Clinical trials: Complications; Cesarean Section
Cesarean Section; Infection, Perineal Infection
Effect of Copper on the Healing of Obstetric Wounds
The most common complication of vaginal delivery is perineal tearing with a prevalence of 85% and 70% will need suturing. The caesarean section rate worldwide is rising and the rate in Croydon University Hospital is in the region…
- Conditions
- Cesarean Section; Infection, Perineal Infection, Wound Infection, Surgical Site Infection
- Trial name
- ECHO (NCT03284749)
- Testing
- Copper impregnated wound dressing, Normal wound dressing, Copper impregnated maternity pads
- Where
- United Kingdom
- Volunteers
- 774 people
- Sponsor
- Croydon Health Services NHS Trust
Pain, Postoperative, Cesarean Section
Bilateral Ultrasound-Guided Transversus Abdominis Plane (Tap) Block and Erector Spinal Plane (Esp) Block
Transversus Abdominis Plane Block (TAPB) is frequently used for the management of postoperative pain in patients undergoing cesarean section.
- Conditions
- Pain, Postoperative, Cesarean Section, Erector Spinae Plane Block, Transversus Abdominis Plane Block
- Trial name
- NCT05625009
- Testing
- Procedure/Surgery: Transversus Abdominis Plane Block (TAPB), Procedure/Surgery: Erector Spinae Plane Block (ESPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Istanbul Saglik Bilimleri University
ıntrapartum Haemorrhage, Postpartum Haemorrhage
The Effect of Rectal and Sublingual Misoprostol Administration in Postpartum or Intrapartum Haemorrhage at Elective Caesarean Delivery: a Randomized Controlled Trial
The investigators hypothesis in this study is that administration of rectal and sublingual misoprostol decreases intrapartum and postpartum haemorrhage.
- Trial name
- NCT01931410
- Testing
- Misoprostol
- Volunteers
- 618 people
- Sponsor
- Istanbul Bakirkoy Maternity and Children Diseases Hospital
Uterine Rupture Gravid
Uterine Rupture International Data Acquisition
Uterine rupture represents an uncommon event: it is is a life-threatening obstetric complication with high maternal and perinatal morbidity and mortality.
- Trial name
- URIDA (NCT03576950)
- Volunteers
- 100 people
- Sponsor
- Università degli Studi dell'Insubria
Cesarean Delivery, Postpartum Comfort
Post-cesarean Analgesia: Comparing Effectiveness of Staggered v. Simultaneous Therapies
Cesarean delivery is a commonly performed surgical procedure associated with worse postpartum pain when compared to vaginal birth. Uncontrolled postpartum pain is associated with increased neonatal and maternal risks.
- Conditions
- Cesarean Delivery, Postpartum Comfort, Postpartum Pain, Post-operative Pain
- Trial name
- PACESS (NCT07102641)
- Testing
- Acetaminophen, NSAID (Ketorolac/Ibuprofen)
- Where
- United States
- Volunteers
- 825 people
- Sponsor
- Thomas Jefferson University
Isthmocele, Cesarean Scar Defect
Clinical Impact of Uterine Repair During Cesarean Section with Barbed Suture on the Incidence of Isthmocele
Pregnant women, irrespective of their pregnancy risk, who undergo a cesarean section for any reason will be randomized to one of two suturing techniques: conventional suture or barbed suture for uterine repair after the cesarean…
- Conditions
- Isthmocele, Cesarean Scar Defect, Pelvic Pain, Spotting
- Trial name
- CESARIS (NCT06691750)
- Testing
- Barbed suture, Conventional smooth suture
- Where
- Spain
- Volunteers
- 364 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Obesity, Wound Infection
Kerlix for Pregnant Women With Elevated BMI to Prevent Wound Infection by 6 Weeks Post Partum
Pregnant women with BMI>40 will be approached for participation in a study to reduce the rate of post-operative wound infection from C-section.
- Conditions
- Obesity, Wound Infection, Pregnancy
- Trial name
- NCT02882360
- Testing
- Kerlix-AMD
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Obstetric Labor Complications
Dynamic Ultrasound for Prediction of Adhesion Section
1. To validate the use of dynamic ultrasound for prediction of adhesions in women undergoing repeated cesarean section. 2. To detect the interobserver and intraobserver reliability of this method
- Trial name
- NCT03862820
- Testing
- dynamic ultrasound
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cesarean Section Complications
Carbetocin Versus Oxytocin Infusion Plus Tranexamic Acid During Cesarean Section
Purpose to evaluates the effects of oxytocin infusion with or without intravenous tranexamic acid (TA) in comparison with Carbetocin for prevention of postpartum hemorrhage at a cesarean section with one or more risk factor for…
- Trial name
- NCT03777878
- Testing
- Carbetocin, oxytocin, TA
- Where
- Egypt
- Volunteers
- 400 people
- Sponsor
- Aswan University Hospital
Postoperative Pain, Cesarean Section Complications
Effect of Quadratus Lumborum Block in C/S
to compare postoperative analgesic effects of USG guided QLB-2 and QLB-3 blocks after C/S. We hypothesized that QLB-3 may be more effective for pain relieving than QLB-2 after C/S.
- Conditions
- Postoperative Pain, Cesarean Section Complications, Block, Patient Satisfaction
- Trial name
- NCT04733313
- Testing
- ultrasound guıded quadratus lumborum block
- Where
- Turkey (Türkiye)
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Cesarean Section; Infection
Evaluation of Triclosan Coated Suture in Obstetrical Surgery
A prospective comparative randomized blinded study conducted in the obstetrics gynecology department of Ben Arous hospital over an eight-month period between November 2020 and June 2021.
- Trial name
- NCT05330650
- Testing
- Coated Vicryl+, Vicryl
- Where
- Tunisia
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- Tunis University
Pressor Response
Dexmedetomidine Nebulization for Attenuation of Pressor Response to Laryngoscopy and Endotracheal Intubation in Sever Preeclamptic Patients
Dexmedetomidine nebulization in sever preeclamptic patients
- Trial name
- NCT07164326
- Testing
- Dexmedetomidine, Saline
- Volunteers
- 100 people
- Sponsor
- Assiut University
Postoperative Pain
Transversus Abdominis Plane Block Versus Rectus Sheath Block After Cesarean Delivery
Importance of effective postoperative pain management is well known. The undesired effects of pain can be prevented with multimodal analgesia for the patient.
- Trial name
- NCT03811067
- Testing
- Transversus abdominis plane block, Rectus sheath block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Kocaeli University
Cesarean Section Complications
EFFECT OF SCAR RELEASE TECHNIQUES ON CHRONIC SCAR PAIN AND MOBILITY POST CESAREAN SECTION
Purpose of the study: The aim of this study is to determine the effect of scar release techniques on chronic scar pain and mobility post cesarean section.
- Trial name
- NCT05391685
- Testing
- Scar release techniques + therapeutic ultrasound
- Volunteers
- 40 people
- Sponsor
- Cairo University
Anesthetic Complication Spinal
Variable Rate Phenylephrine Infusion for Prevention of Spinal-induced Hypotension for Cesarean Delivery
Rapid administration of crystalloid immediately after induction of spinal anesthesia (coload) to be more effective in terms of managing hypotension as compared to administering crystalloid before spinal anesthesia (preload).
- Trial name
- NCT01378325
- Testing
- Phenylephrine, saline
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Cesarean Section Complications
Effect of Preoperative Oral Energy Drinks Compared to Warming Matress on Body Temperature During Combined Spinal-epidural Anesthesia for Elective Cesarean Delivery.
It is not known which is better for intraoperative temperature protection, warming matress or preoperative oral functional drinks in elective cesarean section.
- Trial name
- NCT06017076
- Testing
- Oral energy drinks, Warming matress
- Where
- China
- Volunteers
- 302 people
- Sponsor
- Peking University People's Hospital
Uterine Atony With Hemorrhage, Postpartum Hemorrhage
Uterine Preservation With Acar's Atony Suture for Postpartum Uterine Hemorrhage
This study is aimed to show effectiveness of a new suture technique to stop postpartum uterine bleeding due to uterine atony.
- Trial name
- NCT06353074
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people
- Sponsor
- Necmettin Erbakan University
Pregnancy, Severe Pre-eclampsia
Dexmedetomidine vs. Remifentanil for Pre-eclampsia During Caesarean Delivery
Preeclampsia is a pregnancy-specific, multisystem disorder that complicates approximately 5 % of pregnancies. Tracheal intubation in the women with severe pre-eclampsia is usually associated with exaggerated transient increases…
- Trial name
- NCT01766089
- Testing
- Remifentanil, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Mansoura University
Misoprostol Allergy
Pre Versus Post-operative Misoprostol in Reducing Blood Loss After Cesarean Section
Cesarean section is the most common performed major surgical interventions among women all over the world.Cesarean section has many serious complications, including primary postpartum hemorrhage (PPH).
- Trial name
- NCT05928871
- Testing
- Misoprostol 200mcg Tab, Misoprostol Pill
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Cairo University
Complications; Cesarean Section
Methods of Placental Delivery and the Amount of Blood Loss During Cesarean Section
To compare between the effect of controlled cord traction and manual removal of the placenta on blood loss among women undergoing caesarean sections
- Trial name
- NCT02405663
- Testing
- manual removal, cord traction
- Where
- Saudi Arabia
- Volunteers
- 288 people
- Sponsor
- Benha University
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