Clinical trials: Comparison of the Efficacy
Post Traumatic Stress Disorder
Electrical Vestibular Nerve Stimulation (VeNS) as a Treatment for PTSD
Trial title: A Randomized, Double Blind Sham Controlled Clinical Trial to Evaluate the Efficacy of Electrical Vestibular Nerve Stimulation (VeNS), Compared to a Sham Control for Treatment of PTSD The aim of this study: To better…
- Trial name
- NCT05242367
- Testing
- Modius Spero active device
- Where
- United States
- Volunteers
- 383 people
- Sponsor
- Neurovalens Ltd.
Myopia
To Evaluate the Effectiveness of New Specially Designed Fitlens Soft Lens.
Myopia is a common disorder, affecting approximately one-third of the US population and over 90% of the population in some East Asian countries.
- Trial name
- NCT05433792
- Testing
- Myolens CN (Central-Near) soft contact lens, MiSight® soft contact lens
- Where
- Israel
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Fitlens Ltd.
Aging Problems, Wrinkle
Comparing Polydioxanone Thread Embedding Acupuncture and Manual Acupuncture for Nasolabial Fold Reduction
This study was aimed to compare the effectiveness of polydioxanone thread embedding acupuncture and manual acupuncture on the reduction of the nasolabial fold.
- Trial name
- NCT05098912
- Testing
- Manual acupuncture, Thread embedding acupuncture
- Where
- Indonesia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Foot Pain
Reducing Foot Pain and Peak Plantar Pressure in Patients With Foot Pain
The research project aims to evaluate the effectiveness of OrthoFeet Hands-Free therapeutic shoes and prefabricated inserts in patients with foot pain.
- Trial name
- NCT06516900
- Testing
- OrthoFeet HandsFree Therapeutic Shoe
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Texas Rio Grande Valley
Respiratory Tract Infections, Fever
Placebo and Active Controlled Study to Compare the Antipyretic Efficacy of Aspirin® in Patients With Acute Febrile Upper Respiratory Tract Infections Suspected to be of Viral Origin
This study is addressed to patients suffering from an acute febrile upper respiratory tract infection suspected to be of viral origin.
- Trial name
- NCT01464944
- Testing
- Acetylsalicylic acid (Aspirin, BAYE4465), Paracetamol
- Where
- 9 sites in Russia, Ukraine
- Volunteers
- 392 people
- Sponsor
- Bayer
Diabetes, Diabetes Mellitus, Type 2
Comparison of NN1250 Versus Insulin Glargine in Subjects With Type 2 Diabetes
This trial is conducted in Europe and the United States of America (USA). The aim of this trial is to compare NN1250 (insulin degludec (IDeg)) with insulin glargine (IGlar) in subjects with type 2 diabetes never treated with…
- Trial name
- BEGIN™ (NCT00982644)
- Testing
- insulin degludec, insulin glargine
- Where
- 187 sites in United States, Austria and 13 more
- Volunteers
- 1,030 people
- Sponsor
- Novo Nordisk A/S
Low Back Pain
Comparison of BTDS (Buprenorphine Transdermal System) and Placebo in Low Back Pain
The primary objective of this study is to evaluate the efficacy and safety of BTDS compared to placebo in subjects with moderate to severe low back pain.
- Trial name
- NCT00346047
- Testing
- Buprenorphine Transdermal System
- Where
- 29 sites in Japan
- Volunteers
- 238 people
- Sponsor
- Mundipharma K.K.
Bilateral Blepharitis (Disorder)
To Compare Blephapad Combo vs Standard Treatment for Eyelid Cleansing in Bilateral Posterior Blepharitis
The purpose of this study is to evaluate the efficacy of, and patient satisfaction with Blephapad Combo in the treatment of posterior blepharitis.
- Trial name
- NCT03301844
- Testing
- Blephapad Combo, Standard treatment
- Where
- Italy
- Volunteers
- 19 people
- Sponsor
- NTC srl
Active Systemic Lupus Erythematosus
Efficacy and Safety of Anifrolumab Compared to Placebo in Adult Subjects With Active Systemic Lupus Erythematosus
The purpose of this study is to evaluate the efficacy and safety of an intravenous treatment regimen of anifrolumab versus placebo in adult participants with moderately to severely active, autoantibody-positive systemic lupus…
- Trial name
- NCT02446899
- Testing
- Anifrolumab
- Where
- 113 sites in United States, Argentina and 13 more
- Volunteers
- 373 people
- Sponsor
- AstraZeneca
Diabetic Foot Infection
Safety and Efficacy Study of Contezolid Acefosamil and Contezolid Compared to Linezolid Administered Intravenously and Orally to Adults With Moderate or Severe Diabetic Foot Infections (DFI)
This is a Phase 3, multicenter, randomized, double-blind, safety and efficacy study of contezolid acefosamil (IV)/contezolid (PO) compared with linezolid (IV and PO) administered for a total of 14 to 28 days in adult subjects…
- Trial name
- NCT05369052
- Testing
- contezolid acefosamil (IV)/contezolid (PO), Linezolid (IV and PO)
- Where
- 14 sites in United States, Bulgaria and 6 more
- Volunteers
- 865 people
- Sponsor
- MicuRx
Diabetes Mellitus, Type 2
Efficacy and Safety of Exenatide Once Weekly Suspension in Subjects With Type 2 Diabetes
To compare the effect on glycemic control (HbA1c) of exenatide suspension administered once weekly to that achieved by exenatide administered twice daily for 28 weeks in subjects with type 2 diabetes mellitus.
- Trial name
- DURATION-NEO-1 (NCT01652716)
- Testing
- Exenatide once weekly suspension, Exenatide twice daily
- Where
- 58 sites in United States
- Volunteers
- 377 people
- Sponsor
- AstraZeneca
Plaque Psoriasis
Study Evaluation of the Efficacy, Safety and Immunogenicity of Adalimumab in Comparison With Humira®
MABPS-3/2020 is a double-blind randomized multicenter clinical trial comparing efficacy, immunogenicity and safety profiles of Adalimumab (manufactured by Mabscale, LLC) compared to Humira®.
- Trial name
- NCT06005532
- Testing
- Adalimumab, Humira
- Where
- 9 sites in Russia
- Volunteers
- 494 people
- Sponsor
- Mabscale, LLC
P. Falciparum Malaria
Compare the Effectiveness Between Existing Treatment and New Treatment
In camps for displaced persons located along the Thai-Myanmar border, mefloquine and artesunate combination therapy has been used since 1992.
- Trial name
- RDM (NCT01640587)
- Testing
- Mefloquine+Artesunate, Dihydroartemisinin-Piperaquine
- Where
- Thailand
- Volunteers
- 76 people
- Sponsor
- University of Oxford
Psoriasis (PsO)
Comparison of Otezla to SFA-002 to Placebo in Plaque Psoriasis Patients
The goal of this clinical trial] is to learn if SFA002 can treat mild, moderate and severe plaque psoriasis as good or better than Otezla, compared to placebo in adult and pediatric patients.
- Trial name
- NCT06863493
- Testing
- SFA002, Otezla
- Volunteers
- 125 people
- Sponsor
- SFA Therapeutics
HIV Infections
Comparative Efficacy and Safety Study of Dolutegravir and Lopinavir/Ritonavir in Second-line Treatment
For treatment of human immunodeficiency virus type 1(HIV-1), publicly funded programmes tend to follow World Health Organization (WHO) guidelines to use a non-nucleoside reverse transcriptase inhibitor (NNRTI) combined with two…
- Trial name
- NCT02227238
- Testing
- DTG, LPV/RTV, Two NRTIs
- Where
- 59 sites in Argentina, Brazil and 11 more
- Volunteers
- 627 people
- Sponsor
- ViiV Healthcare
Kidney Failure, Chronic, Anemia
A Study of the Safety and Efficacy of Long-term Correction of Anemia With Epoetin Alfa in Early Hemodialysis Patients
The purpose of this study in early hemodialysis patients (on dialysis 3 to 18 months) is to assess the effect of correction versus partial correction of anemia using epoetin alfa on heart pumping function.
- Trial name
- NCT00261521
- Testing
- epoetin alfa
- Volunteers
- 596 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Femur Neck Fracture, Spinal Anesthesia
Comparison of Unilateral Spinal Anesthesia and Nerve Block in Hip Fractures
This randomized study aims to compare the efficacy and hemodynamic effects of hypobaric unilateral spinal anesthesia (HUSA) and lumbar plexus block (LP-SP) in patients undergoing femoral neck fracture surgery.
- Conditions
- Femur Neck Fracture, Spinal Anesthesia, Lumbar Plexus Nerve Block
- Trial name
- NCT07272226
- Testing
- Hipobaric Unilateral Spinal Anesthesia Group, Lumbar Plexus Block (LP-SP)
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Coronary Artery Disease, Coronary Stenosis
Percutaneous Treatment of LONG Native Coronary Lesions With Drug-Eluting Stent-VII: Sirolimus-eluting (Ultimaster) vs. Everolimus-Eluting Stents (Xience)
This study compares angiographic and clinical outcomes in patients with long coronary lesions treated with sirolimus-eluting stent (Ultimaster stent) or everolimus-eluting stent (Xience Alpine stent).
- Trial name
- LONG-DES VII (NCT03484234)
- Testing
- Ultimaster stent, Xience alpine stent
- Where
- 2 sites in South Korea
- Volunteers
- 36 people
- Sponsor
- Seung-Jung Park
Gonarthrosis, Meniscus; Degeneration
Comparison of Ultrasound-Guided Perimeniscal Steroid and 5% Dextrose Injections in Knee Osteoarthritis
Introduction: The primary goal of treating knee osteoarthritis is to reduce pain and improve the patient's quality of life. Medial meniscal extrusion is a condition that is linked to pain and disability in knee osteoarthritis and…
- Conditions
- Gonarthrosis, Meniscus; Degeneration, Pain, Chronic
- Trial name
- NCT06308887
- Testing
- Triamcinolone Acetonide, Dextrose 5% in water
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Kastamonu University
Hypertension; Hypertrophy, Left Ventricular
Efficacy and Safety of Valsartan in Combination With Amlodipine Compared to Losartan Plus Hydrochlorothiazide in Patients With Hypertension and Left Ventricular Hypertrophy
This study will evaluate the safety and efficacy of amlodipine plus valsartan in patients with hypertension and left ventricular hypertrophy
- Trial name
- NCT00446563
- Testing
- Valsartan, Amlodipine, Hydrochlorothiazide
- Where
- Germany
- Volunteers
- 90 people
- Sponsor
- Novartis
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