Clinical trials: Compartment Syndromes
Compartment Syndromes
Percutaneous Catheter Decompression in the Treatment of Elevated Intra-abdominal Pressure
Intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) have traditionally been treated surgically through emergent laparotomy.
- Trial name
- NCT01230255
- Testing
- Percutaneous catheter drainage
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Orlando Regional Medical Center
Damage Control, Trauma Abdomen
BIA Guided-fluid Management in Postinjury Open Abdomen
Fluid overload (FO), resulting from high volume fluid therapy, is frequent and contributes to excessive visceral edema, delayed fascial closure, and adverse outcomes among postinjury open abdomen (OA) patients.
- Conditions
- Damage Control, Trauma Abdomen, Acute Compartment Syndrome
- Trial name
- BGFM (NCT03466684)
- Testing
- BIA-guided fluid resuscitation protocol, Traditional fluid resuscitation protocol
- Volunteers
- 140 people
- Sponsor
- Nanjing PLA General Hospital
CEC Syndrome
Non-invasive Measurement of Compartment Pressure: Reliability
The investigators want to investigate the reliability (variability) of a new device, that should be able to measure lower leg compartment pressure non-invasively. Therefore the tool is used under different circumstances.
- Trial name
- NCT05720182
- Testing
- Compremium Compressibility Measurement, Treadmill Running, Questionnaire
- Where
- Netherlands
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Kay van Heeswijk
Human Volunteers
In Vivo Optical Spectroscopy Monitoring in a New Model of Muscular Compartment Syndrome
Muscular compartment syndrome (MCS) is consecutive to an increase in intramuscular compartment pressures, and is a rare but serious postoperative complication.
- Trial name
- NCT01452425
- Testing
- Tourniquet, INVOS assessment, EMG assessment
- Where
- Belgium
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Université Catholique de Louvain
Acute Compartment Syndrome
Ability of Near Infrared Spectroscopy to Isolate Compartments of the Extremity
Near infrared spectroscopy (NIRS) provides a non-invasive means of continuously monitoring tissue oxygenation, which may be useful for diagnosis of acute compartment syndrome (ACS).
- Trial name
- NCT01283451
- Testing
- Muscle contraction
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- J&M Shuler
Intra-Abdominal Hypertension, Abdominal Compartment Syndrome
Intra-abdominal Hypertension in Critically Ill Patients
The aim of the proposed study is to determine the incidence and prevalence of intra-abdominal hypertension and abdominal compartment syndrome in consecutive intensive care admissions using broad inclusion criteria.
- Trial name
- NCT02514135
- Testing
- No intervention
- Where
- Canada
- Volunteers
- 286 people
- Sponsor
- Western University, Canada
Limb Ischemia, Compartment Syndrome of Leg
Chemical Analysis of Limb Microfluidics
Compartment syndrome (CS) is a condition where an increase in pressure in an anatomical compartment (e.g. the lower leg) affects the blood supply of the tissues, leading to tissue damage.
- Trial name
- CALM (NCT06050499)
- Testing
- Microdialysis catheter + biosensor
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- Imperial College London
Compartment Syndrome
Study of New Catheter & Pressure Monitor System to Help Prevent Compartment Syndrome From Developing in the Injured Leg
An investigation of a new catheter and pressure monitor system that may help to prevent a complication called compartment syndrome from developing in an injured leg.
- Trial name
- TS2 (NCT00681616)
- Testing
- Compartment Monitoring System (CMS), Compartment Monitoring System with Active Fluid Removal, Compartment Monitoring System without fluid removal
- Where
- 13 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Twin Star Medical, Inc.
Traumatic Brain Injuries, Intracranial Hypertension
Security and Effectiveness Assessment of Locking Systems in Ventriculostomy for Traumatic Brain Injury
This study aims to compare the effectiveness and safety of a standard intervention called ventriculostomy for managing increased intracranial pressure (ICP) in patients with severe traumatic brain injury (TBI).
- Trial name
- SEALS-TBI (NCT06772155)
- Testing
- Ventriculostomy, Ventriculostomy + Locking Device
- Volunteers
- 292 people
- Sponsor
- Meditech Foundation
Intra-Abdominal Hypertension
The Influence of Furosemide on Fluid Balance and Intra-abdominal Pressure in Critically Ill Patients
Intra-abdominal hypertension (IAH) is a frequent cause of organ dysfunction in critically ill patients. Secondary IAH is mainly caused by excessive fluid resuscitation.The World Society for the Abdominal Compartment Syndrome…
- Trial name
- NCT01072071
- Testing
- furosemide
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Ziekenhuis Netwerk Antwerpen (ZNA)
Intra-Abdominal Hypertension
Intra-abdominal Hypertension and Associated Factors Among Patients Admitted in Intensive Care Units in Uganda.
The study was carried out to determine the prevalence,incidence and factors associated with intra-abdominal hypertension among patients admitted in three intensive care units in Kampala Uganda.
- Trial name
- NCT03567265
- Where
- Uganda
- Volunteers
- 126 people
- Sponsor
- Makerere University
Intra-Abdominal Hypertension, Respiratory Mechanics
Intra-Abdominal Pressure, Respiratory Mechanics, and Ventilator Liberation After Emergency Major Laparotomy
This prospective observational cohort study aims to investigate the relationship between intra-abdominal pressure (IAP), respiratory system mechanics, and successful liberation from invasive mechanical ventilation in adult…
- Conditions
- Intra-Abdominal Hypertension, Respiratory Mechanics, Mechanical Ventilation
- Trial name
- IAP-VENT (NCT07889609)
- Testing
- Serial Intra-Abdominal Pressure and Respiratory Mechanics Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Critical Illness, Intra-Abdominal Hypertension
Intraabdominal Pressure in Critically Ill Patients
This study is conducted to evaluate the incidence and prognostic significance of IAH in medical ICU patients.
- Trial name
- NCT03670771
- Testing
- Harrahill method for measuring of intraabdominal pressure
- Volunteers
- 100 people
- Sponsor
- Assiut University
Compartment Syndrome of Leg, Healthy
Detecting Compartment Syndrome Pain in the Presence of Regional Anesthesia in Healthy Volunteers
The goal of the study is to determine how different types of Regional Anesthesia (nerve blocks) can be helpful to patients with lower extremity trauma who develop compartment syndrome (an increased pressure in the fascial…
- Trial name
- NCT04113954
- Testing
- Mepivacaine Injection
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Anterior Knee Pain Syndrome
In Vivo Arthroscopic Behavior of the Infrapatellar Plica of the Knee
Anterior knee pain has been an enigmatic problem for orthopedic surgeons. Recent studies, as well as the clinical observation of the principle investigator have suggested that arthroscopic resection of the infrapatellar plica…
- Trial name
- NCT00643487
- Testing
- observation of the behavior of the infrapatellar plica
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- State University of New York - Upstate Medical University
Chronic Exertional Compartment Syndrome
Utilization of High Frequency Ultrasound to Diagnose Chronic Exertional Compartment Syndrome
The purpose of this study is to investigate high frequency ultrasound as a future modality for the diagnosis of chronic exertional compartment syndrome (CECS).
- Trial name
- NCT03736174
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Colorado, Denver
Intra-Abdominal Hypertension
Intra-abdominal Pressure (IAP) During PFA Treatment of A-fib/ A-Flutter
The purpose of this study is to investigate the intra-abdominal pressure utilizing the Accuryn monitoring system during pulsed field ablation procedures in the electrophysiology lab compared to the type of anesthetic utilized.
- Trial name
- IAP (NCT06876896)
- Testing
- Accuryn Foley catheter device
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Wake Forest University Health Sciences
Acute Compartment Syndrome
Real-Time Muscle Pressure Measurements in Patients at Risk for Acute Compartment Syndrome
The purpose of this trial is to conduct a pilot study that will aid in the design of an evaluation of the clinical benefit of MY01, an FDA cleared device, that allows continuous monitoring of intracompartmental muscle pressure in…
- Trial name
- NCT04671173
- Testing
- Measurement of the Intra-Compartmental Pressure with the MY01 device
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Compartment Syndrome Traumatic Lower Extremity
BM-MNCs for Lower Extremity Compartment Syndrome Injury
This is a phase 1 study to assess safety and tolerability of intramuscular administration of two different doses of autologous bone marrow mononuclear cells (BM-MNCs) for treatment of lower extremity injury complicated by…
- Trial name
- NCT03880656
- Testing
- Intramuscular administration of autologous BM-MNCs
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Oregon Health and Science University
Acute Compartment Syndrome
The Use of Near Infrared Spectroscopy in the Diagnosis of Acute Compartment Syndrome in Injured Soldiers
The purpose of this study is to define the reliability and accuracy of Near Infrared Spectroscopy (NIRS) in the detection of intra-compartmental tissue perfusion in injured and noninjured extremities over time.
- Trial name
- NCT01123798
- Testing
- near-infrared spectroscopy
- Where
- Germany
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- J&M Shuler