Clinical trials: Complications; Cesarean Section
Postoperative Nausea and Vomiting
Preoperative Oral Carbohydrate for Nausea and Vomiting Prevention During Cesarian Section
Post-operative nausea and vomiting (PONV) in women undergoing subarachnoid anesthesia for Caesarean section is an important clinical problem.
- Trial name
- POC-NaVoP (NCT04069806)
- Testing
- preoperative oral carbohydrate, preOp
- Where
- Poland
- Volunteers
- 140 people
- Sponsor
- Pomeranian Medical University Szczecin
Pressor Response
Dexmedetomidine Nebulization for Attenuation of Pressor Response to Laryngoscopy and Endotracheal Intubation in Sever Preeclamptic Patients
Dexmedetomidine nebulization in sever preeclamptic patients
- Trial name
- NCT07164326
- Testing
- Dexmedetomidine, Saline
- Volunteers
- 100 people
- Sponsor
- Assiut University
Cesarean Section Complications
ESP Block for Post Cesarean Analgesia
The purpose of this pilot study is to assess the analgesic efficacy of Erector Spinae Plane block (ESPB) with liposomal bupivacaine in women undergoing cesarean delivery and receiving a postoperative multimodal analgesic regimen…
- Trial name
- NCT05664958
- Testing
- Erector Spinae Plane (ESP) Block, bupivacaine liposome injectable suspension, bupivacaine
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Duke University
Hemodynamic Instability
Maternal Cardiac Output Response to Rescue Norepinephrine and Phenylephrine Boluses in Patients With Severe Preeclampsia
The purpose of this study is to investigate the maternal cardiac output response to rescue norepinephrine and phenylephrine boluses for postspinal anesthesia hypotension in parturients with preeclampsia undergoing cesarean…
- Trial name
- NCT05035485
- Testing
- Phenylephrine, Norepinephrine
- Where
- China
- Volunteers
- 40 people
- Sponsor
- General Hospital of Ningxia Medical University
Post Partum Hemorrhage
Prophylactic Regimen of Intravenous Oxytocin, Intravenous Tranexamic Acid, and Intramuscular Ergot Derivative for Primary Prevention of Postpartum Hemorrhage in Intrapartum Cesarean Section Versus Intravenous Carbetocin Alone
While Carbetocin is effective in reducing PPH, the combination of oxytocin, Tranexamic acid, and Ergot derivatives may offer additional benefits in high-risk populations.
- Trial name
- NCT07318467
- Testing
- Intravenous Oxytocin, Intravenous Tranexamic Acid, and Intramuscular Ergot Derivative, Intravenous Carbetocin alone
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Obstetrical Complication of Anesthesia
Effects of Intraoperative Oxygen Therapy on Oxygenation of Newborns Born Via Elective Cesarian Section
In this study the investigators examine the effects of intraoperative oxygen administration to the mother on certain enzyme functions of the newborn.
- Trial name
- NCT02804555
- Testing
- Oxygen
- Where
- Hungary
- Volunteers
- 107 people
- Sponsor
- Szeged University
Pain, Postoperative, Caesarean Section
Infiltration Analgesia After Caesarean Section
Infiltration of a local anesthetic into the surgical wound is a simple method to strive to control postoperative pain after surgery. In the investigators institution, this method is used quite often.
- Trial name
- NCT01094106
- Testing
- Ropivacaine 0,75%, NaCl 0,9%
- Where
- Finland
- Volunteers
- 70 people
- Sponsor
- North Karelia Central Hospital
Pain, Postoperative, Cesarean Section
Bilateral Ultrasound-Guided Transversus Abdominis Plane (Tap) Block and Erector Spinal Plane (Esp) Block
Transversus Abdominis Plane Block (TAPB) is frequently used for the management of postoperative pain in patients undergoing cesarean section.
- Conditions
- Pain, Postoperative, Cesarean Section, Erector Spinae Plane Block, Transversus Abdominis Plane Block
- Trial name
- NCT05625009
- Testing
- Procedure/Surgery: Transversus Abdominis Plane Block (TAPB), Procedure/Surgery: Erector Spinae Plane Block (ESPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Istanbul Saglik Bilimleri University
Placenta Previa
ERAS Protocol for Cesarean Delivery in Women With Placenta Previa
This study aims to evaluate the impact of Enhanced Recovery After Surgery protocols on maternal outcomes patient satisfaction and length of hospital stay following cesarean delivery in women with placenta previa.
- Trial name
- NCT07830914
- Testing
- Enhanced Recovery After Surgery Protocol, Conventional perioperative care
- Volunteers
- 100 people
- Sponsor
- Assiut University
Cesarean Section Complications, Hypotension
Noninvasive Continuous Blood Pressure Monitoring for Cesarean Delivery
Noninvasive continuous blood pressure monitoring for preventing post-spinal hypotension during cesarean delivery: A randomized controlled trial
- Trial name
- NCT04752904
- Testing
- ClearSight System
- Where
- South Korea
- Volunteers
- 154 people
- Sponsor
- Seoul National University Hospital
Hypotension Symptomatic, Obstetric Anesthesia Problems
Prevention of Hypotension During Cesarean Section
The aim of this double-blind randomized study will be to compare a fixed-rate prophylactic noradrenaline infusion to a fixed-rate prophylactic phenylephrine infusion during elective cesarean section under combined spinal-epidural…
- Conditions
- Hypotension Symptomatic, Obstetric Anesthesia Problems, Cesarean Section Complications, Vasoconstriction
- Trial name
- NOR-PHEN (NCT03842046)
- Testing
- phenylephrine infusion, norepinephrine infusion
- Where
- 2 sites in Greece
- Volunteers
- 82 people
- Sponsor
- Aretaieion University Hospital
Postoperative Pain
Does Pregabalin Improve Post-operative Pain After C-section Delivery
Pregabalin due to its antihyperalgesic effect, has proven its efficacy on neuropathic pain, essentially in nociceptive surgeries.
- Trial name
- NCT04259073
- Testing
- Pregabalin 150mg, Pregabalin 300mg
- Where
- Tunisia
- Volunteers
- 138 people
- Sponsor
- Hôpital Universitaire Fattouma Bourguiba
Cesarean Section; Infection
Evaluation of Triclosan Coated Suture in Obstetrical Surgery
A prospective comparative randomized blinded study conducted in the obstetrics gynecology department of Ben Arous hospital over an eight-month period between November 2020 and June 2021.
- Trial name
- NCT05330650
- Testing
- Coated Vicryl+, Vicryl
- Where
- Tunisia
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- Tunis University
Cesarean Section Complications
Impact of Maltodextrin on Glycemic and Hemodynamic Management During Cesarean Section
The goal is to evaluate the glycemic and hemodynamic stability in patients undergoing caesarean section in patients treated with maltodextrins two hours before the cesarean section
- Trial name
- MALTO-TC (NCT05553756)
- Testing
- Maltodextrin
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Foggia
Cesarean Section Complications, Cesarean Section Niche
Effect of Decidual Sparing in cs Niche Formation
Assessing the impact of endometrial sparing at double-layer uterine closure as a specific surgical technique in CS to reduce the rate of post-cessarian delivery niche develoment
- Trial name
- NCT06324331
- Testing
- Decidual sparing, Non decidual sparing
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cesarean Section Complications
Carbetocin Versus Oxytocin Infusion Plus Tranexamic Acid During Cesarean Section
Purpose to evaluates the effects of oxytocin infusion with or without intravenous tranexamic acid (TA) in comparison with Carbetocin for prevention of postpartum hemorrhage at a cesarean section with one or more risk factor for…
- Trial name
- NCT03777878
- Testing
- Carbetocin, oxytocin, TA
- Where
- Egypt
- Volunteers
- 400 people
- Sponsor
- Aswan University Hospital
Pregnancy Complications
Risk of Cesarean Section in Primiparous Women Over 35 Years of Age.
The investigators reviewed Saint Thomas Maternity Hospital's database during a 5 year period and compared two cohorts of patients (primiparous women over 35 years of age and primiparous woman between 20 and 34 years of age).
- Trial name
- NCT03771976
- Testing
- Cesarean section, No cesarean section
- Where
- Panama
- Volunteers
- 572 people
- Sponsor
- Saint Thomas Hospital, Panama
Pregnancy, Cesarean Section
Vaginal Birth After Caesarean Section - Effect on Maternal Psychosocial Function
The incidence of caesarean section has reached 15-20% in most developed countries. Encouraging vaginal birth after caesareans section (VBAC) has been considered a key component of a strategy to reduce the caesarean section rate.
- Conditions
- Pregnancy, Cesarean Section, Uterine Rupture
- Trial name
- NCT00517140
- Testing
- Repeat Caesaen section, vaginal delivery
- Where
- China
- Volunteers
- 262 people
- Sponsor
- Hospital Authority, Hong Kong
Postpartum Hemorrhage
Oral Misoprostol Versus Intravenous Oxytocin in Preventing Blood Loss After Non-scheduled Cesarean Section
Postpartum hemorrhage (PPH) ranks among the leading causes of maternal morbidity and mortality, both in developed and developing countries.
- Trial name
- NCT00107874
- Testing
- misoprostol
- Where
- Switzerland
- Volunteers
- 56 people
- Sponsor
- University Hospital, Basel, Switzerland
Endometritis, Wound Infection
Study of Effectiveness and Safety of Azithromycin-based Extended-spectrum Prophylaxis to Prevent Post Cesarean Infection
The Cesarean Section Optimal Antibiotic Prophylaxis (C/SOAP) study is a large pragmatic multi-center randomized clinical trial designed to evaluate the comparative effectiveness and safety of azithromycin-based extended-spectrum…
- Conditions
- Endometritis, Wound Infection, Abscess, Surgical Site Infection
- Trial name
- C/SOAP (NCT01235546)
- Testing
- Azithromycin and standard of care
- Where
- 9 sites in United States
- Volunteers
- 2,013 people
- Sponsor
- Alan Tita
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