Clinical trials: Complication of Hemodialysis
End Stage Renal Failure on Dialysis
A Pilot Trial of Twice-weekly Versus Thrice-weekly Hemodialysis in Patients With Incident End-stage Kidney Disease
The optimal frequency of hemodialysis treatments in patients with incident end-stage kidney disease in not known. This pilot trial will randomize patients with incident end-stage kidney disease due to chronic kidney disease…
- Trial name
- TWOPLUS-HD (NCT03740048)
- Testing
- Hemodialysis, Patiromer Oral Product
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
CKD (Chronic Kidney Disease) Stage 5D
NGAL and Hepcidin Levels in Hemodialysis Patients in Assiut University Hospital
To assess the pattern of NGAL and Hepicidin in relation to anemia in End Stage Renal Disease Patients on regular hemodialysis in Assiut University Hospital and study the relation between both NGAL and Hepicidin.
- Trial name
- NCT04083664
- Testing
- NGAL and Hepcidin
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Assiut University
Hemodialysis, Renal Failure
Effect of N-Acetylcysteine on Residual Renal Function in Chronic Hemodialysis Patients
In our opinion, it is worth to check an ability of antioxidant therapy to produce a favorable effect on Residual Renal Function.
- Trial name
- NCT00507052
- Testing
- N-acetylcysteine
- Where
- Israel
- Sponsor
- Assaf-Harofeh Medical Center
End Stage Renal Disease
Events Before Death
Previous studies of the patients treated in RRI clinics suggest that hemodialysis patients undergo a certain consistent predictable pattern at the initiation of dialysis and before death.
- Trial name
- NCT01329055
- Where
- United States
- Volunteers
- 50,000 people
- Sponsor
- Renal Research Institute
Acute Kidney Injury, Sepsis
Labile Iron Removal by Adding the Iron Chelator MEX-CD1 to Dialysate in Sepsis-Associated Acute Kidney Injury
The goal of this clinical trial is to learn if adding the iron-binding drug MEX-CD1 to dialysis fluid can help remove excess iron in adults with sepsis-associated acute kidney injury (AKI) requiring dialysis who are in the…
- Trial name
- IRON-IC (NCT07236463)
- Testing
- Continuous veino-veinous dialysis with iron-chelator supplemented dialysate
- Where
- 2 sites in France
- Volunteers
- 14 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
End Stage Renal Disease
Effect of Omega-3 Fatty Acids on Oxidative Stress and Dyslipidemia in Pediatric Patients Undergoing Hemodialysis
The purpose of the study is to evaluate the effect of omega-3 fatty acids supplementation on pediatric patients undergoing hemodialysis via the measurement of the following before and after omega-3 administration:oxidative stress…
- Trial name
- NCT02581449
- Testing
- omega-3, empty soft gelatin capsules
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Chronic Kidney Disease, Kidney Failure
Indicating Direction and Angle for Cannulating of AV-fistula in Hemodialysis Patients
Arteriovenous fistula is the preferred access for hemodialysis, and cannulation using a "button-hole" technique is increasingly recommended.
- Trial name
- NCT01536548
- Testing
- Skin drawing, No skin drawing
- Where
- 8 sites in Norway
- Volunteers
- 83 people
- Sponsor
- Norwegian University of Science and Technology
End Stage Renal Disease, ESRD
Safety and Efficacy Assessments of NeoKidney® in ESRD Patients Treated With Short Daily Hemodialysis
The goal of this clinical investigation is to asses the safety and efficacy a new sorbent-based hemodialysis device, NeoKidney® in ESRD patients treated with short daily hemodialysis.
- Trial name
- FIH Caen (NCT06024135)
- Testing
- NeoKidney
- Where
- France
- Volunteers
- 5 people
- Sponsor
- Nextkidney S.A.
Chronic Kidney Disease 5D, Uremia; Chronic
ICHARUS: Italian Cooperative HemoAdsorption Study for Relief of Uremic Symptoms
Background: Many patients receiving maintenance hemodialysis continue to experience persistent uremic symptoms, such as pruritus, fatigue, sleep disorders, reduced physical performance, and impaired quality of life, despite…
- Trial name
- ICHARUS (NCT07522008)
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Azienda Ospedaliera Brotzu
End Stage Renal Disease
The Effects of Protein Supplementation and Resistance Exercise in Hemodialysis Patients
The objective of this study is to determine how protein supplementation, with or without exercise, affects functional capacity, strength, body composition, and physical activity in hemodialysis patients.
- Trial name
- NCT00179140
- Testing
- nutritional supplementation, exercise
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Vanderbilt University
Haemodialysis Complication
Combining Bioimpedance and Blood Volume Measurements in Haemodialysis
Around 60,000 patients in the UK are being treated for severe kidney failure. The most common treatment is haemodialysis (HD). An important part of HD is removing extra fluid from the body which the kidneys normally remove in…
- Trial name
- NCT03851185
- Where
- United Kingdom
- Volunteers
- 160 people
- Sponsor
- The Leeds Teaching Hospitals NHS Trust
Complication of Hemodialysis
REmoval of Free Light Chains. A COmpaRison of Three Different dialyzERs
Immunoglobulin light chains are classified as middle molecule uremic toxins able to interact with B lymphocyte membranes leading to the activation of transmembrane signaling.
- Trial name
- RECORDER (NCT02950389)
- Testing
- PMMA filter, HFR17 filter, F7 filter
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
End-stage Kidney Disease, Kidney Disease, Chronic
Safety, Tolerability, and Feasibility of Empagliflozin Therapy in Dialysis-dependent ESKD
The purpose of this study is to find out if empagliflozin, a new diabetic medication that has been shown to be very effective in lowering the risk of heart failure, is safe and tolerated in dialysis patients.
- Conditions
- End-stage Kidney Disease, Kidney Disease, Chronic, Dialysis, Diabetic
- Trial name
- NCT05614115
- Testing
- Empagliflozin
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of Utah
End Stage Renal Disease / Hemodialysis
Effectiveness of Mandala Coloring on State Mindfulness, Mood and Psychological Distress Among Patients Undergoing Hemodialysis
The goal of this study is to see if mandala coloring helps improve state mindfulness, mood and psychological distress in patients undergoing hemodialysis. The study will also compare mandala coloring with free-form coloring.
- Trial name
- NCT07561918
- Testing
- Mandala Coloring, Free-Form Drawing
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Kinnaird College for Women
Renal Dialysis, Kidney Failure, Chronic
Patient Activation in Dialysis
Patient activation refers to patients' willingness and ability to make independent actions to manage their health and care and requires knowledge, skill and confidence.
- Trial name
- PAMD (NCT04066140)
- Testing
- No intervention
- Where
- 36 sites in United States
- Volunteers
- 227 people
- Sponsor
- Satellite Healthcare
End-Stage Renal Disease
Impact of a Personal Digital Assistant (PDA) - Based Dietary Adherence Intervention on Interdialytic Weight Gain and Blood Pressure in Hemodialysis Patients
With this study the investigators will test, in a randomised clinical trial (RCT), the efficacy of a behavioral dietary adherence enhancement intervention paired with PDA-based dietary self-monitoring for controlling sodium…
- Trial name
- BalanceWise-HD (NCT00447408)
- Testing
- Standard hemodialysis dietary instruction, Behavioral counseling plus PDA-based self-monitoring of diet
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Pittsburgh
Complication of Hemodialysis
The Efficacy of Alcohol After Betadine and Combination of Alcohol and Betadine on Inflammation Vascular Access
The purpose of this study was to compare the efficacy of combination of alcohol and povidone iodine 10% and Alcohol 70% after povidone iodine 10% on inflammation and infection related to vascular access area in hemodialysis…
- Trial name
- NCT02263196
- Testing
- Alcohol and povidone iodine, combination of alcohol and betadin
- Where
- Iran
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Mashhad University of Medical Sciences
End Stage Renal Disease
Evaluation of the GORE® ACUSEAL Vascular Graft for Hemodialysis Access
This study is a prospective, non-randomized, multi-center evaluation of the performance of the GORE® ACUSEAL Vascular Graft. The study will enroll patients with End-Stage Renal Disease (ESRD), who are either currently receiving…
- Trial name
- ACUSEAL (NCT01173718)
- Testing
- GORE® ACUSEAL Vascular Graft
- Volunteers
- 138 people
- Sponsor
- W.L.Gore & Associates
Chronic Renal Failure
Docohexanoic Acid in Hemodialysis Patients
Docohexanoic acid (DHA), a dietary n-3 polyunsaturated fatty-acid omega-3 (n-3, PUFA), showed potential beneficial effects in reducing all-cause mortality in hemodialysis (HD) patients.
- Trial name
- NCT04536636
- Testing
- Docohexanoic acid, Control-No drug
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
End-Stage Renal Disease
Study of Home-Embedded Palliative Care for Hemodialysis- (and Peritoneal-) Dependent End-Stage Renal Disease
Home palliative care needs are often under-recognized in patients with End-Stage Renal Disease (ESRD). This pilot study is designed to evaluate the effectiveness of referrals to home palliative care services in improving patient…
- Trial name
- SHEPHERD 2 (NCT06144281)
- Testing
- Nudge for PHPC NP Referral
- Where
- United States
- Volunteers
- 315 people
- Sponsor
- University of Pennsylvania
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