Clinical trials: Complications; Arthroplasty
Pain, Postoperative
Feasibility of Bridge for Post-Operative Pain Management in Hip Arthroplasty
The aim of this research study is to gather data regarding the feasibility of the Bridge system for the management of pain following total hip arthroplasty (THA).
- Trial name
- NCT05017701
- Testing
- Bridge device
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Masimo Corporation
Arthroplasty Complications, Osteo Arthritis Shoulders
Comprehensive SRS Regenerex Tissue Attachment
The objective of this retrospective and prospective consecutive series data collection is to confirm safety, performance, and clinical benefits of the Comprehensive SRS Regenerex Tissue Attachment Augments when used for limb…
- Trial name
- NCT06615739
- Testing
- Regenerex Tissue Attachment Augments
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Zimmer Biomet
Hip Arthroplasty, Total, Postoperative Pain
Pericapsular Nerve Group Block Versus Intrathecal Morphine for Pain After Hip Surgery
Pain after hip replacement surgery is often severe and is commonly treated with opioids, which may cause nausea, vomiting, sedation, difficulty passing urine and slow breathing.
- Conditions
- Hip Arthroplasty, Total, Postoperative Pain, Hip Arthroplasty, Analgesia
- Trial name
- NCT07784192
- Testing
- Morpine, Ultrasound-guided pericapsular nerve group block, Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Selcuk University
Pain, Postoperative
Liposomal Bupivacaine Versus Interscalene Nerve Block
The aim of this study is to compare two different pain management interventions in patients undergoing reverse total shoulder arthroplasty.
- Trial name
- NCT03929146
- Testing
- Exparel, Interscalene Nerve Block
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Sleep Disturbance, Delirium
Sleep and Cognition After Ambulatory Hip and Knee Arthroplasty
Sleep and rest are key elements in postoperative rehabilitation and recovery. There are complex relations between major surgery, sleep disturbance and complications.
- Conditions
- Sleep Disturbance, Delirium, Arthroplasty Complications
- Trial name
- NCT04227873
- Where
- Denmark
- Volunteers
- 16 people
- Sponsor
- Hvidovre University Hospital
Postoperative Pain, Inflammation
Steroids in Total Knee Arthroplasty
The purpose of this study is to evaluate if the use of two small doses of intravenous (IV) steroids around the time of knee replacement surgery decrease a patient's pain or use of pain medication.
- Conditions
- Postoperative Pain, Inflammation, Osteoarthritis
- Trial name
- NCT02219581
- Testing
- Dexamethasone 10 mg, Dexamethasone 20 mg, Standard multimodal pain management regimen
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Thomas L Bradbury
Physical Disability, Joint Function Disorder
Mexican Initiative of Patients With Osteoarthritis and Rheumatoid Arthritis (IMPACTAR)
The purpose of this study is to evaluate quality of life, degree of disability, treatment patterns and economic impact of hand and knee Osteoarthritis and Rheumatoid Arthritis in Mexico.
- Conditions
- Physical Disability, Joint Function Disorder, Axis IV Problems Economic, Compliance Behavior
- Trial name
- IMPACTAR (NCT02124031)
- Volunteers
- 10,241 people
- Sponsor
- Iniciativa Mexicana de Pacientes con Osteoartritis y Artritis Reumatoide
Pain, Postoperative
Study to Evaluate a Preop Dose of Brivoligide Injection for Pain After Knee Replacement in Patients With High PCS Scores
This is a multi-center, Phase 2, randomized, double-blind, placebo-controlled study to evaluate the safety and efficacy of brivoligide injection administered intrathecally before surgery in patients with a Pain Catastrophizing…
- Trial name
- NCT03797612
- Testing
- Brivoligide Injection 660 mg/6 mL
- Where
- 2 sites in United States
- Sponsor
- Adynxx, Inc.
Arthroplasty, Replacement, Shoulder
Intravenous Dexamethasone Administration in Patients Undergoing Total Shoulder Arthroplasty
The aim of the study is to evaluate if intravenous steroid supplementation can provide advantages over routine analgesia protocols in terms of post-operative symptoms (pain and nausea), length of hospital stay, shoulder range of…
- Trial name
- NCT04507412
- Testing
- dexamethasone
- Where
- Switzerland
- Volunteers
- 74 people
- Sponsor
- Christian Candrian
Post Operative Pain, Regional Block
PENG and LFCN Block Versus Lumbar Plexus Block for Postoperative Analgesia After Total Hip Arthroplasty
Regional anesthesia for postoperative analgesia in THA includes epidural anesthesia and peripheral nerve blocks. However epidural anesthesia has a great role in THA, it has become restricted as perioperative antithrombotic drugs…
- Trial name
- NCT05652075
- Testing
- pericapsular nerve group and lateral femoral cutaneous nerve block, lumbar plexus block
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Minia University
Total Knee Arthroplasty (Postoperative Pain)
REIKI IN TOTAL KNEE ARTHROPLASTY PATIENTS (REIKI TKA )
Total knee arthroplasty (TKA) is commonly performed to improve mobility and quality of life in patients with degenerative joint diseases.
- Trial name
- REIKI TKA (NCT07442435)
- Testing
- Reiki Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ondokuz Mayıs University
Postoperative Pain, Postoperative Nausea and Vomiting
Effects of Methylprednisolone After Total Knee Arthroplasty
The purpose of the study is to compare the effects of pre-operative methylprednisolone (125mg iv) versus placebo on postoperative outcome after knee arthroplasty.
- Conditions
- Postoperative Pain, Postoperative Nausea and Vomiting, Sleeping Quality, Fatigue
- Trial name
- NCT00968578
- Testing
- Methylprednisolone
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Hvidovre University Hospital
Postoperative Delirium
EPO for Postop Delirium in Elderly Patients
Postoperative delirium is a common complication after surgery. The underlying pathophysiology of this complication is unclear, however neuroinflammation and oxidative stress secondary to surgery had shown to be the cause of…
- Trial name
- NCT06178835
- Testing
- Erythropoietin, normal saline
- Where
- South Korea
- Volunteers
- 76 people
- Sponsor
- Yonsei University
Postoperative Pain, Knee Arthroplasty
Postoperative Pain Management After Total Knee Arthroplasty
The study compares three different analgesic techniques in order to determine which one serves as the optimal method for postoperative pain management after Total Knee Arthroplasty in patients suffering from Osteoarthritis
- Trial name
- NCT04344990
- Testing
- Epidural analgesia - Group E, Femoral blockade - Group F, Intraarticular infusion - Group I
- Where
- Greece
- Volunteers
- 72 people
- Sponsor
- University Hospital of Patras
Postoperative Cognitive Dysfunction, Cognitive Impairment
Cognitive Changes After Major Joint Replacement - Full Trial (Cognigram 2)
Patients assume that cognitive performance rapidly returns to baseline after anesthesia and surgery. Several studies have shown that one week after major non-cardiac surgery about 27% of patients have postoperative cognitive…
- Conditions
- Postoperative Cognitive Dysfunction, Cognitive Impairment, Mild Cognitive Impairment, Delirium
- Trial name
- NCT03147937
- Testing
- Cognitive Testing
- Where
- Canada
- Volunteers
- 505 people
- Sponsor
- Dr. Stephen Choi
Osteo Arthritis Knee, Pain, Postoperative
Comparing Single Dose and Multiple Dose of Dexamethasone Post TKA
The goal of this clinical trial is to investigate the efficacy of single dose and double dose of dexamethasone after primary total knee replacement.
- Trial name
- NCT06339151
- Testing
- Dexamethasone before surgery, Dexamethasone before and 12 hours after surgery, Dexamethasone before and 24 hours after surgery
- Where
- Thailand
- Volunteers
- 120 people
- Sponsor
- Thammasat University Hospital
Tensor Fasciae Latae Syndrome, Arthroplasty Complications
Does Vessel-sparing Surgery in Anterior Approach Total Hip Arthroplasty Change Clinical Outcome?
During direct anterior approach (DAA) for total hip arthroplasty (THA), ligation of the lateral femoral circumflex artery and vessel is always conducted.
- Trial name
- USP (NCT06308965)
- Testing
- Vessel sparing technique, Vessel ligation technique
- Where
- Belgium
- Volunteers
- 300 people
- Sponsor
- Ziekenhuis Oost-Limburg
Total Shoulder Arthroplasty
Exparel for Total Shoulder Arthroplasty
The primary objective of this study is to determine if Exparel leads to better pain scores at 24, 48 and 72 hours after Total Shoulder Arthroplasty (TSA) compared to a pain pump.
- Trial name
- NCT04364867
- Testing
- Exparel, Pain Pump
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Norton Healthcare
Hip Fracture, Myocardial Ischemia
Pilot Study of Atorvastatin for Orthopedic Surgery Patients
Up to 35% of hip fracture patients have been shown to experience heart injury after surgery, and as many as 10% have a heart attack or die in the three months after surgery.
- Conditions
- Hip Fracture, Myocardial Ischemia, Inflammation
- Trial name
- POST-OP Pilot (NCT02197065)
- Testing
- Atorvastatin
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Hospital for Special Surgery, New York
Chronic Post-surgical Pain, Chronic Post Operative Pain
Radiofrequency Ablation for the Treatment of Post-knee Arthroplasty Chronic Pain.
Knee osteoarthritis pain is one of the conditions commonly seen in general and specialized medicine. Knee arthroplasty is one of the most successful orthopedic surgeries for the treatment of this disease, significantly improving…
- Conditions
- Chronic Post-surgical Pain, Chronic Post Operative Pain, Chronic Knee Pain
- Trial name
- CSAPG-37 (NCT05920382)
- Testing
- Radiofrequency ablation of peripheral nerves.
- Where
- Spain
- Volunteers
- 86 people
- Sponsor
- Consorci Sanitari de l'Alt Penedès i Garraf