Clinical trials: Complication of Dialysis
Chronic Renal Failure
Serum Uremic Toxins and Histological Findings of the Blood Vessels in Dialysis Patients
Patients treated by chronic renal replacement therapy are exposed to cardiovascular problems and suffer from an accelerated and sever atherosclerosis.
- Trial name
- NCT00412139
- Where
- North Macedonia
- Volunteers
- 100 people
- Sponsor
- University of Skopje
Acute Kidney Injury
Pharmacokinetics of Vancomycin in the ICU in Renal Replacement Therapy
This study is an observational analysis that monitors the effect of different dialysis methods on vancomycin levels when patients are critically ill.
- Trial name
- NCT00848809
- Testing
- Blood sample
- Where
- United States
- Sponsor
- Avera McKennan Hospital & University Health Center
Anemia, Chronic Kidney Disease
Safety, PD & PK of Multiple Doses of Peginesatide for Anemia in Chronic Kidney Disease Patients
The purpose of this study was to evaluate the safety, pharmacodynamics (PD), and pharmacokinetics (PK) of multiple subcutaneous injections of peginesatide in participants with chronic kidney disease (CKD) not on dialysis who had…
- Conditions
- Anemia, Chronic Kidney Disease, Chronic Renal Failure
- Trial name
- NCT00228436
- Testing
- peginesatide
- Where
- 13 sites in Poland, United Kingdom
- Volunteers
- 139 people
- Sponsor
- Affymax
Hypotension, End Stage Renal Disease
Pharmacokinetic and Pharmacodynamic Effects of MTR107 in End-Stage Renal Disease (ESRD) Patients
MTR107 effect on blood pressure throught the dialysis procedure and its ability to prevent Intra dialytic Hypotension
- Conditions
- Hypotension, End Stage Renal Disease, Intra Dialytic Hypotension
- Trial name
- NCT00448071
- Testing
- MTR107
- Where
- 2 sites in Israel
- Volunteers
- 12 people
- Sponsor
- Wolfson Medical Center
End-Stage Renal Disease
Vitamin D3 Supplementation in Dialysis Patients
Vitamin D deficiency is highly prevalent among dialysis patients, and has been associated with cardiovascular risk factors such as increased aortic pulse wave velocity, blood pressure, inflammation, and brain natriuretic peptide.
- Trial name
- NCT01312714
- Testing
- Cholecalciferol
- Where
- Denmark
- Volunteers
- 64 people
- Sponsor
- Regional Hospital Holstebro
Chronic Renal Failure, Anemia
Safety & Efficacy of Pegolsihematide for Treatment of Anemia in Participants on Dialysis
The purpose of this study is to evaluate the safety and efficacy of multiple intravenous doses of pegol-Sihematide in participants with chronic kidney disease (CKD) who are on dialysis.
- Conditions
- Chronic Renal Failure, Anemia, Dialysis
- Trial name
- NCT02586402
- Testing
- pegol-Sihematide, Epoetin Alfa
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Jiangsu Hansoh Pharmaceutical Co., Ltd.
Complication of Dialysis, Thrombus Due to Renal Dialysis Device, Implant, or Graft
Cerebral Microembolism During Hemodialysis
There is increasing evidence that renal replacement therapy (= continuous veno-venous hemodialysis) generates cerebral microembolism which is detectable on transcranial Doppler ultrasound.
- Conditions
- Complication of Dialysis, Thrombus Due to Renal Dialysis Device, Implant, or Graft, Cerebral Embolism
- Trial name
- NCT02021045
- Testing
- Renal hemodialysis (Fresenius 2008K, Bad Homburg, Germany)
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- Medical University of Vienna
Acute Kidney Injury
Automated Peritoneal Dialysis Versus Intermittent Hemodialysis in Acute Kidney Injury
This is a multi-center randomized clinical trial study. The purpose of this study is to examine safety, feasibility and efficacy of automated peritoneal dialysis as compared with intermittent hemodialysis for AKI patients with…
- Trial name
- SAFE-APD (NCT03598387)
- Testing
- Automated peritoneal dialysis, Intermittent hemodialysis
- Where
- 5 sites in China
- Volunteers
- 100 people
- Sponsor
- Limeng Chen
RENAL INSUFFICIENCY, CHRONIC, Hyperparathyroidism, Secondary
Evaluation of Colecalciferol Substitution in Dialysis Patients
The purpose of this study is to determine the effect of a colecalciferol substitution in dialysis patients on bone metabolism and immune system
- Trial name
- NCT00397475
- Testing
- Colecalciferol
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- University Hospital, Saarland
Renal Insufficiency, Chronic, Anxiety
AI-Guided Personalized Relaxation for Hemodialysis Patients
Patients undergoing maintenance hemodialysis frequently experience impaired health-related quality of life, anxiety, and difficulties in coping with the long-term demands of treatment.
- Conditions
- Renal Insufficiency, Chronic, Anxiety, Relaxation Therapy, Maintenance Hemodialysis
- Trial name
- NCT07522944
- Testing
- AI-Guided Relaxation Platform, Standard Hemodialysis Nursing Care
- Where
- Egypt
- Volunteers
- 128 people
- Sponsor
- Alexandria University
End Stage Renal Failure on Dialysis, Complication of Dialysis
A Prospective Study of Airless Tubing in an Inpatient Acute Hemodialysis Unit in Hospitalized Patients
The introduction of unfractionated heparin (UFH), which prevents clotting of the extracorporal circuit, was one of the key advances that led to the rapid development and expansion of hemodialysis services.
- Conditions
- End Stage Renal Failure on Dialysis, Complication of Dialysis, Blood Coagulation Disorders
- Trial name
- NCT02086682
- Where
- United States
- Volunteers
- 338 people
- Sponsor
- Marie Hogan
Chronic Kidney Disease
Pharmacokinetic/Pharmacodynamic Parameters of NNG-DEPO (Stimus) With Aranesp® (Amgen) in Treatment of Anemia in CKD Patients on Dialysis
This is a double-blind, randomized, active-control study with 2-study arms-darbepoetin alfa biosimilar and Aranesp, noninferiority trial design in dialysis patients.
- Trial name
- CKD (NCT05636891)
- Testing
- Stimus
- Where
- Vietnam
- Volunteers
- 43 people
- Sponsor
- Nanogen Pharmaceutical Biotechnology Joint Stock Company
Chronic Kidney Disease, Dialysis
A Study of MCI-196 in Chronic Kidney Disease Subjects on Dialysis With Hyperphosphatemia and Dyslipidaemia
This is a phase III multi-centre study in two periods: the first period is a phosphate binder and lipid lowering drugs washout for 8 weeks, the second period is a double-blind, randomised, parallel group, fixed dose, for 12 weeks.
- Conditions
- Chronic Kidney Disease, Dialysis, Hyperphosphatemia, Dyslipidemia
- Trial name
- NCT00542386
- Testing
- MCI-196
- Where
- 73 sites in Hungary, Italy and 6 more
- Volunteers
- 642 people
- Sponsor
- Tanabe Pharma Corporation
Chronic Kidney Disease
Study of the Compliance With Phosphorus Restricted Diet and Phosphate Binder Therapy in Hemodialysis Patients
Hyperphosphatemia is a common and severe complication in chronic kidney disease patients treated with hemodialysis. A phosphate restricted diet and oral phosphate binders are the cornerstones in the prevention and treatment of…
- Trial name
- NCT01509027
- Testing
- education by DVD, Standard care, Education by DVD and dietician
- Where
- Belgium
- Volunteers
- 150 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Peritoneal Dialysis Associated Peritonitis, Peritoneal Dialysis (PD)
Pharmacokinetics of Meropenem and Aztreonam After Intraperitoneal Administration Via Cycler-therapy in APD Patients Without Peritonitis
Peritoneal dialysis-associated peritonitis (PDAP) remains one of the most serious complications in patients undergoing peritoneal dialysis (PD), contributing significantly to hospitalization, technique failure, and mortality.
- Conditions
- Peritoneal Dialysis Associated Peritonitis, Peritoneal Dialysis (PD), Peritoneal Dialysis, Peritoneal Dialysis, Continuous Ambulatory
- Trial name
- NCT07113574
- Testing
- Meropenem 1000 mg, Aztreonam 2000 mg, automated peritoneal dialysis with following long time dwell
- Where
- Austria
- Volunteers
- 12 people
- Sponsor
- Karl Landsteiner Insitute for Nephrology and Haemato-Oncology
Dialysis Access Malfunction, Kidney Failure
Evaluation of Paclitaxel Coated Balloon in the Treatment of Dialysis Access Dysfunction
Recent studies of paclitaxel DCB in the treatment of stenosis at dialysis vascular access have shown promising results. Paclitaxel, an anti-proliferation drug, is released during balloon inflation and potentially improve primary…
- Trial name
- NCT04988789
- Testing
- Paclitaxel Drug Coated Balloon
- Where
- Singapore
- Volunteers
- 500 people
- Sponsor
- Singapore General Hospital
Renal Failure
Music Intervention for Dialysis Patients
The goal of this clinical trial is to examine the efficacy of both live and pre-recorded music interventions on alleviating the negative effects of dialysis treatment.
- Trial name
- NCT06478524
- Testing
- Live music, Pre-recorded music
- Where
- 2 sites in Singapore
- Volunteers
- 102 people
- Sponsor
- National University of Singapore
Chronic Kidney Diseases, Cardiovascular Diseases
Assessment of Protein Modification in Chronic Kidney Disease - Selected Clinical and Biochemical Aspects
The studies included the effect of chronic kidney disease advancement on the accumulation of oxidative stress markers in plasma. In patients with end-stage renal disease, the effect of replacement therapy was also assessed.
- Conditions
- Chronic Kidney Diseases, Cardiovascular Diseases, Dialysis; Complications
- Trial name
- NCT04939870
- Testing
- Biochemical parameters evaluation
- Where
- Poland
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- Poznan University of Medical Sciences
Chronic Kidney Failure, Renal Dialysis
Health Related Quality of Life and Cognitive Function Among Norwegian Dialysis Patients
The purpose of this study is to assess health related quality of life and its predictors among chronic dialysis patients and to assess cognitive function using 3 different tests.
- Trial name
- NCT00806130
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Norwegian University of Science and Technology
Kidney Failure
FREquent DIalysis & Markers of Cardiac Strain and Injury, Physical Fitness, Habitual Physical Activity & Quality of Life
Individuals with kidney failure are kept alive using dialysis machines designed to remove toxic substances and excess fluid from the blood.
- Trial name
- FREDI-CAL (NCT03925454)
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Portsmouth Hospitals NHS Trust
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