Clinical trials: Complications, Postoperative
Postoperative Pain
Postoperative Pain Control in Children Undergoing Laparoscopic Appendectomy: Peripheral Nerve Block Versus Local Anesthetic
After undergoing a laparoscopic appendectomy, a child may experience some degree of pain in the postoperative period. As a routine part of the procedure, surgeons inject local anesthetic where the laparoscopic ports are placed.
- Trial name
- NCT01662401
- Testing
- Bupivacaine
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Pain, Postoperative, Postoperative Nausea and Vomiting
Anesthetic Premedication With a Cannabis Extract (Cannapremed)
Clinical evidence about the effects of cannabis in a perioperative setting or for the management of acute pain is rather scarce, mostly consisting of case report-based opinions on adverse events during or after general anesthesia…
- Conditions
- Pain, Postoperative, Postoperative Nausea and Vomiting, Anxiety
- Trial name
- Cannapremed (NCT02283281)
- Testing
- Tetrahydrocannabinol, Dummy oromucosal
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Hadassah Medical Organization
Ventilator-Induced Lung Injury, Ventilator Lung
How To Prevent Ventilator-Related Lung Damage in Intraoperative Mechanical Ventilation? Pcv or Vcv ?
Introduction: Intraoperative Mechanical Ventilation practices can lead to ventilator-associated lung injury (VILI) and postoperative pulmonary complications in healthy lungs.
- Conditions
- Ventilator-Induced Lung Injury, Ventilator Lung, Mechanical Ventilation Complication, Postoperative Complications
- Trial name
- NCT05814081
- Testing
- Position/Ventilation
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Abdominal Obesity, Postoperative Pain
Transversus Abdominis Plan Block Versus Rectus Sheath Block
The investigator aims to compare the analgesic efficacy of Transversus Abdominis Plan Block and Rectus Sheath Block which are used to prevent intraoperative and postoperative pain and reduce the use of opioid in abdominoplasty…
- Conditions
- Abdominal Obesity, Postoperative Pain, Postoperative Complications
- Trial name
- NCT06897345
- Testing
- transversus abdominis plane block, rectus sheat block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Covid-19, SARS-CoV2
SURgical Outcomes in COvid Patients - the SUROCO Multicenter Cohort Study (COVID-19)
Overall mortality of COVID-19 is variable and has been reported to be between less than 1% and 7%. Many authors around the world also reported data on hospitalization rate, need for intensive care unit (ICU) care and need for…
- Conditions
- Covid-19, SARS-CoV2, Surgery, Surgical Procedure; Complications, Late Effect of Complications
- Trial name
- SUROCO (NCT04458337)
- Where
- Canada
- Volunteers
- 318 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Postoperative Pain, Postoperative Analgesia
A Predictive Model for Postoperative Analgesic Requirements After Abdominal Surgery
Postoperative pain remains a common challenge after abdominal surgery despite the use of standard multimodal pain management strategies.
- Conditions
- Postoperative Pain, Postoperative Analgesia, Opioid Analgesic Requirement, Pain Management After Abdominal Surgery
- Trial name
- NCT07803575
- Testing
- Intravenous Morphine Patient-Controlled Analgesia
- Where
- Malaysia
- Volunteers
- 65 people
- Sponsor
- Chaw Sook Hui
Postoperative Complications
Impact of Local Anesthesia on Postbronchoscopy Fever: a Randomised Controlled Study
Impact of Local Anesthesia on Postbronchoscopy Fever: a Randomised Controlled Study
- Trial name
- NCT02961075
- Testing
- local surface anesthesia, Laryngeal tube
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- The Second Affiliated Hospital of Dalian Medical University
Surgery, Delirium - Postoperative
VR-Based Cognitive Stimulation Games for Delirium Prevention
This trial aims to evaluate the feasibility, safety, and acceptability of a virtual reality (VR)-based cognitive stimulation game to reduce postoperative delirium among older surgical patients at high risk due to pre-existing…
- Conditions
- Surgery, Delirium - Postoperative, Delirium
- Trial name
- NCT07641153
- Testing
- Virtual Reality Software, Virtual Reality movies, Nurse led control arm
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- The Methodist Hospital Research Institute
Esophageal Cancer
Decreasing Postoperative Complications by Goal-Directed Fluid Therapy During Esophageal Resection
Surgery for cancer of the esophagus is associated with a high risk of postoperative complications. It has been shown that the risk of postoperative complications can be decreased by optimising the amount and type of infusion…
- Trial name
- NCT01416077
- Testing
- fluid optimisation
- Where
- Sweden
- Volunteers
- 64 people
- Sponsor
- University Hospital, Linkoeping
Anesthesia Recovery Periods, Anesthesia Complication
Bispectral Index and Emergence Agitation in Spinal Surgeries
Recovery and emergence agitation is a problem that occurs after anesthesia and requires urgent intervention. The effects of changes in EEG waves during anesthesia or undesirable deep periods in Bispectral index (BIS) monitoring…
- Conditions
- Anesthesia Recovery Periods, Anesthesia Complication, Electroencephalography
- Trial name
- NCT06217341
- Testing
- In the study, bispectral index monitoring and follow-up will be applied to both groups.
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bozok University
Ileostomy, Colorectal Surgery
Early vs Standard Ileostomy Reversal
This randomized controlled trial compares early (8 weeks) versus standard (12 weeks) ileostomy reversal in patients with confirmed anastomotic healing, evaluating postoperative complications and recovery outcomes.
- Trial name
- NCT07601594
- Testing
- Ileostomy reversal
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- Gulab Devi Hospital
Cervical Cancers
A Clinical Study Comparing Chemotherapy Combined With PD-1 Inhibitor Versus Concurrent Chemoradiotherapy in Cervical Cancer Patients With Positive Lymph Nodes After Surgery: A Multicenter Randomized Controlled Clinical Trial
This study aims to conduct a prospective, multicenter, randomized controlled trial targeting patients with cervical cancer who have been pathologically confirmed to have lymph node metastasis after surgery.
- Trial name
- NCT06866951
- Testing
- Chemo-immunotherapy, CCRT
- Where
- China
- Sponsor
- Women's Hospital School Of Medicine Zhejiang University
Postoperative Delirium
Digitalized Clinical Decision Support for the Prevention of Postoperative Delirium (POD)
The project aims to improve patient safety, reduce barriers to the implementation of current guideline recommendations, reduce workload in clinics, increase efficiency in work processes and close gaps in care.
- Trial name
- NCT06445153
- Testing
- Intervention with clinical decision support system
- Where
- 4 sites in Germany
- Volunteers
- 844 people
- Sponsor
- Charite University, Berlin, Germany
Osteoarthritis, Knee, Osteoarthritis, Hip
Wound Closure Materials and Techniques in Hip and Knee Arthroplasty
This prospective randomized clinical study aims to evaluate the effects of different suture materials and wound closure techniques on wound healing, functional outcomes, and postoperative complications in patients undergoing…
- Trial name
- NCT07439575
- Testing
- Barbed Suture Wound Closure, Conventional Suture Wound Closure
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Bahattin Kemah
Driving Pressure, Neuromuscular Blockade Monitoring
Effect of Neuromuscular Block Depth on Driving Pressure and Postoperative Respiratory Events in Abdominal Surgeries
This randomized controlled study aims to evaluate the effects of deep versus moderate neuromuscular blockade on intraoperative driving pressure and the development of postoperative critical respiratory events in patients…
- Conditions
- Driving Pressure, Neuromuscular Blockade Monitoring, Postoperative Respiratory Complications
- Trial name
- NCT07464288
- Testing
- Rocuronium
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Postoperative Pain, Mandibular Molar Extraction
Effect of Intraoperative Tetracycline on Postoperative Pain After Mandibular Molar Extraction
Postoperative pain is a common complication following mandibular molar extraction and can negatively affect patient comfort and recovery.
- Conditions
- Postoperative Pain, Mandibular Molar Extraction, Tooth Extraction
- Trial name
- TETRAMOL (NCT07738861)
- Testing
- Tetracycline, No Intrasocket Medicament
- Where
- Pakistan
- Volunteers
- 74 people
- Sponsor
- CMH Lahore Medical College and Institute of Dentistry
Post-Operative Nausea and Vomiting, Breast Cancer
Intraoperative Acupoint Stimulation to Prevent Post-Operative Nausea and Vomiting (PONV)
The goal of this clinical research study is to learn if light electrical stimulation to the wrist area during surgery is feasible in women having breast surgery.
- Trial name
- NCT02473042
- Testing
- Electrical Stimulation, Zofran, Dexamethasone
- Where
- United States
- Volunteers
- 188 people
- Sponsor
- M.D. Anderson Cancer Center
Nausea, Vomiting
Comparison of Aprepitant Versus Aprepitant and Transdermal Scopolamine for Preventing Postoperative Nausea and Vomiting
The purpose of this study is to compare the incidence of nausea, vomiting, need for rescue medication, prolonged PACU time, and unplanned hospital admission in patients with high risk for post-operative nausea and vomiting (PONV)…
- Trial name
- NCT00717054
- Testing
- Aprepitant, Scopolamine
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Drexel University
Postoperative Pain
Predictors of Postoperative Pain
This is a retrospective chart review using TriHealth Electronic Privacy Identification Center (EPIC) and previously developed databases for TriHealth Institutional Review Board (IRB) approved research studies within the Division…
- Trial name
- NCT02996994
- Volunteers
- 364 people
- Sponsor
- TriHealth Inc.
Rehabilitation, Pain, Postoperative
Single Site Versus Multi Site Robotic Hysterectomy
Robotic single site surgery (R-SSH) is a novel technique, which may be superior to multi site hysterectomy (R-MSH) in select patients regarding cosmesis and postoperative pain.
- Conditions
- Rehabilitation, Pain, Postoperative, Wound Infection
- Trial name
- NCT03662451
- Testing
- Robotic assisted hysterectomy
- Where
- Denmark
- Sponsor
- Herning Hospital
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