Clinical trials: Complications, Postoperative
Pain, Postoperative
Opioids Following ACL
The purpose of this study is to evaluate the effectiveness of a post-operative opioid pain 18 management protocol for anterior cruciate ligament reconstruction (ACLR).
- Trial name
- NCT04278703
- Testing
- Oxycodone
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- Rothman Institute Orthopaedics
Rectal Cancer, Rectal Neoplasms
The Role of Transanal Tube Drainage as A Mean of Prevention of Anastomotic Leakage Anastomotic Leakage
Anastomotic leakage (AL) is considered the commonest major complication after surgery for rectal cancer. Transanal tube drainage role in the prevention of AL is still debatable.
- Conditions
- Rectal Cancer, Rectal Neoplasms, Anastomotic Leak
- Trial name
- NCT03325361
- Testing
- Tube drain insertion
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Rome Tor Vergata
Coagulation, Blood, Compression Devices, Intermittent Pneumatic
Alterations of Blood Clotting With the Use of Sequential Compression Devices on the Lower Limbs
This study aims to assess possible alteration in coagulation (blood clotting) following treatment with sequential compression devices (SCD) plus low-molecular weight heparin (LMWH) as opposed to LMWH alone.
- Conditions
- Coagulation, Blood, Compression Devices, Intermittent Pneumatic, Postoperative Complications, Thrombelastography
- Trial name
- TEGLeg (NCT00726570)
- Testing
- Sequential compression device therapy, Dalteparin, TEG
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Parma
Adolescent Idiopathic Scoliosis, Respiratory Depression
Anesthetic Optimization in Scoliosis Surgery
The standard anesthetic care plan for people having adolescent idiopathic scoliosis surgery will be accompanied by a pharmacokinetic simulation of the administered drugs to suggest opportunities to adjust drug doses to achieve…
- Conditions
- Adolescent Idiopathic Scoliosis, Respiratory Depression, Postoperative Pain
- Trial name
- AIS (NCT02481570)
- Testing
- pharmacokinetic simulation
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Florida
Laminectomy, Post-laminectomy Syndrome
Spinal Cord Stimulation in Patients With Post-Laminectomy Syndrome in Testing Phase
Traditionally, pain relief through spinal cord stimulation has been associated with the appearance of paresthesia in the affected area.
- Conditions
- Laminectomy, Post-laminectomy Syndrome, Spinal Cord Syndrome, Failed Back Surgery Syndrome
- Trial name
- NCT03702010
- Testing
- spinal cord stimulation conventional, spinal cord stimulation experimental
- Where
- 2 sites in Spain
- Volunteers
- 27 people
- Sponsor
- Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León
Pain, Postoperative, Adult
Longitudinal Assessment of Pain-Related Patient-Reported Outcomes After Surgery
Little is known about pain-related outcomes experienced by patients in the first few weeks after surgery, once they are discharged from hospital.
- Conditions
- Pain, Postoperative, Adult, Pain Measurement, Functional Status
- Trial name
- NCT05315596
- Where
- 16 sites in Germany, Mexico
- Volunteers
- 1,000 people
- Sponsor
- Jena University Hospital
Lumbar Disc Disease, Epidural Fibrosis
The Effect of Mediclore as an Anti-adhesion Agent and Safety in Full-endoscopic Spine Surgery: a Preliminary Study
The goal of this clinical trial is to compare efficacy and safety of Mediclore as anti-adhesion agent in patient who undergo endoscopic lumbar discectomy.
- Conditions
- Lumbar Disc Disease, Epidural Fibrosis, Failed Back Surgery Syndrome
- Trial name
- NCT06034041
- Testing
- Mediclore, Normal Saline
- Where
- Thailand
- Volunteers
- 78 people
- Sponsor
- King Chulalongkorn Memorial Hospital
Emergence Agitation
Effects of Preoperative Child and Parental Anxiety on Emergence Agitation
Investigation of the effect of preoperative parental anxiety and sociodemographic characteristics on emergence agitation in patients undergoing pediatric adenotonsil surgery
- Trial name
- NCT07486427
- Testing
- No intervention - observational study
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people
- Sponsor
- Ondokuz Mayıs University
Surgical Site Infection
Checklist to Prevent MRSA Surgical Site Infections
The goals of this project are 1) to assess the effectiveness and cost-effectiveness of the checklist to prevent MRSA SSIs among Veterans undergoing TJA or cardiac surgery, and 2) to assess barriers and facilitators to checklist…
- Trial name
- NCT02216227
- Testing
- Mupirocin, Chlorhexidine gluconate, Cefazolin
- Where
- 11 sites in United States
- Volunteers
- 23,005 people
- Sponsor
- VA Office of Research and Development
Ischemia Reperfusion Injury
Protecting Autologous Free Flaps From Ischemia/Reperfusion Damage With Cold Storage.
Reconstructive microsurgery allows autologous transplantation of flaps. The procedure causes temporary ischemia. The absence of perfusion and the post-anastomosis reperfusion causes ischemia/reperfusion (I/R) damage and an…
- Trial name
- PAFFIRD (NCT06523920)
- Testing
- University of Wisconsin solution + cold storage, Unperfused free flap under warm ischemia
- Volunteers
- 90 people
- Sponsor
- University of Cagliari
Cholecystitis, Acute
Effectiveness of Empirical Antibiotic Use in Mild to Moderate Acute Inflammatory Gallbladder Disease
This clinical trial is an exploratory clinical trial that evaluates the necessity and effectiveness of empirical antibiotic use in mild and moderate acute inflammatory gallbladder diseases that require surgery, and the incidence…
- Trial name
- NCT05339282
- Testing
- Laparoscopic cholecystectomy
- Where
- South Korea
- Volunteers
- 370 people
- Sponsor
- Seoul St. Mary's Hospital
Breast Cancer
Use of Clorhexidine Dressings to Reduce Surgical Site Infections in Breast Cancer Surgery. A Controlled Clinical Trial
Surgical site infection (SSI) after breast and axillary surgery occurs more often than for other clean surgical procedures. Infection in the setting of sick woman could delay the adjuvant therapy and result increase morbidity and…
- Trial name
- NCT03229824
- Testing
- Antiseptic occlusive dressing group
- Where
- Mexico
- Volunteers
- 116 people
- Sponsor
- National Institute of Cancerología
Pain, Postoperative, Arthroplasty Complications
Intraoperative Ketamine for Patients Undergoing Total Joint Arthroplasty
Prospective randomized double blinded, placebo controlled study that will evaluate the effect of intra-operative ketamine administration on post-operative analgesic requirements and self-reported pain in patients undergoing total…
- Trial name
- NCT04437888
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Short Bowel Syndrome, Intestinal Failure
Infant & Toddler Short Gut Feeding Outcomes Study
The purpose of this study is to better understand why children with short gut develop feeding problems.
- Conditions
- Short Bowel Syndrome, Intestinal Failure, Home Parenteral Nutrition
- Trial name
- NCT01946503
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Los Angeles
Wound Breakdown, Breast Reduction
CO2Lift and T-Junction Breakdown Rates Evaluation After Breast Reduction Surgery Pilot Trial
The goal of this pilot study is to determine the feasibility of a larger randomized controlled trial evaluating CO₂Lift® Pro Carboxy Gel to reduce wound breakdown after bilateral breast reduction in adult female patients…
- Conditions
- Wound Breakdown, Breast Reduction, Surgical Wound, Breast Surgery
- Trial name
- CO2-BREAST (NCT07408960)
- Testing
- Carboxygel, Vaseline
- Volunteers
- 10 people
- Sponsor
- University of Calgary
Postoperative Pain
Comparing Two Root Canal Cleaning Solutions (Chlorhexidine vs. Sodium Hypochlorite) for Pain After Treatment
Brief Summary (A short description for the lay public) This study aims to find out if the type of cleaning solution used during a root canal affects the pain a patient feels the next day.
- Trial name
- CHXvsNaOCl-Pai (NCT07453160)
- Testing
- Chlorhexidine gluconate 2%, Sodium hypochlorite 5.25%
- Volunteers
- 90 people
- Sponsor
- College of Physicians and Surgeons Pakistan
Pain, Postoperative, Opioid Use
Therapeutic Efficacy of Intravenous Lidocaine Infusion Compared With Epidural Analgesia for Postoperative Pain Control in Adult Patients Undergoing Major Abdominal Surgery: Non-Inferiority Clinical Trial
Major abdominal surgery continues is one of the most performed surgical procedures in the world, both electively and urgently. One of the main problems of this type of intervention is postoperative pain.
- Trial name
- NCT04017013
- Testing
- Epidural Analgesia, Lidocaine Infusion
- Where
- Colombia
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Universidad de Antioquia
Esophageal Neoplasm
Lung Ultrasound in the Early Detection of Postoperative Pulmonary Complications After Esophagectomy
The perioperative management of esophageal cancer has evolved considerably in recent years. Over the last 30 years, postoperative mortality has been steadily decreasing. However, respiratory morbidity remains high (30-40%).
- Trial name
- OESOLUS (NCT05453760)
- Where
- France
- Volunteers
- 274 people
- Sponsor
- University Hospital, Lille
Postoperative Pain
Acupuncture for Postoperative Pain After Abdominal Surgery for Gynecological Diseases
Objectives: To examine the efficacy and safety of electroacupuncture (EA) combined with auricular acupuncture (AA) in reducing post-operative pain in patients following abdominal surgery for gynecological diseases.
- Trial name
- NCT02851186
- Testing
- Acupuncture
- Where
- 2 sites in Hong Kong
- Volunteers
- 72 people
- Sponsor
- The University of Hong Kong
Postoperative Complications, Postoperative Delirium
Acupoint Stimulation Improve Postoperative Delirium in Elderly Patients
Postoperative delirium is with increased incidence in elderly patients. Previous studies have shown that acupuncture related techniques could induce protection against brain ischemia and improve outcome after cerebral diseases.
- Trial name
- AICE (NCT03726073)
- Testing
- Transcutaneous acupoint electrical acupoint stimulation(TEAS) and auricular acupressure, Usual care
- Where
- China
- Volunteers
- 210 people
- Sponsor
- Air Force Military Medical University, China
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