Clinical trials: Complication of Ventilation Therapy
Respiratory Distress Syndrome, Newborn, Premature Birth
SURFAXIN® Treatment for Prevention of Bronchopulmonary Dysplasia (BPD) in Very Low Birth Weight (VLBW) Infants.
SURFAXIN® (lucinactant) treatment will be examined in very low birth weight infants to prevent development of chronic lung disease, commonly known as bronchopulmonary dysplasia (BPD), in premature infants who have required…
- Conditions
- Respiratory Distress Syndrome, Newborn, Premature Birth, Bronchopulmonary Dysplasia
- Trial name
- NCT00215540
- Testing
- Lucinactant 175 mg/kg, Lucinactant 90 mg/kg
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- Windtree Therapeutics
Pneumonia, Ventilator Associated
Pilot Study of Lateral Rotation Interventions for Efficacy and Safety in ICU Care
Intensive care unit (ICU) patients on respirators are at high risk for preventable pulmonary complications (PPC). Turning these patients from side to side may reduce PPC, but carries the burden of decreases in blood pressure and…
- Trial name
- NCT00542321
- Testing
- Manual turn, kinetic therapy bed
- Volunteers
- 16 people
- Sponsor
- The University of Texas Health Science Center, Houston
Meconium Aspiration
Phase III Randomized Study of Lucinactant in Full Term Newborn Infants With Meconium Aspiration Syndrome
OBJECTIVES: Evaluate the safety and efficacy of lucinactant administered by bronchoalveolar lavage (BAL) in the treatment of meconium aspiration syndrome (MAS) in newborn infants.
- Trial name
- NCT00004500
- Testing
- Lucinactant, Standard Care
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- Windtree Therapeutics
Obstructive Sleep Apnea, Delayed Emergence From Anesthesia
Evaluation of Modafinil vs Placebo for Treatment of Anesthesia Delayed Emergence in Obstructive Sleep Apnea
The purpose of this study is to determine whether modafinil use in patients with obstructive sleep apnea will improve postoperative delayed emergence after general anesthesia.
- Trial name
- ModOSA (NCT02494102)
- Testing
- Modafinil
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Milton S. Hershey Medical Center
Postoperative Atelectasis, Postoperative Hypoxemia
REMINDers for Incentive Spirometry in PACU (REMIND-IS in PACU)
The purpose of this study is to determine if the frequency of use of incentive spirometry during the stay in the Post-Anesthesia Care Unit (PACU) increases with visual and auditory electronic reminders, as compared to not having…
- Conditions
- Postoperative Atelectasis, Postoperative Hypoxemia, Postoperative Pneumonia, Postoperative Pulmonary Complications
- Trial name
- NCT06304493
- Testing
- Alarms
- Where
- United States
- Volunteers
- 231 people
- Sponsor
- University of Colorado, Denver
Prematurity, Respiratory Distress Syndrome
Curosurf and Survanta Treatment(CAST)of RDS in Very Premature Infants
Approval of surfactant by the FDA in 1989 for the treatment of Respiratory Distress Syndrome (RDS) in premature infants greatly improved survival rates.
- Conditions
- Prematurity, Respiratory Distress Syndrome, Patent Ductus Arteriosus
- Trial name
- CAST (NCT00767039)
- Testing
- Survanta (beractant), Curosurf (poractant)
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Alan Fujii
Ventilation Therapy; Complications
Comparison of Effectiveness of Mask Ventilation and Endotracheal Tube in Pharynx (TTIP) in Patients With Potential Difficult Airway
The purpose of this study is to determine the efficacy of TTIP-first ventilation and to compare the efficacy of TTIP first ventilation with the current practice of mask-first ventilation
- Trial name
- NCT05005390
- Testing
- TTIP ventilation, Mask Ventilation
- Where
- United States
- Volunteers
- 147 people
- Sponsor
- The University of Texas Health Science Center, Houston