Clinical trials: Complication of Hemodialysis
End Stage Renal Disease, Cardiovascular Disease
Pomegranate and Hemodialysis Pilot Trial
In this study, the investigators will administer pomegranate juice or fruit extract as a targeted antioxidant therapy to hemodialysis patients.
- Conditions
- End Stage Renal Disease, Cardiovascular Disease, Inflammation
- Trial name
- POM Pilot (NCT01562340)
- Testing
- Pomegranate juice, Pomegranate fruit extract
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Washington
Hemodialysis Complication
Effect of Pentoxifylline on Anemia in Hemodialysis Patients
The primary goal of this clinical trial is to evaluate the promoting effect of pentoxifylline on anemia correction in hemodialysis patients, and involvement of the hypoxia-inducible factor-2 alpha.
- Trial name
- NCT05708248
- Testing
- pentoxifylline
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Alexandria University
Anemia, Chronic Renal Failure
Safety & Efficacy of Peginesatide for Treatment of Anemia in Participants on Dialysis Not Receiving an ESA
The purpose of this study is to evaluate the safety and efficacy of peginesatide for the treatment of anemia in participants with chronic kidney disease who are on dialysis and are not taking any treatment to increase their red…
- Conditions
- Anemia, Chronic Renal Failure, Chronic Kidney Disease
- Trial name
- NCT00680043
- Testing
- peginesatide, Epoetin Alfa
- Where
- 11 sites in Russia
- Volunteers
- 114 people
- Sponsor
- Affymax
ESRD
Experience of Patients Starting Hemodialysis
Patients starting dialysis have significant and often daunting changes to their lifestyle, and investigators have only little information from the patient perspective on patient experiences during dialysis initiation.
- Trial name
- NCT04988568
- Testing
- None. This is a qualitative interview study.
- Where
- 17 sites in United States
- Volunteers
- 20 people
- Sponsor
- Satellite Healthcare
Secondary Hyperparathyroidism, Chronic Kidney Disease
A Trial of Etelcalcetide in Pediatric Participants With Secondary Hyperparathyroidism and Chronic Kidney Disease on Hemodialysis
This is a phase 3 trial of etelcalcetide in pediatric participants with secondary hyperparathyroidism (SHPT) and chronic kidney disease (CKD) on hemodialysis.
- Trial name
- NCT03633708
- Testing
- Etelcalcetide, Standard of Care
- Where
- 43 sites in United States, Argentina and 8 more
- Volunteers
- 56 people
- Sponsor
- Amgen
Chronic Kidney Disease (Stages 4 and 5), Hemodialysis
Intradialytic Rehabilitation and Functional Independence in Hemodialysis Patients
This study evaluated whether a rehabilitation program performed during hemodialysis sessions could improve daily functioning and mobility in adults receiving maintenance hemodialysis.
- Trial name
- NCT07442240
- Testing
- Dynamic Lumbar Stabilization Exercises, Respiratory Muscle Training
- Volunteers
- 56 people
- Sponsor
- Bandırma Onyedi Eylül University
Renal Dialysis, Kidney Failure, Chronic
Safety and Pharmacokinetics of MK-2060 in Older Participants With End-Stage Renal Disease on Hemodialysis (MK-2060-004)
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of MK-2060 after intravenous (IV) administration of single and multiple doses in older adult participants with…
- Trial name
- NCT03873038
- Testing
- MK-2060
- Where
- 3 sites in United States
- Volunteers
- 38 people
- Sponsor
- Merck Sharp & Dohme LLC
End Stage Renal Disease
Comparison of Two Exercise Programmes in Patients Undergoing Hemodialysis
Although exercise training of haemodialysis patients is associated with generally positive outcomes few haemodialysis units routinely offer intradialytic exercise therapy.
- Trial name
- NCT02832440
- Testing
- Exercise programmes
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Cardenal Herrera University
End-stage Renal Disease
Comparison Study of Daily Ultrafiltration and Twice-weekly Hemodialysis
In this study, the researchers want to find out how patients who have ultrafiltration (removal of excess fluid) 6 times a week and twice-weekly dialysis (removal of excess fluid and waste products) do in terms of their blood…
- Trial name
- NCT00825318
- Testing
- Ultrafiltration
- Where
- 3 sites in United States
- Volunteers
- 13 people
- Sponsor
- Renal Research Institute
Chronic Kidney Diseases, Hyperphosphatemia
A Study to Evaluate Safety and Efficacy of AP-306 in Hyperphosphatemia Patients
The goal of this clinical trial is to learn about the following questions in the patients receiving maintenance hemodialysis with elevated blood phosphorus: How much effect AP-306 has assessed by blood phosphorus lowering; How…
- Trial name
- NCT05764590
- Testing
- AP-306, Sevelamer Carbonate
- Where
- China
- Volunteers
- 55 people
- Sponsor
- Alebund Pharmaceuticals
Oxidative Stress Response, Hemodialysis
Effects of L-carnitine and Coenzyme Q10 Supplementation on Oxidative Stress in Tunisian Hemodialysis Patients.
The goal of this clinical trial was to learn if supplementation with L-carnitine or Coenzyme Q10 improves effectively the oxidative stress markers in adult patients undergoing chronic hemodialysis.
- Conditions
- Oxidative Stress Response, Hemodialysis, End Stage Kidney Disease (ESRD)
- Trial name
- L-car-Q10 (NCT07303088)
- Testing
- Oral administration of L-carnitine 1000 Mg, Oral administration of Coenzyme Q10 300Mg
- Where
- Tunisia
- Volunteers
- 52 people
- Sponsor
- University of Sfax
Chronic Kidney Disease
Acute Effects of Cinacalcet on Arterial Stiffness and Ventricular Function in Hemodialysis Patients
The primary objective is to determine whether reduction of serum calcium concentration by cinacalcet leads to reduction of mean blood pressure adjusted c-fPWV.
- Trial name
- ECIRA (NCT01250405)
- Testing
- Cinacalcet
- Where
- Canada
- Volunteers
- 23 people
- Sponsor
- Laval University
Renal Insufficiency, Hemodialysis
A Study on the Effect of Kidney Disease on a Diabetes Medication (0431-008)
A study to evaluate the effect of kidney disease, from mild to severe disease, on a diabetes medication
- Trial name
- NCT00418366
- Testing
- MK0431, sitagliptin phosphate / Duration of Treatment : 1 Days
- Volunteers
- 24 people
- Sponsor
- Merck Sharp & Dohme LLC
Renal Insufficiency, Chronic
To Investigate Pharmacokinetics (Absorption, Distribution, Elimination), Safety and Tolerability of a Single Oral Dose of 75 mg Molidustat Tablet in Male and Female Subjects Requiring Hemo- or Peritoneal Dialysis Compared to Healthy Subjects
The study investigates the pharmacokinetics (absorption, distribution, elimination) of molidustat after intake of a single 75 mg tablet in subjects with renal impairment requiring hemo- or peritoneal dialysis compared to age-and…
- Trial name
- NCT02312973
- Testing
- Molidustat(BAY85-3934)
- Where
- 2 sites in Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bayer
ESRD (End Stage Renal Disease)
Research and Validation of a Big Data-Driven Intelligent Decision-Making System for Hemodialysis
Objectives and Scope:This observational study aims to leverage real-world data from Huashan Hospital to develop an AI-driven intelligent decision-making system for assessing dialysis adequacy in maintenance hemodialysis (MHD)…
- Trial name
- NCT07466329
- Where
- China
- Volunteers
- 778 people
- Sponsor
- Huashan Hospital
Kidney Failure, Chronic
Efficacy and Safety of Lanthanum Carbonate and Sevelamer Hydrochloride in Patients Receiving Haemodialysis for End Stage Renal Disease
The purpose of this study is to assess phosphate reduction and control in patients with End Stage Renal Disease treated with either lanthanum carbonate or sevelamer hydrochloride
- Trial name
- NCT00151918
- Testing
- Lanthanum carbonate
- Volunteers
- 48 people
- Sponsor
- Shire
Hemodialysis Complication, Hemodialysis-Induced Symptom
Evaluation of Curcumin's Effect on Inflammation in Hemodialysis Patients
Programmed ingestion of turmeric has no adverse effects and reduces plasma level of hs-CRP, IL-6 and TNF-α accompanying with increases albumin levels in hemodialysis patients.
- Trial name
- NCT03144882
- Testing
- Curcumin Pill
- Volunteers
- 71 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Chronic Kidney Disease
Test of the Nipro ELISIO H Dialyzer in Different Dialysis Treatment Procedures
A current trend in dialysis membrane engineering is to maximize the permeability for larger low-molecular weight proteins while retaining albumin. Protein-leaking dialysis membranes do not meet these requirements.
- Trial name
- NCT00735059
- Testing
- treatment with the dialyzer ELISIO 170H, treatment with the dialyzer PES-170DS
- Where
- Belgium
- Volunteers
- 14 people
- Sponsor
- EXcorLab GmbH
Hemodialysis Patients
Impact on the Proteolysis of Obesity in Dialysis
The objective of this study is to determine whether obesity has a protective effect on muscle proteolysis in hemodialysis patients submitted to a short starvation.
- Trial name
- IPOD (NCT01114789)
- Testing
- Proteolysis
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
End Stage Renal Disease, Exercise, Compulsive
Intradialytic High-Intensity Interval Training in Hemodialysis Patients
Chronic Kidney Disease (CKD) is defined as a chronic, progressive degeneration state in the regulation of the fluid-electrolyte balance of the kidney and metabolic-endocrine functions as a result of the glomerular filtration rate…
- Trial name
- NCT05257668
- Testing
- High Intensity Interval Exercise Training, Moderate Intensity Exercise Training
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Yasemin ASLAN KELEŞ
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