Clinical trials: Complex Care
Pregnancy, Periodontal Disease
Lactoferrin-Based Oral Care for Periodontal Health in Pregnancy
This randomized controlled clinical trial aims to evaluate the effectiveness of a lactoferrin-based oral hygiene protocol in improving periodontal health during pregnancy.
- Conditions
- Pregnancy, Periodontal Disease, Gingivitis, Oral Microbiota
- Trial name
- LBC-PREG (NCT07069140)
- Testing
- Lactoferrin-based Toothpaste and Mouthwash (Emoform Glic), Lactoferrin-Based Toothpaste Only (Emoform Glic)
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Pavia
Biliary Stones
Non-Complex Biliary Stones DSC vs ERC
To prospectively compare non-complex biliary stone clearance using fluoroscopy/radiation-free direct solitary cholangioscopy (DSC) utilizing the SpyGlass™ system with non-complex biliary stone clearance using standard endoscopic…
- Trial name
- NCT03421340
- Testing
- DSC, ERC
- Where
- 8 sites in United States, India and 2 more
- Volunteers
- 250 people
- Sponsor
- Boston Scientific Corporation
Complex Patient, Multimorbidity
Pursuing the Triple Aim in Hotspotters: Identification and Integrated Care
Hotspotters are patients with complex care needs, defined by problems in multiple life domains and high acute care use. These patients often receive mismatched care, resulting in overuse of care and increased healthcare costs.
- Conditions
- Complex Patient, Multimorbidity, Psychosocial Problem, Chronic Disease
- Trial name
- NCT05878054
- Testing
- Proactive, integrated and personalised care
- Where
- Netherlands
- Volunteers
- 41 people
- Sponsor
- Leiden University Medical Center
Complex Care, Post-Acute Care Utilization
Comprehensive Enhanced Care Management Under CalAIM for High-Risk Medi-Cal Members
This pragmatic, cluster-randomized trial will evaluate whether a comprehensive CalAIM-aligned care model consisting of Enhanced Care Management, selected Community Supports, Transitional Care Services, and residential care…
- Conditions
- Complex Care, Post-Acute Care Utilization, Housing Instability, Residential Care Transition
- Trial name
- COMPASS-CalAIM (NCT07587073)
- Testing
- Comprehensive CalAIM Care Bundle, Usual CalAIM Service Delivery
- Where
- United States
- Volunteers
- 1,200 people
- Sponsor
- StratiHealth
Aging, Functional Recovery
Supplemental Mobility
This pilot study will evaluate the feasibility of a supplemental mobility intervention, the Safe Transfers And Mobility Program (STAMP).
- Conditions
- Aging, Functional Recovery, Skilled Nursing Facility, Medically Complex
- Trial name
- NCT07872384
- Testing
- High Intensity Rehabilitation, Safe Transfers and Mobility Program, Usual Care
- Where
- 2 sites in United States
- Volunteers
- 192 people
- Sponsor
- University of Colorado, Denver
Antimicrobial Drug Resistance
A Complex Intervention to Promote Appropriate Antibiotic Use Among Rural Residents Based on the Metaphor-Embedded Integrated Behavioral Model
The study aims to address the question of how to provide effective health education on health topics with high medical specialisation (e.g.
- Trial name
- NCT06967766
- Testing
- health education based on the Metaphor-Embedded Integrated Behavioral Model
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Bo Yan
Primary Health Care, Quality of Health Care
Aligning Patients and Their Primary Care Providers
This project focuses on improving the patient-provider primary care visit interaction by addressing the need to align patient and provider priorities in a way that incorporates patients' goals and preferences while supporting the…
- Conditions
- Primary Health Care, Quality of Health Care, Comorbidity, Communication
- Trial name
- APP (NCT02707146)
- Testing
- Visit Planner, Attention Control Pamphlet, iPad
- Where
- United States
- Volunteers
- 750 people
- Sponsor
- Kaiser Permanente
Hypertension
Complex Exercise Intervention to Normalize Blood Pressure and Nocturnal Dipping in Patients With Hypertension
Background: Non-dipping hypertension(HT) (as defined by lack of decrease in systolic blood pressure (BP) by 10% during sleep) predicts cardiovascular events and mortality; however, there is a lack of evidence based treatment for…
- Trial name
- END-HT (NCT03923907)
- Testing
- EIM intervention group
- Where
- Hong Kong
- Volunteers
- 198 people
- Sponsor
- Chinese University of Hong Kong
Breast Cancer, Colorectal Cancer
Care Coordination for Complex Cancer Survivors in an Integrated Safety Net System
Nearly 70% of people living with cancer are "complex patients" with multiple chronic conditions who must deal not only with effects of their cancer but also continuing diseases such as diabetes, depression, hypertension, or heart…
- Trial name
- NCT02943265
- Testing
- Care Coordination Strategies
- Where
- United States
- Volunteers
- 4,322 people
- Sponsor
- University of Texas Southwestern Medical Center
Children With Medical Complexity
Complex Care for Kids Ontario (CCKO)
There are ~6,200 children in Ontario with special and complex healthcare needs requiring multiple services from many different doctors and other healthcare providers.
- Trial name
- NCT02928757
- Testing
- Complex care clinic as part of the CCKO initiative
- Where
- 4 sites in Canada
- Volunteers
- 160 people
- Sponsor
- The Hospital for Sick Children
Asthma, Coronary Artery Disease
Care Transitions for Complex Patient - Cycle 1 and Cycle 2
The purpose of this study is to improve patient care and safety while decreasing ED visit rates by sending specific information about care transitions related to hospital admission and discharge and emergency department and…
- Conditions
- Asthma, Coronary Artery Disease, Diabetes, Hypertension
- Trial name
- NCT01039324
- Testing
- Reports, Reports and Notices, Usual care
- Where
- United States
- Volunteers
- 8,422 people
- Sponsor
- Duke University
Medical Complexity
ASKids! Inpatient Agenda-Setting Study for Hospitalized Children With Medical Complexity
The goal of this open pilot is to co-design and test a clinical agenda-setting intervention in the inpatient pediatric environment.
- Trial name
- ASKids (NCT07127666)
- Testing
- Structured Agenda-Setting Tool
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Stroke
Managing Aftercare for Stroke (MAS): MAS-II - A Longitudinal Complex-interventional Study in Post-rehabilitation Stroke Patients
After discharge from hospital, the current healthcare system in Germany allows considerable flexibility (therefore complexity) of patient access and mobility between multiple care providers in the community setting.
- Trial name
- NCT03097146
- Testing
- comprehensive multidisciplinary stroke care
- Where
- Germany
- Volunteers
- 61 people
- Sponsor
- Charite University, Berlin, Germany
Fall, Pressure Ulcer
PROSENIOR. Prevention of Pressure Ulcers, Malnutrition, Poor Oral Health and Falls Among Older Persons Receiving Municipal Health Care and Are Registered in the Quality Registry Senior Alert
Inclusion criteria for study I and II is nurse aides, registered nurses and managers working in nursing homes who register in Senior Alert.
- Conditions
- Fall, Pressure Ulcer, Malnutrition, Oral Health
- Trial name
- NCT05308862
- Testing
- Care process for assessements of risks
- Where
- Sweden
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Malmö University
Relatives, Health Care Providers
A Complex Intervention Study on a Palliative Rehabilitation Blended Learning Program to Support Relatives and Health Care Providers of People With ALS and Cognitive Impairments in Coping With Challenges
A complex intervention study on a palliative rehabilitation blended learning program to support relatives and health care providers of people with ALS and cognitive impairments in coping with challenges.
- Conditions
- Relatives, Health Care Providers, Cognitive Impairment, Rehabilitation
- Trial name
- NCT04638608
- Testing
- EMBRACE (relatives), EMBRACE (Health care providers)
- Where
- Denmark
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Danish Rehabilitation Centre for Neuromuscular Diseases
Depression
Cluster Randomized Trial of Stepped Care Intervention vs. Treatment as Usual for Patients With Depression
The main aim of the project is the implementation and evaluation of a stepped care model (SCM) for patients with depression with 6 treatment options of varying intensity and setting, including innovative technologies (e-mental…
- Trial name
- SCM (NCT01731717)
- Testing
- Active monitoring, Bibliotherapy, Online self-help
- Where
- Germany
- Volunteers
- 737 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf