Clinical trials: Community Pneumonia
Community Acquired or Acquiring Hospital Acquired Pneumonia
Definition of Sub-phenotypes of Pneumonia Based on the Respiratory Microbiome Composition to Predict Microbial and Clinical Treatment Failures
Background: Pneumonia remains a leading cause of antibiotic consumption globally, contributing significantly to the burden of antimicrobial resistance (AMR).
- Trial name
- PHENOMENON (NCT06916481)
- Where
- 6 sites in France
- Volunteers
- 300 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
COVID-19, Trust
Evaluating a Community-Led COVID-19 Testing Intervention to Address Mistrust - Study 1
The goal of this study is to assess how community-led group discussions about health-related topics may alter beliefs and intentions regarding healthcare recommendations, such as COVID-19 testing and vaccination.
- Trial name
- NCT06650462
- Testing
- Community-led discussion
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Old Dominion University
Pneumonia, Chronic Obstructive Pulmonary Disease
Evaluation of Plasma Sphingosine-1-Phosphate as A Diagnostic and Prognostic Biomarkers of Community-Acquired Pneumonia
Pneumonia is a major infectious cause of death worldwide and imposes a considerable burden on healthcare resources. Obstructive lung diseases (COPD and Asthma) are increasingly important causes of morbidity and mortality…
- Conditions
- Pneumonia, Chronic Obstructive Pulmonary Disease, Asthma
- Trial name
- NCT03473119
- Where
- Taiwan
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University WanFang Hospital
ARDS (Acute Respiratory Distress Syndrome)
Time-controlled Adaptive Ventilation (TCAV) Compared With Conventional Ventilation in Patients With Moderate-to-severe Acute Respiratory Distress Syndrome (ARDS) Secondary to Community-acquired Pneumonia
ARDS is a pathology with mortality rates reaching 40%. Invasive ventilation, the cornerstone of ARDS management, leads to "ventilation-induced lung injury" (VILI).
- Trial name
- EARLY-TCAV (NCT07679802)
- Testing
- Invasive ventilation with the Time-controlled Adaptative Ventilation settings applied to the Airway Pressure Release Ventilation mode, Volume Control
- Where
- France
- Volunteers
- 56 people
- Sponsor
- Central Hospital, Nancy, France
Community-acquired Pneumonia
Postural Drainage and PEP Technique in Community Acquired Pneumonia
Community-acquired pneumonia is acquired outside the hospital. Postural drainage is the positioning of a patient with an involved lung segment such that gravity has a maximal effect of facilitating the drainage of…
- Trial name
- NCT05356494
- Testing
- Postural drainage, Positive expiratory pressure
- Where
- Pakistan
- Volunteers
- 46 people
- Sponsor
- Riphah International University
Sinusitis, Bronchitis, Chronic
Outcomes of Patients Not Responding to Antibiotics in the Community
A study to report the outcomes of patients who fail to respond to beta-lactam and macrolide antibiotics in the community
- Conditions
- Sinusitis, Bronchitis, Chronic, Pneumonia, Bacterial
- Trial name
- NCT00245427
- Testing
- all macrolide antibiotics, all beta-lactam antibiotics
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- CPL Associates
Pandemic, COVID-19, Infections
Bern, Get Ready (BEready) Cohort Study for Pandemic Preparedness
The BEready project aims to find out how people in the Canton of Bern can be helped to be more prepared for the next pandemic. BEready wants to understand how infections spread among people as well as between people and animals.
- Conditions
- Pandemic, COVID-19, Infections, Zoonoses, Epidemic Disease
- Trial name
- BEready (NCT06739499)
- Where
- Switzerland
- Volunteers
- 2,157 people, healthy volunteers welcome
- Sponsor
- University of Bern
Pneumonia, Child
Predicting Severe Outcomes Among Children Hospitalized With Community-acquired Pneumonia
In this study, investigators aimed to develop and validate a risk score to predict severe outcomes (e.g., mortality and ICU admission) in children who were admitted to the Children's Hospital of Fudan University between 2017 and…
- Conditions
- Pneumonia, Child, Prognosis
- Trial name
- NCT05744609
- Testing
- exposures of interest: epidemiological data, clinical characteristics, laboratory data, and chest radiographic reports
- Where
- China
- Volunteers
- 6,000 people
- Sponsor
- Children's Hospital of Fudan University
Pneumonia, Community-Acquired
A Trial Of Azithromycin SR For The Treatment Of Mild To Moderate Community Acquired Pneumonia In Japanese Adults
To evaluate the clinical efficacy and safety in patients with mild or moderate community-acquired pneumonia receiving a dose of 2 g of azithromycin in the SR formulation.
- Trial name
- NCT00360295
- Testing
- Azithromycin SR
- Where
- 54 sites in Japan
- Volunteers
- 153 people
- Sponsor
- Pfizer
Community-Acquired Pneumonia
Community-acquired Pneumonia Due to Chlamydia Pneumoniae
This international retrospective Franco-Swiss study focuses on community-acquired pneumonia (CAP) caused by Chlamydia pneumoniae. The working hypothesis is that the prevalence of C.
- Trial name
- CHLAMPAC (NCT07679789)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier de Saint-Denis
Community Acquired Respiratory Disease Syndrome
Extended Steroid in Use in Community Acquired Pneumonia (CAP)(e)
The goal of the study is to determine whether providing early treatment with a glucocorticoid drug, called methylprednisolone, will improve survival in critically ill patients with severe community-acquired pneumonia (CAP).
- Trial name
- ESCAPe (NCT01283009)
- Testing
- Inactive Substance, Methylprednisolone
- Where
- 30 sites in United States, Puerto Rico
- Volunteers
- 584 people
- Sponsor
- VA Office of Research and Development
Covid19
Home-based Care and Hand Hygiene Interventions in Honduras
This study aims to enroll patients with acute infection with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) who do not meet criteria for hospital admission according to protocols developed by the Honduras Ministry…
- Trial name
- NCT04886414
- Testing
- Phone-based monitoring, Oxygen saturation monitoring, Alcohol-based hand sanitizer
- Where
- Honduras
- Volunteers
- 1,821 people
- Sponsor
- Brigham and Women's Hospital
Hypertension (HTN), Diarrhea
Mortality Control Program for Economically Productive Age Group in Tribal Area of Melghat.
Background: Age specific mortality rate (ASMR) of 16-60 years is very high in Indian tribal areas due to communicable and non-communicable diseases.
- Conditions
- Hypertension (HTN), Diarrhea, Pneumonia, Malaria Fever
- Trial name
- MCPEPAG (NCT07436104)
- Testing
- Trained village health workers (VHWs) , provided treatment of HTN, diarrhoea, malaria, pneumonia, asthma and COPD by Amlodipine, ORS, Norfloxacin, Chloroquine, Azithromycin, salbutamol rotacaps, Appropriate referral
- Where
- India
- Volunteers
- 72,564 people, healthy volunteers welcome
- Sponsor
- MAHAN Trust
Covid19
Feasibility of Ayurveda in Patients With Mild-to-Moderate COVID-19: A Community-Based Participatory Research
Innovative strategies are required to manage COVID-19 in the communities. Back to Roots community based project was a collaborative, pilot intervention program in British Asian community to assess the efficacy and safety of…
- Trial name
- NCT04716647
- Testing
- Ayurveda
- Where
- United Kingdom
- Volunteers
- 28 people
- Sponsor
- Aarogyam UK
Community-acquired Pneumonia, Hospital-acquired Pneumonia
Diagnostic Performance and Impact of a Multiplex PCR Pneumonia Panel in ICU Patients With Severe Pneumonia.
The objective of this study is to assess the diagnostic performance of multiplex respiratory PCR (PCR-RM) compared to standard microbiological tests and its potential impact on the early adaptation of antibiotic treatment in…
- Conditions
- Community-acquired Pneumonia, Hospital-acquired Pneumonia, Ventilator Associated Pneumonia
- Trial name
- NCT05624684
- Testing
- Multiplex respiratory PCR
- Where
- Morocco
- Volunteers
- 210 people
- Sponsor
- Avicenna Military Hospital
Childhood Pneumonia
Cotrimoxazole Versus Amoxicillin in the Treatment of Community Acquired Pneumonia in Children Aged 2-59 Months
The investigators hypothesized that Oral amoxicillin (25mg/kg/dose bid) given to children aged 2-59 months with pneumonia, would lead to better clinical outcome on day three in 89.9% of the children compared to 77.0% of children…
- Trial name
- NCT00933049
- Testing
- Amoxicillin, Cotrimoxazole
- Where
- Uganda
- Volunteers
- 505 people
- Sponsor
- Makerere University
Infectious Disease of Lung, Molecular Diagnosis
Clinical Impact of a Multiplex Rapid Diagnostic Pneumonia Panel Testing in Critically-ill Patients With Severe Hospital-acquired Pneumonia, Ventilator-associated Pneumonia and Community-acquired Pneumonia With High Risk of Multidrug Resistant Pathogen
The objective of the research is to ascertain the influence of a syndromic mutiplex PCR assay (FilmArray) on the management of patients hospitalised in the ICU for severe respiratory disease.
- Conditions
- Infectious Disease of Lung, Molecular Diagnosis, Pneumonia
- Trial name
- NCT06782607
- Testing
- Pneumonia Panel by FilmArray
- Where
- Thailand
- Volunteers
- 80 people
- Sponsor
- Mahidol University
Community-Acquired Pneumonia (CAP)
Lefamulin Post-Market Surveillance Study
Community-acquired pneumonia (CAP) refers to infectious parenchymal lung inflammation acquired outside hospital settings. In China, its incidence is 7.13 per 1000 person-years, with over 10 million new cases annually.
- Trial name
- NCT07697885
- Testing
- This is a multicenter, single-arm, non-interventional study. No interventional measures will be adopted.
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Marubeni Pharmaceuticals (Suzhou) Co., Ltd.
Covid-19, Critical Illness
Understanding Community Considerations, Opinions, Values, Impacts, and Decisions for COVID-19
The novel coronavirus (COVID-19) is affecting the way many people live their lives, including seeking medical care and maintaining good self-care to keep healthy.
- Conditions
- Covid-19, Critical Illness, Attitude of Health Personnel, Attitude to Health
- Trial name
- UC-COVID (NCT04373135)
- Testing
- Brief educational video
- Where
- United States
- Volunteers
- 1,971 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Community Acquired Pneumonia
Comparative Study of NXL103 Versus Comparator in Adults With Community Acquired Pneumonia
The purpose of this study is to compare the efficacy, safety and tolerance of 2 different dose levels of oral NXL103 with oral comparator in the treatment of community acquired pneumonia in adults
- Trial name
- NCT00653172
- Testing
- NXL103, comparator
- Where
- 60 sites in Chile, Croatia and 7 more
- Volunteers
- 302 people
- Sponsor
- Novexel Inc