Clinical trials: Complication of Diagnostic Procedure
Reconstructive Surgical Procedures, Tissue Transplantation
Monitoring of Tissue Transfer Flaps by Modulated Imaging (MI) Spectroscopy
Tissue transfer flaps are a method of moving tissue from a donor location to a recipient location. In the case of a free tissue transfer flaps, the blood vessels to the transferred tissues are detached and then re-attached to…
- Trial name
- NCT00633503
- Where
- 2 sites in United States
- Volunteers
- 26 people
- Sponsor
- University of California, Irvine
Atherosclerosis, Chronic Kidney Diseases
The ILERVAS Project: Assessing the Prevalence of Subclinical Vascular Disease and Hidden Kidney Disease
BACKGROUND AND OBJECTIVES: Cardiovascular disease is the leading cause of death despite huge primary and secondary prevention policies with a strong economic burden.
- Conditions
- Atherosclerosis, Chronic Kidney Diseases, Metabolic Syndrome, PreDiabetes
- Trial name
- ILERVAS (NCT03228459)
- Testing
- Dried blood spot test, Urine test, Artery ultrasound
- Where
- 3 sites in Spain
- Volunteers
- 16,660 people
- Sponsor
- Institut de Recerca Biomèdica de Lleida
High Risk Infant, Neurodevelopmental Disorder (Diagnosis)
SAFE Early Intervention for At-Risk Infants
This randomized controlled study aims to investigate the effects of the SAFE early intervention approach on upper extremity function, fine motor skills, and developmental outcomes in high-risk infants aged 3-12 months.
- Conditions
- High Risk Infant, Neurodevelopmental Disorder (Diagnosis), Preterm
- Trial name
- SAFE-EFFECT (NCT07596147)
- Testing
- SAFE Early Intervention Program, NDT TREATMENT
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Gazi University
Epithelial Ovarian Cancer
Real-world Study of Niraparib Maintenance Treatment in Patients With Newly Diagnosed Ovarian Cancer
This is an open-label, single-arm, multi-center、non-interventional real-world study, which evaluate treatment pattern, safety and efficacy of Niraparib as first-line maintenance treatment for Chinese patient with newly diagnosed…
- Trial name
- RENI-1 (NCT04986371)
- Testing
- Niraparib
- Volunteers
- 300 people
- Sponsor
- Ling-Ying Wu
Lung Cancer, Bladder Cancer
Intervention Protocol for Automated Point-of-Care Surveillance of Outpatient Delays in Cancer Diagnosis
Many missed and delayed cancer diagnoses result from breakdowns in communication and coordination of abnormal findings suspicious for cancer, which often first emerge in the primary care setting.
- Conditions
- Lung Cancer, Bladder Cancer, Colorectal Cancer, Hepatocellular Carcinoma
- Trial name
- PACT CREATE 3 (NCT01710293)
- Testing
- Communication of Patients Lost to Follow-up to Providers
- Where
- 5 sites in United States
- Sponsor
- VA Office of Research and Development
Homocysteine, Coronary Disease
The Relationship Between HHcy and Contrast-induced Nephropathy in Hypertensive Patients After Coronary Artery Diagnosis and Treatment
Contrast-induced nephropathy has become the third-largest cause of hospital acquired acute renal injury, and which morbidity is only less than that of renal hypoperfusion and renal toxicity of drugs, about 11%of all cases.
- Conditions
- Homocysteine, Coronary Disease, Angioplasty,Balloon,Coronary, Contrast Media
- Trial name
- CONTRAST-CADT (NCT02575092)
- Testing
- Enalapril Maleate Tablets(as the program-based antihypertension), Enalapril Maleate and Folic Acid tablets(as the program-based antihypertension)
- Where
- China
- Volunteers
- 4,000 people
- Sponsor
- Fuling Central Hospital of Chongqing City
Indocyanine Green (ICG), Robotic Surgical Procedure
Assessing the Efficacy of Indocyanine Green for Ureter Identification During Robot-Assisted Surgery in Advanced-Stage Endometriosis
The goal of this side-randomized, self-controlled trial, 1-site study is to explore the efficacy of Indocyanine Green Fluorescence (ICG) for Intraoperative Ureter Identification During Robot-Assisted Single-Site Surgery in…
- Conditions
- Indocyanine Green (ICG), Robotic Surgical Procedure, Deep Infiltrating Endometriosis (DIE), Endometriosis Pelvic
- Trial name
- NCT07144904
- Testing
- Indocyanine Green (ICG)-Assisted Ureteral Identification, Standard Ureteral Identification without ICG
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Baylor College of Medicine
Polycystic Ovary Syndrome
Multimodal Ocular Diagnosis-Guided Precision Acupuncture and Lifestyle Intervention for PCOS
This study is designed as a prospective, multicenter, parallel-group randomized controlled trial to evaluate the effectiveness of a "precision acupuncture + personalized lifestyle" intervention, guided by dynamic multimodal risk…
- Trial name
- NCT07809503
- Testing
- Model-Guided Precision Acupuncture, Personalized Lifestyle Intervention, Conventional Acupuncture
- Where
- 2 sites in China
- Volunteers
- 210 people
- Sponsor
- Peking University Third Hospital
Preeclampsia
CercaTest™ Red Urine Test for Predicting Preeclampsia
The goal of this observational study is to predict preeclampsia in pregnant women aged 18 years or older with a singleton pregnancy at 20 or more weeks of gestation who present with suspected signs or symptoms of preeclampsia.
- Trial name
- PRE-CERCA (NCT07625501)
- Where
- Hong Kong
- Volunteers
- 1,000 people
- Sponsor
- Chinese University of Hong Kong
Proteinuria, Preeclampsia
Validation of a PrCr Dipstick Diagnostic Test in Ghana
This evaluation will aim to generate a body of evidence that will determine performance characteristics of the current PrCr dipstick test and the feasibility of its use in target ANC settings.
- Trial name
- NCT03510286
- Testing
- Test-it™ PrCr Urinalysis Strips
- Where
- Ghana
- Volunteers
- 1,483 people, healthy volunteers welcome
- Sponsor
- PATH
Fetal Conditions, Maternal; Procedure
A Prospective Study on the Role of Karl Storz Curved and Straight Fetoscopes (11508AAK and 11506AAK) for Fetoscopic Intrauterine Procedures
In this research study, the investigators want to learn more about the role of new innovative surgical devices, the Karl Storz Curved and Straight Fetoscopes for in-utero surgery.
- Conditions
- Fetal Conditions, Maternal; Procedure, Pregnancy Related, Twin to Twin Transfusion Syndrome
- Trial name
- NCT06056635
- Testing
- Karl Storz Curved Scope, Karl Storz Straight Scope
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Boston Children's Hospital
Heart Defects, Congenital, Anxiety in Pregnancy
HeartGPS: A Study Exploring the Effects of a Psychological Intervention for Parents and Their Babies After Prenatal Cardiac Diagnosis
Babies with single ventricle congenital heart disease (SVCHD) are often diagnosed during pregnancy. While prenatal diagnosis has important clinical benefits, it is often stressful and overwhelming for parents, and many express a…
- Conditions
- Heart Defects, Congenital, Anxiety in Pregnancy, Depression, Postpartum, Trauma, Psychological
- Trial name
- HeartGPS (NCT06175104)
- Testing
- HeartGPS
- Where
- 4 sites in United States, Australia
- Volunteers
- 50 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Urinary Tract Infection(UTI), Antimicrobial Stewardship
Diagnostic Stewardship Intervention to Reduce Inappropriate Antibiotic Use for Urinary Tract Infections in Primary Care
Urine culture is the most common microbiological test in the outpatient setting in the United States. Unfortunately, contamination during collection is prevalent and undermines test accuracy, leading to incorrect diagnosis…
- Conditions
- Urinary Tract Infection(UTI), Antimicrobial Stewardship, Primary Care
- Trial name
- NCT07246837
- Testing
- MSCC Educational Tool
- Where
- United States
- Volunteers
- 252 people
- Sponsor
- Baylor College of Medicine
Prostate Cancer, Benign Prostatic Hypertrophy
Evaluation of the NV-VPAC1 Prostate Cancer (PCa) Urine Diagnostic Test in Subjects With Biopsy-confirmed Prostate Cancer, Benign Prostatic Hypertrophy, or Bladder/Kidney Stones.
This is a double-blind, study to evaluate the performance of NV-VPAC1 PCa Urine Diagnostic Test in three distinct populations being treated at the Intermountain Urology Clinic.
- Conditions
- Prostate Cancer, Benign Prostatic Hypertrophy, Bladder Stones, Kidney Stones
- Trial name
- VPAC (NCT03630926)
- Testing
- NV-VPAC1 PCa Urine Diagnostic Test
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Intermountain Health Care, Inc.
Breast Cancer, Colon Cancer
EXoPERT EMERALD Clinical Study
The purpose of this study is to establish a multi-center clinical repository of blood samples to support the development and evaluation of an artificial intelligence-based in vitro diagnostic software.
- Conditions
- Breast Cancer, Colon Cancer, Pancreatic Cancer, Ovarian Cancer
- Trial name
- NCT07186296
- Testing
- EXoPred
- Where
- 9 sites in United States
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- EXoPERT
Menorrhagia
Relationship Between Bladder Distention and Hysteroscopy Application
The purpose of the study is to investigate the advantages and disadvantages of bladder filling during hysteroscopy procedure.
- Trial name
- NCT01848847
- Testing
- Hysteroscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Namik Kemal University
Diabetes Mellitus - Type 1, Diabetes Mellitus - Type 2
The BRIGHT Study (Device Name: HALO System)
The purpose of the BRIGHT study is to evaluate safety and performance of the HALO SYSTEM in subjects with diabetes mellitus. The primary objectives of this clinical investigation are 1) the evaluation of sensor's performance by…
- Conditions
- Diabetes Mellitus - Type 1, Diabetes Mellitus - Type 2, Diabetes Mellitus, Ketoacidosis, Diabetic
- Trial name
- NCT07745998
- Testing
- The HALO System
- Volunteers
- 12 people
- Sponsor
- Indigo Diabetes NV
Thoracic Cancer, Ovarian Cancer
Project CADENCE (CAncer Detected Early caN be CurEd)
With existing evidence showing the difference in miRNA expression levels between non-cancer and cancer groups, the investigators assume that levels of DNA methylation, RNA expression as well as protein concentration will also be…
- Conditions
- Thoracic Cancer, Ovarian Cancer, Liver Cancer, Prostate Cancer
- Trial name
- CADENCE (NCT05633342)
- Where
- Singapore
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- MiRXES Pte Ltd
Bladder Tumor
Assessment of the Uro-C Cystoscope for Use in Diagnostic Cystoscopy Procedures
This is a prospective, multicenter, single-arm, open-label clinical usability study in subjects who are candidates for office diagnostic cystoscopy.
- Trial name
- NCT03331705
- Testing
- Uro-C (Use of new cystoscope)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- UroSee Corporation
Neoplasm, Colorectal, Neoplasm of Lung
Preventing Viral Pandemic Associated Risk of Cancer Death Using Less Invasive Diagnostic Tests- Liquid Biopsies
The purpose of this study is to investigate the feasibility of using ctDNA to support cancer diagnosis and risk stratification where invasive aerosol generating testing (and/or tissue biopsy) is challenging due to infection risk…
- Conditions
- Neoplasm, Colorectal, Neoplasm of Lung, Neoplasm, Bladder, Neoplasms Pancreatic
- Trial name
- PREVAILctDNA (NCT04566614)
- Testing
- ctDNA blood sampling
- Where
- United Kingdom
- Volunteers
- 128 people
- Sponsor
- Royal Marsden NHS Foundation Trust