Clinical trials: Complication Laparoscopic Cholecystectomy
Acute Cholecystitis, Postoperative Pain
Irrigation of Bupivacaine at the Surgical Bed for Postoperative Pain Relief After Laparoscopic Cholecystectomy for Acute Cholecystitis
This study aims to compare the effectiveness of irrigation of 0.5% bupivacaine versus normal saline at the gallbladder surgical bed in reducing postoperative pain following laparoscopic cholecystectomy for acute cholecystitis.
- Trial name
- NCT07851935
- Testing
- Bupivacaine 0.5%, Normal Saline 0.9%
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- Ziauddin University
Pain, Postoperative
Comparison of the Efficacy and Safety of NALDEBAIN With Conventional Treatment After Laparoscopic Cholecystectomy
To determine the effect and safety of NALDEBAIN versus Morphine as needed in patients after laparoscopic cholecystectomy.
- Trial name
- NCT03713216
- Testing
- Naldebain, Morphine
- Where
- Taiwan
- Volunteers
- 44 people
- Sponsor
- Cathay General Hospital
Preemptive Peripheral Nerve Block, Pain, Postoperative
Preemptive Analgesic Effects of Rectus Sheath Block in Laparoscopic Cholecystectomy Patients
The purpose of this study was to investigate the effectiveness of preemptive effect of rectus sheath block (RSB) and intercostal nerve block (ICNB) on postoperative visceral pain in laparoscopic cholecystectomy (LLC).
- Conditions
- Preemptive Peripheral Nerve Block, Pain, Postoperative, Acute Pain
- Trial name
- NCT03413280
- Testing
- Ultrasound guided Rectus sheath block, Intercostal nerve block
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Asan Medical Center
Intertransverse Process Block, Mtapa Block
Intertransverse Process Block Versus M-TAPA Block After Laparoscopic Cholecystectomy
This randomized clinical trial aims to evaluate and compare the analgesic efficacy of the Intertransverse Process Block (ITPB) and the Modified Thoracoabdominal Nerve Block through Perichondrial Approach (M-TAPA) in patients…
- Conditions
- Intertransverse Process Block, Mtapa Block, Laparoscopic Cholecystectomy, Postoperative Pain
- Trial name
- NCT07589491
- Testing
- Intertransverse Process Block, M-TAPA Block
- Volunteers
- 60 people
- Sponsor
- Antalya City Hospital
Postoperative Nausea and Vomiting
Metoclopramide-Ondansetron vs. Metoclopramide Therapy for Treatment of Nausea and Vomiting Post Laparoscopic Surgery
The incidence of postoperative nausea and vomiting (PONV) after general anesthesia is up to 30% when inhalational anesthetics are used with no prophylaxis.
- Trial name
- NCT03459248
- Testing
- Dual therapy, Monotherapy, General anesthesia
- Where
- Lebanon
- Volunteers
- 120 people
- Sponsor
- Makassed General Hospital
Cholecystitis, Acute, Cholelithiasis
Acupuncture for Prevention of Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy
The purpose is to find out if intraoperative acupuncture performed by needling PC 6 and LI4 point bilaterally, and Yin Tang point will help reduce the incidence postoperative nausea and vomiting in patients undergoing…
- Conditions
- Cholecystitis, Acute, Cholelithiasis, Nausea, Postoperative, Vomiting, Postoperative
- Trial name
- NCT05975385
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- Baylor College of Medicine
Acute Cholecystitis, Biliary Complications
Acute Cholecystitis Biliary Complications - ICG
Acute cholecystitis is a common indication for emergency laparoscopic cholecystectomy. Inflammatory changes and distorted anatomy may increase the risk of biliary complications, including bile duct injury and bile leak, which are…
- Trial name
- ICG-ACBC (NCT07481760)
- Testing
- ICG
- Where
- Spain
- Volunteers
- 296 people
- Sponsor
- Hospital del Mar
Gall Stone, Gallbladder Inflammation
Benchmarks in Elective Laparoscopic Cholecystectomy
The aim of this observational cohort study is to define peri- and postoperative reference values for elective laparoscopic cholecystectomy, using the achievable benchmarks of care methodology (ABC™).
- Conditions
- Gall Stone, Gallbladder Inflammation, Gall Bladder Pain, Gallstone
- Trial name
- NCT06692517
- Testing
- Laparoscopic cholecystectomy
- Volunteers
- 60,000 people
- Sponsor
- Region Östergötland
Pain, Postoperative, Postoperative Nausea and Vomiting
Effect of Pulmonary Recruitment Maneuver (PRM) on Pain and Nausea After Laparoscopic Cholecystectomy
This prospective, blinded, randomized clinical trial investigates the effect on postoperative pain and nausea, when performing a ventilator-piloted PRM at the end of a laparoscopic cholecystectomy.
- Trial name
- NCT03026543
- Testing
- Pulmonary Recruitment Maneuver, Laparoscopic cholecystectomy, Ventilator
- Where
- Sweden
- Volunteers
- 260 people
- Sponsor
- Region Östergötland
Cholelithiasis (Without Cholecystitis), Pain, Postoperative
Video-assisted Umbilical Fascial Closure in Laparoscopic Cholecystectomy
A prospective randomized study was performed including consecutive patients who underwent an elective laparoscopic cholecystectomy (LC) for symptomatic cholelithiasis during the 18 months period.
- Conditions
- Cholelithiasis (Without Cholecystitis), Pain, Postoperative, Hernia Incisional
- Trial name
- NCT05208385
- Testing
- video-assisted umbilical closure
- Where
- Turkey (Türkiye)
- Volunteers
- 240 people
- Sponsor
- Samsun Education and Research Hospital
Cholecystitis, Pain
The Effect of Hyoscine-n-butylbromide on Nausea and Pain in Laparoscopic Cholecystectomy
The goal of this randomized double blind study is to compare the effects of hyoscine-n-butylbromide, and ondansetron on postoperative nausea-vomiting, and pain in patients who underwent laparoscopic cholecystectomy.The main…
- Conditions
- Cholecystitis, Pain, Nausea
- Trial name
- NCT06927817
- Testing
- hyoscine-n-butylbromide, ondansetron, • hyoscine-n-butylbromide • ondansetron
- Where
- Turkey (Türkiye)
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Postoperative Pain, Acute
Effectiveness of Fentanyl-Added TAP Block in Laparoscopic Cholecystectomy
The aim of this study is to evaluate the effectiveness of adding fentanyl to the TAP block in laparoscopic cholecystectomy cases.
- Trial name
- NCT06778668
- Testing
- TAP block with bupivacaine only, TAP block with bupivacaine and fentanyl
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Uludag University
Pain, Postoperative
Duloxetine for Postoperative Pain of Laparoscopic Cholecystectomy
Recent studies on the impact of perioperative duloxetine for treatment of acute postoperative pain have yielded positive outcomes with respect to reduction opioid consumption.
- Trial name
- NCT05115123
- Testing
- Duloxetine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Cholelithiasis
Incisional Hernia Rate After Single-incision Laparoscopic Cholecystectomy
Single-incision laparoscopic cholecystectomy (SILC) requires a larger incision than standard laparoscopy, which may increase the incidence of incisional hernias.
- Trial name
- NCT03768661
- Testing
- Single-incision Laparoscopic cholecystectomy, Laparoscopic Cholecystectomy
- Where
- Spain
- Volunteers
- 185 people
- Sponsor
- Hospital Plató
Cholelithiasis, Cholecystectomy, Laparoscopic
Unilateral Laparoscopic TAP Block vs. Local Infiltration in Post-Cholecystectomy Analgesia
This study compared different methods of pain control after laparoscopic gallbladder removal. A total of 160 patients were randomly assigned to receive either a unilateral laparoscopic TAP block, local anesthetic infiltration, a…
- Conditions
- Cholelithiasis, Cholecystectomy, Laparoscopic, Pain, Postoperative, Anesthesia, Local
- Trial name
- TAP vs LAI (NCT07176299)
- Testing
- Unilateral laparoscopic TAP block (0.25% bupivacaine), Local anesthetic infiltration (0.25% bupivacaine), Combined TAP block and local anesthetic infiltration (0.25% bupivacaine)
- Where
- Poland
- Volunteers
- 160 people
- Sponsor
- University of Warmia and Mazury in Olsztyn
Acute Pain, Postoperative Pain
Comparison of the Effectiveness of Preemptive Paracetamol and Ibuprofen in Acute Postoperative Pain
This study will evaluate two different analgesic regimen used for acute postoperative pain.
- Trial name
- NCT03063658
- Testing
- Paracetamol, Ibuprofen 800 mg
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Ankara University
Quality of Recovery, Postoperative Pain
Quality of Recovery Under Low or Standard Pneumoperitoneum Pressure
The use of low-pressure pneumoperitoneum seems to be able to reduce complications such as postoperative pain. However, the quality of evidence for most studies evaluating this relationship is considered low.
- Conditions
- Quality of Recovery, Postoperative Pain, Postoperative Nausea and Vomiting, Neuromuscular Blockade
- Trial name
- NCT05040022
- Testing
- Pneumoperitoneum pressure 10 mmHg, Pneumoperitoneum pressure 14 mmHg
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Pontificia Universidade Catolica de Sao Paulo
Postoperative Pain, Laparoscopic Cholecystectomy
Optimal Patient Positioning for Erector Spinae Plane Block in Laparoscopic Cholecystectomy:
This randomized clinical study aims to compare the postoperative analgesic efficacy, analgesic consumption, and patient satisfaction of erector spinae plane (ESP) block administered in three different patient positions-lateral…
- Conditions
- Postoperative Pain, Laparoscopic Cholecystectomy, Anesthesia, Regional, Pain Management
- Trial name
- ESP-POSTURE (NCT07018258)
- Testing
- Erector Spinae Plane (ESP) Block
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Harran University
Postoperative Pain, Cholelithiasis
Comparative Efficacy of ESPB and EOPB for Postoperative Analgesia in Laparoscopic Cholecystectomy: A Randomized Controlled Trial (External Oblique Intercostal Plan Block (EOPB) and Erector Spina Plan Block (ESPB) )
This randomized controlled clinical trial investigates the comparative efficacy of two novel regional anesthesia techniques - the Erector Spinae Plane Block (ESPB) and the External Oblique Intercostal Plane Block (EOPB) - for…
- Conditions
- Postoperative Pain, Cholelithiasis, Acute Pain
- Trial name
- NCT07057934
- Testing
- ESPB Block, EOPB Block, Standard Systemic Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Pain, Postoperative, Postoperative Nausea and Vomiting
Single Port Versus Four Ports Laparoscopic Cholecystectomy and Early Postoperative Pain
This is a trial to evaluate if single port laparoscopic cholecystectomy causes less pain than conventional laparoscopic cholecystectomy.
- Conditions
- Pain, Postoperative, Postoperative Nausea and Vomiting, Postoperative Complications
- Trial name
- UMBI-CHOL (NCT01268748)
- Testing
- Conventional laparoscopic procedure, Experimental laparoscopic procedure
- Where
- 3 sites in Denmark
- Volunteers
- 120 people
- Sponsor
- Bispebjerg Hospital