Clinical trials: Complications; Cesarean Section
Placenta Accreta Spectrum
MOGGE PAR Scores for Prediction of Outcomes of PAS
Placenta accreta spectrum (PAS) is a set of placentation disorders that are associated with trophoblastic invasion through the physiologic decidual-myometrial junction zone.
- Trial name
- PAR (NCT04525001)
- Volunteers
- 200 people
- Sponsor
- Assiut University
Cesarean Section; Complications, Wound, Dehiscence
Effects of Abdominal Binders and TENS on Puerperium Period After Cesarean Section
To determine the combined effects of abdominal binders and TENS on post-operative pain, distress and constipation in puerperium period after cesarean section
- Trial name
- NCT06303245
- Testing
- ABDOMINAL BINDERS, TENS
- Where
- Pakistan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Cesarean Section Complications, Pain
Intraabdominal Chloroprocaine During Cesarean Delivery for Pain Control
Objective The objective of this study is to test the hypothesis that instillation of intra-abdominal chloroprocaine during cesarean deliveries is associated with decreased postoperative pain and nausea compared to placebo…
- Trial name
- NCT03260972
- Testing
- Chloroprocaine Hcl 2% Inj, Normal saline
- Sponsor
- Johns Hopkins University
Cesarean Section Complications
Role of Drain in Decreasing Postoperative Complications
postoperative complications are common after cesarean section
- Trial name
- NCT04287933
- Testing
- Drain insertion
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Aljazeera Hospital
Cesarean Section Complications
Tranexamic Acid Plus Buccal Misoprostol on Blood Loss During and After Cesarean Delivery
Postpartum hemorrhage (PPH) is potentially life-threatening and is a significant contributor to maternal mortality and morbidity especially in developing countries.
- Trial name
- NCT03710304
- Testing
- Oxytocin, Tranexamic acid plus misoprostol, misoprostol
- Where
- Egypt
- Volunteers
- 400 people
- Sponsor
- Aswan University Hospital
Venous Thromboembolism, Postpartum Period
The PARTUM Trial: Postpartum Aspirin to Reduce Thromboembolism Undue Morbidity
The goal of the PARTUM trial is to determine if taking low-dose aspirin daily for 6 weeks after delivery is similar (non-inferior) to usual care low-molecular-weight heparin injections to prevent venous thromboembolism (VTE…
- Conditions
- Venous Thromboembolism, Postpartum Period, Aspirin, Low Molecular Weight Heparin
- Trial name
- NCT06494878
- Testing
- Aspirin, Low-molecular-weight heparin
- Where
- 12 sites in Belgium, Canada and 5 more
- Volunteers
- 8,805 people
- Sponsor
- University of Calgary
Postpartum Hemorrhage, Pregnancy Complications
High Or Low Dose pOstpartUm Oxytocin at the Time of Cesarean Birth
This is a study to investigate whether it is feasible to conduct a randomized controlled trial (RCT) of a high dose of oxytocin versus the standard low-dose oxytocin.
- Conditions
- Postpartum Hemorrhage, Pregnancy Complications, Cesarean Section Complications
- Trial name
- HOLDOUT (NCT06550089)
- Testing
- Oxytocin
- Sponsor
- University of Chicago
Pain, Postoperative
Transversalis Fascia Plane Block in Caesarean Section Patients
Transversalis fascia plane block is a regional anesthesia technique described ten years ago. Its use for many indications has been identified by case reports in the literature.
- Trial name
- NCT03741452
- Testing
- transversalis fascia plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Maltepe University
Cesarean Section; Complications, Wound, Hematoma
Suture Material for Closure of Hysterotomy
Retrospective chart review evaluating different suture types on surgical outcomes for cesarean delivery and vaginal birth after cesarean delivery outcomes when different sutures are used.
- Trial name
- NCT03026647
- Testing
- Suture
- Where
- United States
- Sponsor
- St. Louis University
Post Operative Pain
Dexamethasone Administered Via the Epidural Catheter as an Adjunct in Patients Undergoing Cesarean Delivery
This study will evaluate the ability of dexamethasone to enhance labor epidurals when administered as an adjunct to local anesthetics via an epidural catheter.
- Trial name
- NCT03877549
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Obstetric Labor Complications, Hemorrhage
Coagulation Factor Changes Associated With Postpartum Hysterectomies
The purpose of this study is to examine components of the coagulation system in women undergoing postpartum hysterectomy and to compare laboratory parameters of coagulation in these women to women at increased risk for a…
- Conditions
- Obstetric Labor Complications, Hemorrhage, Complications; Cesarean Section
- Trial name
- NCT00456547
- Testing
- Blood Draw
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Ondansetron Lozenge, Postoperative Nausea and Vomiting
Preoperative Ondansetron Lozenge for Prevention of Postoperative Nausea and Vomiting in Caesarean Section
The aim of this study is to estimate the effect of preoperative ondansetron lozenge on prevention of postoperative nausea and vomiting in caesarean section.
- Conditions
- Ondansetron Lozenge, Postoperative Nausea and Vomiting, Caesarean Section
- Trial name
- NCT06254131
- Testing
- Ondansetron lozenge (Ondalenz ©), Ondansetron IV
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Tanta University
Surgical Wound Infection
Alexis O-Ring Wound Retractor for the Prevention of Post-cesarean Surgical Site Infections
Post cesarean section surgical site infection (SSI) is a common complication that can affect patient recovery and overall outcome.
- Trial name
- Alexis (NCT03365219)
- Testing
- Alexis O-Ring Wound Retractor, Standard Surgical Retractors
- Volunteers
- 564 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Cesarean Section Complications
RCT Investigating Pre-cesarean Vaginal Wash of Chlorhexidine vs Povidone-iodine for Patient With Ruptured Amniotic Membrane.
The objective of this study is to investigate if the rate of infectious morbidity is decreased with the use of chlorhexidine or povidone-iodine vaginal scrub before cesarean section after ruptured membranes.
- Trial name
- VAP (NCT03925155)
- Testing
- EZ scrub vaginal chlorhexidine 4% solution, 10% provodine-iodine vaginal preparation
- Volunteers
- healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Labor (Obstetrics)--Complications, Labor; Dyscoordinate
Biomarkers of Uterine Muscle Physiology
This observational study characterizes the relationship between amniotic fluid lactate and uterine electromyography during labor in healthy individuals at term planning a vaginal birth.
- Trial name
- BUMP (NCT04251702)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Cesarean Section Complications
Tranexamic Acid for the Control of Blood Loss at Elective Cesarean Section
The aim of the study is to determine, out of two doses (a standard and a low dose) compared to placebo, the optimal and minimal dose of an intravenously administered single bolus of tranexamic acid(TA) to reduce blood loss when…
- Trial name
- NCT03710330
- Testing
- normal saline, 1gm tranexamic acid, 0.5 gm tranexamic acid
- Where
- Egypt
- Volunteers
- 360 people
- Sponsor
- Aswan University Hospital
Infection Control / Methods, Surgical Site Infection (SSI)
Preoperative Clindamycin Vaginal Cream Versus Vaginal Cleansing With Povidone-iodine on Postoperative Infections After Cesarean Section
To evaluate the effects of preoperative prophylactic administration of clindamycin vaginal cream compared to preoperative vaginal cleansing using a 10% povidone-iodine solution on postpartum infectious morbidity.
- Trial name
- SSI (NCT07474194)
- Testing
- Clindamycin vaginal cream, Vaginal preparation with povidone- iodide solution 10 %
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Beni-Suef University
Pregnancy Related
Different Anesthesia Methods on Development of Postnatal Depression After Cesarean Delivery
Childbirth is one of the most painful experiences for a woman. Labor and period of pregnancy is associated with an increased risk of psychiatric disorders for a woman.
- Trial name
- NCT04565730
- Testing
- Grup I= General anesthesia group, Grup II= Spinal anesthesia group
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Medipol University
Postoperative Infection
RCT of Postoperative Infections Following Caesarean Section Infections Following Caesarean Section
Background Women undergoing Caesarean Section (CS) have an increased risk of postpartum infections compared to women undergoing vaginal delivery. In Denmark the incidence of post-CS infections is 7-10%.
- Trial name
- APIPICS (NCT02009098)
- Testing
- Cefuroxime
- Where
- 3 sites in Denmark
- Sponsor
- Odense University Hospital
Cesarean Section Complications
The Efficacy of Preoperative Low-residue Diet on Postoperative Ileus Following Cesarean Section
The aim of the present study was to evaluate the efficacy of preoperative low-residue diet on postoperative ileus in women undergoing elective cesarean section.
- Trial name
- NCT06320548
- Testing
- Low-residue diet, Free diet
- Where
- Italy
- Volunteers
- 166 people
- Sponsor
- University of Roma La Sapienza
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