- Melinta Therapeutics, Inc.
Lower Respiratory Tract Infection (LRTI)
Procalcitonin Antibiotic Consensus Trial (ProACT)
The ProACT study is a 5 year, multicenter study that will test the effect of implementation of a novel procalcitonin guideline on antibiotic use and adverse outcomes in Emergency Department (ED) patients with Lower Respiratory…
- Trial name
- ProACT (NCT02130986)
- Testing
- Procalcitonin level, Results of procalcitonin (PCT) level to treating clinician, Provide procalcitonin guideline to treating clinician
- Where
- 13 sites in United States
- Volunteers
- 1,664 people
- Sponsor
- University of Pittsburgh
Community-acquired Pneumonia, CAP
Inhaled Lexofloxacin vs Usual Care for Treatment of Community-Acquired Pneumonia
This trial aims to determine whether treatment with inhaled levofloxacin (an antibiotic) is equal to systemic antibiotic treatment (usual care) for patients admitted to a hospital with community-acquired pneumonia in regards to…
- Conditions
- Community-acquired Pneumonia, CAP, Community Acquired Pneumonia, Pneumonia
- Trial name
- LANDCAP 2 (NCT07843017)
- Testing
- Inhaled levofloxacin, Standard-of-care / Usual care
- Where
- Denmark
- Volunteers
- 460 people
- Sponsor
- Copenhagen Respiratory Research
Pneumonia, Pneumococcal, Pneumococcal Infections
Study Evaluating the Effiacy of a 13-Valent Pneumococcal Conjugate Vaccine (13vPnC) in Adults
The purpose of this study is to assess the efficacy of 13-valent pneumococcal conjugate vaccine in the prevention of the first episode of vaccine-type pneumococcal community-acquired pneumonia in adults.
- Conditions
- Pneumonia, Pneumococcal, Pneumococcal Infections, 13-valent Pneumococcal Vaccine
- Trial name
- CAPITA (NCT00744263)
- Testing
- VACCINE: 13-valent pneumococcal conjugate vaccine
- Where
- 159 sites in Netherlands
- Volunteers
- 84,496 people, healthy volunteers welcome
- Sponsor
- Pfizer
COVID-19
SCALE-UP Utah II: Community-Academic Partnership to Address COVID-19 Text Message Study
The long-term objective of SCALE-UP II is to increase the reach, uptake, and sustainability of COVID-19 testing among underserved populations.
- Trial name
- NCT05533918
- Testing
- Text-Messaging (TM), Patient Navigation (PN)
- Where
- United States
- Volunteers
- 31,439 people
- Sponsor
- University of Utah
COVID-19
Community-based Sero-epidemiological Study of COVID-19
Using detailed serial cross-sectional estimates of the age-specific distribution of SARS-CoV-2 Omicron variant-specific antibody positivity levels, the investigators derived age-specific infection attack rates and age-specific…
- Trial name
- NCT05599555
- Testing
- mRNA BNT162b2 vaccine, CoronaVac vaccine
- Where
- Hong Kong
- Volunteers
- 9,600 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
COVID-19
Improving COVID-19 Vaccine Uptake Among Black and Latino Youth
Black and Latino youth may be less likely to get the COVID-19 vaccine than White youth. In this study we will work with community members to come up with ways to help Black and Latino families learn more about the COVID-19…
- Trial name
- NCT05293392
- Testing
- Culturally-Tailored COVID-19 Vaccine Uptake Intervention, Standard Care
- Where
- United States
- Volunteers
- 5,792 people
- Sponsor
- Nemours Children's Health System
Community-acquired Pneumonia
Clinical Pathway Based on Procalcitonin Levels for the Management of Community-acquired Pneumonia in Outpatients
A clinical protocol was developed for the management of adult outpatients with community-acquired pneumonia (CAP) and Pneumonia Severity Index risk classes I-II.
- Trial name
- NCT02600806
- Testing
- Azithromycin, Levofloxacin
- Where
- Spain
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana
Community Acquired Pneumonia
Multicenter Intervention Program to Optimize the Clinical Management of Community-acquired Pneumonia in Hospitals
The purpose of this study is to evaluate the impact of a structured package (bundle) in reducing the use of antimicrobials and hospital stay of patients with community-acquired pneumonia (CAP), and no increase in mortality of…
- Trial name
- NCT02224716
- Where
- Spain
- Volunteers
- 968 people
- Sponsor
- Fundación Pública Andaluza Progreso y Salud
Pneumococcal Disease
Serotype Distribution of Chest X-ray Confirmed Pneumococcal Community Acquired Pneumonia in the Adult Population in Greece, Over 1 Year.
Serotype distribution and estimation of antimicrobial resistance in S. pneumoniae isolates and anticipated PCV7 and PCV13 coverage is difficult in Greece, because invasive isolates collected each year are limited and depict a…
- Trial name
- B1851065 (NCT01564771)
- Testing
- Non Intervention
- Where
- 21 sites in Greece
- Volunteers
- 293 people
- Sponsor
- Pfizer
Community-Acquired Pneumonia
Azithromycin Microspheres in Patients With Low Risk Community Acquired Pneumonia
The study will assess the clinical efficacy at Day 14-21 (Test of Cure), 14-21 days after starting the study drug; those subjects from whom a baseline pathogen is identified will also be assessed for bacteriologic response.
- Trial name
- NCT00140023
- Testing
- Azithromycin microspheres 2.0 single dose
- Where
- 5 sites in Philippines
- Volunteers
- 47 people
- Sponsor
- Pfizer
Mental Health Issue, COVID-19
Evaluating the Impact of Social Music
Mental health vulnerability due to stress is increased in People of African Descent (PADs) in America due to disproportionate effects of racism, poverty, education, and criminal justice sentencing.
- Trial name
- NCT06513910
- Testing
- Music
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Yale University
Community Acquired Pneumonia
Lung Ultrasound for Community-acquired Pneumonia Diagnosis in Emergency Medicine
Community-acquired pneumonia (CAP) is frequently suspected in the Emergency Department (ED). However, usual diagnosis procedure based on clinical features and chest X-Ray has rather bad performances.
- Trial name
- ECHOPAC (NCT03411824)
- Testing
- no intervention
- Where
- 4 sites in France
- Volunteers
- 90 people
- Sponsor
- Nantes University Hospital
Influenza, Community-acquired Pneumonia
Fluad vs. Fluzone High-Dose Vaccine Effectiveness Among Adults ≥65 Years
This study will evaluate the relative vaccine effectiveness of quadrivalent adjuvanted inactivated influenza vaccine (aIIV4) versus quadrivalent high-dose inactivated influenza vaccine (HD-IIV4) in preventing polymerase chain…
- Conditions
- Influenza, Community-acquired Pneumonia, Cardiovascular Events
- Trial name
- NCT06029933
- Testing
- Adjuvanted Quadrivalent Inactivated Influenza Vaccine (aIIV4), High-Dose Quadrivalent Inactivated Influenza Vaccine (HD-IIV4)
- Where
- United States
- Volunteers
- 1,500,000 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Community Acquired Pneumonia (CAP), Hospital Acquired Pneumonia
Pneumonia Pathogens' Virulence Factors, Patient Inflammatory Markers, and Their Associations With Outcomes
The study aims to evaluate pneumonia symptoms using physical examinations, radiological and laboratory tests, and prognostic scales such as the Pneumonia Severity Index (PSI) and CURB65.
- Trial name
- Pneumonia-1 (NCT07011433)
- Testing
- Inflammatory Biomarker Evaluation
- Where
- Lithuania
- Volunteers
- 300 people
- Sponsor
- Ruta Nutautiene
Diabetes, COVID-19
RADx-UP- Impact of Community Health Worker Deployment
The proposed project will implement and evaluate a brief Community Health Worker (CHW) intervention through the Albany Area Primary Health Care, a rural Federally Qualified Health Center (FQHC).
- Conditions
- Diabetes, COVID-19, Community Health Workers, Health Behavior
- Trial name
- NCT05863884
- Testing
- Impact of Community Health Worker Home Deployment on COVID-19 Vaccine Confidence and Uptake
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Morehouse School of Medicine
Pneumonia
Community-Acquired Pneumonia (CAP) Surveillance
Prospective, non-interventional, multi-center study. 7 investigative centers will involved in China. Around 560 CAP outpatients or inpatients will be screened until 56 M. pneumoniae isolates collected.
- Trial name
- NCT01416506
- Testing
- No Drug
- Where
- China
- Volunteers
- 560 people
- Sponsor
- Bayer
Community Acquired Pneumonia, Bacterial Pneumonia
Study Evaluating Tigecycline vs Levofloxacin in Hospitalized With Community-Acquired Pneumonia
To compare the efficacy and safety of tigecycline with those of levofloxacin in the treatment of subjects with CAP requiring hospitalization.
- Conditions
- Community Acquired Pneumonia, Bacterial Pneumonia, Cross Infection
- Trial name
- NCT00079885
- Testing
- tigecycline
- Volunteers
- 430 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Pneumonia
Community Case Management of Chest Indrawing Pneumonia
This one-arm safety intervention study is aimed at increasing access to treatment of pneumonia by training CHWs, locally referred to as Community Oriented Resource Persons (CORPs), to manage chest indrawing pneumonia using oral…
- Trial name
- NCT02878031
- Testing
- Oral amoxicillin for CI pneumonia
- Where
- Nigeria
- Volunteers
- 191 people
- Sponsor
- Malaria Consortium