Clinical trials: Compliance, Medication
Comorbidity, Medication Therapy Management
Team Approach to Polypharmacy Evaluation and Reduction
In an aging population, most seniors suffer from multiple chronic conditions. When the number of medications taken is ≥5 (polypharmacy), the burden of taking so many together can do more harm than good.
- Trial name
- TAPER (NCT02562352)
- Testing
- TAPER program
- Where
- Canada
- Volunteers
- 38 people
- Sponsor
- McMaster University
Adherence
A Universal Medication Schedule to Promote Adherence to Complex Drug Regimens
This study will leverage available technologies and test strategies to impart the Universal Medication Schedule (UMS) in primary care to help patients understand, consolidate, safely use, and adhere to their complex medication…
- Trial name
- NCT02820753
- Testing
- EHR + (Text or Portal)
- Where
- United States
- Volunteers
- 677 people
- Sponsor
- Northwestern University
Chronic Disease, Obesity
Active and Healthy Brotherhood: A Program for Chronic Disease Self-Management for Black Men
This study will test ways to improve health behaviors using an intervention that has been specially designed for African-American men.
- Conditions
- Chronic Disease, Obesity, Hypertension, Diabetes
- Trial name
- NCT02362737
- Testing
- Active and Healthy Brotherhood (AHB)
- Where
- United States
- Volunteers
- 332 people, healthy volunteers welcome
- Sponsor
- Gramercy Research Group
Medication Adherence
Development and Evaluation of an Electronic Health Record-based Medication Complete Communication (EMC2) Strategy
There is a well-documented need for effective interventions that can help patients understand and safely adhere to prescribed medications, particularly those with greater potential for harm if not taken correctly.
- Trial name
- NCT03652272
- Testing
- EMC2
- Where
- United States
- Volunteers
- 301 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Medication Nonadherence, Depression
The Effectiveness of CBI on Depression and Adherence in HIV Infected Adolescents
Aim: To explore the effectiveness of psychoeducation and problem-solving (Life-steps) on depression and adherence in HIV-infected adolescents.
- Conditions
- Medication Nonadherence, Depression, HIV Infections
- Trial name
- NCT05482217
- Testing
- Psychoeducation, problem solving and rehearsal (cognitive behavioural intervention)
- Where
- Botswana
- Volunteers
- 25 people
- Sponsor
- University of Botswana
Stroke, Transient Ischemic Attack
Tailored Intervention to Improve Patient Adherence to Secondary Stroke Prevention Medication
Patient suffering a Transient Ischemic Attack (TIA) or stroke are subsequently at high risk of a new stroke, however, poor adherence to secondary prevention medications occurs frequently within this patient group.
- Trial name
- NCT01684176
- Testing
- Complex tailored intervention, Usual care
- Where
- Denmark
- Volunteers
- 211 people
- Sponsor
- Odense University Hospital
Schizophrenia, Psychotic Disorders
Medication Adherence in Schizophrenia: Development of a CBT-Based Intervention
This is a randomized pilot study of an intervention based on principles of Cognitive Behavioral Therapy (CBT). This intervention is the Health Dialogue Intervention (HDI) and will be compared to a traditional medical model of…
- Trial name
- NCT00980252
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Illinois Chicago
Medication Adherence, Medication Compliance
MITIGAAT: Multifaceted Intervention To Improve Graft Outcome Disparities in African American Kidney Transplants
This is a randomized study to test a smartphone app that a pharmacist will use to help kidney transplant patients track their medications, blood pressures, and blood sugars in those with diabetes.
- Trial name
- NCT06023615
- Testing
- mHealth app/dashboard
- Where
- United States
- Volunteers
- 190 people
- Sponsor
- Medical University of South Carolina
Hypercholesterolemia, Medication Adherence
Pilot Program to Improve Statin Adherence and Lower Cholesterol in Older Adults
The purpose of this study is to pilot test a behavioral medication adherence (MA) intervention compared to control condition in older adults with low adherence to medication for hypercholesterolemia.
- Trial name
- NCT01227330
- Testing
- Medication adherence intervention, Attention-control
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- University of Missouri-Columbia
Risk Behavior, HIV/AIDS
Testing an Integrated Bio-Behavioral Primary HIV Prevention Intervention Among High-Risk People Who Use Drugs
This study will evaluate the efficacy and cost-effectiveness of CHRP-BB - an integrated bio-behavioral approach that incorporates the use of PrEP - with an evidence-based behavioral approach aimed at enhancing PrEP adherence and…
- Conditions
- Risk Behavior, HIV/AIDS, Medication Adherence, Substance Abuse
- Trial name
- CHRP-BB (NCT03282890)
- Testing
- CHRP-BB
- Where
- United States
- Volunteers
- 237 people
- Sponsor
- University of Connecticut
Migraine Headache
Effectiveness of Education and Relaxation Program on Migraine Related Disability in Patients Attending Headache Clinic
Migraine causes severe impairment in quality of life (QOL) both during and between attacks. Migraine also increases absenteeism, reduces productivity at work as well as at home, disrupts social and family relationships, also is…
- Trial name
- NCT05039996
- Testing
- education and relaxation program
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Adrenergic Beta-Antagonists, Stable Angina Pectoris
A Randomized, Two-arm, Open Label Study to evalUate the Effect of a Smart Phone-based Patient Support Tool On Patient AdheRence of Treatment in Stable Angina Patients Prescribed Beta-blockers in China (SUPPORT)
The present study aims to enhance the adherence of beta-blockers by Patient Support Tool through a smart phone application and a wristband, subsequently reduce the risk of angina attacks in patients with stable angina pectoris.
- Conditions
- Adrenergic Beta-Antagonists, Stable Angina Pectoris, Medication Adherence, Mobile Applications
- Trial name
- NCT03794713
- Testing
- Patient support tool
- Volunteers
- 432 people
- Sponsor
- Shenyang Northern Hospital
Hypertension
The Multicenter Randomized HYpertension and VALUEs (HYVALUE) Trial
The objective of this study is to reduce the effects of stereotype threat on the adherence of African American patients with hypertension.
- Trial name
- HYVALUE (NCT03028597)
- Testing
- Intervention Values Affirmation, Control Values Affirmation
- Where
- 3 sites in United States
- Volunteers
- 960 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Cardiovascular Diseases
Patients With Acute Myocardial Infarction
Aims and objectives The aim of this study was to determine whether planned discharge training given by the nurse has an impact on beliefs about cardiovascular disease risk factors knowledge level, compliance to drug therapy…
- Trial name
- NCT03985397
- Testing
- discharge training
- Volunteers
- 100 people
- Sponsor
- Manisa Celal Bayar University
Diabetes Mellitus, Type 2
Dulce Digital-Me: An Adaptive mHealth Intervention for Underserved Hispanics With Diabetes
This study will compare Dulce Digital (i.e., the investigators' proven-effective combination of "one-size-fits-all" educational text messages and nurse monitoring of patient-transmitted blood glucose values) and Dulce Digital-Me…
- Trial name
- DD-Me (NCT03130699)
- Testing
- Dulce Digital, Dulce Digital-Me (Automated Delivery), Dulce Digital-Me (Medical Assistant)
- Where
- 2 sites in United States
- Volunteers
- 310 people
- Sponsor
- Scripps Whittier Diabetes Institute
Polypharmacy, Multimorbidity
A Multidisciplinary Intervention Including a Clinical Decision Support System and an App for Drug Therapy Management in Older Patients
"La Casa nel Parco" (CANP) Project is a European Union and Regione Piemonte funded multidisciplinary project aimed to explore innovative technology application in older subject care.
- Conditions
- Polypharmacy, Multimorbidity, Aged
- Trial name
- FARMA-CANP (NCT04391218)
- Testing
- Multidisciplinary Approach Group
- Volunteers
- 89 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Medication Adherence
Improving Adherence to Pharmacological Treatment
The overall goal of this study was to implement and evaluate the effects of a systems-based and pharmacist-mediated program designed to improve adherence for patients with known coronary heart disease (CHD) to lipid-lowering…
- Trial name
- PACT (NCT00848224)
- Testing
- systems-based and pharmacist-mediated program
- Where
- United States
- Volunteers
- 689 people
- Sponsor
- University of Massachusetts, Worcester
Diabetes Mellitus
Diabetes Self-Management Educational Program
Diabetes mellitus is the third most prevalent chronic disease globally. It is a metabolic disorder characterized by elevated blood glucose because of impaired insulin production, reduced insulin effectiveness, or both.
- Trial name
- DSMEP (NCT05581264)
- Testing
- Diabetes Self-Management Education Program
- Where
- Jordan
- Volunteers
- 200 people
- Sponsor
- Mutah University
Diabetes Mellitus, Type 2
The Effectiveness of Diabetes Patient Education and Self-Management Education in Persons With Type 2 Diabetes
The goal of this randomized controlled trial is to determine if greater effectiveness can be achieved by the addition of lay-led self-management patient education to regular professionally-led diabetes patient education in…
- Trial name
- NCT00906919
- Testing
- Regular diabetes patient education, Augmented diabetes patient education
- Where
- Canada
- Volunteers
- 321 people
- Sponsor
- University of Victoria
HIV, Medication Adherence
mHealth Facilitated Intervention to Improve Medication Adherence Among Persons Living With HIV
HIV medications can be very effective at helping patients have longer, healthier lives. However, many patients do not take their HIV medications as prescribed.
- Conditions
- HIV, Medication Adherence, Telemedicine
- Trial name
- Super SMART (NCT05046392)
- Testing
- Face-to-Face ART Adherence Intervention, Carium Mobile Health Platform
- Where
- 2 sites in United States
- Volunteers
- 400 people
- Sponsor
- Rhode Island Hospital
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