Clinical trials: Complication of Dialysis
Chronic Kidney Disease
Comparison of Effectiveness and Safety of Three Lock Solutions for Long-Term Central Venous Catheter for Hemodialysis
Background: Poor flow (PF) and catheter-related blood stream infections (CRBSI) are highly prevalent among CKD 5D patients with long-term central venous catheters.
- Trial name
- CLOCK (NCT02618317)
- Testing
- Heparin Lock Solution, Trissodium Citrate 30%, Minocycline-EDTA 30 mg/ml - 3 mg/ml
- Where
- Brazil
- Volunteers
- 75 people
- Sponsor
- University of Sao Paulo
Congestive Heart Failure, Cardiac Transplantation
Natrecor (Nesiritide) in Transplant-Eligible Management of Congestive Heart Failure-TMAC
The purposes of this study in United Network for Organ Sharing (UNOS) Status 1B (or country equivalent) cardiac transplant candidates are to assess the safety and efficacy of Natrecor (nesiritide).
- Conditions
- Congestive Heart Failure, Cardiac Transplantation, Renal Insufficiency, Renal Failure
- Trial name
- NCT00338455
- Testing
- Natrecor (nesiritide)+Standard Care+dobutamine or milrinone
- Where
- 14 sites in United States
- Volunteers
- 16 people
- Sponsor
- Scios, Inc.
Chronic Kidney Disease, Not on Dialysis
Safety and Tolerability Study of MCI-196
The objective of this study is to assess the safety and tolerability of colestilan (MCI-196) in paediatric subjects (aged 2 years to <18 years) with CKD stages 3b to 5, diagnosed with hyperphosphataemia, who are not on dialysis.
- Conditions
- Chronic Kidney Disease, Not on Dialysis, Hyperphosphatemia, Paediatric
- Trial name
- NCT01818687
- Testing
- colestilan
- Where
- United Kingdom
- Volunteers
- 4 people
- Sponsor
- Tanabe Pharma Corporation
Renal Insufficiency, Chronic
Effects by Omission of Bandage Over Exit Site
Peritoneal dialysis, known as p- dialysis (PD), is a dialysis form in which the blood is purified by using the body's peritoneum. PD dependents on good access to peritoneum.
- Trial name
- EXIT (NCT02102425)
- Testing
- Patients with or without bandage over exit site
- Where
- Denmark
- Volunteers
- 35 people
- Sponsor
- Edith Mark
Acute Kidney Injury
Pharmacokinetics of Vancomycin in the ICU in Renal Replacement Therapy
This study is an observational analysis that monitors the effect of different dialysis methods on vancomycin levels when patients are critically ill.
- Trial name
- NCT00848809
- Testing
- Blood sample
- Where
- United States
- Sponsor
- Avera McKennan Hospital & University Health Center
Acute Renal Failure
Assessing the Impact of Two Methods of Continuous Veno-venous Hemodiafiltration on Time Nursing Work in Intensive Care
The prevalence of acute renal failure in intensive care is estimated at between 5 and 20% depending on diagnostic criteria retained. And half of patients require the use of hemodialysis.
- Trial name
- NCT00993733
- Testing
- Continuous veno-venous haemodiafiltration
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
End-Stage Kidney Disease
Effect of Dialysis-specific Therapeutic Diet on Biochemical Parameters in Dialysis Patients
In patients with kidney failure, disturbances in bone turnover, mineral metabolism, vascular calcification, uremia, inflammation, immunity, metabolomics, nutrition, and gut microbial metabolites are frequent.
- Trial name
- NCT06377293
- Testing
- Dialysis-specific therapeutic diet
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Far Eastern Memorial Hospital
End Stage Renal Disease (ESRD), Peritoneal Dialysis Complication
The Effect of Exercise on Low Back Pain in Peritoneal Dialysis Patients
The goal of this randomized controlled trial is to find out if exercise can help reduce low back pain and improve quality of life in people receiving peritoneal dialysis (PD).
- Trial name
- NCT07000006
- Testing
- Home-based Core Stability Exercise
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- Pardis Specialized Wellness Institute
End Stage Renal Disease
Fluid Overload in Peritoneal Dialysis
The objective of this study is to determine the effectiveness of treating peritoneal dialysis (PD) patients with fluid overload by a structured nurse-lead intervention protocol.
- Trial name
- NCT02557347
- Testing
- Aggressive fluid management
- Where
- Hong Kong
- Volunteers
- 102 people
- Sponsor
- Chinese University of Hong Kong
Chronic Renal Failure
A Multicenter, Randomized, Open-labeled, Cross-over, Active-controlled, Phase IV Clinical Trial to Evaluate the Preference of Formulation and the Efficacy and Safety of Renamezin and Kremezin in Pre-dialysis Patients With Chronic Renal Failure
A Multicenter, Randomized, Open-labeled, Cross-over, Active-controlled, Phase IV Clinical Trial to Evaluate the Preference of Formulation and the Efficacy and Safety of Renamezin and Kremezin in Pre-dialysis Patients With Chronic…
- Trial name
- NCT02681952
- Testing
- Renamezin capsule, Kremezin granule
- Where
- South Korea
- Volunteers
- 153 people
- Sponsor
- Daewon Pharmaceutical Co., Ltd.
Complication of Dialysis, Chronic Kidney Disease
Efficacy of Beta-Hydroxy-Beta-Methylbutyrate (HMB) Supplementation in Hemodialysis Patients
The purpose of this study is to examine the effect of 6 months of daily beta-hydroxy beta-methylbutyrate (HMB) supplementation on the physical function and the health of bones, arteries and heart in hemodialysis patients.
- Conditions
- Complication of Dialysis, Chronic Kidney Disease, Muscle Loss, End Stage Renal Disease
- Trial name
- NCT01837238
- Testing
- HMB
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- University of Illinois at Urbana-Champaign
End Stage Renal Disease, ESRD
Safety and Efficacy Assessments of NeoKidney® in ESRD Patients Treated With Short Daily Hemodialysis
The goal of this clinical investigation is to asses the safety and efficacy a new sorbent-based hemodialysis device, NeoKidney® in ESRD patients treated with short daily hemodialysis.
- Trial name
- FIH Caen (NCT06024135)
- Testing
- NeoKidney
- Where
- France
- Volunteers
- 5 people
- Sponsor
- Nextkidney S.A.
End Stage Renal Disease, Continuous Ambulatory Peritoneal Dialysis
Open-label, Randomized Trial to Determine the Effect of Icodextrin Versus Dextrose (Dianeal 2.5%) in HOMA IR
Phase IV post-marketing study to evaluate the effect of Extraneal on the HOMA index in non-diabetic CAPD patients over the long-dwell exchange.
- Trial name
- ECOS (NCT01093547)
- Testing
- Blood samples, Measure of peritoneal ultrafiltrates
- Where
- Colombia
- Sponsor
- Vantive Health LLC
Chronic Kidney Disease
Pharmacokinetic/Pharmacodynamic Parameters of NNG-DEPO (Stimus) With Aranesp® (Amgen) in Treatment of Anemia in CKD Patients on Dialysis
This is a double-blind, randomized, active-control study with 2-study arms-darbepoetin alfa biosimilar and Aranesp, noninferiority trial design in dialysis patients.
- Trial name
- CKD (NCT05636891)
- Testing
- Stimus
- Where
- Vietnam
- Volunteers
- 43 people
- Sponsor
- Nanogen Pharmaceutical Biotechnology Joint Stock Company
Complication of Hemodialysis, Cardiovascular Diseases
Sodium Thiosulfate Treatment of Vascular Calcification in ESRD
Cardiovascular disease is the major cause of death in the hemodialysis population and calcification of the major arteries (coronary, aorta, and carotid) are a play a central role in this process.
- Trial name
- NCT00568399
- Testing
- sodium thiosulfate
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Washington University School of Medicine
Other Complication of Vascular Dialysis Catheter
Effect of the TEGO Connector in Preventing Tunneled Cuffed Hemodialysis Catheters From Dysfunction and/or Bacteremia
The aim of the trial was to assess whether use of the TEGO connector was able to reduce the incidence of a composite endpoint of TCC-related dysfunction (TCC-D)or TCC-related bacteremia (TCC-B) in chronic hemodialysis (HD)…
- Trial name
- NCT01689753
- Testing
- TEGO connector®, Trisodium citrate
- Where
- Belgium
- Volunteers
- 66 people
- Sponsor
- Erasme University Hospital
Renal Dialysis, Hemodiafiltration
Effect of Intradialytic Exercise on Left Ventricular Diastolic Function in Hemodialysis Patients
Introduction: Cardiovascular disease is the leading cause of morbidity and mortality in patients undergoing hemodialysis, largely due to structural cardiac changes associated with left ventricular diastolic dysfunction.
- Conditions
- Renal Dialysis, Hemodiafiltration, Diastolic Dysfunction, Kidney Failure
- Trial name
- EXE-HDF (NCT06584734)
- Testing
- Not exercise, Exercise during hemodiafiltration session
- Where
- Mexico
- Volunteers
- 30 people
- Sponsor
- Instituto Nacional de Cardiologia Ignacio Chavez
Uremia
Effects of Convective Therapies in Dialysis Patients
Convective therapies have been proposed for improving chronic dialysis patient outcomes, including intradialytic symptomatic hypotension.
- Trial name
- ECTDP (NCT01583309)
- Testing
- online pre-dilution hemofiltration, online pre-dilution hemodiafiltration
- Where
- 27 sites in Italy
- Volunteers
- 146 people
- Sponsor
- A. Manzoni Hospital
Peritoneal Dialysis Associated Peritonitis
Bacteria Endotoxin in Peritoneal Dialysis Effluent as a Predictor of Relapsing, Recurrent, and Repeat Peritonitis
Peritoneal dialysis (PD) is the first-line treatment of end stage renal disease (ESRD) in Hong Kong. Despite the advances in antibiotic therapy and connecting system, recurrent peritonitis remains the major cause of peritoneal…
- Trial name
- NCT01817309
- Testing
- endotoxin assay in peritoneal dialysis effluent
- Where
- Hong Kong
- Volunteers
- 325 people
- Sponsor
- Chinese University of Hong Kong
End-Stage Renal Disease, Renal Dialysis
Effects of Horticultural Therapy on Acute Stress and Salivary Cortisol Levels in Hemodialysis Patients
The purpose of this study is to evaluate the acute psychological and physiological effects of a single-session structured horticultural therapy program on patients undergoing routine hemodialysis.
- Conditions
- End-Stage Renal Disease, Renal Dialysis, Acute Stress
- Trial name
- NCT07845214
- Testing
- Horticultural Therapy
- Volunteers
- 80 people
- Sponsor
- Ataturk University
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