Clinical trials: Complication of Dialysis
Hyperkalemia, Chronic Kidney Disease Requiring Chronic Dialysis
Effect of Viscous Fiber on Postprandial Kalemic Response in Hemodialysis Patients
High blood potassium levels (hyperkalemia) is a major problem for people with kidney failure undergoing hemodialysis treatment. In order to reduce the risk of hyperkalemia, people with kidney failure are advised to limit or avoid…
- Trial name
- NCT05086185
- Testing
- Kalemic Response to Orange Juice, Kalemic Response to Orange Juice with Fiber
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Nevada, Reno
Renal Osteodystrophy, End Stage Renal Disease
Phase II Randomized Study of the Effects of Growth Hormone on Children and Adolescents on Maintenance Dialysis
OBJECTIVES: I. Evaluate the separate and combined skeletal effects of recombinant human growth hormone (GH) and calcitriol in patients with adynamic renal osteodystrophy. II.
- Trial name
- NCT00004340
- Testing
- calcitriol, growth hormone
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- National Center for Research Resources (NCRR)
Chronic Kidney Disease, Dialysis
Long-term Extension Study of MCI-196
The Primary Objectives of this study are to assess the long-term efficacy of treatment with colestilan (MCI-196) (including combination therapy) and to assess the long-term safety of treatment with colestilan (MCI-196) (including…
- Conditions
- Chronic Kidney Disease, Dialysis, Hyperphosphatemia, Paediatric
- Trial name
- NCT01814917
- Testing
- colestilan, CBPB
- Where
- United Kingdom
- Volunteers
- 6 people
- Sponsor
- Tanabe Pharma Corporation
Chronic Kidney Disease (CKD)
Retrospective Analysis Assessing Clinical Risk Factors for Cardiovascular Events and Mortality and Development of a Risk Calculator in Chronic Kidney Disease Stage 5 on Dialysis
The purpose of this study is to evaluate which clinical and laboratory factors are associated with major adverse cardiovascular event (MACE) in chronic kidney disease (CKD) patients on dialysis.
- Trial name
- NCT04042350
- Testing
- Non-interventional
- Where
- Sweden
- Volunteers
- 2,773 people
- Sponsor
- Astellas Pharma Europe Ltd.
Renal Insufficiency, Chronic
Impact of Physical Activity on Patients With Chronic Kidney Disease Not Receiving Dialysis Followed in the TIRCEL Network. An Exposed / Unexposed Study (PHYSALYS)
PHYSALYS is an observational multicenter study. It's an analytical study comparing 2 groups: patients exposed to physical activity and unexposed.
- Trial name
- PHYSALYS (NCT02818010)
- Testing
- Global Physical Activity Questionnaire
- Volunteers
- 259 people
- Sponsor
- Hospices Civils de Lyon
End-stage Renal Disease, Kidney Failure, Chronic
Evaluation of the Safety and Efficacy of a Vascular Prosthesis for Hemodialysis Access in Patients With ESRD
The purpose of this study is to assess the safety and efficacy of a novel, tissue-engineered vascular prosthesis, the Human Acellular Vascular Graft, HAVG.
- Trial name
- NCT01744418
- Testing
- HAVG graft implantation
- Where
- 3 sites in Poland
- Volunteers
- 40 people
- Sponsor
- Humacyte, Inc.
Vascular Diseases, Kidney Diseases
Drug Eluting Balloon (DEB) vs Plain Old Balloon Angioplasty (POBA) in the Treatment of Failing Dialysis Access
Background Conventional percutaneous transluminal angioplasty is still considered standard treatment for treatment of dysfunctional haemodialysis fistulas and grafts.
- Trial name
- NCT05173857
- Testing
- Advance PTX, Advance LP (Low Profile), Paclitaxel (PTX)
- Volunteers
- 42 people
- Sponsor
- Skane University Hospital
Acute Renal Failure
Furosemide in Early Acute Kidney Injury
Acute renal failure, now referred to as acute kidney injury, is common in intensive care unit patients, contributes to high morbidity and mortality, and has no proven interventions with benefit once established.
- Trial name
- SPARK (NCT00978354)
- Testing
- Furosemide, Normal Saline
- Where
- 4 sites in Australia, Canada
- Volunteers
- 72 people
- Sponsor
- University of Alberta
Renal Disease, End Stage
β2M Post-HD Rebound Prediction
β2-Microglobulin is small 11.8 kDa protein presents on the surface of all nucleated cell in the human body, it forms part of the non-variable chain of Major Histocompatibility Complex class I.
- Trial name
- NCT07713680
- Testing
- β2-microglobulin blood concentration in mg/L
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- East and North Hertfordshire NHS Trust
Oral Disease, Chronic Kidney Diseases
Prevalence of Oral Findings in Chronic Kidney Disease
There are severe deficiency of database concerning the oral health status in both pre-dialysis and end stage renal disease in Egyptian population.
- Trial name
- NCT03074188
- Volunteers
- 225 people
- Sponsor
- Alaa Mostafa Hassan Elnaggar
End Stage Renal Failure, Hemodialysis
Exploring Predictors of Quality of Life in Older Adults With End-Stage Kidney Disease Receiving In-Center Hemodialysis
This cross-sectional observational study investigates the overall quality of life (QoL) in adults aged 65 and older receiving in-center hemodialysis.
- Trial name
- B670201837264 (NCT07129083)
- Testing
- Structured assessment interview
- Where
- Belgium
- Volunteers
- 111 people
- Sponsor
- University Ghent
Acute Kidney Injury
Standard Versus Accelerated Initiation of Dialysis in Acute Kidney Injury
The objectives of this trial are to determine whether, in critically ill patients with severe acute kidney injury (AKI), randomization to accelerated initiation of renal replacement therapy (RRT), compared with standard…
- Trial name
- STARRT-AKI (NCT01557361)
- Testing
- Accelerated RRT initiation, Standard RRT initiation
- Where
- 11 sites in Canada
- Volunteers
- 100 people
- Sponsor
- Unity Health Toronto
Inflammation, Chronic Kidney Disease
Role of Prohepcidin in Uremic Patients
The investigators aimed to study the effect of prohepcidin levels on hematologic parameters and inflammatory markers in non-diabetic uremic patients.
- Trial name
- NCT01735773
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Haseki Training and Research Hospital
Peritoneal Dialysis Complication, Constipation
Evaluation of the Impact of Transit Troubles in Patients Undergoing Peritoneal Dialysis
Patients with Terminal Chronic Kidney Disease undergoing Peritoneal Dialysis (PD) often have pathophysiological factors that promote chronic constipation.
- Trial name
- TransDiPe (NCT04102527)
- Testing
- Questionnaires
- Where
- France
- Volunteers
- 180 people
- Sponsor
- Centre Hospitalier de Vichy
Chronic Kidney Disease Requiring Chronic Dialysis
A Study to Assess the Tolerability of Oxylanthanum Carbonate in Patients With Chronic Kidney Disease on Dialysis
The goal of this clinical study is to test the tolerability of oxylanthanum carbonate (OLC) in patients with chronic kidney disease on hemodialysis and have hyperphosphatemia (too much phosphorus in their blood).
- Trial name
- NCT06218290
- Testing
- Oxylanthanum Carbonate
- Where
- 7 sites in United States
- Volunteers
- 106 people
- Sponsor
- Unicycive Therapeutics, Inc
Anemia
FG-4592 for Treatment of Anemia in Subjects With Chronic Kidney Disease Not on Dialysis
This is a randomized, multicenter, double-blind, placebo-controlled study of the treatment of anemia in subjects with CKD not on dialysis, with treatment up to 52 weeks.
- Trial name
- NCT02652819
- Testing
- FG-4592
- Where
- 30 sites in China
- Volunteers
- 154 people
- Sponsor
- Kyntra Bio
Chronic Kidney Disease Stage 3, Anemia
Desidustat in the Treatment of Anemia in CKD
This is a phase III, multicenter, multi-country, open-label, randomized, active-controlled clinical trial to evaluate the efficacy and safety of Desidustat versus Darbepoetin for the treatment of anemia in patients with CKD who…
- Conditions
- Chronic Kidney Disease Stage 3, Anemia, Chronic Kidney Disease Stage 4, Chronic Kidney Disease Stage 5
- Trial name
- DREAM-ND (NCT04012957)
- Testing
- Desidustat Oral Tablet, Darbepoetin Alfa
- Where
- 32 sites in India
- Volunteers
- 588 people
- Sponsor
- Zydus Lifesciences Limited
Chronic Kidney Disease, Predialysis
Educational Program on Dietary Adherence and Nutritional Knowledge in Chronic Kidney Disease Patients (EPAK)
A fundamental strategy to improve adherence to nutritional treatment in patients with chronic kidney disease is the implementation of educational programs.
- Conditions
- Chronic Kidney Disease, Predialysis, Peritoneal Dialysis, Hemodialysis
- Trial name
- EPAK (NCT06351007)
- Testing
- Nutritional education and psychological intervention, Standard care
- Where
- Mexico
- Volunteers
- 63 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Kidney Failure, Chronic
Metabolic and Inflammatory Responses to Hemodialysis and the Effect of a Meal
The objective of this study is to characterize the hormonal and inflammatory responses to hemodialysis, and to determine the effect of a meal versus fast on the metabolic changes in the post-dialytic phase.
- Trial name
- NCT01446302
- Testing
- Double meal
- Where
- 2 sites in Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Dialysis; Complications, COVID-19
Immune Response Following COVID-19 in Hemodialysis Patients
Patients with chronic kidney disease (CKD), particularly those undergoing hemodialysis (HD), are at high risk of a severe form of COVID-19.
- Conditions
- Dialysis; Complications, COVID-19, Cytokine Storm
- Trial name
- IMMUNOVIDIAL (NCT05307601)
- Where
- France
- Volunteers
- 21 people
- Sponsor
- AURA Paris
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