Clinical trials: Community-based
Psychological Well-Being, Mental Health
An Audiobook-based Intervention on Community-dwelling Older Adults
The goal of this quasiexperimental study is to assess the impact of an audiobook mobile application on the well-being perception of older adults belonging to a Community Rehabilitation Center (CRC) at Concepcion, Chile.
- Trial name
- NCT05891925
- Testing
- Audiobook App
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad Católica de la Santísima Concepción
Cardiovascular Primary Prevention Strategy
Role of Screening With Coronary Computed Tomography Angiography in Primary Prevention of Coronary Heart Disease
The primary objective of this study is to determine whether coronary computed tomography angiography (CCTA) -based coronary heart disease(CHD) prevention strategy will be superior to traditional CHD prevention strategy, in…
- Trial name
- RESPECT (NCT05431309)
- Testing
- Coronary Computed Tomography Angiography, Standard Treatment
- Volunteers
- 15,000 people
- Sponsor
- Jinling Hospital, China
Brain Injuries
Behavioral Trial Studying Programmed Training to Improve Advocacy Skills for Individuals With Traumatic Brain Injury
The Midwest Advocacy Project (MAP) is a community-based multiple-site randomized practical behavioral trial of advocacy skill training for individuals with traumatic brain injury (TBI), their families, and significant others.
- Trial name
- MAP (NCT01002677)
- Testing
- Advocacy training curriculum, Self-directed
- Where
- 3 sites in United States
- Volunteers
- 234 people
- Sponsor
- Mayo Clinic
Cognitive Decline, Aging
Effects of Comprehensive Community Support Programs on Cognitive Function and Quality of Life in Older Adults
This prospective observational study aims to investigate the effects of a multidomain community-based support program on cognitive function and quality of life in older adults attending the Vefahane Life Center in Istanbul…
- Conditions
- Cognitive Decline, Aging, Quality of Life
- Trial name
- NCT07610109
- Testing
- Multidomain Community Support Program
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Istanbul Medipol University Hospital
Cancer, End Stage Cancer
Community Health Worker Based Intervention to Improve Palliative Care
The study aims to find out if community health worker (CHW) support will improve palliative care outcomes in African American patients with advanced cancer, by comparing the quality of life of patients who are receiving standard…
- Conditions
- Cancer, End Stage Cancer, Malignancy, Advanced Cancer
- Trial name
- DeCIDE PC (NCT05407844)
- Testing
- Community Health Worker (CHW) based palliative care
- Where
- 4 sites in United States
- Volunteers
- 160 people
- Sponsor
- Wake Forest University Health Sciences
Oral Neoplasm
Early Prediction of Oral Cancer by S100A7 Immunohistochemistry Signature-based Assessment
The purpose of this observational study is to evaluate the utility of the S100A7 immunohistochemistry signature-based assessment - STRATICYTE - in determining the risk of progression to cancer of clinically suspicious oral…
- Trial name
- NCT04622462
- Testing
- Standard of Care Histopathology, STRATICYTE Assessment
- Where
- 3 sites in Canada
- Volunteers
- 500 people
- Sponsor
- Proteocyte Diagnostics Inc.
Diabetes Mellitus, Type 1, Type 1 Diabetes
Feasibility of Closed-loop Automated Insulin Delivery System by Primary Care & Endocrinology, in Person & Via Telehealth
This is a study assessing the feasibility of using the insulin-only configuration of the iLet bionic pancreas with initiation in pump-naïve people with type 1 diabetes in a primary care practice with either in-person training and…
- Conditions
- Diabetes Mellitus, Type 1, Type 1 Diabetes, Diabetes, Autoimmune, Diabetes type1
- Trial name
- NCT05168657
- Testing
- Bionic Pancreas, Usual Care
- Where
- 2 sites in United States
- Volunteers
- 54 people
- Sponsor
- University of Colorado, Denver
Chronic Heart Failure, Diabetes Mellitus
Exploring Acceptance and Outcomes of an Online-based Self-management Support System in Chronic Illness
The aim of the USECARE project is to improve and test SENACA, an ICT-based self-management support system for chronically ill patients and informal caregivers. 60 end-users will be instructed to use SENACA for approx.
- Conditions
- Chronic Heart Failure, Diabetes Mellitus, Chronic Obstructive Pulmonary Disease, Special Orthopaedic Co-Morbidity After Hip/Knee Replacement
- Trial name
- USECARE (NCT02832739)
- Testing
- SENACA - ICT based self-management support system
- Where
- 2 sites in Israel, Norway
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Assuta Medical Center
Malaria, Pneumonia
Assessment of Use of Rapid Diagnostic Testing in the Context of Home Management With ACTs
This study is to assess the value of incorporating a malaria RDT based strategy in HMM. The primary activity of the study wil be a two armed cluster randomised trial in two study sites in Uganda, one in Ghana and one in Burkina…
- Trial name
- NCT00720811
- Testing
- Artemether-lumefantrine combination, amoxycillin, paracetamol
- Where
- 4 sites in Burkina Faso, Ghana and 1 more
- Volunteers
- 6,456 people
- Sponsor
- Mbarara University of Science and Technology
Smoking
Building a Community-based Network to Promote Smoking Cessation
This study describes the development of a community-based network to promote smoking cessation among female smokers in Hong Kong.
- Trial name
- NCT02968199
- Testing
- A brief intervention
- Where
- China
- Volunteers
- 457 people
- Sponsor
- The University of Hong Kong
Bacterial Infection, Sepsis
Efficacy Study of Community-Based Treatment of Serious Bacterial Infections in Young Infants
Approximately one-third of neonatal deaths in developing countries are due to infections acquired through the birth canal and/or exposure to an unclean environment soon after birth.
- Conditions
- Bacterial Infection, Sepsis, Infant, Newborn
- Trial name
- NCT00189384
- Testing
- ceftriaxone, procaine penicillin and gentamicin, oral cotrimoxazole and gentamicin
- Where
- Pakistan
- Volunteers
- 426 people
- Sponsor
- Aga Khan University
Cervical Cancer
Community Outreach-based Study to Increase Cervical Cancer Screening Among Hispanic Women in Cleveland
This study offers Hispanic women who are eligible for cervical cancer screening residing in the Cleveland metropolitan area one of two possible community outreach-based cervical cancer screening modalities, self-collection home…
- Trial name
- NCT05470309
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- MetroHealth Medical Center
Homeless Persons
Effect of a Rent Subsidy and Mentoring on Youth Transitioning Out of Homelessness
Compared to the vast amount of literature about the risk factors associated with young people entering and becoming entrenched in homelessness, much less is known about how to facilitate and sustain transitions off the streets.
- Trial name
- NCT03779204
- Testing
- Mentorship, Rent Subsidies
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Breast Carcinoma, Cervical Carcinoma
CATCH-UP Intervention in Increasing Cancer Screening and Prevention Care in Uninsured Patients at Community Health Centers
This randomized research trial studies the Community-based Health Information Technology (HIT) Tools for Cancer Screening and Health Insurance Promotion (CATCH-UP) intervention in increasing cancer screening and prevention care…
- Conditions
- Breast Carcinoma, Cervical Carcinoma, Colorectal Carcinoma, Health Status Unknown
- Trial name
- NCT02355262
- Testing
- Informational Intervention
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- OHSU Knight Cancer Institute
Pre-Exposure Prophylaxis (PrEP), HIV
Peer-led Community-based PrEP Delivery Among Youth in Brazil
The goal of this project is to conduct a series of studies to refine, test, and understand experiences with a peer-led community-based intervention in which youth will be integrated into health care teams and trained to deliver…
- Trial name
- COMPrEP (NCT06661356)
- Testing
- COMPrEP
- Where
- 2 sites in Brazil
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Falls, Falls Injury
EXpress Prevent Rural oldEr Adults' fallS, fractureS and Dependency (EXPRESS)
Falls are the leading cause of injury-related death among individuals aged 65 and above in China. The incidence of falls shows a significant urban-rural disparity in China, with rural areas experiencing a markedly higher rate…
- Conditions
- Falls, Falls Injury, Fall Prevention
- Trial name
- EXPRESS (NCT06984978)
- Testing
- AI-assisted, village doctors and express services-involved personalized fall prevention strategy
- Where
- China
- Volunteers
- 1,881 people, healthy volunteers welcome
- Sponsor
- Peking University
Substance Dependence, HIV (Human Immunodeficiency Virus)
Pre-exposure Prophylaxis (PrEP) for Health
This randomized controlled trial will test the efficacy of "PrEP for Health," a behavioral intervention to improve the use of antiretroviral pre-exposure prophylaxis (PrEP) among at-risk people who inject drugs (PWID) in two…
- Trial name
- PrEP (NCT04430257)
- Testing
- HIV and PrEP education, Motivational interviewing, Problem-solving and planning
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Brown University
Health-Related Quality-of-Life, Social Capital
Cocreating Action to Improve Rationality in the Health System
Despite widespread recognition of social, economic, or environmental health determinants, health action remains heavily dominated by individual-level solutions (e.g., medication, patient counselling, vaccination).
- Conditions
- Health-Related Quality-of-Life, Social Capital, Health Literacy, Community Based Participatory Research
- Trial name
- CAIR (NCT07237971)
- Testing
- Cocreation process
- Where
- 2 sites in Spain
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Universidad Miguel Hernandez de Elche
Maternal Distress, Perinatal Depression
A Common Elements-based Intervention to Improve Maternal Psychological Well-being and Mother-infant Interaction
Background: Millions of children in low resource settings are at high risk of poor development due to factors such as undernutrition, inadequate stimulation and maternal depression.
- Conditions
- Maternal Distress, Perinatal Depression, Development Delay, Language Delay
- Trial name
- NCT04252807
- Testing
- Intervention arm, Treatment as Usual
- Where
- Pakistan
- Volunteers
- 250 people
- Sponsor
- Human Development Research Foundation, Pakistan
Schizophrenia, Bipolar Disorder
Person-Centered Versus Measurement-Based Care in Mental Health
Fifteen minutes is the typical length of an outpatient medication management appointment for people with serious mental health conditions.
- Conditions
- Schizophrenia, Bipolar Disorder, Major Depression
- Trial name
- PCORI-SDM (NCT02507349)
- Testing
- Person-Centered Care, Measurement-Based Care
- Where
- 2 sites in United States
- Volunteers
- 2,443 people
- Sponsor
- University of Pittsburgh
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