Clinical trials: Complications, Postoperative
Incisional Hernia, Large Incisional Hernia
Retrospective Analysis on Large Incisional Hernia in High Risk Patients
Large incisional hernia (LIH) is a challenging condition where the abdominal wall is hopelessly compromised. Nowadays the best treatment option in this particularly frail subset of patients is a major issue.
- Trial name
- NCT04801394
- Testing
- hernioplastic and insertion of FLaPp® composite mesh
- Volunteers
- 43 people
- Sponsor
- University of Campania Luigi Vanvitelli
Postoperative Pain
Compare Intraperitoneal Instillation of Bupivacaine+dexmedetomidine Versus Bupivacaine+dexamethasone on Postoperative Pain After Lap Cholecystectomy
Comparison of intraperitoneal instillation of bupivacaine with dexmedetomidine versus bupivacaine with dexamethasone on postoperative pain after laparoscopic cholecystectomy
- Trial name
- NCT06535256
- Testing
- bupivacaine with dexamethasone, bupivacaine with dexmedetomidine
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aswan University Hospital
Chronic Postsurgical Pain, Chronic Opioid Users
Prevention of Chronic Postsurgical Pain in Chronic Opioid Users:
Chronic opioid users undergoing surgery are at increased risk of CPSP, contributing to long-term disability, decreased quality of life, and prolonged opioid exposure.
- Conditions
- Chronic Postsurgical Pain, Chronic Opioid Users, Transitional Pain Service, Postoperative Pain
- Trial name
- PRE-OPIOID (NCT07717151)
- Testing
- standard institutional perioperative management, specialized teleconsultation
- Where
- France
- Volunteers
- 354 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Surgical Wound Infection
Preoperative Bath in Patients Submitted to Hip Arthroplasty
Clinical trial for prevention, randomized, controlled, blinded, parallel, with three arms which purpose is verify the effects of nursing intervention preoperative bathing with 4% chlorhexidine gluconate, 10% Povidone iodine…
- Trial name
- NCT03001102
- Testing
- 4% Chlorhexidine gluconate, 10% PVPI degermante, Soap without antiseptic
- Where
- Brazil
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Quality of Life, Pain, Postoperative
Quality of Recovery After General or Spinal Anesthesia for Inguinal Hernia Repair
Different anesthetic techniques have been proposed for carrying out Inguinal hernia repair, including local anesthesia, regional and general.
- Conditions
- Quality of Life, Pain, Postoperative, Personal Satisfaction, Postoperative Complication
- Trial name
- NCT02696122
- Testing
- Local Group, Spinal anesthesia
- Where
- Brazil
- Volunteers
- 70 people
- Sponsor
- Pontificia Universidade Catolica de Sao Paulo
Delirium - Postoperative
The Effect of Aromatherapy on Delirium in Critically Elderly Patients Undergoing Fracture Surgery
The aim of this quasi-experimental study was to examine the effect of lavender aromatherapy on delirium in patients who underwent fracture surgery, were in intensive care, and were over 60 years old.
- Trial name
- NCT06772129
- Testing
- Aromatherapy
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Senay Gokdemir
Pain Management, Hemorrhoids Third Degree
Topical Lidocaine 23%/Tetracaine 7% Ointment for Post-Hemorrhoidectomy Analgesia: A Randomized Controlled Trial
The goal of this clinical trial is to learn if a topical ointment containing two local anesthetics (lidocaine 23% and tetracaine 7%) can reduce pain after hemorrhoid surgery in adults.
- Conditions
- Pain Management, Hemorrhoids Third Degree, Hemorrhoids Fourth Degree, Hemorrhoids Second Degree
- Trial name
- NCT07688031
- Testing
- Lidocaine 23% / Tetracaine 7% topical ointment (compounded)
- Where
- Chile
- Volunteers
- 74 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Postoperative Pain
RCT to Test Regional Anesthesia Effect on Decreased Opiate Use
Examining use of strong pain medication with the use of perioperative anesthetic medications vs no use of the same perioperative medication
- Trial name
- NCT06989866
- Testing
- Bupivacaine
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, Portsmouth
Postoperative Pulmonary Complications (PPCs), One-lung Ventilation (OLV)
Individualized Open Lung Ventilation and Postoperative Pulmonary Complications in Thoracic Surgery
This prospective, single-center, randomized controlled trial aims to evaluate the efficacy of an intraoperative "Individualized Open Lung Ventilation" strategy compared to a standard lung-protective ventilation strategy in…
- Conditions
- Postoperative Pulmonary Complications (PPCs), One-lung Ventilation (OLV), Thoracic Surgery, Video Assisted
- Trial name
- NCT07387822
- Testing
- Standard Lung-Protective Ventilation, Individualized Open Lung Ventilation
- Where
- China
- Volunteers
- 352 people
- Sponsor
- Aerospace Center Hospital
Laparotomy, Laparotomy Surgery
Saudi Emergency Laparotomy Audit
The Saudi Emergency Laparotomy Audit (SELA) is a national, multicenter observational clinical audit designed to evaluate outcomes and quality of care for patients undergoing emergency laparotomy in Saudi Arabia.
- Conditions
- Laparotomy, Laparotomy Surgery, Emergency Treatment, Abdominal Diseases
- Trial name
- SELA (NCT07429929)
- Testing
- Emergency Laparotomy
- Where
- Saudi Arabia
- Volunteers
- 10,000 people
- Sponsor
- King Faisal Specialist Hospital & Research Center
Pain, Nausea
Evaluation of the Effect of the LI4 Cold Application
It is an experimental study conducted to evaluate the effectiveness of cold application to the LI4 point of the hand to reduce/eliminate pain, nausea and anxiety in postoperative patients.
- Conditions
- Pain, Nausea, Anxiety
- Trial name
- LI4 (NCT06357429)
- Testing
- Cold Application
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Saglik Bilimleri Universitesi
Pain, Postoperative, Apical Periodontitis
FE in Anterior Teeth
The purpose of this study is to determine whether enlarging the apical foramen causes postoperative pain in maxillary anterior teeth with apical periodontitis.
- Trial name
- NCT03527602
- Testing
- Foraminal enlargement
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Isparta Military Hospital
Opioid Use, Cytokine
Cranial Electrotherapy Stimulation on Anesthetics Consumption and Postoperative Pain
Cranial electrotherapy stimulation (CES) is a non-invasive intervention to treat anxiety, depression, insomnia, and pain. But clinical studies and applications of CES in relation to acute postoperative pain are few.
- Trial name
- NCT03825471
- Testing
- electrotherapy, Opioid Anesthetics, colon cancer surgery
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Cesarean Section Complications, Postpartum Hemorrhage
The Comparison of the Effect of Different Oxytocin Administrations on the Blood Loss During Cesarean Delivery
This study compares the effect of starting intravenous oxytocin infusion early before uterine incision versus late after umbilical cord clamping on the blood loss during elective cesarean section
- Conditions
- Cesarean Section Complications, Postpartum Hemorrhage, Blood Loss, Surgical, Blood Loss, Postoperative
- Trial name
- NCT03967171
- Testing
- before uterine incision oxytocin, after clamping the umbilical cord oxytocin
- Where
- Turkey (Türkiye)
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Postoperative Recovery, PONV
Comparison of the Effects of Moderate- and High-Dose Glucocorticoids on Postoperative Recovery
Laparoscopic cholecystectomy is a commonly performed minimally invasive surgical procedure; however, postoperative pain, nausea, and delayed recovery remain clinically relevant problems.
- Trial name
- NCT07469332
- Testing
- Saline (0.9% NaCl), TAP Block, moderate dose Dexamethasone
- Where
- Turkey (Türkiye)
- Volunteers
- 135 people
- Sponsor
- Ankara City Hospital Bilkent
Decision Support System, Outcome
Assisted Fluid Management (AFM) System and Postoperative Outcome After High-risk Abdominal Surgery
Goal directed fluid therapy (GDFT) or "Personalized fluid therapy" may benefit high-risk surgical patients but these strategies are infrequently implemented.
- Trial name
- PEFLA (NCT06011187)
- Testing
- Routine care, AFM
- Where
- 17 sites in United States, Belgium and 3 more
- Volunteers
- 2,007 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Chronic Pain, Post Stroke Pain
Closed-loop Deep Brain Stimulation to Treat Refractory Neuropathic Pain
Deep brain stimulation (DBS) holds promise as a new option for patients suffering from treatment-resistant chronic pain, but current technology is unable to reliably achieve long-term pain symptom relief.
- Conditions
- Chronic Pain, Post Stroke Pain, Phantom Limb Pain, Spinal Cord Injuries
- Trial name
- NCT03029884
- Testing
- Open-Loop DBS, Closed-Loop DBS
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Prasad Shirvalkar, MD, PhD
Postoperative Pain, Opioid Use
Dexmedetomidine Use in SZMN Blocks for Pediatric T&A Pain Control
The suprazygomatic maxillary nerve (SZMN) block is a well-established, safe and effective regional technique for pain management following cleft palate procedures.
- Trial name
- NCT05208892
- Testing
- SZMN block, SZMN block with Dexmedetomidine
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Stanford University
Post-operative Pain, Sinus Surgery
Postoperative Pain Control in Septum and Sinus Surgery
This study will evaluate if the use of acetaminophen round the clock (scheduled doses) will lead to less opiate use in the first week post-operative (after surgery) in sinus/septum surgery patients.
- Trial name
- NCT04149964
- Testing
- Acetaminophen 325 mg Oral Tablet, Acetaminophen 650 mg Oral Tablet, OxyCODONE 5 mg Oral Tablet
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Corewell Health East
Pancreaticoduodenectomy, Postoperative Pancreatic Fistula
Pancreatic Parenchymal Injection of N-butyl-2-cyanoacrylate
This randomized controlled trial investigates the safety and efficacy of injecting N-butyl-2- cyanoacrylate (Histoacryl®) into the pancreatic parenchyma during pancreaticoduodenectomy (PD) to enhance the security of the…
- Conditions
- Pancreaticoduodenectomy, Postoperative Pancreatic Fistula, Pancreas Cancer, Periampullary Cancer
- Trial name
- NBCA (NCT07230509)
- Testing
- Pancreatic parenchymal injection of N-butyl-2- cyanoacrylate(Histoacryl®)Injection Group., Standard Pancreaticojejunostomy
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Minia University
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