Clinical trials: Complex Coronary Artery Disease
Cardiogenic Shock, PCI Patients
Clinical Outcomes of Contemporary IMPELLA Devices in Cardiogenic Shock and High-risk Percutaneous Coronary Intervention
The IMMERGE registry is an observational, international multicentric study, including patients underwent IMPELLA implantation in the participating centers both for cardiogenic shock and high-risk PCI.
- Conditions
- Cardiogenic Shock, PCI Patients, Mechanical Circulatory Support
- Trial name
- IMMERGE (NCT06690567)
- Testing
- Impella implantation
- Where
- Italy
- Volunteers
- 700 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Coronary Heart Disease, Coagulation Disorder
Anfibatide Phase 1 Clinical Trial in Healthy Volunteers
In this 94 healthy subjects Phase I clinical trial, we assess the clinical profile of Anfibatide, a specific glycoprotein Ib antagonist.
- Trial name
- NCT01588132
- Testing
- Anfibatide
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Lee's Pharmaceutical Limited
Coronary Artery Disease, Percutaneous Coronary Intervention
Xience Registry In Complex Lesion of Acute Coronary Syndrome Patients witH Ticagrelor (RICH)
The goal of this multicenter prospective clinical cohort study is to investigate the impact of early use of low-dose Ticagrelor-based dual antiplatelet agent therapy (TDAPT) (ticagrelor 120mg daily; l-TDAPT) as compared to…
- Conditions
- Coronary Artery Disease, Percutaneous Coronary Intervention, Acute Coronary Syndrome
- Trial name
- RICH (NCT05746416)
- Where
- South Korea
- Volunteers
- 977 people
- Sponsor
- Hanyang University Seoul Hospital
HIV Infections, Coronary Disease
HIV-HEART Aging Study
The HIV/HEART Aging study (HIVH) is an ongoing, prospective, multicentre trial that was conducted to assess the incidence, the prevalence and the clinical course of cardiovascular diseases (CVD) in HIV-infected patients.
- Conditions
- HIV Infections, Coronary Disease, Myocardial Infarction, HIV Encephalopathy
- Trial name
- HIVH (NCT04330287)
- Where
- 5 sites in Germany
- Volunteers
- 2,000 people
- Sponsor
- University Hospital, Essen
Coronary Artery Disease, Heart Failure
PIONEER Trial:Hemodynamic Support With ECMO and IABP in Elective Complex High-risk PCI
To determine whether hemodynamic support combining VA-ECMO with IABP could mitigate the rates of Major Adverse Cardiovascular and Cerebrovascular Events (MACCEs), compared with IABP support alone, in patients undergoing elective…
- Trial name
- NCT04045873
- Testing
- extracorporeal membrane oxygenation
- Volunteers
- 306 people
- Sponsor
- Xijing Hospital
High-risk PCI, Coronary Artery Disease Risk High
Use of Mechanical Left ventricuLar Unloading in Complex Higher-risk Indicated Procedures
If there is a narrowing or blockage in the coronary arteries of the heart, the cardiologist may choose to treat this blockage. This is called percutaneous coronary intervention (PCI), which involves both balloon angioplasty and…
- Trial name
- UNLOAD-CHIP (NCT07380217)
- Testing
- Mechanical circulatory support with the Pulsecath iVAC2L device
- Where
- 8 sites in Netherlands
- Volunteers
- 98 people
- Sponsor
- Amsterdam UMC, location VUmc
Coronary Artery Disease
Study Examining the PROMUS Element Everolimus-eluting Stent in Multi-center Coronary Intervention of Complex Arterial Lesion Subsets
Randomized trials have demonstrated an excellent safety and efficacy profile for the chromium everolimus-eluting stent. The platinum chromium everolimus-eluting sten (PtCr-EES) uses the identical antiproliferative agent and…
- Trial name
- SPECIALIST (NCT01670318)
- Testing
- platinum chromium everolimus-eluting stent (PROMUS Element by Boston Scientific, Massachusetts)
- Where
- 38 sites in Japan
- Volunteers
- 800 people
- Sponsor
- The PCI Guideline Research Society