Clinical trials: Complications; Cesarean Section
Postoperative Pain
Ropivacaine Transversus Abdominis Plane Blocks for Cesarean Section Analgesia
With this research the investigators hope to determine the lowest dose of ropivacaine used in transversus abdominis plane (TAP) blocks that can effectively treat pain in women after cesarean section (c-section).
- Trial name
- TAPROPI (NCT02893423)
- Testing
- Ropivacaine
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Maimonides Medical Center
Postpartum Hemorrhage, Uterine Atony
Uterine Cooling During Cesarean Delivery to Reduce Blood Loss and Incidence of Postpartum Hemorrhage
The objective of the study is to demonstrate whether cooling the uterine smooth muscle during cesarean section (following delivery of the fetus) will promote better uterine contraction and involution resulting in lower blood…
- Trial name
- NCT02229513
- Testing
- Uterine Cooling
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Opioid Use, Postoperative Pain
Comparison of Postoperative Analgesia Methods in Elective Cesarean Section Surgeries
Since many intravenous anesthetic agents administered to the mother can cross the placental barrier and cause fetal side effects, multimodal analgesia strategies with peripheral nerve blocks are preffered with greater safety in…
- Trial name
- NCT06425718
- Testing
- Postoperative Pain Management Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Marmara University
Cesarean Section Complications
Norepinephrine Infusion Different Doses in Cesarean Delivery
three doses (0.025 mcg/Kg/min, 0.050 mcg/Kg/min, and 0.075 mcg/Kg/min) of norepinephrine will be compared for prophylaxis against Post-spinal anesthesia hypotension during Cesarean delivery.
- Trial name
- NCT03182088
- Testing
- norepinephrine infusion (0.025 mcg/Kg/min), norepinephrine infusion (0.050 mcg/Kg/min), norepinephrine infusion (0.075 mcg/Kg/min)
- Where
- Egypt
- Volunteers
- 284 people
- Sponsor
- Cairo University
Post Operative Pain
Evaluation of the Analgesic Effect of Midazolam and Ketamine as an Additive to Intrathecal Bupivacaine in Patients Undergoing Cesarean Section
Objective :To compare the analgesic effect of intrathecal midazolam and ketamine as an additive to bupivacaine in patients undergoing cesarean section .
- Trial name
- NCT01404442
- Testing
- Ketamine, Midazolam
- Where
- Iran
- Volunteers
- 90 people
- Sponsor
- Qazvin University Of Medical Sciences
Postoperative Nausea and Vomiting
Dexamethasone for the Prevention of Post-operative Nausea and Vomiting in Patients Undergoing Cesarean Sections
Patients who present for scheduled (non-emergent) cesarean section will be given either intravenous dexamethasone or placebo prior to receiving a duramorph containing spinal anesthetic.
- Trial name
- NCT01734161
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Contraception, Dysfunctional Uterine Bleeding
Dysfunctional Uterine Bleeding After Tubal Sterilization
In this study, the investigators will compare the frequency and amount of bleeding after tubal sterilization and salpingectomy
- Trial name
- NCT04396483
- Testing
- Pomeroy's tubal sterilization, Salpingectomy
- Where
- 2 sites in Egypt
- Volunteers
- 220 people
- Sponsor
- Tanta University
Cesarean Section Complications
Towards Enhanced Recovery After Cesarean
One in 300 women will become persistent opioid users after cesarean delivery (1). Cesarean delivery is the most common surgical procedure in the United States, representing 31.9% of the 3,788,235 deliveries in 2018 (2).
- Trial name
- ERAS (NCT04612920)
- Testing
- Ibuprofen, acetaminophen, oxycodone
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Oklahoma
Obesity Complicating Childbirth, Obesity
The MODE Trial: Planned Caesarean Section Versus Induction of Labour for Women With Class III Obesity
Canadian guidelines recommend that women with a pre-pregnancy body mass index (BMI) at or above 40 kg/m2 deliver by their due date.
- Conditions
- Obesity Complicating Childbirth, Obesity, Labor Onset and Length Abnormalities, Pregnancy, High Risk
- Trial name
- MODE (NCT03985618)
- Testing
- Caesarean section, Induction of Labour
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Ottawa Hospital Research Institute
Complications; Cesarean Section, Anesthesia; Adverse Effect, Spinal and Epidural
Fluid Coloading and the Incidence of Hypotension
This study was conducted to evaluate the effects of rapid crystalloid (Lactated Ringer's solution) or colloid (hydroxyethyl starch; HES) cohydration with a second intravenous access line on the incidence of hypotension and…
- Conditions
- Complications; Cesarean Section, Anesthesia; Adverse Effect, Spinal and Epidural, Other Fluid Overload
- Trial name
- NCT01741610
- Testing
- Cristalloid and colloid coloading
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Cesarean Wound Disruption With Postnatal Complication
Impact of Preoperative Bathing on Post Caesarean Section Surgical Site Infection
Surgical site infection (SSI) is the commonest hospital-acquired infection globally, and prevalence is much higher in the low-income countries. Caesarean delivery carries a 5-20 fold risk for developing postpartum sepsis.
- Trial name
- SSI-MUST (NCT03544710)
- Testing
- preoperative bathing with antiseptic
- Where
- Uganda
- Volunteers
- 96 people
- Sponsor
- Mbarara University of Science and Technology
Postpartum Hemorrhage, Twin
Carbetocin at Elective Cesarean Deliveries: A Dose-finding Study in Women With Twin Pregnancy.
Poor uterine tone after the birth of a baby can cause excess bleeding (called postpartum hemorrhage or PPH). This is a major cause of maternal death worldwide.
- Trial name
- NCT04182360
- Testing
- Carbetocin
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Women Who Had at Lease One Cesarean Section in the Past
Relation Between Complication in Repeated Cesarean Sections, Newborn Outcome and Surgical Characteristics and Maternal Information
To examine the relation between complication in Repeated Cesarean Sections and Newborn Outcome compared to number of repeated cesarean section and reasonf or surgery and personal medical information to the mother
- Trial name
- NCT02641574
- Testing
- compare complication
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Postpartum Depression
Postpartum Depression and Cesarean Section
The purpose of this retrospective study is to determine if there is an increase in postpartum depression (PPD) among women who undergo an emergency cesarean section as opposed to a planned cesarean section.
- Trial name
- NCT00370903
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Oklahoma State University Center for Health Sciences
Bowel Ileus, Cesarean Section Complications
Effect of Chewing Gum and Drinking Fennel Tea
Aim: Postoperative ileus after cesarean section is a problem that significantly prolongs hospital stay and increases perioperative costs.
- Trial name
- NCT06403215
- Testing
- Chewing gum group, Fennel tea group, Chewing gum+Fennel tea group
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Marmara University
Cesarean Section Complications, Scar Niche
Uterine Scar Resection During Repeat Cesarean Delivery to Prevent Uterine Niche Formation
The purpose of the study is to evaluate whether resection of the previous cesarean scar at repeat cesarean delivery reduces uterine niche formation and related morbidity without increasing operative risks.
- Conditions
- Cesarean Section Complications, Scar Niche, Scarred Uterus
- Trial name
- NCT07228858
- Testing
- Repeated cesarean section with previous uterine cesarean section scar resection, Repeated cesarean section without uterine scar resection, Saline-infusion Sonohysterography
- Where
- Egypt
- Volunteers
- 170 people
- Sponsor
- Benha University
Postoperative Cognitive Dysfunction
The Effect of Intraoperative Hypotension on Postoperative Cognitive Functions in Cesarean Section Operations
The aim of the study is to see whether the hypotension that develops during spinal anesthesia in cesarean section patients causes a decrease in the postoperative cognitive functions of the patient.
- Trial name
- NCT05843838
- Testing
- Hypotension during spinal anesthesia for cesarean section, Mini-mental test, Spinal anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Cesarean Section Complications, Spinal Anesthesia
Norepinephrine Versus Phenylephrine Continuous Variable Infusion in Cesarean Delivery
Comparison will be conducted between continuous variable infusions of Phenylephrine with starting dose of 0.75 mcg/Kg/min and Norepinephrine Bitartrate with starting dose of 0.1 mcg/Kg/min (with norepinephrine base of 0.05…
- Trial name
- NCT03328533
- Testing
- Phenylephrine, Norepinephrine, Bupivacaine
- Where
- Egypt
- Volunteers
- 123 people
- Sponsor
- Cairo University
Cesarean Section, Pain, Postoperative
Regional Analgesia After Cesarean Section
All patients will be anaesthetized with spinal technique. Each patient will be treated with intravenous morphine - patient controlled analgesia (PCA).
- Conditions
- Cesarean Section, Pain, Postoperative, Pain, Neuropathic
- Trial name
- NCT03244540
- Testing
- TAP (transversus abdominis plane block), QLB (quadratus lumborum block), Stimuplex Ultra 360 needle
- Where
- 2 sites in Poland
- Volunteers
- 105 people
- Sponsor
- Medical University of Lublin
Postoperative Nausea and Vomiting
Effect of Propofol on Postoperative Nausea and Vomiting.
As PONV is an unpleasant experience that badly affects the patients' quality of life after surgery and the anti-emetic effects of propofol have been seldomly studied in Pakistan, this study aims at investigation of the beneficial…
- Trial name
- (PONV) (NCT05071794)
- Testing
- Propofol, saline 0.9%
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pakistan Air Force (PAF) Hospital Islamabad
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