Clinical trials: Complication of Anesthesia
Emergence Delirium, Anesthesia, Preschool Age Children
Influence of Intraoperative Auditory Intervention on Emergence Delirium in Preschoolers: A Randomised Controlled Clinical Trial
Emergence delirium (ED), characterized by disorientation and altered cognitive behavior, is a common postoperative complication in pediatric surgery.
- Conditions
- Emergence Delirium, Anesthesia, Preschool Age Children, Emergence Agitation
- Trial name
- NCT07630922
- Testing
- Classical Music Group, Mother's Heartbeat Recording Group, Mother's Lullaby Recording Group
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Henan Provincial People's Hospital
Transurethral Resection of Prostate
Effectiveness of Nalbuphine as an Adjuvant to Subarachnoid Block on Postoperative Analgesia in TURP Surgery
The goal of this clinical trial is to compare pain after surgery in patients undergoing Transurethral Resection of Prostate. The main question it aims to answer are: Intrathecal nalbuphine as an adjuvant to local anesthetic will…
- Trial name
- NCT06153602
- Testing
- Nalbuphine Hydrochloride 10 MG/ML, Sodium Chloride 0.9 % in 5 ML Injection, Bupivacaine Hydrochloride, Spinal
- Where
- Thailand
- Volunteers
- 80 people
- Sponsor
- Chulalongkorn University
Adenotonsillectomy, Preoperative Anxiety
Timing Of Midazolam İn Children Undergoing Adenotonsillectomy: Effects On Stress, Cortisol, And Recovery
This study is a prospective, randomized, controlled clinical trial designed to evaluate the optimal timing of midazolam administration in children undergoing adenotonsillectomy.
- Conditions
- Adenotonsillectomy, Preoperative Anxiety, Surgical Stress Response, Postoperative Pain
- Trial name
- Timing-Midazol (NCT07622641)
- Testing
- Midazolam (Oral), Midazolam (Intravenous)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Erzurum City Hospital
Emergence Agitation
Comparison Between Propofol and Fentanyl for Prevention of Emergence Agitation in Children After Sevoflurane Anesthesia
The occurrence of emergence agitation (EA) in pediatric patients who have received sevoflurane anesthesia is a common postoperative problem.
- Trial name
- NCT01506622
- Testing
- Administration of propofol, Administration of fentanyl, Administration of saline
- Where
- South Korea
- Volunteers
- 222 people
- Sponsor
- Yonsei University
Post-Operative Confusion, Long Term Adverse Effects
Depth of Anaesthesia and Long-term Survival: The Balanced Anaesthesia Follow-up Study
Anaesthetic depth and complications after major surgery: an international, randomised controlled trial - The BALANCED trial. In this large, international, randomised controlled trial that enrolled patients aged 60 years and over…
- Conditions
- Post-Operative Confusion, Long Term Adverse Effects, Surgery--Complications, Cognitive Dysfunction, Postoperative
- Trial name
- BALANCEDLT (NCT04965324)
- Testing
- Anaesthesia Depth
- Where
- New Zealand
- Volunteers
- 6,644 people
- Sponsor
- Auckland City Hospital
Female Sexual Dysfunction, Endometrial Sampling
Assessment of Female Sexual Function Index (FSFI) Scores at 1 Month After Endometrial Sampling Performed Under Sedo-Analgesia or Local Anesthesia
Endometrial sampling is a commonly performed gynecological procedure used for the diagnosis of abnormal uterine bleeding and endometrial abnormalities.
- Conditions
- Female Sexual Dysfunction, Endometrial Sampling, Female Sexual Function Index (FSFI), Abnormal Uterine Bleeding, Unspecified
- Trial name
- FSFI-ENDO (NCT07628660)
- Where
- Turkey (Türkiye)
- Volunteers
- 210 people
- Sponsor
- Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
İnguinal Hernia, Post Operative Pain
Comparison of QLB and TFP Block for Postoperative Analgesia in Laparoscopic Inguinal Hernia
This randomized controlled trial aims to compare the effects of ultrasound-guided lateral Quadratus Lumborum Block (QLB) and Transversalis Fascia Plane (TFP) block on postoperative analgesia in patients undergoing laparoscopic…
- Trial name
- NCT07604259
- Testing
- Lateral Quadratus Lumborum Block, Transversalis Fascia Plane Block, Port Site Infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Medipol University
Pain, Postoperative, Inguinal Hernia Unilateral
Intrathecal Morphine and Transversalis Fascia Plane Block for Analgesia After Open Inguinal Hernia Repair
Inguinal hernia is a common surgical condition, and open inguinal hernia repair may be associated with significant postoperative pain.
- Conditions
- Pain, Postoperative, Inguinal Hernia Unilateral, Intrathecal Morphine, Transversalis Fascia Plane Block
- Trial name
- NCT07826741
- Testing
- Intrathecal Morphine Group, Transversalis Fascia Plane Block Group, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Atatürk Chest Diseases and Chest Surgery Training and Research Hospital
Vaping, Complication of Anesthesia
Perioperative Vaping Complications
Prospective observational study evaluating the incidence, and qualifying the types, of perioperative pulmonary complications in patients that vape.
- Trial name
- NCT05912023
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Navy Medical Center San Diego
OSAHS, Gastrointestinal Endoscopy
Observation of Clinical Effect of New Oropharyngeal Airway in Patients With OSHAS During Painless Gastroenteroscopy
the(obstructivesleepapneahypoapneasyndromeOSAHS) is a kind of to sleep appear periodically in the process of syndrome characterized by partial or complete obstruction of upper respiratory tract.Patients with obstruction during…
- Conditions
- OSAHS, Gastrointestinal Endoscopy, Airway Complication of Anesthesia
- Trial name
- NCT06594380
- Testing
- Group using new oropharyngeal airway (experimental group), Endoscopic bite group (control group)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Jianbo Wu
Tracheostomy Complication, Emergency Front of Neck Airway in Children
Neck Rescue Access Comparison
Emergency front-of-neck access (eFONA) represents the final lifesaving intervention in a pediatric "can't intubate, can't oxygenate" scenario.
- Conditions
- Tracheostomy Complication, Emergency Front of Neck Airway in Children, Anesthesia
- Trial name
- eFONA (NCT07368179)
- Testing
- Percutaneous Seldinger-Guided Tracheal Access (Melker), scalpel-bougie tracheostomy
- Where
- Switzerland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Kidney Stones, Nephrolithiasis
Comparison of Different Ventilation Modes for Reducing Kidney Motion During Retrograde Intrarenal Surgery
This randomized clinical trial will compare four ventilation strategies during retrograde intrarenal surgery performed under general anesthesia.
- Trial name
- RIRS-VENT (NCT07705646)
- Testing
- Standard Ventilation, Hypoventilation, Intermittent Apnea Ventilation
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Benign Prostate Hyperplasia, Bladder Tumor
Effective Dose of Dexmedetomidine for Sedation in Patients Undergoing TURP/TURB Under Spinal Anesthesia With or Without Fentanyl by Age Groups: Randomized Comparative Study
Recently many studies reported that intraoperative dexmedetomidine administration undergoing spinal anesthesia give a satisfactory sedation in elderly patients and cause less respiratory depressions compared other sedatives(e.g.
- Trial name
- NCT01665586
- Testing
- dexmedetomidine
- Where
- South Korea
- Volunteers
- 82 people
- Sponsor
- Yonsei University
Postoperative Pain, Adults
Safety and Efficacy Evaluation of S (+) - Ketamine in Adults
A multicenter, randomized, open-label, active controlled pragmatic clinical trial that evaluates the safety and efficacy of S (+) -ketamine for postoperative acute pain in adults in perioperative settings.
- Conditions
- Postoperative Pain, Adults, Anesthesia
- Trial name
- NCT04837170
- Testing
- Conventional therapy + S (+)-Ketamine, Conventional therapy
- Volunteers
- 12,000 people
- Sponsor
- Chinese PLA General Hospital
Postoperative Pain, Laparoscopic Cholecystectomy
Erector Spinae Plane Block and Low-Flow Anaesthesia in Laparoscopic Cholecystectomy
This prospective randomized controlled study aims to evaluate the effects of preoperative ultrasound-guided erector spinae plane (ESP) block combined with low-flow anaesthesia on postoperative quality of recovery and opioid…
- Trial name
- NCT07653490
- Testing
- Erector Spinae Plane Block, Low Fresh Gas Flow (0.5 L/min), Standard Fresh Gas Flow (3 L/min)
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Taksim Egitim ve Arastirma Hastanesi
Airway Complication of Anesthesia
Utilization of Airway Stabilizing Rod
The pediatric airway is known to be more challenging than the adult airway when performing endotracheal intubation. When a patient cannot be ventilated and/or intubated, the guidelines for airway management dictate that a…
- Trial name
- FASTER (NCT05899868)
- Testing
- Time to Intubation using FASTER device
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Baylor College of Medicine
Prostate Cancer, Bladder Cancer
Mannitol Versus Nitroglycerin for Kidney Injury Prevention in Robotic-assisted Radical Prostatectomy or Cystectomy
Laparoscopic and minimally-invasive robotic access has transformed the delivery of urological surgery. While associated with numerous desirable outcomes including shorter post-operative stay and faster return to preoperative…
- Conditions
- Prostate Cancer, Bladder Cancer, Surgery, Renal Impairment
- Trial name
- NCT06408597
- Testing
- Nitroglycerin Infusion, Mannitol Infusion, Fluid Regimen
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Nazmy Edward Seif
Kidney Failure, Chronic
Creation of Arteriovenous Ante-brachial Fistula Under Axillary Block Versus Local Anesthesia : Impact on Early Complications
Recommended by the KDOQI vascular access guidelines, antebrachial arteriovenous fistula is the best primary vascular access for hemodialysis in patients with end stage renal disease.
- Trial name
- FAV ss ALR (NCT02722096)
- Testing
- Axillary block anesthesia with Ropivacaine and Lidocaine, Local anesthesia with Ropivacaine and Lidocaine
- Where
- France
- Volunteers
- 78 people
- Sponsor
- Hospices Civils de Lyon
Postoperative Pain, Postoperative Nausea and Vomiting
The Effect of Pharyngeal Cooling Applications on Postoperative Throat Pain and Nausea Vomiting
The goal of this observational study is to to evaluate the effects of a throat pack soaked with saline at +4 ºC on postoperative throat pain (POTP) and postoperative nausea and vomiting (PONV) in dental surgical procedures…
- Conditions
- Postoperative Pain, Postoperative Nausea and Vomiting, Throat, Sore, Anesthesia
- Trial name
- NCT06271161
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Postoperative Pain, Opioid Use
Continuous Serratus Anterior Blockade for Sternotomy
This is a pilot study to assess the feasibility of a full study. The purpose is to assess the analgesic effectiveness of the serratus anterior plane (SAP) block following cardiac surgery.
- Conditions
- Postoperative Pain, Opioid Use, Quality of Life
- Trial name
- Cardiac-SAP (NCT04648774)
- Testing
- Serratus anterior plane (SAP) block
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Nova Scotia Health Authority