Clinical trials: Compartment Syndrome
Acute Compartment Syndrome
Real-Time Muscle Pressure Measurements in Patients at Risk for Acute Compartment Syndrome
The purpose of this trial is to conduct a pilot study that will aid in the design of an evaluation of the clinical benefit of MY01, an FDA cleared device, that allows continuous monitoring of intracompartmental muscle pressure in…
- Trial name
- NCT04671173
- Testing
- Measurement of the Intra-Compartmental Pressure with the MY01 device
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Acute Pancreatitis, Intra-Abdominal Hypertension
Predictive Ability of Intra-Abdominal Pressure for Mortality in Patients With Severe Acute Pancreatitis
Severe Acute Pancreatitis (SAP) is an acute inflammatory condition of the pancreas characterized by organ dysfunction and increased mortality.
- Trial name
- NCT04525027
- Testing
- intra-abdominal pressure in severe acute pancreatitis
- Where
- India
- Volunteers
- 360 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Anterior Knee Pain Syndrome
In Vivo Arthroscopic Behavior of the Infrapatellar Plica of the Knee
Anterior knee pain has been an enigmatic problem for orthopedic surgeons. Recent studies, as well as the clinical observation of the principle investigator have suggested that arthroscopic resection of the infrapatellar plica…
- Trial name
- NCT00643487
- Testing
- observation of the behavior of the infrapatellar plica
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- State University of New York - Upstate Medical University
Abdominal Compartment Syndrome
Intraoperative Peak Airway Pressure Changes on Postoperative Pulmonary Function After Muscle Plication
An abdominal panniculus excision procedure is known as an abdominoplasty (panniculectomy). Musculofascial plication is a crucial aspect of abdominoplasty, especially for patients with significant divarication of the recti…
- Trial name
- NCT06291389
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Al-Azhar University
Compartment Syndrome of Leg
Effects of Perioperative Patient Education Regarding Compartment Syndrome on Post-operative Opioid Consumption
This study is a prospective, randomized trial. Our study aims to study the effects of perioperative patient education about compartment syndrome on patients' perception of their own pain, amount of opioid medication utilization…
- Trial name
- NCT03359031
- Testing
- Patient education
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- Rothman Institute Orthopaedics
Intra-Abdominal Hypertension
First-In-Human Study of PDT to Detect IAH
PDT is a continuous pressure monitoring for Intra-Abdominal hypertension (IAH) designed to be less invasive than pan-endoscopic evaluation, more tolerable than abdominal tapping, and more effective than intravesical pressure…
- Trial name
- NCT06333366
- Testing
- Intra-gastrointestinal monitoring device (PDT)
- Where
- Taiwan
- Volunteers
- 10 people
- Sponsor
- Chang Gung Memorial Hospital
Chronic Exertional Compartment Syndrome
Diagnosing Compartment Syndrome With SHAPE vs Elastography
Chronic exertional compartment syndrome (CECS) is an innocuous condition seen primarily in 10-60% of young active people with exercise induced leg pain.
- Trial name
- NCT05247541
- Testing
- Definity
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Traumatic Brain Injuries, Intracranial Hypertension
Effectiveness of Surgical Procedures for Acute Cranial Expansion in Traumatic Brain Injury
Traumatic brain injury (TBI) patients often exhibit an increase in their intracranial volume due to blood collection or brain tissue edema.
- Trial name
- E-SPACE-TBI (NCT06776614)
- Testing
- Decompressive Craniectomy, Expansion Craniotomy
- Volunteers
- 292 people
- Sponsor
- Meditech Foundation
Osteonecrosis, Pseudarthrosis
Musculoskeletal Non-tumoral Pathology Quantitative Perfusion
Study on quantitative perfusion parameters acquired on MR imaging of patients with non-tumoral pathology of the musculoskeletal system.
- Conditions
- Osteonecrosis, Pseudarthrosis, Compartment Syndrome
- Trial name
- AFRONT (NCT02683252)
- Testing
- T1 mapping and MR perfusion acquisition
- Where
- 2 sites in France
- Volunteers
- 400 people
- Sponsor
- Central Hospital, Nancy, France
Compartment Syndromes, Polytrauma
Non-invasive Limb Compartment Pressure Measurement
Compartment syndrome (CS) is a serious complication of soft-tissue injuries in patients with fractures of the musculoskeletal apparatus.
- Conditions
- Compartment Syndromes, Polytrauma, Burn Injury
- Trial name
- FNO-TRAUMA-CPM (NCT03730688)
- Testing
- Conventional compartment pressure measurement, Experimental compartment pressure measurement
- Where
- 2 sites in Czechia
- Volunteers
- 70 people
- Sponsor
- University Hospital Ostrava
HIV Infections
Body Compartment PK for New HIV Pre-exposure Prophylaxis Modalities
The purpose of this study is to determine the ability of new anti-HIV agents to penetrate different body compartments in HIV negative men who have sex with men and transgender women.
- Trial name
- NCT02985996
- Testing
- Truvada, Genvoya
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Emory University
Compartment Syndrome
Phase I, Arteriocyte Magellan MAR01 Therapy - Compartment Syndrome and Battlefield Trauma
Compartment syndrome (CS) is a condition resulting from increased pressure within a compartment, which compromises circulation and can lead to critical limb ischemia.
- Trial name
- Magellan MAR01 (NCT01837264)
- Testing
- Magellan®
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Arteriocyte, Inc.
Limb Ischemia, Compartment Syndrome of Leg
Chemical Analysis of Limb Microfluidics
Compartment syndrome (CS) is a condition where an increase in pressure in an anatomical compartment (e.g. the lower leg) affects the blood supply of the tissues, leading to tissue damage.
- Trial name
- CALM (NCT06050499)
- Testing
- Microdialysis catheter + biosensor
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- Imperial College London
Intra-Abdominal Hypertension, Abdominal Compartment Syndrome
Abdominal Compartment Syndrome : Diagnostic and Prognostic Value of CT Findings - a Prospective Study
Abdominal Compartment Syndrome (ACS) is a well known condition occuring in critically ill patients in intensive care units. This syndrome features a sustained intra abdominal hypertension (IAH) above 20 mmHg and a multiple organ…
- Trial name
- SCANAPIV (NCT02814734)
- Volunteers
- 140 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Nontraumatic Compartment Syndrome of Leg
Near Infrared Spectroscopy in Patients Undergoing Robotic Assisted Laparoscopic Surgery in the Trendelenburg Position
Some robotic endoscopic surgeries require a steep Trendelenburg position and a carbon dioxide pneumoperitoneum. This minimally invasive approach has the advantages of less postoperative pain, shorter hospital stay and faster…
- Trial name
- NCT02829242
- Testing
- NIRS Monitoring (SenSmart Monitor)
- Where
- Austria
- Volunteers
- 16 people
- Sponsor
- Medical University of Vienna
Abdominal Compartment Syndrome
This Study Performed to Develop a New Technique for Measuring the Intra Abdominal Pressure
The purpose of this study is to evaluate the changes of intraocular pressure due to the increase of intra abdominal pressure.
- Trial name
- NCT02319213
- Testing
- Intraocular pressure measurement with 9 mmHg insufflation, Intraocular pressure measurement with 12 mmHg insufflation, Intraocular pressure measurement with 15 mmHg insufflation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Obesity, Intra-Abdominal Hypertension
Chest Wall Influence on Respiratory System Mechanics in Morbidly Obese Patients
The goal of this study is to describe the influence of the chest wall on the respiratory system mechanics in morbidly obese patients and in patients with high intra-abdominal pressure.
- Trial name
- NCT02105220
- Testing
- Respiratory mechanics assessment
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Massachusetts General Hospital
Compartment Syndrome Traumatic Lower Extremity, Compartment Syndrome Traumatic Upper Extremity
Clinical Trial of a New Device for Real-Time Muscle Pressure Measurements in Patients at Risk for Acute Compartment Syndrome
Compartment syndrome remains a very serious complication of lower extremity trauma and/or procedural cases that involved lower or upper extremity surgery.
- Trial name
- NCT04012723
- Testing
- MY01 Continuous Compartmental Pressure Monitor
- Where
- 5 sites in Canada
- Volunteers
- 100 people
- Sponsor
- MY01 Inc.
Compartment Syndrome Nontraumatic Lower Extremity
The Effects of Prolonged Head-Down Tilt Lithotomy Position on Lower Limb Haemodynamics
During certain bowel surgeries for cancer (colorectal surgery), individuals frequently have to be placed in a head-down position to enable surgeons have optimal access to the cancer site.
- Trial name
- HELP (NCT06036641)
- Testing
- NIRS monitoring, Laser Doppler flowmetry, Inflammatory and Oxidative stress biomarkers
- Where
- United Kingdom
- Volunteers
- 26 people
- Sponsor
- University of Portsmouth
Compartment Syndrome of Leg, Healthy
Detecting Compartment Syndrome Pain in the Presence of Regional Anesthesia in Healthy Volunteers
The goal of the study is to determine how different types of Regional Anesthesia (nerve blocks) can be helpful to patients with lower extremity trauma who develop compartment syndrome (an increased pressure in the fascial…
- Trial name
- NCT04113954
- Testing
- Mepivacaine Injection
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital