Clinical trials: Complex Posttraumatic Stress Disorder
Chronic Insomnia, Sleep Deprivation
Evaluating the Efficacy and Safety of PROSOMNIA Sleep Therapy™ in Patients With Sleep Deprivation and Chronic Insomnia
This clinical trial aims to evaluate the safety and efficacy of PROSOMNIA Sleep Therapy (PSTx) for individuals suffering from chronic insomnia, sleep deprivation, and REM sleep disorders.
- Conditions
- Chronic Insomnia, Sleep Deprivation, REM Behavior Disorder, REM Sleep Behavior Disorder
- Trial name
- PSHW (NCT06644573)
- Testing
- PROSOMNIA Sleep Therapy™ (PSTx), Anesthesia-Induced Sleep Therapy, Diprivan (propofol), Astra-Zeneca
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nyree Penn
Complex Post-Traumatic Stress Disorder (CPTSD), Borderline Personality Disorder (BPD)
Study of Emotional Dysregulation in Complex Post-Traumatic Stress Disorder
This study aims to characterize emotional dysregulation in complex post-traumatic stress disorder (cPTSD) and to determine the extent to which it can promote the distinction with borderline personality disorder (BPD) and…
- Conditions
- Complex Post-Traumatic Stress Disorder (CPTSD), Borderline Personality Disorder (BPD), Post-traumatic Stress Disorder (PTSD)
- Trial name
- TR-EMA (NCT06848127)
- Testing
- Self-questionnaires, Cognitive assessment, Momentary Ecological Assessment (EMA)
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Safety, Psychological, Acceptability of Health Care
Body-oriented Psychotherapy for Individuals With a History of Child Maltreatment and Trauma-related Symptoms
This Pilot Randomized Controlled Trial (RCT) overall aim is to establish the safety, feasibility, acceptability and preliminary effects of a body-oriented psychotherapy, Somatic Experiencing (SE), on social functioning and mental…
- Conditions
- Safety, Psychological, Acceptability of Health Care, Psychological Safety, Maltreatment, Child
- Trial name
- NCT06549777
- Testing
- SE-group, Control
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Monique Pfaltz
Bipolar Disorder, Posttraumatic Stress Disorder
Study to Promote Innovation in Rural Integrated Telepsychiatry
Background: Community Health Centers care for over 20 million rural, low income and minority Americans every year. Patients often have complex mental health problems such as Posttraumatic Stress Disorder (PTSD) and Bipolar…
- Trial name
- SPIRIT (NCT02738944)
- Testing
- Telepsychiatry Collaborative Care, Telepsychiatry Enhanced Referral
- Where
- 13 sites in United States
- Volunteers
- 1,004 people
- Sponsor
- University of Washington
Complex Post-Traumatic Stress Disorder
Patient-centered Modular CBT for CPTSD: A Randomised Controlled Pilot Study
Modular Patient Centred CBT (MPC) for Complex PTSD (CPTSD) is a manualized psychotherapy programme that consists of five treatment modules addressing 1) Affect dysregulation, 2) Disturbed relationships, 3) Negative self-concept…
- Trial name
- PACE pilot RCT (NCT05259592)
- Testing
- Psychotherapy
- Where
- 5 sites in Denmark
- Volunteers
- 60 people
- Sponsor
- Danish Veterans Centre
Borderline Personality Disorder (BPD), PTSD - Post Traumatic Stress Disorder
Pilot Study for the Evaluation of a New Psychotherapeutic Treatment for Borderline Personality Disorder Patients With Post-traumatic Stress Symptoms
Borderline Personality Disorder (BPD) is a serious mental health condition that often co-occurs with Complex PTSD (CPTSD), making treatment more challenging.
- Trial name
- MBT-TF (NCT07305155)
- Testing
- Standard Mentalization-Based Treatment, Trauma-Focused Mentalization-Based Treatment
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Eva Rüfenacht
Complex Post-Traumatic Stress Disorder
A Pilot Study of a Trauma-Sensitive Mindfulness and Compassion Intervention
This mixed-methods pilot study aim to assess the changes in symptoms of post-traumatic stress disorder (PTSD), complex post-traumatic stress disorder (CPTSD), dissociative symptoms, self-critique, and self-compassion following…
- Trial name
- NCT05993468
- Testing
- TMC Treatment Approach
- Where
- Norway
- Volunteers
- 17 people
- Sponsor
- Modum Bad
Trauma, Mental Health Disorder
Investigating the Effect of Evidence-based Treatment for Post-traumatic Stress Disorder Among Youth
Trauma-focused cognitive-behavioral therapy (TF-CBT) is an evidence-based practice (EBP) for the treatment of posttraumatic stress disorder (PTSD) and posttraumatic stress symptoms (PTSS) among children and adolescents.
- Conditions
- Trauma, Mental Health Disorder, PTSD, Implementation
- Trial name
- NCT05226481
- Testing
- Trauma-focused cognitive behavioral therapy (TF-CBT)
- Where
- Norway
- Volunteers
- 216 people
- Sponsor
- Norwegian Center for Violence and Traumatic Stress Studies
Post Traumatic Stress Disorder
Identification of the Clinical Specificities of Complex Posttraumatic Stress Disorder
Identification of the clinical specificities of complex post-traumatic stress disorder post-traumatic stress disorder
- Trial name
- IDPLEX (NCT05592652)
- Testing
- Survey
- Where
- France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Anxiety Disorders, Complex Regional Pain Syndrome Type II
Regional Anesthesia Military Battlefield Pain Outcomes Study
The purpose of this study is to examine the short and long-term benefits of implementing early regional anesthesia techniques for pain control after a major traumatic injury to one or more extremities during combat in the…
- Conditions
- Anxiety Disorders, Complex Regional Pain Syndrome Type II, Depressive Disorders, Post-Traumatic Stress Disorder
- Trial name
- RAMBPOS (NCT00431847)
- Testing
- Regional Anesthesia, Standard Pain Management Protocol
- Where
- 3 sites in United States
- Volunteers
- 386 people
- Sponsor
- VA Office of Research and Development
Complex Post-Traumatic Stress Disorder
Survive & Thrive Trial With Male Offenders
Previous research has concluded that prison populations have particularly high rates of interpersonal trauma. There is however concern that these issues have been largely overlooked and misunderstood in the work undertaken with…
- Trial name
- NCT04887168
- Testing
- Survive & Thrive
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Edinburgh Napier University
Posttraumatic Stress Disorder
The Effectiveness of CFT for Reducing Self-criticism in Patients With Complex PTSD: a Single-case Experimental Study
PTSD is a mental disorder including psychological symptoms related to severe traumatic event(s). PTSD can negatively affect people's functioning in several life domains.
- Trial name
- NCT05791760
- Testing
- Compassion-focused therapy (CFT) for complex PTSD
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Twente
Post-Traumatic Stress Disorder
The Modum Bad Complex Posttraumatic Stress Disorder Study
This study compares three established, manual based psychotherapies for Complex Post-traumatic Stress disorder (CPTSD) in patients with childhood trauma (e.g. sexual abuse, violence).
- Trial name
- NCT03509844
- Testing
- Psychotherapy
- Where
- Norway
- Volunteers
- 96 people
- Sponsor
- Modum Bad
Complex Post-Traumatic Stress Disorder
Complex-Posttraumatic Stress Disorder - Cultural Adaptation of a Therapeutic Manual and Development of a Culture-specific Diagnostic Module for Refugee Populations in Switzerland (Pilot Trial)
In January 2022, the World Health Organization (WHO) launched the 11th edition of the International Classification of Diseases (ICD-11).
- Trial name
- NCT05917613
- Testing
- Enhanced Skills Training in Affective and Interpersonal Regulation combined with Modified Prolonged Exposure (ESTAIR/MPE)
- Where
- 2 sites in Switzerland
- Volunteers
- 24 people
- Sponsor
- Eva Heim
Psychiatric Health
Complex Post-traumatic Stress Disorder: What Symptomatological Specificities
A better understanding of the Complex Post-Traumatic Stress Disorder would allow a management as close as possible to the specificities of this one, but also a better training of professionals and adapted therapeutic indications.
- Trial name
- StuCoTra (NCT05070962)
- Testing
- clinical population
- Where
- France
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Raincy Montfermeil Hospital Group
Trauma
Identification of Post-Traumatic Stress Disorder in Adult Patients With Substance Use Disorders
The aim of this study is to show that early identification of PTSD and CPTSD would increase recognition of these disorders and facilitate diagnosis, referral and recovery.
- Trial name
- IRTIPAP (NCT06432400)
- Testing
- Patient questionnaires
- Where
- 2 sites in France
- Sponsor
- Hôpital NOVO
Posttraumatic Stress Disorder, Complex Post-Traumatic Stress Disorder
Using Data Science To Center Patient Perspectives in Mechanism Discovery
Including patient perspectives when developing new therapy interventions is crucial because it can help to understand response heterogeneity and promote engagement.
- Trial name
- CPP (NCT06233968)
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Cambridge Health Alliance
Post-traumatic Stress Disorder (PTSD), Emotional Contagion
Attachment and Post-Traumatic Stress Disorder in Military Personnel: Characterization of the French Military Population, Exploration of Biopsychosocial Factors, and Study of the Impact of Security Priming on Emotional Contagion Capacities
Post-traumatic stress disorder (PTSD) is a pathology that impairs the quality of life of sufferers. In military personnel, it can lead to military incapacity.
- Trial name
- AT-HOME (NCT06996275)
- Where
- France
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Complex Post-Traumatic Stress Disorder
RESTORE Trial: A Pilot RCT of Enhanced Skills Training in Affective and Interpersonal Regulation (ESTAIR) for Veterans With CPTSD
Complex Post traumatic Stress Disorder (CPTSD) is now recognized as a separate trauma-based psychological condition to PTSD. CPTSD is a broader diagnosis that includes the core PTSD symptoms (re-experiencing in the here and now…
- Trial name
- NCT04752072
- Testing
- Enhanced Skills Training in Affective and Interpersonal Regulation, Treatment as usual
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Combat Stress
Complex Post-Traumatic Stress Disorder
Eye Movement Desensitization and Reprocessing (EMDR) in Complex Psychotrauma
This study wants to demonstrate the effectiveness of combining a positive memory with "recommended" therapy based on EMDR in reducing the disturbance that patients with complex psychotrauma may experience.
- Trial name
- NCT04594434
- Testing
- Scale SUD, VOC scale, DES II scale
- Where
- France
- Volunteers
- 49 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche