Clinical trials: Complications, Postoperative
Multimodal Analgesia, Tramadol
Tramadol Versus Morphine for Postoperative Pain Relief Following Laparoscopic Abdominal Surgery
Tramadol is commonly used postoperatively due to its ease of administration, but it carries several risks, including interindividual variability, drug interactions, neuropsychiatric risks in elderly patients, and long-term…
- Conditions
- Multimodal Analgesia, Tramadol, Enhanced Recovery After Surgery, Opioid and Postoperative Pain
- Trial name
- TRAMORNOT (NCT07914335)
- Testing
- Anesthesia induction, Anesthesia maintenance, Multimodal analgesia
- Where
- France
- Volunteers
- 140 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Non-restorable Teeth, Intraoral Surgical Incisions
Efficacy of Using Knotless Barbed Suture vs N-Butyl Cyanoacrylate Glue Tissue Adhesive for Closure of Intraoral Surgical Incisions
This clinical study aims to compare the efficacy of knotless barbed sutures versus N-butyl cyanoacrylate glue tissue adhesive for the closure of intra-oral surgical incisions, with traditional PGA vicryl sutures as a control…
- Conditions
- Non-restorable Teeth, Intraoral Surgical Incisions, Wound Closure, Surgical Tooth Extraction
- Trial name
- KBA vs CA (NCT07491276)
- Testing
- PDO Knotless Barbed Suture, N-Butyl Cyanoacrylate Glue (PERIACRYL), 3/0 Resorbable PGA Suture
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Future University in Egypt
Gastric Cancer
Postoperative Enteral Immunonutrition in Gastric Cancer
Immunomodulating enteral nutrition in the perioperative period may reduce postoperative complications in cancer patients. Little is known if this effect translates to the better survival.
- Trial name
- NCT02647476
- Testing
- Immunomodulating nutrition (Reconvan), Standard nutrition (Peptisorb)
- Where
- Poland
- Volunteers
- 98 people
- Sponsor
- Jagiellonian University
Pain, Postoperative, Analgesia
Ultrasound-Guided Bilateral Transversalis Fascia Plane Block With vs Without Dexamethasone for Cesarean Delivery
Cesarean delivery is one of the most frequently performed surgical procedures worldwide, and effective postoperative pain management is essential to facilitate early mobilization, maternal-infant bonding, breastfeeding, and…
- Trial name
- NCT07736989
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Bahçeşehir University
Pain, Postoperative
Comparison of Post-operative Pain Frequency
The objective of this study is: To compare the post-operative pain frequency after single visit root canal versus multiple visit root canal treatment in patients with non-vital teeth Post-operative pain is less frequent after…
- Trial name
- NCT04944589
- Testing
- ROOT CANAL TREATMENT
- Where
- Pakistan
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- Fatima Memorial Hospital
Postoperative Complications, Cost-Benefit Analysis
Advanced Recovery Room Care II - Improved Recovery After Surgery
Moderate-risk surgical patients have a very high incidence of early serious postoperative complications (approximately 50% at Royal Adelaide Hospital, RAH).
- Trial name
- ARRCII (NCT04769518)
- Testing
- Advanced Recovery Room Care (ARRC)
- Where
- Australia
- Volunteers
- 857 people
- Sponsor
- University of Adelaide
Pain, Postoperative
Thoracic Paravertebral Block Using Ropivacaine and Dexmedetomidine
The hypothesis of the study is whether dexmedetomidine plus local anesthetic ropivacaine could extend the pain relieve time compared with only ropivacaine when thoracic paravertebral block is performed at the end of…
- Trial name
- NCT02814890
- Testing
- Video-assisted Pneumonectomy, Thoracic paravertebral block
- Where
- China
- Volunteers
- 65 people
- Sponsor
- Jianghui Xu
Blood Loss, Surgical
Efficacy of Tranexamic Acid in Preventing Post Operative Blood Loss in Bone Sarcoma Patient
investigator will see the efficacy of tranexamic acid in limb salvage surgery patients which will prevent blood loss and help in conservation of blood products.
- Trial name
- NCT05427513
- Testing
- Tranexamic acid injection, normal saline
- Where
- Pakistan
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Shaukat Khanum Memorial Cancer Hospital & Research Centre
Pain, Postoperative
Reducing Opioid Use and Misuse After Wisdom Molar Extractions
Reducing opioid prescription related use and misuse is a major focus for countering the national epidemic of opioid overdose and death.
- Trial name
- NCT04414917
- Testing
- Twin block, iPill dispenser
- Where
- United States
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Pain, Postoperative, Postoperative Nausea and Vomiting
Effect of Pulmonary Recruitment Maneuver (PRM) on Pain and Nausea After Laparoscopic Cholecystectomy
This prospective, blinded, randomized clinical trial investigates the effect on postoperative pain and nausea, when performing a ventilator-piloted PRM at the end of a laparoscopic cholecystectomy.
- Trial name
- NCT03026543
- Testing
- Pulmonary Recruitment Maneuver, Laparoscopic cholecystectomy, Ventilator
- Where
- Sweden
- Volunteers
- 260 people
- Sponsor
- Region Östergötland
Epithelial Ovarian Cancer
Postoperative Adjuvant Chemotherapy With Bevacizumab and Maintenance Bevacizumab After Neoadjuvant Chemotherapy for Ovarian Cancer
This study is to determine the feasibility of postoperative platinum-based chemotherapy plus adjuvant and maintenance bevacizumab after neoadjuvant chemotherapy followed by interval surgery in patients with extensive stage IIIC…
- Trial name
- NCT02022917
- Testing
- Bevacizumab
- Where
- 5 sites in Taiwan
- Volunteers
- 22 people
- Sponsor
- Chang Gung Memorial Hospital
Postoperative Atelectasis, Postoperative Pulmonary Complications
HFNC for Postoperative Atelectasis After Laparoscopic Surgery
Pneumoperitoneum and Trendelenburg positioning during laparoscopic surgery promote atelectasis development, which has been reported in up to 90% of patients under general anesthesia and increases the risk of postoperative…
- Trial name
- NCT07676760
- Testing
- High-Flow Nasal Cannula (HFNC), Conventional Oxygen Therapy
- Volunteers
- 90 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Anastomotic Leak
Role of Procalcitonin, C-Reactive Protein, and WBC Count in Prediction of Colorectal Anastomotic Leak
The interest in identifying a biological marker for the early detection of AL is growing. Such a marker could play a vital role in modern fast-track multimodal protocols, allowing safe and early discharge of patients after…
- Trial name
- NCT05159024
- Testing
- CRP, PCT, and WBCs trajectories
- Where
- Egypt
- Volunteers
- 205 people
- Sponsor
- Suez Canal University
Postoperative Pain, Pediatric Open Heart Surgery
A Combination of Intrathecal Fentanyl and Pecto-Intercostal Fascial Block in Paediatric Cardiac Surgery.
Cardiac surgery is commonly performed via median sternotomy. Patients undergoing cardiac surgical procedures frequently experience intense acute pain in the post-sternotomy wound, which can potentially transition into persistent…
- Trial name
- NCT06882655
- Testing
- PIFB group, Intrathecal fentanyl(IT fentanyl), IT + PIFB
- Where
- 2 sites in Egypt
- Volunteers
- 90 people
- Sponsor
- Alexandria University
Puerperal Infection
Effect of Vaginal Douching With Betadine Before CS for Prevention of Post Operative Infections
The present study was a prospective randomized controlled trial in which subjects received a vaginal preparation with povidone-iodine solution immediately prior to caesarean delivery or received no vaginal preparation
- Trial name
- NCT03397615
- Testing
- Betadine douches
- Where
- Egypt
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Cairo University
Breast Edema, Breast Cancer Related Lymphoedema
Effectiveness of Kinesio Taping in Patients With Chronic Breast and/or Truncal Oedema After Treatment for Breast Cancer.
The goal of the KiTaLymph trial is to investigate whether the application of kinesio tape is effective in women with persistent (>6 months) breast and/or truncal oedema after treatment for breast cancer.
- Conditions
- Breast Edema, Breast Cancer Related Lymphoedema, Breast Cancer Related Lymphedema, Truncal Lymphedema
- Trial name
- KiTaLymph (NCT07080476)
- Testing
- Decongestive lymphatic therapy, Kinesio tape, Compression bra (sub-study)
- Where
- 4 sites in Belgium
- Volunteers
- 128 people
- Sponsor
- Universiteit Antwerpen
Postoperative Pain
Effects of Regional Anesthesia Following Mastectomy
Patients of breast surgery dated between April 2016 and March 2021 will be scanned in three groups; solely induced general anesthesia, general anesthesia induced with Erector Spinae Plane Block, and general anesthesia induced…
- Trial name
- NCT05276440
- Volunteers
- 182 people
- Sponsor
- Koc University Hospital
Cervix Cancer, Radiotherapy, Adjuvant
Postoperative Hypofractionated Intensity-modulated Radiation Therapy with Concurrent Chemotherapy in Cervical Cancer
To investigate the acute toxicities, late toxicities, and treatment results when the early cervical cancer patients are treated by concurrent chemotherapy with hypofractionated intensity-modulated radiotherapy (2.5 Gy X 16…
- Conditions
- Cervix Cancer, Radiotherapy, Adjuvant, Radiotherapy, Intensity-Modulated, Hypofractionated Dose
- Trial name
- NCT03239613
- Testing
- POHIM-CCRT
- Where
- South Korea
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Myocardial Ischemic Reperfusion Injury
Myocardial Protection and Anesthetic Agents
The aim of this study was to investigate the myocardial protective effects of remifentanil and dexmedetomidine in cardiac surgery.
- Trial name
- NCT02405689
- Testing
- Remifentanil, Dexmedetomidine, Sevoflurane
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Cukurova University
Liver Transplant Disorder, Reperfusion Injury
Cardiac Strain Using Speckle Tracking Echocardiography During Orthotopic Liver Transplantation
Researchers are trying to improve the understanding of systolic function of the heart at the time of liver reperfusion in patients undergoing orthotopic liver transplantation.
- Trial name
- NCT04316468
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
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