Clinical trials: Compartment Syndromes
Intraabdominal Hypertension, Breast Neoplasms
DIEP Flap Surgery and Intraabdominal Pressure
Aim: The primary aim of this study is to test if closure of the abdominal donor site increases the Intraabdominal Pressure (IAP) in women undergoing secondary Deep Inferior epigastric perforator (DIEP) flap breast reconstruction.
- Trial name
- NCT05764577
- Testing
- DIEP flap surgery
- Where
- Denmark
- Volunteers
- 13 people
- Sponsor
- Aalborg University Hospital
Critically Ill, Intra-Abdominal Hypertension
The Influence of Fluid Removal Using Continuous Venovenous Hemofiltration (CVVH) on Intra-abdominal Pressure and Kidney Function
Intra- abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) are a cause of organ dysfunction in critically ill patients.
- Conditions
- Critically Ill, Intra-Abdominal Hypertension, Abdominal Compartment Syndrome, Acute Kidney Injury
- Trial name
- NCT01077895
- Testing
- CVVH, ultrafiltration, ultrafiltration control group
- Where
- 2 sites in Belgium
- Sponsor
- University Hospital, Ghent
Severe Acute Pancreatitis, Intra-abdominal Hypertension
Efficacy and Safety of Da-Cheng-Qi Decoction in Severe Acute Pancreatitis
This single-center prospective randomized controlled trial evaluated Da-Cheng-Qi Decoction (DCQD) as the acute-stage intervention of an integrated traditional Chinese and Western medicine whole-stage treatment protocol for severe…
- Trial name
- NCT07816900
- Testing
- Da-Cheng-Qi Decoction Plus Standard Western Treatment, Standard Western Treatment
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Critical Illness, Acute Kidney Injury
Collective Accuryn Physiologic Signals and Signatures
The CAPSS Study is a retrospective and prospective, multi-center, single-arm post-market data collection study with an FDA cleared device.
- Conditions
- Critical Illness, Acute Kidney Injury, Sepsis, Septic Shock
- Trial name
- CAPSS (NCT03817281)
- Testing
- Accuryn Monitoring System
- Where
- United States
- Sponsor
- Potrero Medical
Acute Respiratory Distress Syndrome, Acute Kidney Injury
Prone Position and Renal Resistive Index
Patients suffering from Acute Respiratory Distress Syndrome (ARDS) with a prone position (PP) indication will benefit from measurements of renal resistive index, intra-abdominal pressure (IAP), urinary oxygen tension (uPO2) and…
- Conditions
- Acute Respiratory Distress Syndrome, Acute Kidney Injury, Prone Position, Intra-Abdominal Hypertension
- Trial name
- PRO-KIDNEY (NCT04286490)
- Testing
- Prone position
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Grenoble
HIV Infections
Body Compartment PK for New HIV Pre-exposure Prophylaxis Modalities
The purpose of this study is to determine the ability of new anti-HIV agents to penetrate different body compartments in HIV negative men who have sex with men and transgender women.
- Trial name
- NCT02985996
- Testing
- Truvada, Genvoya
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Emory University
Hernia Abdominal Wall, Botox Injection
Preoperative BOTOX® Injection for Large Ventral Hernia Repair
This study is for adults who need open surgery to repair a very large abdominal (ventral) hernia. This study tests whether a one-time, image-guided injection of a medicine commonly known as "BOTOX®" (onabotulinumtoxinA) into the…
- Conditions
- Hernia Abdominal Wall, Botox Injection, Hernia Incisional Ventral, Hernia Repair With Compartment Syndrome
- Trial name
- PRETOX (NCT07220382)
- Testing
- OnabotulinumtoxinA Injection, OnabotulinumtoxinA, 0.9 % Normal Saline
- Where
- United States
- Volunteers
- 188 people
- Sponsor
- The Cleveland Clinic
Compartment Syndromes
Long Term Outcomes of Pediatric Compartment Syndrome
The goal of this study is to review the etiology, diagnostic criteria, complications and outcome of acute pediatric compartment syndrome identified at The Children's Hospital of Western Ontario (CHWO) .
- Trial name
- NCT03540394
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Hernia Repair With Compartment Syndrome
Feasibility Study of The Use of FLEX HD® Surgical Implant or STRATTICE® Reconstructive Tissue Matrix in The Closure of Abdominal Wall Defects With Component Separation in Clean or Contaminated Cases
This study examines the feasibility of using Flex HD® Surgical Implant or STRATTICE® Reconstructive Tissue Matrixin the repair of hernias.
- Trial name
- Flex HD (NCT01597128)
- Testing
- Flex HD, Strattice
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- John Roth
Limb Ischemia, Compartment Syndrome of Leg
Chemical Analysis of Limb Microfluidics
Compartment syndrome (CS) is a condition where an increase in pressure in an anatomical compartment (e.g. the lower leg) affects the blood supply of the tissues, leading to tissue damage.
- Trial name
- CALM (NCT06050499)
- Testing
- Microdialysis catheter + biosensor
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- Imperial College London
Delirium, Intraabdominal Hypertension
Effect of the Intra-abdominal Pressure on the Risk of Delirium in Mechanically Ventilated Patients.
intra-abdominal hypertension (IAH) and delirium are serious, high-frequency complications in intensive care unit (ICU) patients.
- Conditions
- Delirium, Intraabdominal Hypertension, Mechanical Ventilation Complication
- Trial name
- NCT03218358
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Intra-Abdominal Hypertension, Critical Illness
Intra-Abdominal Pressure Changes During Continuous Renal Replacement Therapy in Critically Ill Patients
This prospective observational study will evaluate changes in intra-abdominal pressure in critically ill adult patients receiving continuous renal replacement therapy in the intensive care unit.
- Conditions
- Intra-Abdominal Hypertension, Critical Illness, Continuous Renal Replacement Therapy
- Trial name
- NCT07823387
- Testing
- Intravesical Intra-abdominal Pressure Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 95 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Compartment Syndrome of Forearm
Clinical Application and Validation of Innovative Tourniquet
Background: Tourniquets are the basic equipment for nurses to perform blood draws, and venous indwelling needles for congestion, or for hemostasis.
- Trial name
- NCT05605990
- Testing
- Innovative tourniquet (Acusense Nonpneumatic tourniquet)
- Where
- Taiwan
- Volunteers
- 160 people
- Sponsor
- National Cheng-Kung University Hospital
Intra-Abdominal Hypertension, Abdominal Compartment Syndrome
Abdominal Compartment Syndrome : Diagnostic and Prognostic Value of CT Findings - a Prospective Study
Abdominal Compartment Syndrome (ACS) is a well known condition occuring in critically ill patients in intensive care units. This syndrome features a sustained intra abdominal hypertension (IAH) above 20 mmHg and a multiple organ…
- Trial name
- SCANAPIV (NCT02814734)
- Volunteers
- 140 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Chronic Exertional Compartment Syndrome
Botulinum for Chronic Exertional Compartment Syndrome
We will investigate the feasibility of a simple outpatient one time injection regimen for the treatment of Chronic Exertional Compartment Syndrome (CECS).
- Trial name
- Botox (NCT03339921)
- Testing
- Botulinum toxin injections for chronic compartment syndrome, surgical fasciotomy for chronic compartment syndrome
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- 375th Medical Group, Scott Air Force Base
Compartment Syndrome
Double Blinded, Randomized Clinical Trial of the Twin Star ECSPRESS Monitoring System for the Reduction of the Incidence of Fasciotomy
The proposed study is a double-blinded, randomized clinical trial of tissue pressure monitoring only (Control group) vs. tissue pressure monitoring plus tissue ultrafiltration (Treatment group) in patients with tibia fractures…
- Trial name
- ECSPRESS (NCT01879696)
- Testing
- ECSPRESS catheter with active vacuum
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Twin Star Medical, Inc.
Intraabdominal Hypertension, Abdominal Compartment Syndrome
Comparison of Bladder Pressure Versus Regional Intestinal Tissue Oxygenation in Infants
The goal of this clinical trial is to learn more about intestinal regional oxygen saturation measurements made with near-infrared spectroscopy and bladder pressure measurements in infants without risk of intraabdominal…
- Trial name
- BPvsNIRS (NCT05971264)
- Testing
- Near infrared-spectroscopy
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital, Zurich
Intraabdominal Hypertension, Multi-Organ Disorder
Correlation Between Intra-abdominal Pressure, Biomarkers of Bacterial Translocation and Intestinal Wall Damage
Main scientific hypotheses of the project: 1. The level of intestinal microflora translocation markers and biomarkers of intestinal wall damage the in the blood serum correlates with the level of intra-abdominal pressure…
- Conditions
- Intraabdominal Hypertension, Multi-Organ Disorder, Translocation Syndrome
- Trial name
- NCT06221293
- Testing
- immunoenzyme analysis
- Where
- 5 sites in Kazakhstan
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Karaganda Medical University
Muscle Oxygenation, Skin Pigmentation
Muscle Oxygenation and Skin Pigmentation
The investigators plan to enroll 500 consecutive Subjects at a major trauma center for this study. For each patient, the body mass index (BMI), age, sex, diastolic pressure and mean arterial pressure (MAP) at time of…
- Trial name
- NCT00747162
- Testing
- Measure of muscle oxygenation, Skin pigmentation determination
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Emory University
Morbid Obesity, Intra-Abdominal Hypertension
Correlation of Intra-abdominal Pressure With Gastric and Urinary Bladder Pressures in Patients With Morbid Obesity
The correlations between gastric and urinary bladder pressures with Intra-abdominal pewssure have not been addressed
- Conditions
- Morbid Obesity, Intra-Abdominal Hypertension, Bariatric Surgery Candidate
- Trial name
- NCT04481880
- Testing
- measuring IAP and respiratory parameters
- Volunteers
- 12 people
- Sponsor
- Rambam Health Care Campus