Clinical trials: Complications, Postoperative
Surgery, Trauma to the Abdomen
Non Invasive Ventilation in Abdominal Postoperative Period
Acute respiratory failure may occur early in the postoperative course, requiring endotracheal intubation and mechanical ventilation in selected patients, thus increasing morbidity and mortality and prolonging intensive care unit…
- Conditions
- Surgery, Trauma to the Abdomen, Acute Respiratory Failure
- Trial name
- NIVAS (NCT01971892)
- Testing
- Non Invasive ventilation (facial mask and NIV ventilator), Standard oxygen therapy with facial mask
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Montpellier
Postoperative Cognitive Dysfunction, Depressive Symptoms
Perioperative Cognitive Trajectories in Deferred Surgery (CoTELE-SURGE)
Cognition is the way people use their brains to think, understand, remember and make decisions. Cognitive changes are often seen even up to 1 year after surgery.
- Conditions
- Postoperative Cognitive Dysfunction, Depressive Symptoms, Postoperative Pain
- Trial name
- CoTELE-SURGE (NCT04787536)
- Testing
- Non-cardiac surgery
- Where
- Canada
- Volunteers
- 300 people
- Sponsor
- McMaster University
Cerebral Small Vessel Disease, Postoperative Cognitive Function
VR Training to Improve Postoperative Cognitive Function in Elderly Patients With Cerebral Small Vessel Disease Undergoing Non-Cardiac Surgery
This clinical study aims to investigate whether virtual reality (VR)-based cognitive training can help improve postoperative cognitive function in elderly non-cardiac surgery patients with pre-existing cerebral small vessel…
- Trial name
- NCT07370844
- Testing
- Virtual reality cognitive function training, Virtual scene intervention
- Where
- 3 sites in China
- Volunteers
- 240 people
- Sponsor
- Peking University Third Hospital
Postoperative Pain, Postsurgical Pain
Comparison of the Postoperative Analgesic Efficacy of SAP and SPSIP Blocks in Patients Undergoing Mammoplasty
The aim is to compare the postoperative analgesic efficacy of serratus anterior plane block (SAPB) and serratus posterior superior intercostal plane block (SPSIPB) in patients undergoing mammoplasty surgery.
- Conditions
- Postoperative Pain, Postsurgical Pain, Breast Pain
- Trial name
- SPSIP (NCT07302399)
- Testing
- Serratus Anterior Plane Block, Serratus Posterior Superior Intercostal Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Chronic Pain
Comparison of the Efficacy of an Empowered Relief Single-Session Versus Standard Care for Reducing Postoperative Pain Following Elective Orthopedic Surgery: A Randomized Controlled Trial
The purpose of this study is to evaluate the efficacy and acceptability of the French-Canadian version of ER compared to standard care in reducing postoperative pain and improving recovery outcomes at 6-week and 3-month…
- Trial name
- ER-CHUS -Ortho (NCT07392099)
- Testing
- Empowered Relief (ER) consists of a single-session, 2-hour group class.
- Where
- Canada
- Volunteers
- 134 people
- Sponsor
- Université de Sherbrooke
Anxiety Postoperative, Surgery
Level of Anxiety in Patients Undergoing Invasive Foot Surgery
In recent decades, preoperative anxiety has been studied by numerous authors from different medical-surgical specialties, however, there are no studies in the scientific literature on anxiety prior to surgical procedures in the…
- Trial name
- NCT05948748
- Testing
- foot surgery
- Where
- Spain
- Volunteers
- 104 people
- Sponsor
- Universidad Católica de Ávila
Postoperative Pain
Analgesia in Knee Arthroscopic Surgery
Pain relief in knee Arthroscopic Surgery is essential for rapid recovery of function.
- Trial name
- NCT02818985
- Testing
- Dexamethasone, Dexmedetomidine, Saline
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Colorectal Surgery, Colorectal Cancer
Safety and Effectiveness Evaluation of the COLO-BT as an Alternative Treatment to the Ileostomy
The purpose of this study is to evaluate the Colorectal Balloon Tube (hereinafter referred to as COLO-BT™) device, a single use, temporary intraluminal bypass device, intended to reduce contact of fecal content with an…
- Conditions
- Colorectal Surgery, Colorectal Cancer, Rectal/Anal, Ileostomy - Stoma
- Trial name
- COLO-BT (NCT05826743)
- Testing
- COLO BT™, Stoma Creation
- Where
- 3 sites in United States
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- JSR Medical Co., Ltd.
Prostate Cancer, Men
Impact of Acetazolamide in Reducing Referred Postoperative Pain
Robotic assisted laparoscopic prostatectomy (RALP) is the standard treatment for prostate cancer, due to the benefits of decreased blood loss and length of stay.The procedure involves removing a man's prostate using a minimally…
- Trial name
- NCT04470843
- Testing
- Acetazolamide
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Medical College of Wisconsin
Nausea and Vomiting, Postoperative
Granisteron Versus Metoclopramide in Laparoscopic Cholecystectomy
Study aims at comparing the effect of granisteron with that of metoclopramide in patients undergoing lab cholecystectomy
- Trial name
- NCT04899817
- Testing
- Granisetron
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Gastroenterology, LARS - Low Anterior Resection Syndrome
A Randomised Clinical Investigation to Assess Efficacy of Low Volume Transanal Irrigation by Qufora® IrriSedo MiniGo Versus Conservative Treatment for Low Anterior Resection Syndrome Patients
The purpose of this post-market clinical follow up study is to assess the efficacy on clinical symptoms of LARS of low volume Transanal Irrigation by MiniGo in conjunction with conservative treatment versus conservative treatment…
- Conditions
- Gastroenterology, LARS - Low Anterior Resection Syndrome, Rectal Cancer
- Trial name
- MINIGO (NCT06923150)
- Where
- 9 sites in France
- Volunteers
- 78 people
- Sponsor
- Qufora A/S
Pain, Postoperative
Combined Nerve Blockade and Local Infiltration Anesthesia in Appendectomy - A Blinded Randomized Study
The purpose of this study is to assess whether the use of local anesthetic to numb the nerves that run deeper in the abdominal wall gives better post operative pain control than just infiltrating local anesthetic to the wound…
- Trial name
- NCT00508092
- Testing
- local anesthetic administration
- Where
- United Kingdom
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Royal Berkshire NHS Foundation Trust
Pain, Postoperative Pain
REduced Pain After Bariatric Surgery - Sleeve Gastrectomy
This study aims to analyze the effect of laparoscopic guided transversus abdominis plane (LG-TAP) block compared to placebo for postoperative analgesia following laparoscopic sleeve gastrectomy.
- Conditions
- Pain, Postoperative Pain, Acute Pain, Analgesia
- Trial name
- REPABS-SG (NCT06383234)
- Testing
- LG-TAP block with local anesthetic, LG-TAP block with saline solution, Port site infiltration
- Where
- Italy
- Volunteers
- 110 people
- Sponsor
- Fondazione Policlinico Universitario Campus Bio-Medico
Incomplete Reversal of Neuromuscular Block, Postoperative Respiratory Complications
Multi-center Study of Residual Neuromuscular Block Incidence in the Post-anesthesia Care Unit
Residual neuromuscular block (RNMB) is frequent in the immediate postoperative period and is a source of complications, mainly respiratory. The incidence is variable due to multiple factors. In Spain the incidence is unknown.
- Trial name
- ReCuSS (NCT02226809)
- Testing
- Accelerometry
- Where
- 25 sites in Spain
- Volunteers
- 763 people
- Sponsor
- University of Valencia
Ureteropelvic Junction Obstruction, Postoperative Pain
Ketamine Added to Quadratus Lumborum Block for Pain Relief After Infant Pyeloplasty
This prospective randomized study evaluates the effect of adding ketamine to bupivacaine in ultrasound-guided quadratus lumborum (QL) block for postoperative pain management in infants undergoing open pyeloplasty.
- Trial name
- KETA-QLB (NCT07596810)
- Testing
- Ketamine + Bupivacaine, Bupivacaine
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Alexandria University
Proctological Surgery
Interest in Clonidine in Association With Levobupivacaine Performing a Pudendal Block in Proctological Surgery.
Proctological surgery represents a short duration surgery performed in ambulatory, which causes significant post-operative pain.
- Trial name
- NCT04530903
- Testing
- Clonidine, Levobupivacaine, NaCl 0.9%
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Pain, Postoperative, Breast Cancer
Speeding Recovery From Pain and Opioid Use
Surgical treatment of breast cancer is associated with significant disability, and pain is often reported as a primary cause for declines in the ability to perform activities of daily living.
- Conditions
- Pain, Postoperative, Breast Cancer, Opioid Use, Surgery
- Trial name
- NCT03388814
- Testing
- Local infiltration of bupivacaine, Pectoralis Nerve block
- Sponsor
- Wake Forest University Health Sciences
Placenta Previa
ERAS Protocol for Cesarean Delivery in Women With Placenta Previa
This study aims to evaluate the impact of Enhanced Recovery After Surgery protocols on maternal outcomes patient satisfaction and length of hospital stay following cesarean delivery in women with placenta previa.
- Trial name
- NCT07830914
- Testing
- Enhanced Recovery After Surgery Protocol, Conventional perioperative care
- Volunteers
- 100 people
- Sponsor
- Assiut University
Cushing's Disease, Acromegaly
Study to Allow Access to Pasireotide for Patients Benefiting From Pasireotide Treatment in Novartis-sponsored Studies
The purpose of this study is to allow continued use of pasireotide in patients who are on pasireotide treatment in a Novartis-sponsored study and are benefiting from the treatment as judged by the investigator.
- Conditions
- Cushing's Disease, Acromegaly, Neuroendocrine Tumors, Pituitary Tumors
- Trial name
- NCT01794793
- Testing
- Pasireotide, Cabergoline, Pasireotide LAR
- Where
- 94 sites in United States, Argentina and 26 more
- Volunteers
- 337 people
- Sponsor
- RECORDATI GROUP
Myocardial Reperfusion Injury
Remote Ischemic Postconditioning in Humans
The aim of this study is to evaluate the phenomenon of remote ischemic post-conditioning in humans. The minor myocardial damage associated with percutaneous revascularization procedures may be attenuated by producing controlled…
- Trial name
- NCT01113008
- Testing
- Remote ischemic postconditioning, Control group
- Where
- Spain
- Volunteers
- 266 people
- Sponsor
- Hospital Universitario Virgen de la Victoria
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