Clinical trials: Complication of Hemodialysis
Chronic Kidney Disease, Chronic Renal Disease
Study of How the Dose of Dialysis is Affected by Dialysate Flow Rate
The purpose of this study is to look at how the dose of dialysis is affected by the rate at which dialysate flows through the dialyzer.
- Trial name
- NCT00962000
- Testing
- Dialysis Flow Rate Start 600mL/min, Dialysis Flow Rate Start 800mL/min
- Where
- 3 sites in United States
- Volunteers
- 42 people
- Sponsor
- Vantive Health LLC
Kidney Failure, Haemodialysis Fluid Adverse Reaction
BIS-guided Fluid Management in HD Patients
Hemodialysis (HD) is life-sustaining in kidney failure. However, adequate fluid status depends on precise estimation of dry weight (DW), which is a goal difficult to achieve.
- Trial name
- NCT05272800
- Testing
- Spectroscopy Bioimpedance Analysis, Clinical Examination alone
- Where
- Brazil
- Volunteers
- 110 people
- Sponsor
- Catholic University of Pelotas
Chronic Kidney Disease
Ticagrelor and Anti-inflammatory Effects
Antiplatelet treatment in patients with end stage renal disease (ESRD) on hemodialysis (HD) is still challenging because of bleeding and thrombotic complications.
- Trial name
- NCT02406911
- Testing
- Ticagrelor
- Where
- South Korea
- Volunteers
- 25 people
- Sponsor
- Kyunghee University Medical Center
Continuous Renal Replacement Therapy (CRRT), Acute Kidney Injury
Insights Into the Continuous Renal Replacement Therapy to Critical Ill Patients
This is a multinational, prospective, observational study designed to characterize patient demographics, prescription parameters, and process measures of continuous renal replacement therapy (CRRT) in intensive care units (ICUs)…
- Conditions
- Continuous Renal Replacement Therapy (CRRT), Acute Kidney Injury, Renal Dialysis, Critical Illness
- Trial name
- iCRRT (NCT07365111)
- Testing
- continuous renal replacement therapy
- Where
- Canada
- Volunteers
- 100,000 people
- Sponsor
- University of Alberta
Non-Dialysis Dependent Severe Renal Dysfunction, Cardiovascular Disease
Preop Hemodialysis or Intraop Ultrafiltration for Patients With Severe Renal Dysfunction Undergoing Open Heart Surgery
The purpose of this study is to determine whether preoperative hemodialysis or intraoperative modified ultrafiltration are effective for patients with non-dialysis dependent severe renal dysfunction undergoing open heart surgery.
- Trial name
- SeRenaD-CPB (NCT00720967)
- Testing
- Open Heart Surgery (OHS), Intraoperative Modified Ultrafiltration (MUF), Hemodialysis (HD)
- Where
- 7 sites in France, Germany and 3 more
- Volunteers
- 450 people
- Sponsor
- University Hospital, Geneva
Cardiovascular Diseases, Kidney Failure, Chronic
Pharmacokinetics of Dabigatran Etexilate (Pradaxa®) During Haemodialysis
The current study will allow the assessment of pharmacokinetics, pharmacodynamics, elimination rate and clearance of dabigatran etexilate during and following haemodialysis in ESRD patients.
- Trial name
- NCT01241539
- Testing
- Dabigatran etexilate
- Where
- Germany
- Volunteers
- 7 people
- Sponsor
- Boehringer Ingelheim
Complication of Renal Dialysis, End Stage Renal Disease
A Study Testing the Use of a Perivascular Sirolimus Formulation (Sirogen) in ESRD Patients Undergoing AV Fistula Surgery
The primary study objective is to evaluate the benefit of the Sirolimus eluting Collagen implant (SeCI; Sirogen), a single dose prophylactic treatment delivered intraoperatively at the time of surgical creation of an…
- Conditions
- Complication of Renal Dialysis, End Stage Renal Disease, End Stage Kidney Disease, ESRD
- Trial name
- ACCESS2 (NCT05425056)
- Testing
- Sirolimus
- Where
- 22 sites in United States, United Kingdom
- Volunteers
- 136 people
- Sponsor
- Vascular Therapies, Inc.
Chronic Renal Failure, Haemodialysis, Haemodiafiltration, Haemofiltration
Catheter Dysfunction Rate in Patients Undergoing Kidney Replacement Therapy. Evaluation of the Safety and Efficacy of Anti-reflux Valves Without Heparin Lock Solution
Catheter dysfunction and infections are the most common complications observed among patients with dialysis catheters for long-term dialysis ( CDLD ) .
- Conditions
- Chronic Renal Failure, Haemodialysis, Haemodiafiltration, Haemofiltration, Kidney Replacement Therapy, Catheter Infection, Catheter Dysfunction, Catheter Related Bloodstream Infections
- Trial name
- DUKE (NCT06259266)
- Testing
- Anti-reflux valve for dialysis catheter
- Where
- France
- Sponsor
- University Hospital, Clermont-Ferrand
Hemodialysis Complication
Outcome and Complications of Regular Hemodialysis
Assessment of the major hemodialysis outcomes which are vascular access events, mortality and hospitalization Quality of life in end stage renal disease (ESRD) patients undergoing regular hemodialysis in upper Egypt and analysis…
- Trial name
- NCT06586853
- Volunteers
- 300 people
- Sponsor
- Assiut University
Secondary Hyperparathyroidism Due to Renal Causes, Chronic Kidney Diseases
Safety, Efficacy, PK and PD of CTAP101 (Calcifediol) ER Capsules for SHPT in HD Patients VDI
Safety, Efficacy, PK and PD of CTAP101 (calcifediol) ER Capsules for SHPT in HD Patients VDI
- Conditions
- Secondary Hyperparathyroidism Due to Renal Causes, Chronic Kidney Diseases, Vitamin D Deficiency, Stage 5 Chronic Kidney Disease
- Trial name
- NCT03602261
- Testing
- Calcifediol Oral Capsule
- Where
- 18 sites in United States
- Volunteers
- 44 people
- Sponsor
- OPKO Health, Inc.
Intradialytic Fatigue, Chronic Kidney Disease
Manual Acupuncture for Intradialytic Fatigue in CKD Patients
This study aims to evaluate the immediate effects of acupuncture therapy at three specific acupuncture points (PC6, ST36, and KI3) on intradialytic fatigue in patients with chronic kidney disease undergoing regular hemodialysis.
- Conditions
- Intradialytic Fatigue, Chronic Kidney Disease, Acupuncture
- Trial name
- NCT07887386
- Testing
- Manual Acupuncture
- Where
- Indonesia
- Volunteers
- 19 people
- Sponsor
- Universitas Indonesia
Nursing Caries, Hemodialysis Complication
Muscle Cramps in Hemodialysis Patients: A Randomized Controlled Trial
Muscle cramps are a common and distressing issue among hemodialysis patients, significantly impacting their quality of life. Non-pharmacological approaches are increasingly being explored to alleviate these symptoms.
- Conditions
- Nursing Caries, Hemodialysis Complication, Exercise Addiction
- Trial name
- NCT06866470
- Testing
- relaxation group, massage
- Where
- Turkey (Türkiye)
- Volunteers
- 79 people
- Sponsor
- University of Yalova
End-Stage Renal Disease
Anti-Cytokine Therapy for Hemodialysis InflammatION
Anti-Cytokine Therapy for Hemodialysis InflammatION (ACTION) is a phase II multi-center study to evaluate the safety and tolerability of anakinra, an IL-1 receptor antagonist, for patients treated with maintenance hemodialysis.
- Trial name
- ACTION (NCT03141983)
- Testing
- Anakinra
- Where
- 4 sites in United States
- Volunteers
- 80 people
- Sponsor
- University of Pennsylvania
Kidney Failure, Chronic
Trial of Aerobic Exercise in Patients Undergoing Outpatient Hemodialysis
Randomized controlled trial comparing effects of ergometer exercise during hemodialysis to effects of pedometer use outside of hemodialysis on exercise capacity, functional status, quality of life and adequacy of hemodialysis.
- Trial name
- NCT00492362
- Testing
- ergometer exercise during hemodialysis, pedometer activity outside of hemodialysis
- Where
- 4 sites in Canada
- Volunteers
- 60 people
- Sponsor
- University of Manitoba
Chronic Kidney Diseases
Effect of Exercise on Vessel Diameter in Hemodialysis Patients
In this study, 100 hemodialysis patients aged between 18-65 were examined. Participants were randomly divided into two groups: the exercise group and the control group.
- Trial name
- NCT06428773
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Kirsehir Ahi Evran Universitesi
End Stage Renal Disease
24 Hour Use of the Wearable Artificial Kidney
This is a prospective, interventional study designed to provide preliminary data on the human use of the WAK. Up to 10 subjects currently receiving intermittent hemodialysis (HD) treatment three times per week for end-stage renal…
- Trial name
- WAK US 1 (NCT02280005)
- Testing
- WAK Treatment
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Blood Purification Technologies, Inc.
Iron Deficiency Anemia (IDA), ESRD (End Stage Renal Disease)
Management of Iron Deficiency Anemia in Hemodialysis Patients
The aim of this interventional study is to assess the effectiveness of oral lactoferrin in improving hemoglobin levels and correcting iron deficiency anemia in patients with end-stage renal disease (ESRD) on dialysis and also…
- Trial name
- NCT07706582
- Testing
- Lactoferrin, IV iron sucrose
- Where
- Egypt
- Volunteers
- 108 people
- Sponsor
- Beni-Suef University
Complication of Hemodialysis
The Efficacy of Alcohol After Betadine and Combination of Alcohol and Betadine on Inflammation Vascular Access
The purpose of this study was to compare the efficacy of combination of alcohol and povidone iodine 10% and Alcohol 70% after povidone iodine 10% on inflammation and infection related to vascular access area in hemodialysis…
- Trial name
- NCT02263196
- Testing
- Alcohol and povidone iodine, combination of alcohol and betadin
- Where
- Iran
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Mashhad University of Medical Sciences
Chronic Kidney Diseases
Removal of Beta Blocker Drugs by Hemodialysis
Eight maintenance hemodialysis patients are given one of four beta blocker drugs (atenolol, bisoprolol, carvedilol, metoprolol) three hours prior to a hemodialysis session.
- Trial name
- NCT03361280
- Testing
- Beta blocker
- Volunteers
- 8 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
ESRD, Sleep Apnea
Identification of Desaturation Episodes by Means of Continuous Measurement of Oxygen Saturation During Hemodialysis
The clinical diagnosis of sleep apnea is difficult among ESRD patients since the characteristic clinical features of sleep apnea may be absent and since sleep-related symptoms, such as fatigue and sleepiness, may be attributed to…
- Conditions
- ESRD, Sleep Apnea, Oxygen Deficiency
- Trial name
- NCT02987179
- Testing
- Observational
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Renal Research Institute
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