Clinical trials: Complex Regional Pain Syndrome
Complex Regional Pain Syndrome
Study of TAK-935 as an Adjunctive Therapy in Adult Participants With Complex Regional Pain Syndrome (CRPS)
The purpose of this study is to investigate the effect of soticlestat (TAK-935) on calculated 24-hour average pain intensity by the numeric pain scale (NPS).
- Trial name
- NCT03990649
- Testing
- Soticlestat
- Where
- 3 sites in United Kingdom
- Volunteers
- 24 people
- Sponsor
- Millennium Pharmaceuticals, Inc.
Complex Regional Pain Syndrome (CRPS)
Efficacy and Safety of Intravenous Neridronic Acid in Complex Regional Pain Syndrome (CRPS)
The aim of this trial was to investigate the efficacy and safety of intravenous neridronic acid in subjects with Complex Regional Pain Syndrome (CRPS).
- Trial name
- NCT03560986
- Testing
- Neridronic acid 100 mg
- Where
- 71 sites in United States, Canada and 5 more
- Volunteers
- 267 people
- Sponsor
- Grünenthal GmbH
Complex Regional Pain Syndrome Type I, Complex Regional Pain Syndrome Type II
Neurotropin to Treat Chronic Neuropathic Pain
This study will examine the effectiveness of the drug neurotropin in treating chronic pain after injury to a limb or a large nerve.
- Trial name
- NCT00006289
- Testing
- Neurotropin
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- National Institute of Nursing Research (NINR)
Reflex Sympathetic Dystrophy
Investigation of the Efficacy of tDCS in the Treatment of Complex Regional Pain Syndrome (CRPS) Type 1
The efficacy of the current standard non-pharmacological treatments for complex regional pain syndrome (CRPS), a painful syndrome mostly occurring after musculoskeletal trauma, is suboptimal.
- Trial name
- NCT01960400
- Testing
- Graded motor imagery (GMI)
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- Université de Sherbrooke
Chronic Pain, Neuropathic Pain
Intraoperative Neuromonitoring Recording With a Novel SCS Paddle
The purpose of this study is to demonstrate safety and efficacy of a new spinal cord stimulation paddle electrode which is able to target the dorsal horns, dorsal nerve roots, and dorsal columns.
- Conditions
- Chronic Pain, Neuropathic Pain, Failed Back Surgery Syndrome, Complex Regional Pain Syndromes
- Trial name
- NCT05045625
- Testing
- HD Study Electrode
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Albany Medical College
Pain
A Pilot Study of Switching From One Pain Medication to Another (Opioid Rotation)
The purpose of this study is to see if changing from one pain medication like morphine or oxycodone to another pain medication, oxymorphone (OPANA®), will be helpful to patients.
- Trial name
- NCT00580294
- Testing
- Oxymorphone
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Complex Regional Pain Syndrome (CRPS)
TMS for CRPS - Pilot Study
The purpose of this pilot study is to test whether Transcranial Magnetic Stimulation (TMS) may alleviate the symptoms of Complex Regional Pain Syndrome (CRPS).
- Trial name
- NCT01926119
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Stanford University
Pain
The Effect of Intravenous Lidocaine on Allodynia
The purpose of this study is to study if lidocaine, given intravenously, reduces pain.
- Trial name
- NCT00659633
- Testing
- lidocaine
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Alabama at Birmingham
Neuralgia, Postherpetic Neuralgia
Effects of Pennsaid on Clinical Neuropathic Pain
The purpose of this study is to see if the drug Pennsaid (Diclofenac) can help reduce pain felt by people with chronic nerve pain. The drug will be used 2-4 times each day for 2 weeks. The U.S.
- Conditions
- Neuralgia, Postherpetic Neuralgia, Reflex Sympathetic Dystrophy, Complex Regional Pain Syndrome (CRPS)
- Trial name
- NCT01508676
- Testing
- Pennsaid
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Massachusetts General Hospital
Pain
Clonidine Versus Adenosine to Treat Neuropathic Pain
The purpose of this study is to determine the effects of clonidine and adenosine on nerve pain.
- Trial name
- NCT00349921
- Testing
- clonidine, adenosine
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Wake Forest University Health Sciences
Anxiety Disorders, Complex Regional Pain Syndrome Type II
Regional Anesthesia Military Battlefield Pain Outcomes Study
The purpose of this study is to examine the short and long-term benefits of implementing early regional anesthesia techniques for pain control after a major traumatic injury to one or more extremities during combat in the…
- Conditions
- Anxiety Disorders, Complex Regional Pain Syndrome Type II, Depressive Disorders, Post-Traumatic Stress Disorder
- Trial name
- RAMBPOS (NCT00431847)
- Testing
- Regional Anesthesia, Standard Pain Management Protocol
- Where
- 3 sites in United States
- Volunteers
- 386 people
- Sponsor
- VA Office of Research and Development
Pain
The Effect of Intravenous Lidocaine on Normal Sensation and Pain in Healthy Volunteers
The purpose of this study is to study if lidocaine, given intravenously, reduces pain.
- Trial name
- NCT00657358
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Complex Regional Pain Syndrome
Safety of Intravenous Neridronic Acid in CRPS
The aim of this trial was to investigate the safety of intravenous neridronic acid in patients with complex regional pain syndrome (CRPS).
- Trial name
- NCT02972359
- Testing
- Neridronic acid
- Where
- 46 sites in United States, Germany
- Volunteers
- 580 people
- Sponsor
- Grünenthal GmbH
Complex Regional Pain Syndrome (CRPS)
Transcranial Magnetic Stimulation (TMS) for CRPS
The purpose of this pilot study is to test the durability of response to Transcranial Magnetic Stimulation (TMS) for the symptoms of Complex Regional Pain Syndrome (CRPS).
- Trial name
- NCT02067273
- Testing
- Transcranial Magnetic Stimulation (TMS)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Stanford University
Complex Regional Pain Syndrome (CRPS)
TARGET Post-Approval Study
The purpose of this prospective, multicenter, single arm post-approval study is to demonstrate continued safety of the Axium and Proclaim Neurostimulator System for dorsal root ganglion (DRG) stimulation.
- Trial name
- TARGET PAS (NCT02800863)
- Testing
- Dorsal Root Ganglion (DRG) Stimulation (Axium™ Neurostimulator System), Dorsal Root Ganglion (DRG) Stimulation (Proclaim™ Neurostimulator System)
- Where
- 44 sites in United States
- Volunteers
- 426 people
- Sponsor
- Abbott Medical Devices
Chronic Pain, Low Back Pain
High Frequency Stimulation Trials in Patients With Precision Spinal Cord Stimulator System
Study designed to compare the conventional stimulation programming versus the high frequency stimulation programming of the spinal cord stimulator for subjects who already have a spinal cord stimulator.
- Conditions
- Chronic Pain, Low Back Pain, Radiculopathy, Complex Regional Pain Syndrome (CRPS)
- Trial name
- HFSCS (NCT02265848)
- Testing
- High frequency stimulation, Low frequency stimulation
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- The Center for Clinical Research, Winston-Salem, NC
Osteoarthritis, Rheumatoid Arthritis
Double-Blind Follow-on Safety Study of HZT-501 (Ibuprofen 800 mg/Famotidine 26.6 mg) in Subjects Who Have Completed Participation in HZ-CA-301 (NCT00450658) or HZ-CA-303 (NCT00450216)
The purpose of this study is to evaluate the safety of long-term treatment with HZT-501.
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Chronic Low Back Pain, Chronic Regional Pain Syndrome
- Trial name
- HZ-CA-304 (NCT00613106)
- Testing
- HZT-501, Ibuprofen
- Where
- United States
- Volunteers
- 179 people
- Sponsor
- Amgen
Cancer
Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain
This is a phase III, randomized, double-blind, placebo-controlled, multicenter study of the clinical response to fentanyl sublingual spray as a treatment for breakthrough cancer pain.
- Trial name
- NCT00538850
- Testing
- Fentanyl sublingual spray
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- INSYS Therapeutics Inc
CRPS
Prospective, Randomized Controlled Trial on Perioperative Pregabalin to Reduce Late-onset CRPS After TKA
The Department of Anesthesiology is conducting a clinical trial to evaluate if pregabalin given prior to and for several days after Total Knee Arthroplasty (TKA) will reduce the prevalence of Complex Regional Pain Syndrome (CRPS)…
- Trial name
- PregTKA (NCT00558753)
- Testing
- pregabalin
- Volunteers
- 240 people
- Sponsor
- Rush University Medical Center
Amplified Musculoskeletal Pain Syndrome, Reflex Sympathetic Dystrophy
Audio-Visual Relaxation Technology for Pediatric Amplified Musculoskeletal Pain Syndrome
A pilot randomized controlled trial to assess feasibility, acceptability and generate outcome domains for a future RCT testing the efficacy of immersive virtual reality on pain intensity in pediatric amplified musculoskeletal…
- Conditions
- Amplified Musculoskeletal Pain Syndrome, Reflex Sympathetic Dystrophy, Complex Regional Pain Syndromes
- Trial name
- NCT03762213
- Testing
- Oculus GO VR HMD, application Happy Place (© Mimerse), iPad, application Happy Place (© Mimerse)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Tufts Medical Center