Clinical trials: Complications, Postoperative
Intra-Operative Injury - Other, Post Operative Hemorrhage
Preoperative Hexakapron Reduces Bleeding in Bariatric Surgery
Prophylactic use of tranexamic acid to reduce intra and postoperative bleeding in primary sleeve gastrectomy procedures will be studied.
- Conditions
- Intra-Operative Injury - Other, Post Operative Hemorrhage, Tranexamic Acid
- Trial name
- PHORBBS (NCT03085394)
- Testing
- tranexamic acid
- Where
- Israel
- Volunteers
- 152 people
- Sponsor
- Sheba Medical Center
Postoperative Pain, Acute
Comparison of the Effects of Tenoxicam and Paracetamol on Postoperative Pain
Postoperative pain is generally caused by inflammation and oedema related to tissue trauma. Surgical tissue trauma is caused by many factors such as cotery-related burns, surgical incisions, dissections, and instrumental…
- Trial name
- NCT05508451
- Testing
- Double jaw surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Postoperative Pain
NALDEBAIN for Postoperative Pain Management in Take Down of Anastomosis
NALDEBAIN ER injection, invented by Taiwanese, launched in 2017, is a nalbuphine synthetic prodrug with oil-based solution to extend the release in human body by intramuscular injection.
- Trial name
- NCT03854851
- Testing
- Naldebain, Morpine
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- China Medical University Hospital
Pain, Postoperative, Carpal Tunnel Syndrome
The Effect Of An Anesthetic Procedure On Post Operative Pain Management In Carpal Tunnel Release
Carpal Tunnel Syndrome patients undergoing carpal tunnel release surgery performed by the PI will receive intra-operative injections of bupivacaine (Marcaine).
- Trial name
- CTR (NCT03729375)
- Testing
- 10cc injection of bupivacaine, 20cc injection of bupivacaine
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of South Florida
Surgical Site Infection, Vaginal Cuff Cellulitis
Prevention of Vaginal Cuff Infection After Hysterectomy by Addition of Vaginal Clindamycin
This study seeks to determine ways to reduce the hospitals surgical site infection rate during hysterectomy operations.
- Conditions
- Surgical Site Infection, Vaginal Cuff Cellulitis, Bacterial Vaginosis
- Trial name
- NCT07888101
- Testing
- Clindamycin Vaginal Gel
- Where
- United States
- Volunteers
- 900 people
- Sponsor
- Baylor Research Institute
Cerebral Palsy, Hip Dysplasia
Pain Injection Versus Epidural Anesthesia for Hip Surgery in Pediatric Patients With Cerebral Palsy
Pain management in pediatric patients presents a difficult challenge. Unlike adults, pediatric patients often cannot communicate their pain management needs clearly.
- Conditions
- Cerebral Palsy, Hip Dysplasia, Pain, Postoperative
- Trial name
- NCT06189781
- Testing
- Ropivacaine injection, Bupivacaine, lidocaine, ropivacaine
- Where
- 4 sites in United States
- Volunteers
- 90 people
- Sponsor
- University of California, Los Angeles
Pain, Postoperative, Knee Pain Chronic
Ultrasound-guided Genicular Nerve Block for Total Knee Arthroplasty (GenTKR)
Knee Osteoarthritis affects one third of the population over 65 years old. Total knee arthroplasty (TKA) has become one of the most frequent surgical procedures in the world.
- Trial name
- GenTKR (NCT04024319)
- Testing
- Genicular Nerve Block
- Where
- Spain
- Volunteers
- 35 people
- Sponsor
- Hospital Clinic of Barcelona
Post Operative Pain, Acute
Effect of Two Different Concentrations of Sodium Hypochlorite on Post-Operative Pain Following Single-Visit Root Canal Treatment
This randomized controlled trial aims to evaluate the effect of two different concentrations of sodium hypochlorite (2.5% and 5.25%) on post-operative pain following single-visit root canal treatment.
- Trial name
- NaOCl-RCT (NCT07618182)
- Testing
- Sodium Hypochlorite Irrigation
- Volunteers
- 116 people
- Sponsor
- College of Physicians and Surgeons Pakistan
Cervical Cancer
Optimization of Postoperative Adjuvant Therapy for Cervical Cancer Based on MRD(Minimal Residual Disease)
This study is a prospective cohort clinical trial that aims to investigate the safety and efficacy of a combined chemoradiotherapy and immunotherapy treatment for early postoperative cervical cancer.
- Trial name
- NCT05872724
- Testing
- Chemoradiotherapy + Adjuvant chemotherapy and Zimberelimab, Chemoradiotherapy (small pelvic) + Zimberelimab
- Where
- China
- Volunteers
- 32 people
- Sponsor
- Suzhou Municipal Hospital
Postoperative Complications
Saline Versus Lactated Ringer's Solution: The SOLAR Fluid Trial
Perioperative volumes of saline cause a mild acidosis compared with buffered fluids. On the other hand, saline administration maintains plasma osmolality and better repletes vascular volume which is an important goal of…
- Trial name
- NCT02565420
- Testing
- Normal saline, Lactated Ringer's solution
- Where
- United States
- Volunteers
- 8,616 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Emergence Delirium
The Effect of Binaural Sound on the Occurrence of Emergence Delirium in Children Undergoing Strabismus Surgery
The hypothesis of this study is that providing continuous binaural beats with a phase difference in alpha frequency during anesthesia can reduce the incidence of emergence agitation in pediatric patients.
- Trial name
- NCT05883280
- Testing
- Binaural beats
- Where
- South Korea
- Volunteers
- 74 people
- Sponsor
- Seoul National University Hospital
Hemorrhoids, Postoperative Pain
Ultrasound-guided Pudendal Nerve Block for Pain After Hemorrhoidectomy
The goal of this clinical trial is to investigate the effects of ultrasound-guided pudendal nerve block on postoperative pain, opioid consumption, and quality of recovery in patients receiving Ferguson hemorrhoidectomy.
- Trial name
- NCT05889962
- Testing
- Pudendal nerve block
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Taipei Medical University Hospital
Stroke, Cerebral Venous System
Study of Cerebral Venous System in Acute Ischemic Stroke Patients Receiving Reperfusion Therapy
The VAST study is a single-center prospective observational study that enrolled individuals with acute ischemic stroke (AIS) within 24 hours onset.
- Conditions
- Stroke, Cerebral Venous System, Reperfusion Injury
- Trial name
- VAST (NCT03838289)
- Testing
- multimodal magnetic resonance imaging or computed tomography
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Post Operative Pain
Systemic Lidocaine Infusion for Pain Control in Ventral Hernia
Ventral hernia repair leads to more than expected pain. This is thought to be secondary to nerve pain at the lateral transfixion sutures. Systemic lidocaine given pre-op has in other situations decreased neurogenic pain.
- Trial name
- NCT03484650
- Testing
- Lidocaine Hydrochloride
- Where
- United States
- Sponsor
- Carilion Clinic
Post Operative Pain, Acute, Renal Transplant Donor of Left Kidney
Effectiveness of Thread Embedding Acupuncture Analgesia at the EX-B2 Point Combined With Standard Therapy After Laparoscopic Living Donor Nephrectomy
Kidney transplantation is the main option besides hemodialysis and continuous ambulatory peritoneal dialysis (CAPD) to prolong and improve the quality of life for patients with end-stage renal disease.
- Conditions
- Post Operative Pain, Acute, Renal Transplant Donor of Left Kidney, Quality of Life, Acupuncture Analgesia
- Trial name
- NCT06197620
- Testing
- Thread embedding acupuncture and standard therapy
- Where
- Indonesia
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Cardiac Surgery, Postoperative Pain
Ultrasound-Guided Serratus Posterior Superior Intercostal Plane Block for Cardiac Surgery
This prospective, randomized, controlled study aims to evaluate the effects of ultrasound-guided bilateral single-shot serratus posterior superior intercostal plane (SPSIP) block on postoperative recovery and pain management in…
- Conditions
- Cardiac Surgery, Postoperative Pain, Postoperative Recovery After Cardiac Surgery
- Trial name
- NCT07785323
- Testing
- Serratus posterior superior intercostal plane block, Standard Perioperative Care
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Burak Çilingir
Postoperative Cognitive Dysfunction
Transcutaneous Electrical Acupoint Stimulation for Postoperative Cognitive Dysfunction
Postoperative cognitive dysfunction (POCD) is one of the common complications of cancer patients after operation with a 8.9%-46.1% incidence, which severely affecting patients' postoperative recovery, increasing the medical cost…
- Trial name
- NCT04606888
- Testing
- Transcutaneous electrical acupoint stimulation
- Where
- China
- Volunteers
- 64 people
- Sponsor
- Subei People's Hospital of Jiangsu Province
Perioperative Care, EEG Power Spectra
Extended Emergence Strategy on Post-Anesthesia Care Unit Events After Outpatient Orthopedic Surgery
The goal of this clinical trial is to learn if an extended emergence from anesthesia can improve recovery room (Post-Anesthesia Care Unit or PACU) outcomes in lower-leg or foot surgery with nerve blocks.
- Conditions
- Perioperative Care, EEG Power Spectra, Delirium - Postoperative
- Trial name
- PACU-EMERGE (NCT07533370)
- Testing
- Standard of Care EEG-Guided Emergence, Extended EEG Emergence Trajectory
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Harrison Shong-Wen Chow
Pain, Postoperative
Ultrasound Image Quality of the Brachial Plexus at the Interscalene Space Before and After Shoulder Arthroscopy
Ultrasound guided interscalene nerve blockade with local anesthesia is a standard regional anesthetic technique for providing postoperative analgesia during shoulder arthroscopy and wide variety of shoulder procedures.
- Trial name
- NCT03657173
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Mayo Clinic
Postoperative Pain, Abdominal Hysterectomy
Effect of Different Volumes of Erector Spinae Plane Block on Postoperative Opioid Consumption After Total Abdominal Hysterectomy
his study aims to investigate the effects of different volumes of ultrasound-guided erector spinae plane block (ESPB) on postoperative pain and opioid consumption in patients undergoing total abdominal hysterectomy.
- Conditions
- Postoperative Pain, Abdominal Hysterectomy, Pain
- Trial name
- NCT07533760
- Testing
- Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Şule Arıcan
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