Clinical trials: Complications, Postoperative
Postoperative Cardiovascular Complications
Preoperative BNP as Biomarker of Postoperative Cardiovascular Complications
BNP is a hormone that predicts preoperatively the occurrence of postoperative cardiovascular complications. In practice, the problem is that the practitioner don't know the most opportune moment for the preoperative sample or…
- Trial name
- BNP (NCT02570607)
- Testing
- BNP dosage
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Surgical Wound Infection
Parenteral Antibiotics Compared to Combination of Oral and Parenteral Antibiotics in Colorectal Surgery Prophylaxis
Routine antibiotics for the intravenous and oral prophylaxis of colorectal surgery will be used. Experimental group: Patients undergoing elective colorectal surgery that involves, colonic resection.
- Trial name
- ORALEV (NCT02505581)
- Testing
- Extra dosage - cefuroxime (750mg) I.V, Colorectal Surgery, Ciprofloxacin 750 mg oral
- Where
- 3 sites in Spain
- Volunteers
- 536 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Cesarean Section Complications
Magnesium Sulphate Versus Dexamethasone With TAP Block for Post-Cesarean Analgesia
This randomized, double-blind, controlled clinical trial will compare the effectiveness of a single intravenous dose of magnesium sulphate versus dexamethasone as an adjuvant to ultrasound-guided transversus abdominis plane (TAP)…
- Trial name
- NCT07773220
- Testing
- Magnesium Sulphate 500 mg, Dexamethasone
- Volunteers
- 80 people
- Sponsor
- Khyber Teaching Hospital
Cesarean Section
The Effect of Forced Air Warming During Cesarean Section on Postoperative Infectious Morbidity
The purpose of this study will be to assess whether forced air warming decreases the rate of surgical site infections following cesarean section.
- Trial name
- NCT00696462
- Testing
- forced-air warming
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Vanderbilt University
Postoperative Nausea and Vomiting
The Effect of Electroacustimulation on Postoperative Nausea, Vomiting and Pain in Outpatient Plastic Surgery Patients
Introduction: Current rates of postoperative nausea and vomiting (PONV) experienced by outpatient surgery patients are as high as 20-30%.
- Trial name
- NCT00941005
- Testing
- Electroacustimulation
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Analgesia, Pain, Postoperative
Effects of Intraoperative Magnesium Sulfate on Perioperative Pain Relief After Spine Surgery
The treatment of postoperative pain is increasingly based on a multimodal approach and although opioids remain the drug of choice, they are often used in combination with other analgesics (paracetamol, cyclooxygenase inhibitors…
- Conditions
- Analgesia, Pain, Postoperative, Spine Disease
- Trial name
- NCT04161729
- Testing
- Magnesium Sulfate, Isotonic saline 0.9%
- Where
- Greece
- Volunteers
- 74 people
- Sponsor
- Aristotle University Of Thessaloniki
Parkinson's Disease, Deep Brain Stimulation
Predicting Cognition After DBS for Parkinson's Disease
The aim of the study is to improve estimation of cognitive outcome after STN-DBS in PD in order to avoid risk factors by optimizing peri- and intraoperative management personalize therapeutic strategies for optimal long-term…
- Conditions
- Parkinson's Disease, Deep Brain Stimulation, Postoperativeneurocognitive Deficit, Postoperative Delirium
- Trial name
- NCT03982953
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Charite University, Berlin, Germany
Short Bowel Syndrome
Open-Label Pilot Study With Crofelemer in Patients With Short Bowel Syndrome
The objectives of this study are to evaluate the efficacy and safety of crofelemer treatment in adults affected by Short Bowel Syndrome (SBS) with an ileostomy on parenteral support (PS) in reducing output or PS needs.
- Trial name
- NCT06326645
- Testing
- Crofelemer Oral Product
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Jessica Sosio
Rotator Cuff Tear Arthropathy, Post Operative Pain
Effect of Radiofrequency of Suprascapular Nerve in Shoulder Reverse Arthroplasty
The purpuse of this study is to asses if the pulsed radiofrecuency of the supraescapular nerve and accesory nerve have the same or superior efectivity controlling the acute postoperative pain than interscalenic braquial plexus…
- Trial name
- NCT05785572
- Testing
- supraescapular nerve radiofrequency, interescalenic braquial plexus
- Where
- Spain
- Volunteers
- 54 people
- Sponsor
- Hospital Universitario Virgen Macarena
Cardiac Valve Disease, Coronary Artery Disease
Telehealth Interventions for Cardiac Surgery
The goal of this clinical trial is to compare telehealth monitoring at home against usual care in patients undergoing planned heart surgery. The main questions it aims to answer are: 1.
- Conditions
- Cardiac Valve Disease, Coronary Artery Disease, Surgical Complication
- Trial name
- TICS (NCT05621954)
- Testing
- Telehealth Monitoring
- Where
- United Kingdom
- Volunteers
- 318 people
- Sponsor
- Liverpool Heart and Chest Hospital NHS Foundation Trust
Postoperative Pain
Regional Anesthesia in THR - Comparing the Analgesic Efficacy of Fascia Iliaca Block and Erector Spinae Plane Block
THR (Total Hip Replacement) can be very painful and regional anesthesia is very effective in reducing postoperative pain. Fascia Iliaca Block (FIB) and Erector Spinae Plane Block (ESPB) are indirect approaches to the lumbar…
- Trial name
- PTA-ALR (NCT04574154)
- Testing
- FIB, ESPB, spinal anesthesia
- Where
- Italy
- Volunteers
- 64 people
- Sponsor
- Papa Giovanni XXIII Hospital
Postoperative Nausea and Vomiting
Prevention of Postoperative Nausea and Vomiting (PONV) in Surgical Patients
This study will compare two different drug regimens (oral dronabinol versus intravenous ondanseteron) for the prevention of post-operative nausea and vomiting (PONV).
- Trial name
- PONV (NCT00757822)
- Testing
- Dronabinol, Ondansetron
- Where
- United States
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Respiratory, Postoperative Pain
The Effect of Pranayama on Pain and Respiration After Coronary Bypass Surgery
After CABG surgery, patients tend to breathe superficially because they experience pain while breathing. By restricting deep inspiration and cough; There is a decrease in lung tidal volume, vital capacity, and functional residual…
- Conditions
- Respiratory, Postoperative Pain, Nursing
- Trial name
- NCT06485531
- Testing
- Pranamaya, Pursed Lips Breathing
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Post-operative Pain
Post-operative Oral Morphine Versus Ibuprofen
Children 5-17 years of age who have undergo orthopedic day surgical procedures for definitive management of fractures, tendon release, etc.
- Trial name
- NCT01686802
- Testing
- oral morphine, Ibuprofen
- Where
- Canada
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Breast Neoplasms, Mastectomy
Impact of Erector Spinae Plane Block on Chronic Postsurgical Pain in Breast Cancer Patients
Chronic postsurgical pain (CPSP) has an incidence of 46% in patients after breast cancer surgery, which seriously affects patients' physiological and psychological function, as well as quality of life.
- Conditions
- Breast Neoplasms, Mastectomy, Nerve Block, Dexmedetomidine
- Trial name
- NCT05494502
- Testing
- Erector spinae plane block, Control group
- Where
- 2 sites in China
- Volunteers
- 1,206 people
- Sponsor
- Peking University First Hospital
Postoperative Pain, Acute, Regional Anesthesia
Comparation of Bilateral and Unilateral Erector Spinae Plane Block
Although laparoscopic cholecystectomy is a minimally invasive surgery with many advantages, it is one of the operations with high postoperative pain scores. Opioids are frequently used to prevent postoperative pain.
- Conditions
- Postoperative Pain, Acute, Regional Anesthesia, Multimodal Analgesia
- Trial name
- NCT05152602
- Testing
- Bilateral Erector spinae plane block, Unilateral Erector spinae plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Ankara City Hospital Bilkent
Irriversible Pulpitis
Analyzing the Impact of Occlusal Reduction on the Pain Following Root Canal Therapy in Molar Teeth With and Without Pain in Turkish Patients.
Introduction: This study aimed to compare the intensity of postoperative pain after single-visit root canal treatment of symptomatic or asymptomatic teeth following occlusal reduction.
- Trial name
- NCT06953856
- Testing
- occlusal reduction
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Pain, Postoperative
PENG vs. Femoral Nerve Block for Pain Control in Hip Surgery
The aim of this study is to compare the efficacy of the ultrasound- guided pericapsular nerve group (PENG) block versus the femoral nerve block (FNB) for postoperative pain control in patients undergoing hip surgeries…
- Trial name
- NCT07597551
- Testing
- PENG BLOCK, Femoral nerve block
- Volunteers
- 100 people
- Sponsor
- Benha University
Solid Organ Transplant Complications
Microbiota Transplantation in Solid Organ Transplantation
Solid organ transplantation (SOT), an alternative therapy for end-stage diseases, offers increased longevity and better quantity of life.
- Trial name
- NCT06730451
- Testing
- Washed Microbiota Transplantation
- Where
- China
- Volunteers
- 50 people
- Sponsor
- The Second Hospital of Nanjing Medical University
Surgical Site Infection
Prophylactic Effects for Preventing Surgical Site Infection in Third Molar Surgery
The purpose of this study is to determine the incidence of surgical site infection (SSIs) after third molar surgery for different duration of intravenous ampicillin administration.
- Trial name
- NCT06368102
- Testing
- Ampicillin
- Where
- Japan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Uji Takeda Hospital
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