Clinical trials: Comorbidity
Asthma, Asthma in Children
Allergy, Asthma, and Atopic Eczema in Finland
The summary is available at --> https://www.finnatopy.fi/summary
- Conditions
- Asthma, Asthma in Children, Allergy, Rhinitis, Allergic
- Trial name
- FinnATOPY (NCT06330974)
- Testing
- No intervention, No Intervention: Observational Cohort
- Where
- Finland
- Volunteers
- 1,200,000 people
- Sponsor
- Tampere University
HIV
HIV Infection and Risk Related Coinfections/Comorbidities in Indonesia
INA-PROACTIVE is a multicenter, prospective, observational cohort study of HIV positive antiretroviral-naïve and treatment-experienced individuals. No investigational treatment or intervention will be used by this study.
- Trial name
- INAPROACTIVE (NCT03663920)
- Where
- 19 sites in Indonesia
- Volunteers
- 4,336 people
- Sponsor
- Ina-Respond
HIV/AIDS, Dysglycemia
Alcohol & Metabolic Comorbidities in PLWHA: Evidence Driven Interventions
Cross-sectional and prospective studies are proposed to test the prediction that a higher proportion of HIV+ individuals with hazardous alcohol drinking with subclinical fasting dysglycemia will present with impaired oral glucose…
- Conditions
- HIV/AIDS, Dysglycemia, Alcohol Use Disorder
- Trial name
- ALIVE-Ex (NCT03299205)
- Testing
- Exercise
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
COVID-19
Clinical Study for the Efficacy and Safety of Ropeginterferon Alfa-2b in Adult COVID-19 Patients With Comorbidities
To evaluate the efficacy of subcutaneous ropeginterferon alfa 2b ( P1101 combined with standard of care (SOC) compared with standard care alone in adult COVID-19 patients with comorbidities.
- Trial name
- NCT05808322
- Testing
- Ropeginterferon alfa-2b, SOC
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Obesity, Overweight
Efficacy and Safety of Ribupatide in Participants Living With Obesity or Overweight With Weight-Related Comorbidities Who Do Not Have Diabetes
The primary objective of the study is to determine the effects of ribupatide (KAI-9531) subcutaneous (SC) injection once weekly compared to placebo on percent change in body weight.
- Trial name
- KaiNETIC-1 (NCT07284875)
- Testing
- Ribupatide
- Where
- 110 sites in United States, Argentina and 8 more
- Volunteers
- 2,530 people
- Sponsor
- Kailera
Scoliosis Idiopathic, Myopia
Zhejiang Adolescent Spine and Vision Health Cohort: A Longitudinal Database Analysis
The aim of study: 1. To investigate the prevalence of scoliosis, other spinal deformities, myopia, and visual impairments in adolescents (aged 6-18) in Zhejiang Province.
- Conditions
- Scoliosis Idiopathic, Myopia, Vision Disorders
- Trial name
- NCT06992622
- Where
- China
- Volunteers
- 73,000 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Multiple Sclerosis, Relapsing-Remitting
Physical Activity, Sedentary Behaviour and Cardiometabolic Health in Multiple Sclerosis
This study evaluates the association between sedentary behaviour, physical activity, and the cardiometabolic health of Multiple Sclerosis via several cardiovascular, metabolic and anthropometric parameters.
- Trial name
- NCT05752630
- Where
- Belgium
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Rheumatoid Arthritis (RA, Oxidative Stress
Oxidative Stress and Cardiovascular Risk in Patients With Rheumatoid Arthritis
The pathogenic process underlying atherosclerosis resembles a chronic inflammatory response in which oxidative stress is involved.
- Conditions
- Rheumatoid Arthritis (RA, Oxidative Stress, Cardiovascular (CV) Risk
- Trial name
- PIFIISC23/07 (NCT07760662)
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- University of La Laguna
Obstructive Sleep Apnea Syndrome
Diagnosis of Patients With Low or Intermediate Suspicion of SAHS or With Comorbidity: Standard Laboratory Polysomnography Compared With Three Nights of Home Respiratory Polygraphy.
Study Objectives: Obstructive sleep apnea (OSA) diagnosis using simplified methods such as home respiratory polygraphy (HRP) is only recommended in patients with a high pre-test probability.
- Trial name
- NCT01820156
- Testing
- Home Respiratory Polygraphy, Standard Polysomnography
- Where
- Spain
- Volunteers
- 56 people
- Sponsor
- Hospital Clinic of Barcelona
Obesity, Memory Deficits
Obesity and Memory, mRNA, Body Composition, Comorbidity Scale
1. Briefly describe the purpose of this protocol. First purpose of the study is to understand the inheritance of morbid obesity. 2. Briefly summarize how participants are recruited.
- Trial name
- 2a (NCT00531505)
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Oregon Health and Science University
Human Immunodeficiency Virus, Depression
Addressing Psychosocial Comorbidities in HIV Treatment and Prevention
Project AProaCH is an open pilot trial of a cognitive behavioral therapy (CBT) for individuals with HIV with various psychological comorbidities, which the investigators call "syndemics".
- Conditions
- Human Immunodeficiency Virus, Depression, Mental Health
- Trial name
- APPROACH (NCT02696681)
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Miami
Galectin-3 and Pemphigus
Evaluation of Galectin-3 in Serum and Saliva of Pemphigus Patients
Assessment of the expression of galectin-3 in serum and saliva of pemphigus patients and compare it with age and sex matched controls.
- Trial name
- NCT05992727
- Testing
- Galectin 3 measurement in serum and saliva by ELIZA
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Obesity
Effects of OAGB and DJB-SG on 10-year and Lifetime Risks of MACE
Metabolic bariatric surgery (MBS) has demonstrated its efficacy in achieving sustainable weight loss and alleviating associated comorbidities.
- Trial name
- NCT06254339
- Testing
- OAGB, DJB-SG
- Volunteers
- 830 people
- Sponsor
- National Defense Medical Center, Taiwan
Chronic Obstructive Pulmonary Disease (COPD), Severe Asthma
COINCIDE: Cardineurovascular dIsease and Obstructive Airway Disease
Patients with chronic obstructive pulmonary disease (COPD) and severe asthma frequently present with cardiovascular comorbidities that contribute substantially to morbidity and mortality.
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Severe Asthma, Cardiovascular Diseases
- Trial name
- COINCIDE (NCT07856667)
- Testing
- Routine Clinical Care
- Volunteers
- 350 people
- Sponsor
- VASCage GmbH
Chronic Kidney Diseases
Telemedicine for Home-based Management of Patients With Chronic Kidney Diseases and Comorbidities (NET-2018-12367206)
This project is aimed to analyze the current models and to design innovative strategies to improve quality of care and optimise resource utilization of telemedicine (TM) in home-based management for the global care of patients…
- Trial name
- Telemechron (NCT05906927)
- Where
- Italy
- Volunteers
- 8 people
- Sponsor
- Azienda USL Toscana Nord Ovest
Multiple Chronic Conditions, Diabetes Mellitus
ACHRU Community Partnership Program for Diabetes Self-Management for Older Adults - Canada
Living with diabetes and other chronic (ongoing) conditions is common in older adults. These individuals have poorer health and higher use of health services compared to older adults with diabetes alone.
- Trial name
- ACHRU-CPP (NCT03664583)
- Testing
- ACHRU-Community Partnership Program (CPP)
- Where
- 4 sites in Canada
- Volunteers
- 295 people
- Sponsor
- McMaster University
Obesity
Rimonabant in Obesity Over a 2-Year Duration (RIO-Europe)
The primary objective was to assess the effect of SR141716 on weight loss and weight maintenance over a period of one year when prescribed with a hypocaloric diet in obese patients with or without comorbidities.
- Trial name
- NCT00386061
- Testing
- rimonabant (SR141716)
- Where
- 7 sites in United States, Belgium and 5 more
- Volunteers
- 1,507 people
- Sponsor
- Sanofi
Pathological or "at Risk" Gambling
Transversal Multiaxial Evaluation and 5-year Follow-up of a Cohort of French Gamblers (JEU)
This study is divided into two stages. The first stage is a transversal study and corresponds to the recruitment of participants, which will last about two years.
- Trial name
- NCT01207674
- Testing
- Summons of patients and filling questionnaire
- Where
- 7 sites in France
- Volunteers
- 641 people
- Sponsor
- Nantes University Hospital
Obesity, Morbid Obesity
Monitoring Obese Patients : Impact on the Frequency of Monitoring Weight
The literature data show that long-term monitoring has an effect on weight loss, comorbidity and on improving the quality of life.
- Conditions
- Obesity, Morbid Obesity, Quality of Life
- Trial name
- SUIVIOBESITE (NCT02374866)
- Testing
- closer monitoring
- Where
- France
- Volunteers
- 96 people
- Sponsor
- University Hospital, Limoges
Interdisciplinary Communication, Postoperative Complications
Effects of Preoperative Multidisciplinary Team Meetings for High-risk, Adult, Noncardiac Surgical Patients
The current multicenter stepped wedge randomized cluster trial study aims to assess whether implementation of preoperative multidisciplinary team (MDT) discussions is (cost)effective for high risk noncardiac surgical patients.
- Conditions
- Interdisciplinary Communication, Postoperative Complications, Noncardiac Surgery, Surgical Procedures, Operative
- Trial name
- PREPARATION (NCT05703230)
- Testing
- Structured preoperative multidisciplinary team meeting
- Where
- 14 sites in Netherlands
- Volunteers
- 1,200 people
- Sponsor
- Rijnstate Hospital