Clinical trials: Complication of Hemodialysis
End-stage Renal Disease
Propaten Randomized Investigation on Cost-benefit and Efficacy
The purpose for this study is to evaluate the patency and outcomes of conventional and heparin anticoagulant bonded arteriovenous grafts in patients with end stage renal disease.
- Trial name
- PRICE (NCT01601873)
- Testing
- PROPATEN, Standard Graft
- Where
- 5 sites in United States
- Volunteers
- 103 people
- Sponsor
- The University of Texas Health Science Center, Houston
Potassium Imbalance, Cardiac Arrhythmia
The Effect of Potassium Lowering Drugs on Cardiac Electrical Stability in Hemodialysis Patients (ART Study)
This study is a multicenter, prospective and randomized controlled study. The experiment includes a 1-week screening period (1 week before dialysis) and a 7-week treatment period (1-4 weeks of dose drip period and 5-7 weeks of…
- Conditions
- Potassium Imbalance, Cardiac Arrhythmia, Dialysis; Complications
- Trial name
- NCT06242041
- Testing
- sodium zirconium cyclic silicate
- Where
- China
- Volunteers
- 61 people
- Sponsor
- Peking University First Hospital
Kidney Failure, Chronic, Renal Dialysis
Evaluating the Safety and Effectiveness of the InnAVasc Graft for Dialysis Access in Patients With Kidney Failure
The CSP-1001 study will evaluate the safety and effectiveness of the InnAVasc arteriovenous graft (AVG) when implanted in and used for hemodialysis in participants suffering from end stage renal failure (ESRD).
- Trial name
- NCT03645681
- Testing
- InnAVasc arteriovenous graft surgical implant
- Where
- 7 sites in United States
- Volunteers
- 26 people
- Sponsor
- W.L.Gore & Associates
Restless Legs Syndrome, End Stage Renal Disease
Exercise Training in Dialysis Patients With Restless Legs Syndrome (RLS)
Uremic etiology Restless legs syndrome (RLS) has been associated with poorer quality of life (QoL) compared to RLS-free counterparts mainly due to sleep deprivation factors.
- Conditions
- Restless Legs Syndrome, End Stage Renal Disease, Hemodialysis, Muscle Cachexia
- Trial name
- HDRLS (NCT00942253)
- Testing
- Dopamine Agonist and Exercise
- Where
- Greece
- Volunteers
- 46 people
- Sponsor
- University of Thessaly
Chronic Kidney Diseases, Hemolysis
Changes of Ocular Structures After Hemodialysis in Patients With Chronic Kidney Diseases
To evaluate the effect of hemodialysis on various ophthalmologic parameters in patients with end-stage kidney disease (ESRD).
- Trial name
- NCT03434145
- Testing
- ophthalmologic exams
- Volunteers
- 40 people
- Sponsor
- Hanyang University
IgAN - IgA Nephropathy
Assessing the Global Burden of IgA Nephropathy (IgAN) in Patients Receiving Hemodialysis: A Real-World Study Using DOPPS Data
This study leverages the global Dialysis Outcomes and Practice Patterns Study (DOPPS) database to generate real-world evidence on the burden of IgAN in patients who progress to kidney failure and require maintenance hemodialysis…
- Trial name
- NCT07607002
- Volunteers
- 70,000 people
- Sponsor
- Arbor Research Collaborative for Health
End-Stage Renal Disease, Secondary Hyperparathyroidism
A Study to Evaluate the Safety of Paricalcitol Capsules in Pediatric Subjects Ages 10 to 16 With Stage 5 Chronic Kidney Disease Receiving Peritoneal Dialysis or Hemodialysis
The objective is to evaluate the safety of paricalcitol capsules in pediatric subjects, ages 10 to 16 years old, with Stage 5 chronic kidney disease (kidney failure) receiving peritoneal dialysis or hemodialysis and being treated…
- Trial name
- NCT01382212
- Testing
- paricalcitol
- Volunteers
- 13 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Chronic Kidney Diseases, Inflammation
Effects of Microencapsulated Propolis and Turmeric in Patients With Chronic Kidney Disease
Oxidative stress and inflammation are correlated with Chronic Kidney Disease (CKD), in a way that they bring several harms to patients, including an increased risk of cardiovascular disease and mortality.
- Trial name
- NCT05183737
- Testing
- Microcapsules with turmeric and propolis
- Where
- Brazil
- Volunteers
- 34 people
- Sponsor
- Universidade Federal Fluminense
Kidney Diseases
Cardio Protective Effect of SGL2I in Hemodialysis Patients and Its Impact on Patient Quality of Life
If this study has a cardio protective effect it will affect the mortality and morbidity of advanced CKD patients and improve their quality of life
- Trial name
- NCT06759077
- Testing
- Dapagliflozin (DAPA)
- Where
- Egypt
- Volunteers
- 126 people
- Sponsor
- Al-Azhar University
Renal Impairment, End-stage Renal Disease
An Efficacy, Safety, Tolerability and Pharmacokinetics Study of 12 Weeks Treatment With Simeprevir and Daclatasvir in Participants With Chronic Hepatitis C Virus Genotype 1b or 4 Infection and Either Severe Renal Impairment or End-stage Renal Disease on Hemodialysis.
The purpose of this study is to evaluate the percentage of participants with sustained virologic response 12 weeks after the actual end of study treatment (SVR12)
- Trial name
- NCT02397395
- Testing
- Simeprevir (SMV) 150 mg, Daclatasvir (DCV) 60 mg
- Where
- 6 sites in France, Spain
- Sponsor
- Janssen R&D Ireland
Chronic Kidney Disease
Pharmacokinetic Comparison of Vitamin's D2 and D3 in Stage 5 Chronic Kidney Disease Patients on Chronic Hemodialysis
The purpose of this study is to compare the pharmacokinetic 25(OH)D and 1,25(OH)2D responses to a single oral dose of vitamin D2 or vitamin D3 in a group of Stage 5-Chronic Kidney Disease subjects requiring chronic hemodialysis.
- Trial name
- NCT01675557
- Testing
- Vitamin D3, Vitamin D2
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Creighton University
Hyperphosphatemia, Chronic Kidney Disease
A Phase 2 Study of ASP1585 in Chronic Kidney Disease Patients With Hyperphosphatemia on Hemodialysis
To evaluate the superiority to placebo, dose-responsibility and safety.
- Trial name
- NCT00505037
- Testing
- ASP1585, Sevelamer hydrochloride
- Where
- 6 sites in Japan
- Volunteers
- 156 people
- Sponsor
- Astellas Pharma Inc
End Stage Renal Disease
Triferic Pediatric Pharmacokinetic Protocol
The main purpose is to determine the pharmacokinetics (PK) of Triferic iron administered intravenously in pediatric patients with chronic kidney disease on chronic hemodialysis (CKD-5HD).
- Trial name
- NCT02595437
- Testing
- Triferic
- Where
- 9 sites in United States
- Volunteers
- 22 people
- Sponsor
- Rockwell Medical Technologies, Inc.
Kidney Failure, Chronic
Effects of Intradialytic Exercise as Assessed by Bioimpedance Analysis and Blood Volume Monitoring
The purpose of this study is to examine the impact of exercise during dialysis using objective measures of fluid status determination, specifically bioimpedance analysis (BIA) and blood volume monitoring (BVM).
- Trial name
- NCT01273753
- Testing
- Intradialytic exercise
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Michigan
End-Stage Renal Disease
Safety Study to Evaluate Daptomycin in Non-infected Adults Who Are Either on Hemodialysis or Continuous Ambulatory Peritoneal Dialysis (MK-3009-021)
This study is to examine the safety of daptomycin in patients with End Stage Renal Disease.
- Trial name
- NCT00490737
- Testing
- daptomycin
- Volunteers
- 12 people
- Sponsor
- Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
End-stage Renal Disease, Left Ventricular Hypertrophy
In-Centre Nocturnal Hemodialysis (INHD): A Long-Term Follow-Up Study
Background: In 2010, approximately 39000 Canadians had end-stage renal disease (ESRD), and the prevalence rate of dialysis has increased by 189% over the past 2 decades.
- Trial name
- INHD (NCT02684773)
- Testing
- Conventional Hemodialysis, In-centre Nocturnal Hemodialysis
- Where
- 2 sites in Canada
- Volunteers
- 67 people
- Sponsor
- Unity Health Toronto
Cardio-renal Syndrome
Ultrafiltration Versus Medical Therapies in the Management of the Cardio Renal Syndrome
Type 2 cardio renal syndrome is defined by the occurrence or the exacerbation of a kidney failure induced by a chronic heart failure.
- Trial name
- UF-CARE (NCT02846337)
- Testing
- ULTRAFILTRATION, ENHANCED MEDICAL TREATMENT
- Where
- France
- Volunteers
- 108 people
- Sponsor
- Hospices Civils de Lyon
Chronic Kidney Disease, Stage 5
Head to Head Study Against Sevelamer Hydrochloride
To compare the efficacy of Fosrenol (Lanthanum carbonate) and sevelamer hydrochloride in the reduction of serum phosphorus levels from baseline.
- Trial name
- NCT00441545
- Testing
- Fosrenol (Lanthanum Carbonate), Sevelamer hydrochloride
- Where
- 44 sites in United States, Germany and 2 more
- Volunteers
- 182 people
- Sponsor
- Shire
Secondary Hyperparathyroidism, End Stage Renal Disease
A Study of an Investigational Medication for the Treatment of Secondary Hyperparathyroidism in Patients on Dialysis
This 6 month study will assess an investigational medication for patients on dialysis with secondary hyperparathyroidism. The study will look at the effects on parathyroid hormone, calcium and phosphorus levels.
- Trial name
- NCT00042653
- Testing
- AMG 073
- Volunteers
- 380 people
- Sponsor
- Amgen
Carcinoma, Renal Cell
Study of Orellanine in Metastatic Clear-Cell or Papillary Renal Cell Carcinoma
A phase I/II, open-label, study to determine the safety and preliminary efficacy of orellanine in patients with metastatic clear-cell or papillary renal carcinoma who have failed standard-of-care therapy.
- Trial name
- NCT05287945
- Testing
- Orellanine
- Where
- 10 sites in United States, France and 3 more
- Volunteers
- 75 people
- Sponsor
- Oncorena AB
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