Clinical trials: Comorbidities and Coexisting Conditions
Chronic Obstructive Lung Disease, Acute Exacerbation of COPD
Are Comorbidities Related to Frequent Severe Exacerbations of AECOPD
INTRODUCTION: Relationship between comorbidities and COPD is two-sided. While the number of comorbidities increasing, the frequency of acute exacerbations of COPD (AECOPD) is increasing, too.
- Conditions
- Chronic Obstructive Lung Disease, Acute Exacerbation of COPD, Comorbidities and Coexisting Conditions
- Trial name
- NCT05504993
- Testing
- Frequency of AECOPD
- Where
- Turkey (Türkiye)
- Volunteers
- 92 people
- Sponsor
- Ankara University
Comorbidities and Coexisting Conditions
Evaluation of a Personalized Care Management Program for High Hospital Utilizers
This randomized clinical trial intends to evaluate the effectiveness of enrollment in Atrium Health's Multiple Visit Patient (MVP) care management program compared to usual care on reducing 12-month total inpatient hospital…
- Trial name
- NCT04727567
- Where
- United States
- Volunteers
- 454 people
- Sponsor
- Wake Forest University Health Sciences
Interstitial Lung Disease, Comorbidities and Coexisting Conditions
Taiwan Interstitial Lung Disease Multi-center Investigation and Registry
The Taiwan Interstitial Lung Disease (ILD) Multi-center Investigation and Registry aims to evaluate the long-term outcomes of patients with fibrotic interstitial lung disease.
- Conditions
- Interstitial Lung Disease, Comorbidities and Coexisting Conditions, Pulmonary Arterial Hypertension, Treatment Adherence
- Trial name
- TAILI (NCT06476470)
- Where
- Taiwan
- Volunteers
- 10,000 people
- Sponsor
- Taichung Veterans General Hospital
Exercise, Sedentary Behavior
Association of a Digital Signature of Physical Activity and Sedentary Lifestyle With the Development of Multimorbidities in Chronic Diseases (eMOB)
Physical activity (PA) and sedentary lifestyle are determinants in the development of chronic diseases and associated quality of life alterations.
- Conditions
- Exercise, Sedentary Behavior, Non Communicable Diseases, Comorbidities and Coexisting Conditions
- Trial name
- eMOB (NCT05578495)
- Testing
- Accelerometer data
- Where
- France
- Volunteers
- 700 people
- Sponsor
- University Hospital, Clermont-Ferrand
Multimorbidity, Polypharmacy
MultiPAP Plus: Improving Prescription in Primary Care Patients With Multimorbidity and Polypharmacy
This study assesses the effectiveness of a complex intervention in young-old patients with multimorbidity and polypharmacy aimed at improving physician drug prescription in primary care, measured by hospitalization-mortality at…
- Conditions
- Multimorbidity, Polypharmacy, Comorbidities and Coexisting Conditions, Clinical Decision-Support Systems
- Trial name
- MultiPAP Plus (NCT04147130)
- Testing
- MultiPAP Plus, Usual care
- Where
- 3 sites in Spain
- Volunteers
- 1,162 people
- Sponsor
- Instituto Aragones de Ciencias de la Salud
Intermittent Fasting, Obesity, Morbid
Intermittent Fasting as a Means to Lose Fluid Overload and Weight in Complicated Obesity
To examine the feasibility of intermittent fasting (36h, twice a week, unlimited salt and calorie-free fluid consumption), over three months, on body weight and composition in complicated obesity in whom age and medical…
- Conditions
- Intermittent Fasting, Obesity, Morbid, Comorbidities and Coexisting Conditions, Weight Loss
- Trial name
- NCT04193995
- Testing
- Intermittent fasting
- Where
- Israel
- Volunteers
- 15 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Hypertension, Diabetes Mellitus, Type 1
Community Models for Hypertension and Diabetes Care for Refugees
The project will investigate and improve a community health worker (CHW) based model for non-communicable disease (NCD) care in a humanitarian emergency.
- Conditions
- Hypertension, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Comorbidities and Coexisting Conditions
- Trial name
- NCT04229667
- Testing
- Improved Community Health Volunteer (CHV) program
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- International Rescue Committee
Type 2 Diabetes, Comorbidities and Coexisting Conditions
Wearable Technology and a Virtual Lifestyle Program for Type 2 Diabetics
The Primary Care Diabetes Support Program (PCDSP) offers a lifestyle medicine program, STAND, that patients can self-select themselves to participate. STAND offers biweekly, one-hour educational classes.
- Trial name
- STAND-VAT (NCT04498819)
- Testing
- Wearable Activity Trackers, Exercise Prescription and Virtual Care
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Western University, Canada
Back Pain, Low Back Pain
Are Multimorbidity and Related Factors Associated With Non-response Bias in Patients With Spinal Pain?
The study aims to explore if non-response bias exists among individuals with chronic back pain, focusing on the impact of chronic disease count, treatment burden from multimorbidity, and health-related quality of life.
- Conditions
- Back Pain, Low Back Pain, Neck Pain, Comorbidities and Coexisting Conditions
- Trial name
- NCT06333847
- Where
- Denmark
- Volunteers
- 360 people
- Sponsor
- Jacob Christiansen Gandløse
Chronic Obstructive Pulmonary Disease, Comorbidities and Coexisting Conditions
Xishui Project for IDM of COPD and Comorbidities
Study Population: 4000 stable COPD patients, and among them approximately 2000 subjects with hypertension and/or type 2 diabetes complications.
- Trial name
- NCT06456749
- Testing
- Integrated Disease Management
- Volunteers
- 4,000 people
- Sponsor
- China-Japan Friendship Hospital
Diabetes Mellitus, Type 1, Obesity, Childhood
Family-Based Treatment for Type 1 Diabetes
Type 1 Diabetes carries high burden for affected youth and their families. Advances in insulin therapy and technology have been associated with increased obesity with 1/3 adolescents being overweight/obese.
- Conditions
- Diabetes Mellitus, Type 1, Obesity, Childhood, Overweight, Comorbidities and Coexisting Conditions
- Trial name
- FBTT1D (NCT05756361)
- Testing
- Family-Based Treatment for T1D
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- State University of New York at Buffalo
Heart Failure With Preserved Ejection Fraction, Arterial Hypertension
Ambulatory Blood Pressure in HFPEF Outcomes Global Registry
Heart failure and preserved ejection fraction (HFPEF) is a disease with increasing prevalence world wide. Due to its etiological and prognostic relationship with hypertension, it is highly interesting to know the characteristics…
- Conditions
- Heart Failure With Preserved Ejection Fraction, Arterial Hypertension, Frailty Syndrome, Comorbidities and Coexisting Conditions
- Trial name
- HFPEFGlobal (NCT04065620)
- Testing
- ambulatory blood pressure measurement
- Where
- Spain
- Volunteers
- 5,000 people
- Sponsor
- Hospital Clinic of Barcelona
Diabetes Mellitus, Hypertension
An International Prospective, Observational, Multi-centre Study on the Duration of Pre-operative Liquid Fasting
The investigators will be performing an international prospective, observational, multi-centre, cross-sectional study to determine the actual duration of preoperative liquid fasting time in European patients.
- Conditions
- Diabetes Mellitus, Hypertension, Ischaemic Heart Disease, Comorbidities and Coexisting Conditions
- Trial name
- THIRST (NCT06527703)
- Testing
- no intervention
- Where
- Malta
- Volunteers
- 5,100 people, healthy volunteers welcome
- Sponsor
- Mater Dei Hospital, Malta
Sleep Apnea, Sleep Bruxism
Impact of Bruxism Related Arousals on Cardiovascular Risk in Co-morbid Insomnia and Sleep Apnea
Sleep disordered breathing is a common and serious health problem. According to epidemiological data, it may affect about 20% of adult population. The majority is not aware of the disease.
- Conditions
- Sleep Apnea, Sleep Bruxism, Sleep Disorder, Insomnia
- Trial name
- NCT04937036
- Testing
- Polysomnography
- Where
- Poland
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Pregnancy, Smoking Behavior
HISTOLOGICAL RESULTS IN TRANSGENDER INDIVIDUALS ASSIGNED TO FEMALES AT BIRTH UNDERGOING GENDER AFFIRMATION SURGERY AND IN TESTOSTERONE THERAPY
The aim of this study is to report histological results of genital organs removed during gender affirmg surgery in transgender people assigned female at birth (AFAB), to increase the knowledge about the long-term effects of…
- Conditions
- Pregnancy, Smoking Behavior, Testosterone Replacement Therapy, Drugs
- Trial name
- NCT06710496
- Testing
- analysis of medical records
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Pulmonary Disease, Chronic Obstructive, Exacerbation Copd
REal-time Data Monitoring for Shared Adaptive, Multi-domain and Personalised Prediction and Decision Making for Long-term Pulmonary Care Ecosystems (RE-SAMPLE)
The main objective of this RE-SAMPLE cohort study is to identify from a real-world data (RWD) set that will be collected, a subset of data that can be potentially used as important predictors and parameters for disease…
- Conditions
- Pulmonary Disease, Chronic Obstructive, Exacerbation Copd, Comorbidities and Coexisting Conditions
- Trial name
- RE-SAMPLE (NCT04955080)
- Where
- Netherlands
- Volunteers
- 216 people
- Sponsor
- Medisch Spectrum Twente
Comorbidities and Coexisting Conditions, Healthy
Immune Response of an Interchangeable Booster Vaccine Against COVID-19 Among Individuals With Risk Factors for Severity
Experimental, single-arm study in participants with comorbidities, previously immunized with 2 doses of CoronaVac, who will receive a booster vaccine with 1 dose of the Oxford/AstraZeneca vaccine.
- Trial name
- COVACManaus2 (NCT05289206)
- Testing
- Vaccine - ChAdOx1-S/nCoV-19 [recombinant]
- Where
- Brazil
- Volunteers
- 4,446 people, healthy volunteers welcome
- Sponsor
- Fundação de Medicina Tropical Dr. Heitor Vieira Dourado
Postoperative Complications, Comorbidities and Coexisting Conditions
Study of Direct Admission of Postoperative Patients to ICU
Background: This study assessed perioperative factors associated with planned and unplanned postoperative ICU admission and evaluated the outcome of the two groups. There are limited researches evaluating these factors.
- Trial name
- NCT04680208
- Testing
- Surgical procedure under anesthesia
- Where
- Oman
- Volunteers
- 68 people
- Sponsor
- Sultan Qaboos University
Comorbidities and Coexisting Conditions, Social Isolation
The PREPARE for COVID Trial
This is a randomized trial of home-based exercises versus control for older adults during the COVID-19 pandemic. The hypothesis is that participation in a home-based program will reduce the risk of adverse effects of physical…
- Trial name
- NCT04392115
- Testing
- The PREPARE program
- Volunteers
- 372 people
- Sponsor
- Ottawa Hospital Research Institute
Asthma, Breast Neoplasms
Digital Tool Enhancing GPs' Information Management for Patients with Multimorbidity - a Pilot Study
The gp-multitool.de study is a cluster-randomized controlled trial that aims to enhance evidence-based and patient-centered care for patients with multimorbidity by assessing and providing information relevant for the primary…
- Conditions
- Asthma, Breast Neoplasms, Coronary Disease, Diabetes Mellitus, Type 1
- Trial name
- gp-multitool (NCT06061172)
- Testing
- gp-multitool.de
- Where
- Germany
- Volunteers
- 123 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf