Clinical trials: Complication of Hemodialysis
Chronic Renal Failure, Sleep Disorder
Light Therapy on Sleep Quality in Dialysis Patients
Sleep disorders are common in dialysis patients. At present, the management of insomnia in patients with chronic renal failure is not significantly different from that of the general population, which focuses on the management of…
- Conditions
- Chronic Renal Failure, Sleep Disorder, Hemodialysis, Light Therapy
- Trial name
- LUMIDIAL (NCT04089397)
- Testing
- Light Therapy
- Where
- France
- Volunteers
- 33 people
- Sponsor
- Centre Hospitalier Annecy Genevois
Multiple Myeloma
Efficacy and Safety of Pomalidomide and Dexamethasone in RRMM Patients With Renal Insufficiency
The primary purpose of the study is to determine the safety and efficacy and to generate PK and biomarker data for the combination of Pomalidomide and low-dose Dexamethasone in patients with relapsed or refractory multiple…
- Trial name
- NCT02045017
- Testing
- Pomalidomide and Dexamethasone
- Where
- 22 sites in Austria, France and 6 more
- Volunteers
- 81 people
- Sponsor
- Celgene
Renal Failure
Hemodialysis and Wanting for Protein-rich Foods
A study conducted in the laboratory revealed the existence of a "window" during which patients with renal failure appreciate the protein-rich foods.
- Trial name
- NCT02221050
- Where
- France
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Burgundy
End Stage Renal Disease
Dehydr8 and Deactiv8
Managing fluid status is a complex but fundamental part of the clinical care of people receiving haemodialysis (HD). Day-to-day fluid management is usually based on the concept of 'target weight' - the weight used to determine…
- Trial name
- NCT03179072
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Portsmouth
Chronic Renal Insufficiency
Creation and Validation of a Questionnaire to Measure the Feelings of a Chronic Renal Insufficiency Person During His Hemodialysis
Chronic Hemodialysis is a treatment for kidney failure. It involves the construction of three treatment sessions per week extrarenal lasting 4 hours each.
- Trial name
- VecuHD (NCT02791828)
- Where
- France
- Volunteers
- 297 people
- Sponsor
- CHU de Reims
End-Stage Renal Disease
Study of Home-Embedded Palliative Care for Hemodialysis- (and Peritoneal-) Dependent End-Stage Renal Disease
Home palliative care needs are often under-recognized in patients with End-Stage Renal Disease (ESRD). This pilot study is designed to evaluate the effectiveness of referrals to home palliative care services in improving patient…
- Trial name
- SHEPHERD 2 (NCT06144281)
- Testing
- Nudge for PHPC NP Referral
- Where
- United States
- Volunteers
- 315 people
- Sponsor
- University of Pennsylvania
Supportive Care, Exercise Adaptations
Intradialytic Exercise and Cognitive Function
Exercise training may improve global and domain-specific cognitive function, mental health, psychological well-being, dialysis efficacy, and health-related quality of life in people with end-stage kidney disease receiving…
- Conditions
- Supportive Care, Exercise Adaptations, Exercise Training Therapy, Clinical Exercise
- Trial name
- EXCOG-HD (NCT07780175)
- Testing
- Resistance Training, Aerobic training, Combination Training
- Where
- Cyprus
- Volunteers
- 60 people
- Sponsor
- University of Thessaly
Hepatitis B
Safety of HEPLISAV™ Hepatitis B Virus Vaccine in End-stage Kidney Failure Patients
The purpose of this study is to find out if a new investigational hepatitis B virus vaccine, HEPLISAV™, is safe in patients at least 40 years of age who have progressive loss of kidney function with more advanced stage 3 (GFR ≤…
- Trial name
- NCT00426712
- Testing
- 1018 ISS immunostimulatory oligonucleotide with HBV surface antigen, Hepatitis B Vaccine (Recombinant)
- Where
- 4 sites in United States
- Volunteers
- 42 people
- Sponsor
- Dynavax Technologies Corporation
Chronic Kidney Disease, End-stage Renal Disease
Comparison of High Versus Low Bicarbonate Hemodialysis
This study will compare hemodialysis treatment with a standard, high-bicarbonate dialysis bath versus a lower bicarbonate dialysis bath, and will compare intradialytic acid-base changes and overall control of metabolic acidosis…
- Conditions
- Chronic Kidney Disease, End-stage Renal Disease, Metabolic Acidosis
- Trial name
- NCT02098356
- Testing
- Low Bicarbonate
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Albert Einstein College of Medicine
Arteriovenous Fistulae
Cohort Study on A Following-up System of Native Arteriovenous Fistulae
A cohort including more than 100 maintenance hemodialysis patients will be followed up according to a certain Following-up System of Native Arteriovenous Fistulae (AVF) prospectively.
- Trial name
- NCT02880761
- Testing
- Assessment guiding surgery and puncture for AVF
- Where
- China
- Volunteers
- 209 people
- Sponsor
- Capital Medical University
Renal Insufficiency, Chronic, Kidney Disease, Chronic
A Study of LY2928057 in Hemodialysis Participants
This study will evaluate the safety of LY2928057 and how LY2928057 affects hemoglobin in hemodialysis participants. This study will involve multiple doses of LY2928057 given during a 6 week period either after a participant…
- Trial name
- NCT01991483
- Testing
- LY2928057
- Where
- 4 sites in United States
- Volunteers
- 28 people
- Sponsor
- Eli Lilly and Company
Pulmonary Hypertension, Hemodialysis Complication
Sildenafil in Hemodialysis Patients With Pulmonary Hypertension
Sildenafil is a phosphodiesterase inhibitor that can exert a nitric oxide-mediated vasodilation effect, so it's considered one of the preferred agents especially in hypoxia induced pulmonary hypertension, can achieve pulmonary…
- Trial name
- NCT03763045
- Testing
- Sildenafil
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Kidney Failure, Chronic, Depression
Cognitive-behavioral (CBT) in ESRD Patients With Depression
Depression is common in end-stage renal disease (ESRD) patients and has a negative effect on the quality of life, functional ability, and mortality, with a prevalence rate as high as 20-25%.
- Conditions
- Kidney Failure, Chronic, Depression, Quality of Life
- Trial name
- NCT02011139
- Testing
- Cognitive-behavioral group therapy
- Where
- South Korea
- Volunteers
- 15 people
- Sponsor
- Seoul National University Boramae Hospital
Complication of Renal Dialysis, End Stage Renal Disease
A Study Testing the Use of a Perivascular Sirolimus Formulation (Sirogen) in ESRD Patients Undergoing AV Fistula Surgery
The primary study objective is to evaluate the benefit of the Sirolimus eluting Collagen implant (SeCI; Sirogen), a single dose prophylactic treatment delivered intraoperatively at the time of surgical creation of an…
- Conditions
- Complication of Renal Dialysis, End Stage Renal Disease, End Stage Kidney Disease, ESRD
- Trial name
- ACCESS2 (NCT05425056)
- Testing
- Sirolimus
- Where
- 22 sites in United States, United Kingdom
- Volunteers
- 136 people
- Sponsor
- Vascular Therapies, Inc.
Chronic Renal Failure, Hemodialysis
Effect of Malnutrition on the Prognosis in Hemodialysis Patients
The purpose of this study is to examined the effect of malnutrition and/or inflammation on atherosclerosis and prognosis in hemodialysis.
- Conditions
- Chronic Renal Failure, Hemodialysis, Malnutrition
- Trial name
- NCT00307983
- Where
- 2 sites in Japan
- Volunteers
- 600 people
- Sponsor
- University of Shizuoka
End-stage Renal Disease (ESRD)
Rheological Functions of Erythrocyte in ESRD
End-stage renal disease (ESRD) disrupts erythrocyte deformability due to osmotic imbalances, oxidative stress, and uremic toxins, leading to impaired microcirculation and oxygen transport.
- Trial name
- NCT06868888
- Testing
- Blood collection, Cardiopulmonary exercise testing (CPET)
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Renal Failure
Quanta Home Run Trial
The purpose of this study is to determine non-inferiority in safety and efficacy when Quanta SC+ is used in the self-care home environment compared to a hemodialysis facility.
- Trial name
- NCT04975880
- Testing
- SC+ Hemodialysis System
- Where
- 13 sites in United States
- Volunteers
- 46 people
- Sponsor
- Quanta Dialysis Technologies Ltd
End Stage Renal Failure, Surgery
A Study of Routine Versus Selective Use of Ultrasound Scanning Prior to Haemodialysis Fistula Surgery
Dialysis patients have their blood filtered by a machine as their kidneys no longer work. To get blood in and out of these patients it is possible to perform a surgical procedure to increase to size and durability of a vein in…
- Trial name
- NCT01004627
- Testing
- Arterial and venous duplex ultrasound examination
- Where
- United Kingdom
- Volunteers
- 98 people
- Sponsor
- Hull University Teaching Hospitals NHS Trust
End Stage Renal Disease
Improving The Nutritional Status Of The Malnourished Chronic Hemodialysis Patients In The State Of Tennessee
We propose to identify malnourished chronic kidney dialysis patients through a statewide effort and subsequently treat them based on a protocol (provision of oral nutritional supplementation) over a period of six (6) months.
- Trial name
- NCT00179153
- Testing
- Nepro nutritional supplement
- Where
- United States
- Volunteers
- 352 people
- Sponsor
- Vanderbilt University
Chronic Renal Failure
Incremental Hemodialysis as a Starting Way of Renal Replacement Therapy
The Hemodialysis Unit of the Hospital Ramon y Cajal is a pioneer in the implementation of a program of incremental hemodialysis, starting with two sessions a week in patients with residual renal function.
- Trial name
- NCT03302546
- Testing
- Incremental hemodialysis, Conventional hemodialysis
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
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