Clinical trials: Compliance, Patient
Covid-19, Critical Illness
Understanding Community Considerations, Opinions, Values, Impacts, and Decisions for COVID-19
The novel coronavirus (COVID-19) is affecting the way many people live their lives, including seeking medical care and maintaining good self-care to keep healthy.
- Conditions
- Covid-19, Critical Illness, Attitude of Health Personnel, Attitude to Health
- Trial name
- UC-COVID (NCT04373135)
- Testing
- Brief educational video
- Where
- United States
- Volunteers
- 1,971 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Medication Adherence, Retention in Care
An Avatar-based Mobile Phone Intervention to Promote Health in African American MSM
The investigators propose to determine the efficacy of "My Personal Health Guide," a theory-based innovative talking relational human Avatar mobile phone application to engage HIV-positive AAMSM in adherence and retention in…
- Trial name
- NCT04217174
- Testing
- My Personal Health Guide, My Personal Food Guide
- Where
- United States
- Volunteers
- 315 people
- Sponsor
- University of Illinois Chicago
Type 2 Diabetes Mellitus, Fear of Hypoglycemia
Effects of a Health Intervention on Fear of Hypoglycemia : a Pilot Study
The purpose of this study was to construct a Fear of Hypoglycemia(FoH) intervention program for type 2 diabetic patients based on the Behaviour Change Wheel (BCW) theory and to investigate the feasibility, acceptability, and…
- Conditions
- Type 2 Diabetes Mellitus, Fear of Hypoglycemia, Health Education, Impaired Awareness of Hypoglycemia
- Trial name
- NCT06197360
- Testing
- Based on BCW Theory of Health Education, General diabetes health education
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Yangzhou University
Heart Disease, Mental Health Outcomes
The Feasibility of an Intervention Targeting Sources of Meaning in Cardiac Rehabilitation
Being diagnosed with heart disease can be a life-changing experience, often sparking existential questions and concerns about meaning in life.
- Conditions
- Heart Disease, Mental Health Outcomes, Rehabilitation
- Trial name
- NCT07262580
- Testing
- Conversation on Sources of Meaning in life with heart disease, Group based session on Sources of Meaning in life with heart disease, Dyadic Conversation on Sources of Meaning in Life with heart disease
- Where
- 2 sites in Denmark
- Volunteers
- 80 people
- Sponsor
- University of Southern Denmark
Postpartum Hemorrhage, Postpartum Depression
Postpartum Video Education in High Risk Populations
This is a prospective, single-center, randomized control study to determine if video education at the time of postpartum discharge improves patient knowledge on the warning signs for the top three causes of severe maternal…
- Conditions
- Postpartum Hemorrhage, Postpartum Depression, Postpartum Sepsis, Postpartum Preeclampsia
- Trial name
- NCT06310720
- Testing
- Video Education
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Obstructive Sleep Apnea (OSAS)
Night Balance for Positional Obstructive Sleep Apnea Syndrome (POSAS)
POSAS can be treated with CPAP however there is now evidence from a few studies that Night Balance is effective in POSAS. Night Balance seems to be better accepted than CPAP so we would like to examine if we could find similar…
- Trial name
- POSAS (NCT02114424)
- Testing
- Positional vibrator belt
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Glostrup University Hospital, Copenhagen
Vaccine Hesitancy
Motivational Interviewing and Vaccine Hesitancy in Children
This study will assess the effectiveness of a motivational interviewing-based tool in addressing vaccine hesitancy expressed by parents or caregivers of children.
- Trial name
- MOTIVE (NCT03934008)
- Testing
- MOtivational interviewing Tool to Improve Vaccine AdherencE (MOTIVE)
- Where
- United States
- Volunteers
- 4,191 people, healthy volunteers welcome
- Sponsor
- Cedarville University
Essential Hypertension
Repurposing Colchicine to Improve Vascular Function in Hypertension
In this project the potential beneficial effect of the drug colchicine on vascular reactivity and blood pressure will be assessed.
- Trial name
- RECTIFHY (NCT04303689)
- Testing
- Colchicine Tablets
- Where
- Denmark
- Volunteers
- 31 people
- Sponsor
- University of Copenhagen
HIV Infections
Directly Observed Therapy for HIV Infected Adolescents
Adherence to a doctor-prescribed anti-HIV drug regimen is crucial in the management of HIV infection. In previous studies with tuberculosis patients, directly observed therapy (DOT), a strategy in which patients are observed…
- Trial name
- NCT00259389
- Testing
- Directly observed therapy (DOT)
- Where
- 6 sites in United States
- Volunteers
- 24 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Schizophrenia
Effect of Genotyping for CYP450 Polymorphisms Versus Intense Clinical Monitoring on Antipsychotic Drug Treatment
The purpose of this study is to determine whether genotyping for CYP2D6 and 2C19 polymorphisms or intense clinical monitoring of treatment and adverse effects improves the antipsychotic treatment in patients with schizophrenia.
- Trial name
- NCT00707382
- Testing
- (1) Genotyping for CYP4502D6 and 2C19 polymorphisms, (2) Intense clinical monitoring, (3) Control
- Where
- Denmark
- Volunteers
- 311 people
- Sponsor
- Gesche Jurgens
Patient Compliance, Inhalation Spacers
Animated Cartoons and Cooperation in Young Children Receiving Inhaled Medications
Up to 50% of infants and young children cry during the administration of their inhaled treatment for their asthma. This results in decreased lung deposition, and thus decreased effectiveness of their inhaled treatment.
- Trial name
- DISTRACT (NCT02879240)
- Testing
- Animated Cartoon, Black screen
- Where
- 3 sites in France
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Hôpital Necker-Enfants Malades
Stroke
Preventing Recurrence of Thromboembolic Events Through Coordinated Treatment in the District of Columbia
The purpose of this study is to refine and evaluate the Preventing Recurrence of Thromboembolic Events through Coordinated Treatment in the District of Columbia (PROTECT DC) intervention.
- Trial name
- PROTECT DC (NCT00703274)
- Testing
- PROTECT DC
- Where
- 6 sites in United States
- Volunteers
- 230 people
- Sponsor
- Georgetown University
Cancer, Bone Marrow Neoplasms
The PRISM Intervention for Adolescents and Young Adults Receiving Hematopoietic Cell Transplantation
Multisite Randomized Controlled Trial (RCT) testing the efficacy of the Promoting Resilience in Stress Management (PRISM) intervention among Adolescents and Young Adults receiving hematopoietic cell transplantation for hematology…
- Conditions
- Cancer, Bone Marrow Neoplasms, Anxiety, Depression
- Trial name
- NCT03640325
- Testing
- PRISM (Promoting Resilience in Stress Management)
- Where
- 5 sites in United States
- Volunteers
- 143 people
- Sponsor
- Seattle Children's Hospital
Visceral (Hyper)Sensitivity
The Effects of Butyrate Enemas on Visceral Perception
During this double blind, placebo controlled, randomised cross over study, healthy volunteers received an enema once daily for one week containing either placebo (saline), 50mM butyrate or 100mM of butyrate.
- Trial name
- NCT00726817
- Testing
- Butyrate
- Where
- Netherlands
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Medication Compliance, Medication Adherence
Thinking Outside the Box
Medication adherence - the extent to which a patient takes their medications as prescribed - is a global problem. Half of all medicines given to patients with long-term health problems are not taken properly by the patient.
- Conditions
- Medication Compliance, Medication Adherence, Caregivers, Attitude
- Trial name
- NCT04713215
- Testing
- Questionnaire
- Where
- United Kingdom
- Volunteers
- 176 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Urologic Diseases, Prostate Cancer
Intravesical Antifibrinolytic for Patients With Hematuria and Clot Retention
A study looking at the feasibility of doing a full-scale RCT that investigates the use of tranexamic acid intravesically prior to continuous bladder irrigation treatment in the emergency department for urinary retention due to…
- Conditions
- Urologic Diseases, Prostate Cancer, Bladder Cancer, Urinary Retention
- Trial name
- NCT04555343
- Testing
- Tranexamic acid
- Where
- 2 sites in Canada
- Volunteers
- 14 people
- Sponsor
- Fraser Health
Esophageal Varices Bleeding
The Compliance and Prognosis of NSBB Secondary Prevention of Cirrhosis With Gastroesophageal Varices Bleeding
Non-selective beta blockers are commonly used drugs for primary prevention and secondary prevention in patients with cirrhotic decompensated esophageal varices bleeding，the basic heart rate, blood pressure and condition of…
- Trial name
- NCT03683121
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Renmin Hospital of Wuhan University
Chronic Non-specific Low-Back Pain, Chronic Non-specific Neck Pain
Diaphragmatic Breathing Training in Chronic Spinal Pain
The goal of this clinical trial is to learn whether adding breathing training to an exercise program can improve pain, mood, and thinking skills in adults with chronic spinal pain.
- Trial name
- NCT07539116
- Testing
- Structured Exercise program, Diaphragmatic Breathing Training
- Where
- 2 sites in Greece
- Volunteers
- 183 people
- Sponsor
- Democritus University of Thrace
Borderline Personality Disorder
Long Term Follow-up of Mentalization-Based Treatment: Exploring Variability in Outcomes, Long-term Value and Experiences 10+ Year After Receiving MBT Day Hospital or MBT Intensive Outpatient
This study is a long-term follow-up study of a previous multicenter randomized controlled trial, in which n=114 participants were included.
- Trial name
- MBT-EVOLVE (NCT07509216)
- Where
- 2 sites in Netherlands
- Volunteers
- 113 people
- Sponsor
- De Viersprong
Spinal Cord Injuries
Enhanced Medical Rehabilitation for Spinal Cord Injury
Background: Patient engagement is a cornerstone of patient-centered care. Studies show that an increased level of patient engagement in medical rehabilitation is associated with greater functional recovery.
- Trial name
- EMRSCI (NCT03952416)
- Testing
- Enhanced Medical Rehabilitation (EMR)
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Shirley Ryan AbilityLab