Clinical trials: Complication of Hemodialysis
Acute Kidney Injury
Standard vs. Accelerated Initiation of RRT in Acute Kidney Injury (STARRT-AKI: Principal Trial)
The objectives of this trial are to determine whether, in critically ill patients with severe acute kidney injury (AKI), randomization to accelerated initiation of renal replacement therapy (RRT), compared to standard initiation…
- Trial name
- NCT02568722
- Testing
- Standard RRT initiation, Accelerated RRT initiation
- Where
- 105 sites in United States, Australia and 13 more
- Volunteers
- 3,019 people
- Sponsor
- Unity Health Toronto
End-Stage Renal Disease
Effect of Different Hemodialysis Modality on Adiponectin,Vascular Function and Clinical Prognosis
Adiponectin, an adipose tissue derived protein, with anti-inflammatory properties that is secreted from adipose tissue, is associated with insulin resistance.
- Trial name
- NCT00155363
- Testing
- conventional artificial kidney (AK) vs. high flux AK
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital
End Stage Renal Disease
Efficacy Study of Zinc Supplementation on Anemia, Oxidative Stress and Inflammation in Hemodialysis Patients
The purpose of the study is to evaluate the effect of Zinc supplementation on health status of hemodialysis patients through measurement of the following before and after Zinc administration: Inflammatory markers, Oxidative…
- Trial name
- NCT02335593
- Testing
- Zinc Sulphate, Corn Starch filled Hard Gel Capsules, Epoetin alfa 2000-4000 IU solution for injection
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Ain Shams University
Chronic Kidney Disease Requiring Hemodialysis, Chronic Kidney Disease
Serum circ_DLGAP4, lncRNA KCNQ1OT1, and Their Targets by Erythropoietin Resistance in Chronic Kidney Disease
Non-coding RNAs have evolved as biomarkers and as phased and specific therapeutic targets for chronic kidney disease (CKD). However, their clinical significance in CKD patients is largely unexplored.
- Trial name
- NCT07037953
- Where
- Egypt
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
End Stage Renal Disease
Evaluation of STARgraft AV for Hemodialysis Access
This study is a First-in-Human, single site, prospective, randomized, controlled evaluation of the safety and effectiveness of the Healionics STARgraft AV hemodialysis access graft.
- Trial name
- NCT03916731
- Testing
- STARgraft AV, ePTFE AV graft (control)
- Where
- Paraguay
- Volunteers
- 55 people
- Sponsor
- Healionics Corporation
Chronic Renal Failure, Chronic Kidney Disease
Safety & Efficacy of Peginesatide for Maintenance Treatment of Anemia in Participants With Chronic Kidney Disease on Hemodialysis
The purpose of the study was to evaluate the safety and efficacy of peginesatide in the maintenance treatment of anemia in participants on dialysis.
- Conditions
- Chronic Renal Failure, Chronic Kidney Disease, Anemia
- Trial name
- EMERALD 1 (NCT00597753)
- Testing
- peginesatide, Epoetin Alfa
- Where
- 89 sites in United States
- Volunteers
- 803 people
- Sponsor
- Affymax
Secondary Hyperparathyroidism, End Stage Renal Disease
A Study of an Investigational Medication for the Treatment of Secondary Hyperparathyroidism in Patients on Dialysis
This 6 month study will assess an investigational medication for patients on dialysis with secondary hyperparathyroidism. The study will look at the effects on parathyroid hormone, calcium and phosphorus levels.
- Trial name
- NCT00042653
- Testing
- AMG 073
- Volunteers
- 380 people
- Sponsor
- Amgen
End-Stage Renal Disease
Decellularized Femoral Artery Allograft (Nexeon AVX) Prospective Registry
Post market registry to assess the safety and efficacy of a novel decellularized human femoral artery allograft (Nexeon AVX Decellularized Femoral Artery,
- Trial name
- NCT05880537
- Testing
- Nexeon Arterial Venous Allograft
- Where
- 4 sites in United States
- Volunteers
- 100 people
- Sponsor
- LifeNet Health
Chronic Kidney Disease
The Effects of Resveratrol on the Complications of Patients With Hemodialysis
Participants'll include 140 adult patients with CKD and receiving hemodialysis in our hospital, and divided them into 2 groups. Control group will receive placebo medication therapy; resveratrol group will receive oral…
- Trial name
- NCT03352895
- Testing
- resveratrol
- Where
- Taiwan
- Volunteers
- 36 people
- Sponsor
- Dalin Tzu Chi General Hospital
Chronic Renal Failure Requiring Hemodialysis
A Phase 3, Long-Term Safety Study of Subcutaneous Epoetin Hospira in Patients With Chronic Renal Failure Requiring Hemodialysis and Receiving Epoetin Maintenance Treatment. AiME -Anemia Management With Epoetin
To determine the long term safety in treatment-emergent adverse events (TEAEs) of SC administration of Epoetin Hospira for maintenance of target hemoglobin (Hgb) levels in patients treated for anemia associated with chronic renal…
- Trial name
- AiME - 04 (NCT01628120)
- Testing
- Epoetin Hospira
- Where
- 115 sites in United States
- Volunteers
- 170 people
- Sponsor
- Pfizer
Renal Insufficiency, Chronic
Interest of the Peak of Reticulocytes in Chronic Hemodialysis Patients Treated by Mircera Hemodialysis Population
Patients under hemodialysis treatment are mostly treated by erythropoietin (EPO) through erythropoiesis stimulating agents (ESA).
- Trial name
- RETICERA (NCT02832323)
- Testing
- Reticera
- Where
- 9 sites in France
- Volunteers
- 94 people
- Sponsor
- University Hospital, Brest
Kidney Failure
Mobilising Lower Limb Fluid for Hemodynamic Stability in Haemodialysis
Cardiovascular disease is the leading cause of death of dialysis patients and poor fluid management is associated with the increased risk.
- Trial name
- NCT02450474
- Testing
- Intermittent pneumatic compression device, Neuromuscular electrical stimulation
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
Hemodialysis Complication
Twice Against Thrice-weekly Hemodialysis
Hemodialysis is the most worldwide prescribed renal replacement therapy for patients with end-stage renal disease. The frequency of sessions per week remains a debatable issue.
- Trial name
- TATH (NCT03415776)
- Testing
- Hemodialysis
- Where
- Lebanon
- Volunteers
- 208 people
- Sponsor
- Saint-Joseph University
Chronic Kidney Diseases, End Stage Renal Disease
Validity of Low Physical Activity Questionnaire (LoPAQ)
The goal of this observational study is to assess validity and reliability of Persian Version of Low Physical Activity Questionnaire.
- Conditions
- Chronic Kidney Diseases, End Stage Renal Disease, Hemodialysis Complication
- Trial name
- NCT05930964
- Where
- Iran
- Volunteers
- 100 people
- Sponsor
- Pardis Specialized Wellness Institute
Acute Kidney Injury, Continuous Renal Replacement Therapy
Continuous Veno-venous Hemodialysis and Continuous Veno-venous Hemodiafiltration on Urea Reduction Rate in Intensive Care Patient
In patients requiring renal replacement therapy (RRT) in the intensive care unit (ICU), continuous techniques are predominantly using due to better hemodynamic tolerance.
- Conditions
- Acute Kidney Injury, Continuous Renal Replacement Therapy, Intensive Care Unit
- Trial name
- CompEER (NCT06369064)
- Testing
- CVVHD Dialysis parameters, CVVHDF Dialysis parameters
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Chronic Kidney Disease Stage V, End-Stage Renal Disease
Autogenic Relaxation and Murottal Therapy in Hemodialysis Patients
This quasi-experimental study aims to evaluate the effect of combined autogenic relaxation and Surah Ar-Rahman murottal therapy on anxiety, sleep quality, and hemodynamic parameters in hemodialysis patients.
- Conditions
- Chronic Kidney Disease Stage V, End-Stage Renal Disease, Hemodialysis
- Trial name
- AR-MHD (NCT07412548)
- Testing
- Autogenic Relaxation and Surah Ar-Rahman Murottal Therapy, listening to dangdut music
- Where
- Indonesia
- Volunteers
- 76 people
- Sponsor
- Universitas Muhammadiyah Surakarta
Acute Kidney Injury, Hemodialysis
Role of Vascular Endothelial Markers in Predicting Renal Prognosis and Mortality in Patients Undergoing HD-AKI
The aim of this study was to evaluate the role of Activin A, Nostrin, and Angiopoetin-2 levels in predicting the prognosis of renal function and in-hospital and 6-month mortality in patients undergoing emergency hemodialysis…
- Trial name
- VEMhemodiAKI (NCT07637435)
- Testing
- Serum samples before hemodialysis.
- Where
- Turkey (Türkiye)
- Volunteers
- 170 people
- Sponsor
- Muğla Sıtkı Koçman University
Hemodialysis, End-stage Renal Disease
Mechanisms and Treatment of Intradialytic Hypertension - Sodium
The purpose of this study is to determine the role of dialysate exposure and fluid removal during hemodialysis in the pathophysiology of intradialytic hypertension.
- Conditions
- Hemodialysis, End-stage Renal Disease, Hypertension, Intradialytic Hypertension
- Trial name
- MATCH-Sodium (NCT01371890)
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Texas Southwestern Medical Center
Uremia, Arteriovenous Fistula
Stenosis of Arteria-Venous Fistula in Maintenance Hemodialysis Patients: Early Intervention Trial
The purpose of this study is to compare the effect of DSA guided percutaneous balloon dilatation, ultrasound guided percutaneous balloon dilatation and surgical repair in the treatment of Stenosis of Arteria-Venous Fistula in…
- Conditions
- Uremia, Arteriovenous Fistula, Stenosis
- Trial name
- SAVEIT (NCT02266238)
- Testing
- DSA guided percutaneous balloon dilatation, Ultrasound guided percutaneous balloon dilatation, Surgical reconstruction
- Where
- China
- Volunteers
- 450 people
- Sponsor
- Shanghai Changzheng Hospital
Uremia, Uremic Osteodystrophy
Multi-center Clinical Study on Hemoperfusion of KHA80
To evaluate the decreasing rate of blood IL-6, β2-MG and PTH in maintenance hemodialysis patients in the 52nd week compared with routine hemodialysis.
- Conditions
- Uremia, Uremic Osteodystrophy, Dialysis Related Complication
- Trial name
- NCT06233838
- Testing
- KHA80 hemoperfusion treatment
- Where
- China
- Volunteers
- 394 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
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